ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Tyr p 34
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Sarcoptiformes
Species: Tyrophagus putrescentiae (Storage mite)
NCBI Taxomony ID: 59818
Obsolete name:Tyr p 24
Biochemical name:Troponin C
MW(SDS-PAGE):18 kDa
Allergenicity:Sera of 5/47 (10.6%)of the tested patients had IgE that reacted with the recombinant Tyr p 24.0101 in ELISA.The diagnosis of teh patients was based on case history and skin prick testing. All 47 patients had IgE against T. putrescentiea extract as confirmed by ImmunoCAP. 22 subjects suffered from rhinitis, 14 from asthma, 1 from dizziness, 1 from bronchitis, and 1 from hypereosinophilia.
Allergenicity reference:PubMed:19786801
Route of allergen exposure:Airway
Created:2009-02-26 12:00:00
Last Updated:2019-09-27 08:54:51
Submitter Info:
Name:Jeong KY; Yong TS
Institution:Institute of Tropical Medicine
City:Seoul, Korea
Email:tsyong212@yumc.yonsei.ac.kr
Submission Date:

Comments

Posted: 07 Dec 2015

The designation of Troponin C of Tyrophagus putrescentiae was changed to Tyr p 34 (from Tyr p 24) on 7 Dec 2015 to provide a consistent number for troponin c across mites (e.g. HDM).

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Tyr p 34.0101FJ534553ACL36923D2DGW3