Allergen Details
| Allergen name: | Der f 28 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Arthropoda Order: Sarcoptiformes Species: Dermatophagoides farinae (American house dust mite) NCBI Taxomony ID: 6954 |
| Biochemical name: | Heat shock protein Hsp70 |
| MW(SDS-PAGE): | 70 kDa |
| Allergenicity: | Serum IgE binding in 28 of 41 HDM allergic subjects, with SPT+ in 7 of 10 to rDer f 28. Also BAT positive in a few subjects. |
| Allergenicity reference: | PubMed:23481662 |
| Route of allergen exposure: | Airway |
| Created: | 2014-11-04 12:00:00 |
| Last Updated: | 2023-11-22 18:14:14 |
| Submitter Info: | |
| Name: | Su An |
| Institution: | Kunming Institute of Zoology, Chinese Academy of Sciences |
| City: | Kunming, China |
| Email: | aslxj@mail.ustc.edu.cn |
| Submission Date: | 2013-10-17 |
Comments
Table of Isoallergens
Click on the arrows to show the details of individual isoallergens, click on +/- to show/hide the details of all isoallergens.
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Der f 28.0101 | KC305502 | AGC56218.1 | L7V065 | |
| Der f 28.0201 | KM009992 | AIO08848.1 |
The overall identity match of Der f 28.0101 and Der f 28.0201 is ~ 57%, which is beyond the normal range for isoallergens in IUIS, however, the first 3/4 of the sequences are of much higher identity, warranting the designation.