Allergen Details
| Allergen name: | Equ c 6 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Chordata Order: Perissodactyla Species: Equus caballus (Domestic horse) NCBI Taxomony ID: 9796 |
| Biochemical name: | Lysozyme |
| MW(SDS-PAGE): | 15 kDa |
| Allergenicity: | IgE positive responses to purified lysozyme of horse (Equus caballus) and donkey (Equus asinus), 1 patient with dermal (urticaria) reactions to creams containing donkey milk, the second with dermatis following exposure to donkey milk in cosmetics and angioedema after ingesting a few drops of donkey milk. The horse and donkey lysozymes are 99% identical. The two patients had ~ IgE to pure donkey and horse lysozyme, a bit more reactivity in BAT to donkey. Seems both dermal and food allergens. |
| Allergenicity reference: | PubMed:30004599 |
| Route of allergen exposure: | Contact |
| Created: | 2017-12-14 20:45:15 |
| Last Updated: | 2020-05-14 23:42:36 |
| Submitter Info: | |
| Name: | Kyra Swiontek, Christiane Hilger |
| Institution: | Luxembourg Institute of Health, Dept. of Infection and Immunity |
| City: | Esch-sur-Alzette, Luxembourg |
| Email: | kyra.swiontek@lih.lu, christiane.hilger@lih.lu |
| Submission Date: | 2017-12-06 |
Comments
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Equ c 6.01 | P11376 | 2EQL |