Allergen Details
| Allergen name: | Can s 5 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Rosales Species: Cannabis sativa (Indian hemp) NCBI Taxomony ID: 3483 |
| Biochemical name: | Pathogenesis-related protein PR-10, Bet v 1-related protein |
| Molecular mass: | 17.7 kDa |
| Allergenicity: | 35 of 45 subjects with allergy to Cannabis (n=25) and/or birch pollen (n=20) were positive in IgE binding tested by cytometric bead assay using recominant protein as the target. Also, 8 of 8 tested by Mast Cell Activation were positive using the same recombinant protein. Subjects also reportedly were positive in contact testing. |
| Allergenicity reference: | PubMed:33607338 |
| Route of allergen exposure: | Airway |
| Created: | 2021-01-24 18:32:46 |
| Last Updated: | 2024-10-04 16:09:25 |
| Submitter Info: | |
| Name: | Hans-Peter Rihs |
| Institution: | Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Institute of the Ruhr-University Bochum |
| City: | Bochum, Germany |
| Email: | rihs@ipa-dguv.de |
| Submission Date: | 2020-11-27 |
Comments
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Can s 5.0101 | JN6792251 | AFN42528 | I6XT51 |