Allergen Details:
| Allergen name: | Art an 14 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Asterales Species: Artemisia annua (Sweet Wormwood) NCBI Taxomony ID: 35608 |
| Biochemical name: | Fructose bisphosphate aldolase |
| MW(SDS-PAGE): | 38 kDa |
| Allergenicity: | Sera from 20 pollen-allergic patients (allergic rhinitis and/or asthma) sensitized to Artemisia pollen (ImmunoCAP class >= 3 with A. vulgaris ImmunoCAP) were tested. Of those, 9 (45%) had IgE to recombinant Art an 14.0101, produced in E. coli. In a BAT assay with 3 Art an 14-sensitized patients, 2 of 3 reacted with rArt an 14.0101. In an IgE ELISA with a pool of Art an 14-sensitized sera, a high extent of IgE cross-reactivity with Art si 14 was shown. |
| Route of allergen exposure: | Airway |
| Created: | 2022-10-17 17:20:57 |
| Last Updated: | 2022-10-17 17:29:58 |
| Submitter Info: | |
| Name: | Ji-Fu Wei, Jin-Lyu Sun |
| Institution: | Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University; State Key Laboratory of Complex Severe and Rare Diseases, PUMCH, CAMS |
| City: | Nanjing, China and Beijing, China |
| Email: | weijifu@hotmail.com, sunjinlv@pumch.cn |
| Submission Date: | 2022-10-07 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Art an 14.0101 | ON706966 | WDR69748 |