WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Phl p 5
Allergen source: Major taxonomic group: Plantae Liliopsida (monocots)
Order: Poales
Species: Phleum pratense (Timothy)
NCBI Taxomony ID: 15957
Allergenicity:95% of grass pollen-allergic patients (98 tested) showed IgE binding to Phl p 5 in immunoblot of pollen extract; 97/98 subjects showed IgE binding to rPhl p 5 on nitrocellulose filters. - all patients (11) with positive skin prick test responses to grass pollen allergens reacted to the C-terminal, and 73% react to the N-terminal peptide of Phl p 5a. - Purified rPhl p 5 elicited dose-dependent basophil histamine release in 1 patient tested, and immediate type skin reactions in 4 patients test
Allergenicity reference:PubMed:1597349
Route of allergen exposure:Airway
Date Created:13-02-2003
Last Updated:2019-09-05 22:45:36
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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Phl p 5.0101X74735CAA52753Q409602M64
Phl p 5.0102X70942CAA50281Q40962 
Phl p 5.0103AF069470AAC25994O81341 
Phl p 5.0104Z82986CAB05372P93467 
Phl p 5.0105AF061066AAC16525O65318 
Phl p 5.0106AF061067AAC16526O65319 
Phl p 5.0107AF061068AAC16527O65320 
Phl p 5.0108AF061069AAC16528O65321 
Phl p 5.0109AJ555152CAD87529Q84UI2 
Phl p 5.0201Z27083CAA81609Q409631L3P
Phl p 5.0202Z82985CAB05371P93466 
Phl p 5.0203AF069471AAC25995O81342 
Phl p 5.0204    
Phl p 5.0205    
Phl p 5.0206AF069473AAC25997O81343 
Phl p 5.0207AF069474AAC25998O81344