Allergen Details
| Allergen name: | Tyr p 34 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Arthropoda Order: Sarcoptiformes Species: Tyrophagus putrescentiae (Storage mite) NCBI Taxomony ID: 59818 |
| Obsolete name: | Tyr p 24 |
| Biochemical name: | Troponin C |
| MW(SDS-PAGE): | 18 kDa |
| Allergenicity: | Sera of 5/47 (10.6%)of the tested patients had IgE that reacted with the recombinant Tyr p 24.0101 in ELISA.The diagnosis of teh patients was based on case history and skin prick testing. All 47 patients had IgE against T. putrescentiea extract as confirmed by ImmunoCAP. 22 subjects suffered from rhinitis, 14 from asthma, 1 from dizziness, 1 from bronchitis, and 1 from hypereosinophilia. |
| Allergenicity reference: | PubMed:19786801 |
| Route of allergen exposure: | Airway |
| Created: | 2009-02-26 12:00:00 |
| Last Updated: | 2019-09-27 08:54:51 |
| Submitter Info: | |
| Name: | Jeong KY; Yong TS |
| Institution: | Institute of Tropical Medicine |
| City: | Seoul, Korea |
| Email: | tsyong212@yumc.yonsei.ac.kr |
| Submission Date: | |
Comments
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Tyr p 34.0101 | FJ534553 | ACL36923 | D2DGW3 |
The designation of Troponin C of Tyrophagus putrescentiae was changed to Tyr p 34 (from Tyr p 24) on 7 Dec 2015 to provide a consistent number for troponin c across mites (e.g. HDM).