ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Der f 28
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Sarcoptiformes
Species: Dermatophagoides farinae (American house dust mite)
NCBI Taxomony ID: 6954
Biochemical name:Heat shock protein Hsp70
MW(SDS-PAGE):70 kDa
Allergenicity:Serum IgE binding in 28 of 41 HDM allergic subjects, with SPT+ in 7 of 10 to rDer f 28. Also BAT positive in a few subjects.
Allergenicity reference:PubMed:23481662
Route of allergen exposure:Airway
Created:2014-11-04 12:00:00
Last Updated:2023-11-22 18:14:14
Submitter Info:
Name:Su An
Institution:Kunming Institute of Zoology, Chinese Academy of Sciences
City:Kunming, China
Email:aslxj@mail.ustc.edu.cn
Submission Date:2013-10-17

Comments

Posted: 05 Nov 2014

The overall identity match of Der f 28.0101 and Der f 28.0201 is ~ 57%, which is beyond the normal range for isoallergens in IUIS, however, the first 3/4 of the sequences are of much higher identity, warranting the designation.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Der f 28.0101KC305502AGC56218.1L7V065 
Der f 28.0201KM009992AIO08848.1