Allergen Details
| Allergen name: | Tyr p 20 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Arthropoda Order: Sarcoptiformes Species: Tyrophagus putrescentiae (Storage mite) NCBI Taxomony ID: 59818 |
| Biochemical name: | Arginine kinase |
| MW(SDS-PAGE): | 40 kDa |
| Allergenicity: | 298 subjects attending the Taichung Veterans General Hospital were recruited with at least asthma, rhinitis, atopic dermatitis or eczema. They were tested by SPT and ELISA to recombinant Tyr p 20.0101, which had been cloned by PCR. Indirect basophil activation was tested. 51 of 298 were positive for IgE binding by ELISA, 45 of 106 were positive by SPT and 25 of 30 positive by basophil activation. |
| Allergenicity reference: | PubMed:32887361 |
| Route of allergen exposure: | Airway |
| Created: | 2020-09-08 22:39:58 |
| Last Updated: | 2022-04-13 16:29:32 |
| Submitter Info: | |
| Name: | En-Chih Liao |
| Institution: | Mackay Medical College |
| City: | Taipei City, Taiwan |
| Email: | enchih@mmc.edu.tw |
| Submission Date: | 2020-08-26 |
Comments
The sequence of Tyr p 20.0201 was updated on 2022-10-11. The originally submitted sequence had an N-terminal extension due to an incorrectly identified start codon.
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Tyr p 20.0101 | MT900252 | QOI58528 | A0A868BHP5 | |
| Tyr p 20.0201 | MZ824392 | UXW65972 |
cDNA sequence and predicted AA sequence in submission. Not for public view until published. High identity to Der p 20, Blo t 20. two peptides of recombinant protein determined by LC-MSMS.