ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details

Allergen name: Der f 8
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Sarcoptiformes
Species: Dermatophagoides farinae (American house dust mite)
NCBI Taxomony ID: 6954
Biochemical name:Glutathione S-transferase
MW(SDS-PAGE):32 kDa
Allergenicity:Asthmatic patients selected (41) by SPT to extract of D. farinae, then tested by ImmunoCAP, a pool of sera of DP + subjects had clear IgE binding on 2D gel electrophoresis.
Allergenicity reference:PubMed:23481662
Route of allergen exposure:Airway
Created:2014-10-28 12:00:00
Last Updated:2019-08-15 01:11:20
Submitter Info:
Name:Su An
Institution:Kunming Institute of Zoology, Chinese Academy of Sciences
City:Kunming, China
Email:aslxj@mail.ustc.edu.cn
Submission Date:2013-10-17

Comments

Posted: 29 Oct 2014

Limited allergenicity data, based on 2D immunoblot with pooled sera. However, 86% sequence identity to well proven D. pteronyssinus, Der p 8 glytathione S-transferase. Appears to be a partial sequence, no signal peptide.

Table of Isoallergens

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Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Der f 8.0101KC305499AGC56215