Allergen Details
Allergen name: | Cari p 2 |
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Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Brassicales Species: Carica papaya (Papaya) NCBI Taxomony ID: 3649 |
Biochemical name: | Chymopapain; member of the papain-like cysteine protease (petidase C1) family |
MW(SDS-PAGE): | 28 kDa |
Allergenicity: | Ten subjects allergic to ingestion of papaya fruit were tested with recombinant protein produced by a cDNA clone from EMBL accession X97789.1, Taylor et al., protein is in GEPEPT as CAA66378.1. The recombinant protein was characterized also with LC-MSMS on the N-terminus. The rProtein was used for SPT in patients with 3 of 3 testing positive. Also used in a humanized rat basophil leukemia assay and 6 sera were positive. |
Route of allergen exposure: | Food |
Created: | 2020-11-05 21:37:00 |
Last Updated: | 2022-05-10 18:43:00 |
Submitter Info: | |
Name: | Gaurab Sircar; Moumita Bhowmik |
Institution: | Visva-Bharati University, Dept. of Botany; Bose Institute Div. of Plant Biology |
City: | Santiniketan, India; Kolkata, India |
Email: | sircar.gaurab129@gmail.com; bhowmikmoumita89@gmail.com |
Submission Date: | 2020-09-29 |
Comments
Table of Isoallergens
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Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
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Cari p 2.0101 | X97789. | CAA66378 | P14080 |