ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Der p 13
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Sarcoptiformes
Species: Dermatophagoides pteronyssinus (European house dust mite)
NCBI Taxomony ID: 6956
Biochemical name:Cytosolic Fatty Acid Binding Protein
MW(SDS-PAGE):15 kDa
Allergenicity:224 "HDM-allergic" subjects living in Thailand, with rhinitis or asthma were tested for IgE binding to Dermatophagoides pteronyssinus ImmunoCAP and were class 3 or higher. Serum IgE binding to recombinant Der p 13 produced in Picchia, were tested by ELISA with 15 of 224 positive.
Route of allergen exposure:Airway
Created:2016-03-15 12:00:00
Last Updated:2019-08-15 22:16:40
Submitter Info:
Name:Alain P.A. Jacquet
Institution:Chulalongkorn University, Dept. of Medicine
City:Bangkok, Thailand
Email:alain.j@chula.ac.th
Submission Date:2016-03-09

Comments

Posted: 16 Mar 2016

Sequences were originally from Heinrich,T., Smith,W.-A. and Thomas,W.R. in 2010. A. Jacquet indicates the submitter constructed a rDNA in Picchia pastoris, expressed and used the protein in tests. They indicate 90% sequence coverage by MSMS.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Der p 13.0101HM560018ADK92390E0A8N8