ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Dol m 2
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Hymenoptera
Species: Dolichovespula maculata (White face hornet)
NCBI Taxomony ID: 7441
Biochemical name:Hyaluronidase
MW(SDS-PAGE):42 kDa
Allergenicity:Of 11 vespid-allergic patients tested, 7 were skin test positive to purified white hornet hyaluronidase. >20% basophil histamine release was induced in 81% of patients tested. J Gadde, DBK Golden, A Kagey-Sobotka, MD Valentine, LM Lichtenstein, TP King. 1986. J Allergy Clin Immunol 77, 143. Abstract. - Of 17 D. maculata-allergic patients, 13 showed IgE binding to purified Dol m 2 (identified by hyaluronidase activity) in RAST.
Allergenicity reference:PubMed:3989146
Route of allergen exposure:Injection
Created:2003-05-31 12:00:00
Last Updated:2019-08-15 23:19:09
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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Dol m 2.0101L34548AAA68279P49371