Allergen Details:
| Allergen name: | Bla g 3 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Arthropoda Order: Blattodea Species: Blattella germanica (German cockroach) |
| Biochemical name: | Hemocyanin, Arylphorins/TO Arthropod hemocyanins |
| MW(SDS-PAGE): | 78.9 kDa (by mass spectrometry) |
| Allergenicity: | 22% of 61 sera from cockroach-allergic adult subjects with a positive skin prick test to B. germanica extract had IgE that bound to recombinant Bla g 3.0101 (E. coli product) in ELISA. |
| Allergenicity reference: | PubMed:24468254 |
| Route of allergen exposure: | Airway |
| Date Created: | 18-09-2012 |
| Last Updated: | 2020-03-24 19:03:02 |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Bla g 3.0101 | GU086323 | ACY40651 | D0VNY7 |
Bla g 3.0101 is the only isoform currently in database. It has been published as Bla g 3.02 because it was the variant 2 that FT Chew cloned. There is another variant 1. The variant 2 (GU086323) is ~75-80% more abundant in cockroach extract as analyzed by Samuel Mindaye of the FDA.