Allergen Details
| Allergen name: | Ara h 2 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Fabales Species: Arachis hypogaea (Peanut, groundnut) NCBI Taxomony ID: 3818 |
| Biochemical name: | Conglutin (2S albumin) |
| MW(SDS-PAGE): | 17 kDa |
| Allergenicity: | Of 40 peanut-allergic patients tested, 34 (85%) showed IgE binding to rAra h 2 on immunoblot. - In ELISA of partially purified Ara h 2, all 6 peanut-allergic patients tested had IgE Ab against Ara h 2: medline 93094482. - IgE binding epitopes: medline 22092281 and medline 97330026 |
| Allergenicity reference: | PubMed:10474031 PubMed:918645 PubMed:12759484 |
| Route of allergen exposure: | Food |
| Created: | 2003-10-27 12:00:00 |
| Last Updated: | 2020-05-14 17:05:37 |
| Submitter Info: | |
| Name: | JS Stanley |
| Institution: | University of Arkansas |
| City: | Little Rock, AR, USA |
| Email: | |
| Submission Date: | 2003-10-27 |
Comments
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Ara h 2.0101 | AY007229 | AAK96887 | ||
| Ara h 2.0201 | AY158467 | AAN77576 | Q6PSU2-1 |
A number of laboratories contributed to sequencing and allergenicity of the the 2S albumins from peanut, called Ara h 2. The AW Burks lab in Arkansas, Wolf-Becker's lab in Germany, the Chatel lab INRA, in France and the Visquez group in Alabama among others. We do not have a record of the original submission.