WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Der p 11
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Sarcoptiformes
Species: Dermatophagoides pteronyssinus (European house dust mite)
NCBI Taxomony ID: 6956
Biochemical name:Paramyosin
MW(SDS-PAGE):103 kDa
Allergenicity:The prevalence of serum IgE reactivity to rDer p 11 on immunodot assay ranged from 41.7% to 66.7% in different allergic patient groups, whereas it was rare in non-atopic patients with urticaria (18.8%) and in normal individuals (8%). A high frequency (five out of eight) of MAST(Dp)- allergic serum samples had specific IgE-binding activity to rDer p 11 or its fragments on immunoblot assay, even though their IgE-binding activity to Dp extract was either weak or negative.
Allergenicity reference:PubMed:15005727
Route of allergen exposure:Airway
Created:2006-11-05 12:00:00
Last Updated:2019-08-15 22:11:56
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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Der p 11.0101AY189697AAO73464Q6Y2F9