Allergen Details
| Allergen name: | Hev b 2 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Malpighiales Species: Hevea brasiliensis (Para rubber tree (latex)) NCBI Taxomony ID: 3981 |
| Biochemical name: | beta-1,3-glucanase; glucan endo-1,3-beta-glucosidase, basic vacuolar isoform |
| MW(SDS-PAGE): | 35, 36.5 and 38 kDa |
| Allergenicity: | Pubmed:9525455: Of 15 latex allergic patients, 6 (40%) reacted with purified nHev b 2 in immunoblot and ELISA. - PubMed:12372996: All sera of 34 latex sensitized patients also sensitized to nHev b 2 bound to three separated isoforms in ELISA. In immunoblot, only the glycosylated isoforms I and II, but not the non-glycosylated isoform III were recognized. In SPT, 3-4 of 7 patients reacted with the isoforms. |
| Allergenicity reference: | PubMed:9525455 PubMed:12372996 |
| Route of allergen exposure: | Contact |
| Created: | 2003-07-03 12:00:00 |
| Last Updated: | 2019-07-17 18:36:27 |
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Comments
Table of Isoallergens
Click on the arrows to show the details of individual isoallergens, click on +/- to show/hide the details of all isoallergens.
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Hev b 2.0101 | U22147 | AAA87456 | P52407 |