WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Der f 2
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Sarcoptiformes
Species: Dermatophagoides farinae (American house dust mite)
NCBI Taxomony ID: 6954
Biochemical name:NPC2 family; MD-2-related lipid recognition (ML) domain containing protein
Allergenicity:Of 51 sera from mite-allergic patients, 48 (94%) had IgE antibody to purified Der f 2, as measured by RIA. Positive skin reactions to Der f 2 were found in 11 out of 12 patients tested (LESSTHAN=10(-3) ug/ml) - Of 20 mite-allergic patients tested, 18 had IgE antibodies to purified Der f 2, as measured by RAST. Der f 2 induced basophil histamine release in all 16 patients tested: medline 87032478.
Allergenicity reference:PubMed:3770975
Route of allergen exposure:Airway
Created:2003-04-30 12:00:00
Last Updated:2023-11-09 13:24:40
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Submission Date:


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Der f 2.0101D10447BAA01239Q00855 (variant)1AHK 1AHM
Der f 2.0102D10448BAA01240 Q00855 
Der f 2.0103D10449BAA01241Q00855 (variant)1XWV
Der f 2.0104    
Der f 2.0105AY066008AAL47677Q8WQK5 
Der f 2.0106AJ862836CAI05848Q5TIW2 
Der f 2.0107AJ862837CAI05849Q5TIW1 
Der f 2.0108AJ862838CAI05850Q5TIW0 
Der f 2.0109DQ185511ABA39438Q3HWZ2 
Der f 2.0110    
Der f 2.0111    
Der f 2.0112AY283288AAP35073A1KXH0 
Der f 2.0113    
Der f 2.0114    
Der f 2.0115    
Der f 2.0116EF205129 A3F5F1 
Der f 2.0117