WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Ara h 15
Allergen source: Major taxonomic group: Plantae Eudikotyledons
Order: Fabales
Species: Arachis hypogaea (Peanut, groundnut)
NCBI Taxomony ID: 3818
Obsolete name:Oleosin 3
Biochemical name:Oleosin
Allergenicity:15 of 33 subjects with peanut allergy had demonstrable IgE binding to this protein (based on communication with submission)
Allergenicity reference:PubMed:25860789PubMed:28342912
Route of allergen exposure:Food
Date Created:27-03-2015
Last Updated:2020-05-14 17:16:37
Submitter Info:
Name:Uta Jappe, Christian Schwager, Skadi Kull, Susanna Krause, Frauke Schocker, Arnd Petersen, Wolf-Meinhard Becker
Institution:Research Center Borstel, Division of Clinical and Molecular Allergology, Research Center Borstel, Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL)
City:Borstel, Germany
Submission Date:2015-03-27


Posted: 02 May 2015

From submission: Results obtained from N-terminal sequencing and peptide mass fingerprinting of the protein gave reliable evidence that this proteins refers to the amino acid sequence from Uniprot Q647G3, a peanut oleosin. Therefore, a new allergen name is suggested. Sequence identity to the registered peanut oleosins Ara h 10 and Ara h 11 is below 48%. In addition, the sequence identity to the submitted allergen Ara h 14 is below 30 % (Alignments were performed using ClustalW2,

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Ara h 15.0101AY722696AAU21501Q647G3