WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Cas s 8
Allergen source: Major taxonomic group: Plantae Eudikotyledons
Order: Fagales
Species: Castanea sativa (Chestnut)
NCBI Taxomony ID: 21020
Biochemical name:Non-specific lipid transfer protein type 1
MW(SDS-PAGE):12-13 kDa (non-red), 9 kDa (red)
Allergenicity:Significant specific IgE levels to the puri?ed Cas s 8 were found in 7 (58%) of 12 allergic sera by means of ELISA and 6 (66%) of 9 patients by means of SPT.
Allergenicity reference:PubMed:10998016PubMed:16950291
Route of allergen exposure:Food
Created:2003-03-20 12:00:00
Last Updated:2019-07-20 08:41:21
Submitter Info:
Submission Date:


Posted: 02 Nov 2014

The N-terminal sequence listed in the publication by Diaz-Perales et al., 2000, and shown in the IUIS submission, does not match any other known sequence in NCBI at more than 57% identity. It is not clear if this sequence represents a natural chestnut LTP protein.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Cas s 8.0101