ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Act d 1
Allergen source: Major taxonomic group: Plantae Eudikotyledons
Order: Ericales
Species: Actinidia deliciosa (Green kiwi fruit)
NCBI Taxomony ID: 3627
Obsolete name:Act c 1
Biochemical name:Cysteine protease (actinidin)
MW(SDS-PAGE):30 kDa
Allergenicity:All 30 sera of kiwi-allergic patients tested, showed IgE binding to a 30 kD protein on immunoblot of kiwi extract (medline 96426244). This protein was later identified as Act c 1.
Allergenicity reference:PubMed:9564807
Route of allergen exposure:Food
Created:2007-02-09 12:00:00
Last Updated:2020-05-13 17:56:21
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Comments

Posted: 16 Aug 2023

This entry replaces the previous Act c 1 entry. The Act c 1 entry was removed from the database, as Act c 1 was renamed to Act d 1 in 2007. The new name reflects the updated taxonomy of kiwifruit species, separating Actinidia deliciosa from Actinidia chinensis. In contrast to A. deliciosa, A. chinensis contains only low amounts of actinidin.
Christian Radauer, science co-chair

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Act d 1.0101X16466CAA34486P007852ACT 1AEC