WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Alt a 1
Allergen source: Major taxonomic group: Fungi Ascomycota
Order: Pleosporales
Species: Alternaria alternata (Alternaria plant rot fungus)
NCBI Taxomony ID: 5599
MW(SDS-PAGE):16.4 kDa and 15.3 kDa band (30 kDa non-red)
Allergenicity:- Of 57 sera from A. alternaria-sensitive patients, 46 (82%) showed IgE binding to rAlt a 1 on immunoblot. - IgE binding (serumpool, n=34) to A. alternaria extract in ELISA could be inhibited up to 70% by purified native Alt a 1: medline 22659252. - 6 out of 7 patients gave positive skin reactions in response to Alt a 1: medline 22097420 - IgE epitope mapping: medline 22555437
Allergenicity reference:PubMed:8957113
Route of allergen exposure:Airway
Date Created:25-09-2009
Last Updated:2019-06-28 18:20:36
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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Alt a 1.0101U82633 U86752AAB40400 AAB47552P79085 
Alt a 1.0102AY568627AAS75297Q6Q128