Allergen Details
| Allergen name: | Bos d 13 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Chordata Order: Cetartiodactyla Species: Bos domesticus (Bos taurus) (Domestic cattle) NCBI Taxomony ID: 9913 |
| Biochemical name: | Myosin light chain |
| MW(SDS-PAGE): | 21 kDa |
| Allergenicity: | Thirty-one allergic patients sensitized to beef (ImmunoCAP) were tested, of which 16 reported allergic symptoms after consumption of red meat. Nine subjects showed IgE binding to a 20 kDa protein in IgE immunoblots with cooked beef extract. When tested by ELISA with recombinant Bos d 13, 8/9 subjects (5 allergic and 3 sensitized) and 5/9 subjects (4 allergic and 1 sensitized) had IgE to Bos d 13.0101 and Bos d 13.0201, respectively. |
| Allergenicity reference: | PubMed:37173826 |
| Route of allergen exposure: | Food |
| Created: | 2020-03-25 17:24:23 |
| Last Updated: | 2023-05-15 15:24:30 |
| Submitter Info: | |
| Name: | Ines Swoboda; Patricia Roman-Carrasco |
| Institution: | FH Campus Wien |
| City: | Vienna, Austria |
| Email: | ines.swoboda@fh-campuswien.ac.at; patricia.roman-carrasco@outlook.com |
| Submission Date: | 2019-10-12 |
Comments
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Bos d 13.0101 | NM_001079578 BC126716 | AAI26717 | A0JNJ5 | |
| Bos d 13.0201 | NM_001076501.2 | NP_001069969 | P85100 |