Allergen Details
| Allergen name: | Zan b 2 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Sapindales Species: Zanthoxylum bungeanum (Sichuan pepper) NCBI Taxomony ID: 328401 |
| Biochemical name: | 11S globulin seed storage protein; legumin |
| MW(SDS-PAGE): | 50 kDa non reducingh, 22.3 kDa reducing |
| Allergenicity: | Six submects with claimed allergic responses to reduced glycinin of natural 11S albumin of Sichuan pepper were tested and found to have IgE binding to the reduced form of Sichuan pepper. The subjects had IgE binding to 2S albumin of these proteins by western blot and by ELISA Subjects had IgE binding to four proteins, two of similar MW and sequence and two others with IgE binding to compiled 2S albumins. |
| Route of allergen exposure: | Food |
| Created: | 2021-07-23 04:33:23 |
| Last Updated: | 2024-09-12 19:12:32 |
| Submitter Info: | |
| Name: | Tengchen Jun, Hong Li |
| Institution: | University of Science and Technology of China; Peking Union Medical College Hospital |
| City: | Hefei, China |
| Email: | jint@ustc.edu.cn; lihong1228sec@163.com |
| Submission Date: | 2021-06-09 |
Comments
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Zan b 2.0101 | MZ293069 | QYU76045 | A0A8G0QCJ5 | |
| Zan b 2.0102 | MZ293070 | QYU76046 | A0A8G0QCB5 | |
| Zan b 2.02 | MZ293068 | QYU76044 | A0A8G0QCW4 | |
| Zan b 2.03 | MZ333534 | QYS16039 | A0A8G0KJM2 |