Allergen Details
| Allergen name: | Cra g 1 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Mollusca Order: Ostreida Species: Crassostrea gigas [Magallana gigas] (Pacific oyster) NCBI Taxomony ID: 29159 |
| Obsolete name: | actin bindnig protein |
| Biochemical name: | tropomyosin |
| MW(SDS-PAGE): | 38 kDa |
| Allergenicity: | Serum donors reported allergic symptoms when eating molluscs or crustaceans, were tested by SPT with extract of source, serum IgE by western blot, 5 positive IgE binders out of 10 subjects, and 3 negative controls, using natural and recombinant protein made in E. coli. |
| Route of allergen exposure: | Food |
| Created: | 2017-09-20 14:37:03 |
| Last Updated: | 2019-08-03 00:29:36 |
| Submitter Info: | |
| Name: | Roni Nugraha, Andreas Lopata |
| Institution: | James Cook University |
| City: | Townsville, Australia |
| Email: | roni.nugraha@my.jcu.edu.au, andreas.lopata@jcu.edu.au |
| Submission Date: | 2017-09-06 |
Comments
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Cra g 1.0101 | KY549366.1 | ARX70262.1 | ||
| Cra g 1.0102 | AB444943.1 | BAH10152.1 |
Note Nugraha and Lopata submitted to WHO/IUIS in Sept. 2017, earning Cra G 1.0101. Emoto et al., did not submit, but published sequence and information in 2009, so that was added as isoform 1.0102 with 95% identity.