ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details

Allergen name: Act c 5
Allergen source: Major taxonomic group: Plantae Eudikotyledons
Order: Ericales
Species: Actinidia chinensis (Gold kiwi fruit)
NCBI Taxomony ID: 3625
Biochemical name:Kiwellin
MW(SDS-PAGE):28 kDa
Allergenicity:Sera from six individual kiwi-allergic subjects (with positive SPT and IgE CAP) showed IgE binding to purified kiwellin from both green kiwi fruit and gold kiwi fruit on immunoblot.
Allergenicity reference:PubMed:18442249
Route of allergen exposure:Food
Created:2008-07-08 12:00:00
Last Updated:2019-06-28 08:09:27
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Comments

Posted: 10 Sep 2014

The amino acid sequence by Tuppo et al. as P85261 is partial and discontinuous (34aa). In the second part of the discontinuous sequence in the Tuppo paper, there two probable amino acid mismatches with the sequence reported for kiwellins by Maddumage et al. JAFC 2013. which has been added as a separate isoform Act c 5.0102.

Table of Isoallergens

Click on the arrows to show the details of individual isoallergens, click on +/- to show/hide the details of all isoallergens.

Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Act c 5.0101 P85261.1P852614PMK
Act c 5.0102JX905294.1AGC39168.1L7TT83