Allergen Details:
| Allergen name: | Act d 1 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Ericales Species: Actinidia deliciosa (Green kiwi fruit) |
| Obsolete name: | Act c 1 |
| Biochemical name: | Cysteine protease (actinidin) |
| MW(SDS-PAGE): | 30 kDa |
| Allergenicity: | All 30 sera of kiwi-allergic patients tested, showed IgE binding to a 30 kD protein on immunoblot of kiwi extract (medline 96426244). This protein was later identified as Act c 1. |
| Allergenicity reference: | PubMed:9564807 |
| Route of allergen exposure: | Food |
| Date Created: | 09-02-2007 |
| Last Updated: | 2020-05-13 17:56:21 |
| Submitter Info: | |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Act d 1.0101 | X16466 | CAA34486 | P00785 | 2ACT 1AEC |
This entry replaces the previous Act c 1 entry. The Act c 1 entry was removed from the database, as Act c 1 was renamed to Act d 1 in 2007. The new name reflects the updated taxonomy of kiwifruit species, separating Actinidia deliciosa from Actinidia chinensis. In contrast to A. deliciosa, A. chinensis contains only low amounts of actinidin.
Christian Radauer, science co-chair