ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details

Allergen name: Per a 1
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Blattodea
Species: Periplaneta americana (American cockroach)
NCBI Taxomony ID: 6978
Obsolete name:Cr-PII
Biochemical name:Nitrile-specifier, microvilli-like protein with unknown function
MW(SDS-PAGE):45 kDa
Allergenicity:Of 35 allergic patients, 22 had a positive skin test to CR-extract and Per a 1. Of these 22 patients, 12 (54.4%) showed a positive skin reaction to rPer a 1. IgE Ab binding to rPer a 1 was demonstrated in ELISA. - Amino acid sequences 78LIRALFGL85 and 267IRSWFGLP1274 of the American cockroach Per a 1.0104 allergen were involved in IgE binding, as measured by ELISA. 80%-100% of the sera tested showed IgE binding to these peptides.
Allergenicity reference:PubMed:10221434PubMed:10329820
Route of allergen exposure:Airway
Created:2003-05-16 12:00:00
Last Updated:2022-06-14 14:56:08
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Table of Isoallergens

Click on the arrows to show the details of individual isoallergens, click on +/- to show/hide the details of all isoallergens.

Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Per a 1.0101AF072222AAD13533Q9TZR6 
Per a 1.0102U78970AAC34312O18535 
Per a 1.0103U69957AAB82404O18530 
Per a 1.0104U69261AAC34737O18528 
Per a 1.0201U69260AAC34736O18527