Allergen Table
| Taxonomic group | Order | Species | Common name | Allergen ID | Allergen Name | Biochemical Names | MW (SDS-PAGE) | Obsolete Names | Allergenicity | Allergenicity Ref | Route of Exposure | Date Added | Date Updated |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Plantae Eudikotyledons | Fabales | Acacia farnesiana (Vachellia farnesiana) | Needle bush | 837 | Aca f 1 | Ole e 1-like protein | 17 kDa | SPT positive in 21 of 45 subjects with inhalation allergy 23 of 45 with IgE binding in reducing immunoblot | 2 | 2015-07-17 12:00:00 | 2024-06-28 17:54:38 | ||
| Plantae Eudikotyledons | Fabales | Acacia farnesiana (Vachellia farnesiana) | Needle bush | 802 | Aca f 2 | Profilin | 14.3 kDa | 2 | 2014-08-18 12:00:00 | 2025-08-25 17:00:23 | |||
| Animalia Arthropoda | Sarcoptiformes | Acarus siro | Flour mite | 1189 | Aca s 2 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 14 kDa | See isoallergens | 2 | 2026-05-21 16:48:09 | 2026-05-21 17:51:24 | ||
| Animalia Arthropoda | Sarcoptiformes | Acarus siro | Flour mite | 1 | Aca s 13 | Cytosolic fatty acid-binding protein | 15 kDa | 3 out of 13 (23%) A. siro RAST-positive patients showed strong IgE binding to rAca s 13 on immunoblot | 10474032 | 2 | 2003-04-22 12:00:00 | 2023-11-09 14:06:40 | |
| Plantae Eudikotyledons | Ericales | Actinidia chinensis | Gold kiwi fruit | 3 | Act c 5 | Kiwellin | 28 kDa | Sera from six individual kiwi-allergic subjects (with positive SPT and IgE CAP) showed IgE binding to purified kiwellin from both green kiwi fruit and gold kiwi fruit on immunoblot. | 18442249 | 1 | 2008-07-08 12:00:00 | 2019-06-28 08:09:27 | |
| Plantae Eudikotyledons | Ericales | Actinidia chinensis | Gold kiwi fruit | 4 | Act c 8 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 17 kDa | IgE prevalence: ELISA: n=41, prevalence: 54%; immunoblot: n=6, prevalence: 83% | 18925615 | 1 | 2007-09-25 12:00:00 | 2024-06-28 18:04:39 | |
| Plantae Eudikotyledons | Ericales | Actinidia chinensis | Gold kiwi fruit | 2 | Act c 10 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | 10/30 kiwi allergic patients had IgE to Act c 10.0101 in their sera and recated positive in SPTs with the purified natural protein. | 22114713 | 1 | 2008-07-08 12:00:00 | 2025-04-10 17:29:33 | |
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 5 | Act d 1 | Cysteine protease (actinidin) | 30 kDa | Act c 1 | All 30 sera of kiwi-allergic patients tested, showed IgE binding to a 30 kD protein on immunoblot of kiwi extract (medline 96426244). This protein was later identified as Act c 1. | 9564807 | 1 | 2007-02-09 12:00:00 | 2020-05-13 17:56:21 |
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 8 | Act d 2 | Thaumatin-like protein | 24 kDa | Act c 2 | All 7 sera of kiwi-allergic patients tested, showed IgE binding to a 24 kDa protein on immunoblot of kiwi extract. | 12417892 | 1 | 2007-02-09 12:00:00 | 2019-06-28 06:30:32 |
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 9 | Act d 3 | 40 kDa | 18205857 | 1 | 2007-02-08 12:00:00 | 2020-05-13 18:00:07 | |||
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 10 | Act d 4 | Phytocystatin | 11 kDa | 1 | 2007-02-18 12:00:00 | 2019-06-28 08:21:11 | |||
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 11 | Act d 5 | Kiwellin | 28 kDa | Sera from two patients reporting significant symptoms upon ingestion of kiwi showed IgE binding to kiwi fruit extract and the purified 28 kDa kiwellin on Western blot. | 16328735 26146952 18442249 | 1 | 2007-02-18 12:00:00 | 2020-05-13 18:03:32 | |
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 12 | Act d 6 | Pectin methylesterase inhibitor | 18 kDa | IgE prevalence: 72% of 50 kiwi allergic patients | 10880981 | 1 | 2007-12-18 12:00:00 | 2020-08-28 01:45:22 | |
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 13 | Act d 7 | Pectin methylesterase | 50 kDa | IgE prevalence: 32% of 50 kiwi allergic patients in immunoblot | 1 | 2007-12-18 12:00:00 | 2019-06-28 07:24:00 | ||
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 14 | Act d 8 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 17 kDa | IgE prevalence: 60% of 10 kiwi allergic patients in ELISA; 100% of 6 kiwi allergic patients in immunoblot. | 1 | 2007-12-18 12:00:00 | 2019-06-28 07:24:37 | ||
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 15 | Act d 9 | Profilin | 14 kDa | 6/30 kiwi allergic individuals tested positive in CAP. | 20061012 | 1 | 2008-07-08 12:00:00 | 2019-06-28 07:46:25 | |
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 6 | Act d 10 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | 1 | 2008-07-08 12:00:00 | 2025-04-10 17:46:21 | |||
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 7 | Act d 11 | Major latex protein/ripening-related protein (MLP/RRP), Bet v 1 family member | 17 kDa | 22/91 (24.2%) kiwi allergic patients had IgE to the natural purified Act d 11 when sera were tested by the ISAC microarray system. 18/91 (22%) of kiwi allergic patients reacted positively in SPT when tested with natural purified Act d 11. | 21309790 | 1 | 2009-02-23 12:00:00 | 2020-05-13 18:12:59 | |
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 788 | Act d 12 | Cupin, 11S globulin seed storage protein | 50,207.304 Da (mass spectrometry of Act d 12.0101) | Sera from 39 of 55 kiwifruit allergic individuals had IgE that reacted with the purified natural Act d 12 in immunobolots and ELISA. Basophil activation tests of 3 of 4 patients with the purified nAct d 12 were positive. SPTs of 4 of 4 patients with the purified nAct d 12 were positive. | 25041438, 24990823 | 1 | 2014-02-14 12:00:00 | 2024-10-10 10:51:48 | |
| Plantae Eudikotyledons | Ericales | Actinidia deliciosa | Green kiwi fruit | 789 | Act d 13 | 2S albumin | 11,359,6 Da (mass spectrometry) | Sera from 10 of 55 kiwifruit allergic individuals had IgE that reacted with the purified natural Act d 13 in immunobolots and ELISA. A basophil activation test of 1 patient with the purified nAct d 13 was positive. A SPT of 1 patient with the purified nAct d 13 was positive. | 25041438, 24990823 | 1 | 2016-02-24 12:00:00 | 2024-10-10 11:26:10 | |
| Animalia Arthropoda | Diptera | Aedes aegypti | Yellow fever mosquito | 16 | Aed a 1 | Apyrase | 68 kDa | - rAed a 1 bound to human IgE, as detected by ELISA, Nine out of 31 (29%) of the subjects with positive immediate bite tests also had a positive rAed a 1 immediate skin reaction. Six of 33 (18%) of the subjects with positive delayed bite tests also had a positive rAed a 1 delayed skin reaction. - 43% of 28 mosquito bite test-positive subjects had a positive skin test to rAed a 1: medline 21203342 | 11717185 | 4 | 2003-05-20 12:00:00 | 2019-07-22 19:56:33 | |
| Animalia Arthropoda | Diptera | Aedes aegypti | Yellow fever mosquito | 17 | Aed a 2 | Salivary odorant binding protein D7 | 37 kDa | Of 28 mosquito bite test-positive subjects tested, 3 (11%) had a positive skin test to rAed a 2 | 11307029 | 4 | 2003-05-20 12:00:00 | 2022-09-19 15:42:49 | |
| Animalia Arthropoda | Diptera | Aedes aegypti | Yellow fever mosquito | 18 | Aed a 3 | Uncharacterized 30 kDa salivary protein | 30 kDa | Of 28 mosquito-bite test-positive subjects, 9 (32%) had a positive skin reaction to rAed a 3. | 11307029 | 4 | 2003-05-20 12:00:00 | 2022-09-19 15:33:36 | |
| Animalia Arthropoda | Diptera | Aedes aegypti | Yellow fever mosquito | 856 | Aed a 4 | alpha-glucosidase | 67 kDa | Subjects were allergic to mosquito bites. 13 of 13 were positive to challenge bites of mosquito, Aedes aegypti, 18 controls were negative. 6 of 13 subjects were IgE binding positive to recombinant Aed a 4 by ELISA, 18 controls were negative. ELISA and ELISA inhibition were performed with native (extract of head and thorax) and recombinant Aed a 4 produced in baculovirus insect cell line. | 17620829 18220995 25661054 | 4 | 2016-03-13 12:00:00 | 2019-07-20 18:26:53 | |
| Animalia Arthropoda | Diptera | Aedes aegypti | Yellow fever mosquito | 857 | Aed a 5 | Sarcoplasmic Calcium binding protein | 28.5 kDa | Case history of mosquito allergy (bites and/or inhalation of insect parts) from subjects living in the Caribbean island of Martinique with asthma and/or rhinitis and specific IgE to mosquito extract. Proteins of defatted, freeze dried mosquitoes, with proteins separated on 2D gels and immunoblotted with six individual sera Abstract presented at EAACI Barcelona, 2015. IgE binding spots were identified by mass LC/MS-MS of trypsinized gel spots. Sarcoplasmic Ca+ binding protein bound IgE from 4 of 6 subjects. | 28235135 | 2 | 2015-12-30 12:00:00 | 2022-09-19 15:36:18 | |
| Animalia Arthropoda | Diptera | Aedes aegypti | Yellow fever mosquito | 858 | Aed a 6 | Porin3 | 30.7 kDa | Case history of mosquito allergy (bites and/or inhalation of insect parts) from subjects living in the Caribbean island of Martinique with asthma and/or rhinitis and specific IgE to mosquito extract. Proteins of defatted, freeze dried mosquitoes, with proteins separated on 2D gels and immunoblotted with six individual sera Abstract presented at EAACI Barcelona, 2015. IgE binding spots were identified by mass LC/MS-MS of trypsinized gel spots. Porin3 bound IgE from 2 of 6 subjects. | 2 | 2015-12-30 12:00:00 | 2019-07-22 17:21:30 | ||
| Animalia Arthropoda | Diptera | Aedes aegypti | Yellow fever mosquito | 859 | Aed a 7 | Uncharacterized protein | Case history of mosquito allergy (bites and/or inhalation of insect parts) from subjects living in the Caribbean island of Martinique with asthma and/or rhinitis and specific IgE to mosquito extract. Proteins of defatted, freeze dried mosquitoes, with proteins separated on 2D gels and immunoblotted with six individual sera Abstract presented at EAACI Barcelona, 2015. IgE binding spots were identified by mass LC/MS-MS of trypsinized gel spots. Unknown salivary protein bound IgE from 3 of 6 subjects. | 28235135 | 4 | 2015-12-30 12:00:00 | 2022-09-19 15:39:14 | ||
| Animalia Arthropoda | Diptera | Aedes aegypti | Yellow fever mosquito | 860 | Aed a 8 | Heat Shock cognate protein-70 | Case history of mosquito allergy (bites and/or inhalation of insect parts) from subjects living in the Caribbean island of Martinique with asthma and/or rhinitis and specific IgE to mosquito extract. Proteins of defatted, freeze dried mosquitoes, with proteins separated on 2D gels and immunoblotted with six individual sera Abstract presented at EAACI Barcelona, 2015. IgE binding spots were identified by mass LC/MS-MS of trypsinized gel spots. Heat Shock Protein protein bound IgE from 5 of 6 subjects. | 28235135 | 4 | 2015-12-30 12:00:00 | 2019-06-28 18:00:29 | ||
| Animalia Arthropoda | Diptera | Aedes aegypti | Yellow fever mosquito | 835 | Aed a 10 | Tropomyosin | 32 kDa | 9 of 15 subjects allergic to Aedes aegypti had IgE binding to this tropomyosin | 28235135 | 2 | 2015-07-13 12:00:00 | 2019-07-20 18:13:47 | |
| Animalia Arthropoda | Diptera | Aedes aegypti | Yellow fever mosquito | 867 | Aed a 11 | Lysosomal aspartic protease | 15 subjects with airway and/or dermal allergic reactions upon exposure to mosquito bites or Case history of mosquito allergy (bites and/or inhalation of insect parts) from subjects living in the Caribbean island of Martinique with asthma and/or rhinitis and specific IgE to mosquito extract. Proteins of defatted, freeze dried mosquitoes, with proteins separated on 2D gels and immunoblotted with six individual sera Abstract presented at EAACI Barcelona, 2015. IgE binding spots were identified by mass LC/MS-MS of trypsinized gel spots. Lysosomal aspartic protease bound IgE from 3 of 6 subjects. | 28235135 | 4 | 2016-03-02 12:00:00 | 2019-06-28 17:43:43 | ||
| Animalia Arthropoda | Diptera | Aedes aegypti | Yellow fever mosquito | 1095 | Aed a 12 | Triosphosphate isomerase | 23 kDa | Seven of 19 subjects with allergy and rhinitis to house dust mite and/or cockroach or shrimp were tested for by SPT to whole body extract of Aedes aegypti mosquito. When their sera were tested by ELISA to recombinant protein, with the seven having positive IgE binding by ELISA out of the 19. Five negative controls did not have binding to this ELISA. This data suggests IgE sensitization and possible allergy. Exposure may be by injection or may be by inhalation | 4 | 2022-04-17 20:50:13 | 2022-05-08 23:41:40 | ||
| Animalia Arthropoda | Diptera | Aedes albopictus | Asian tiger mosquito | 939 | Aed al 2 | D7 like salivary odorant binding protein | 33 kDa | 10 of 15 subjects with immediate or delayed skin reactivity to bites by Asian Tiger mosquito were positive in IgE binding to this protein by western blot. | 32099589 | 4 | 2018-10-09 21:02:05 | 2021-11-30 20:50:17 | |
| Animalia Arthropoda | Diptera | Aedes albopictus | Asian tiger mosquito | 938 | Aed al 3 | 30 kDa Salivary protein | 30 kDa | 32099589 | 4 | 2018-10-09 19:53:47 | 2021-11-30 21:10:04 | ||
| Animalia Arthropoda | Diptera | Aedes albopictus | Asian tiger mosquito | 1117 | Aed al 13 | Antigen 5-3 | 27 kDa | Patients were selected based on abnormal reactions to mosquito bites and serum IgE to salivary gland extract as measured by ELISA. Of 18 tested sera, 16 (89%) had IgE to recombinant Aed al 13, as determined by ELISA. | 37965096 | 4 | 2022-09-19 16:36:17 | 2024-09-18 17:44:50 | |
| Animalia Arthropoda | Diptera | Aedes albopictus | Asian tiger mosquito | 1118 | Aed al 14 | Salivary antigen LIPS-2 / 34k-2 | 34 kDa (SEC) | Patients were selected based on abnormal reactions to mosquito bites and serum IgE to salivary gland extract as measured by ELISA. Of 18 tested sera, 14 (78%) had IgE to recombinant Aed al 14, as determined by ELISA. | 37965096 | 4 | 2022-09-19 16:47:46 | 2024-09-18 17:47:05 | |
| Plantae Eudikotyledons | Sapindales | Aesculus hippocastanum | Horse chestnut | 1012 | Aes h 1 | Defensin-like protein | 5.8 kDa | Thirty mugwort pollen-sensitized patients sensitized to horse chestnut seeds as determined by prick-to-prick test were included in the study. Four of those showed allergic reactions upon contact with horse chestnuts. All 30 sera reacted to rAes h 1 and 29 to nAes h 1 in an IgE-ELISA. Inhibition ELISA showed cross-reactivity with Art v 1 from mugwort pollen and suggested Art v 1 to be the initial sensitizer. | 10.1111/all.16335 | 3 | 2020-03-25 20:54:26 | 2024-09-24 11:34:08 | |
| Plantae Eudikotyledons | Fagales | Alnus glutinosa | Alder | 19 | Aln g 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 18 kDa | In immunoblot analysis, all 9 tree pollen-allergic patients tested showed IgE binding to both natural Aln g 1 and recombinant Aln g 1 | 1460197 | 2 | 2003-03-13 12:00:00 | 2019-06-28 18:15:54 | |
| Plantae Eudikotyledons | Fagales | Alnus glutinosa | Alder | 20 | Aln g 4 | Polcalcin | 6-7 kDa | - rAln g 4 reacted with serum IgE from 18% of pollen-allergic patients tested(n = 122). Patients were allergic to: olive (n = 50), grass (n = 20), birch (n = 12), mugwort pollen (n = 20), and maize (n = 20). - Purified rAln g 4 elicited dose-dependent basophil histamine release in 3 patients tested and immediate type skin reactions in 3 patients tested. | 9862740 | 2 | 2003-03-13 12:00:00 | 2019-06-28 18:16:50 | |
| Fungi Ascomycota | Pleosporales | Alternaria alternata | Alternaria plant rot fungus | 21 | Alt a 1 | 16.4 kDa and 15.3 kDa band (30 kDa non-red) | - Of 57 sera from A. alternaria-sensitive patients, 46 (82%) showed IgE binding to rAlt a 1 on immunoblot. - IgE binding (serumpool, n=34) to A. alternaria extract in ELISA could be inhibited up to 70% by purified native Alt a 1: medline 22659252. - 6 out of 7 patients gave positive skin reactions in response to Alt a 1: medline 22097420 - IgE epitope mapping: medline 22555437 | 8957113 | 2 | 2009-09-25 12:00:00 | 2019-06-28 18:20:36 | ||
| Fungi Ascomycota | Pleosporales | Alternaria alternata | Alternaria plant rot fungus | 25 | Alt a 3 | Heat shock protein 70 | rAlt a 3 was recognized on immunoblot by 5% of the sera from A.Alternaria-sensitive patients review: medline 22097420 | 9693275 | 2 | 2009-09-25 12:00:00 | 2019-06-28 18:24:27 | ||
| Fungi Ascomycota | Pleosporales | Alternaria alternata | Alternaria plant rot fungus | 26 | Alt a 4 | Disulfide isomerase | 57 kDa | Of 98 A.alternata-sensitized patients (positive immunoblot of A.alternara extract), 42% showed IgE binding to Alt a 4 on immunoblot. | 7898496 | 2 | 2009-09-25 12:00:00 | 2019-06-28 18:32:00 | |
| Fungi Ascomycota | Pleosporales | Alternaria alternata | Alternaria plant rot fungus | 27 | Alt a 5 | Ribosomal protein P2 | 11 kDa | Alt a 6 | - 6 out of 43 sera (14%) from A.alternaria-sensitive patients showed IgE binding to rAlt a 6 on immunoblot. - Of 98 A.alternata-sensitized patients (positive immunoblot of A.alternata extract), 8% showed IgE binding to Alt a 6 on immunoblot: medline 95206305 and 95337840 | 9693275 | 2 | 2009-09-25 12:00:00 | 2019-06-28 18:25:41 |
| Fungi Ascomycota | Pleosporales | Alternaria alternata | Alternaria plant rot fungus | 28 | Alt a 6 | Enolase | 45 kDa | Alt a 5, Alt a 11 | - 2 out of 7 A.alternaria-sensitive patients gave positive skin reactions in response to Alt a 11. - Of 23 A.alternaria-sensitized patients tested, 22% showed serum IgE binding to purified Alt a 11 on immunoblot: medline 20534817. | 12102004 | 2 | 2009-09-25 12:00:00 | 2025-08-25 16:30:20 |
| Fungi Ascomycota | Pleosporales | Alternaria alternata | Alternaria plant rot fungus | 29 | Alt a 7 | YCP4 protein | 22 kDa | Of 98 A.alternata-sensitize patients (positive immunoblot of A.alternata extract), 7% showed IgE binding to Alt a 7 on immunoblot (see also medline 95337840). | 7898496 | 2 | 2009-09-25 12:00:00 | 2019-06-28 18:26:50 | |
| Fungi Ascomycota | Pleosporales | Alternaria alternata | Alternaria plant rot fungus | 30 | Alt a 8 | Mannitol dehydrogenase | 29 kDa | In IgE-ELISA and immunoblots, recombinant Alt a 8 was recognized by 41% of A. alternata-allergic patients. In vivo immunoreactivity of the allergen was verified by skin prick testing. | 17177674 | 2 | 2009-09-25 12:00:00 | 2019-06-28 18:27:23 | |
| Fungi Ascomycota | Pleosporales | Alternaria alternata | Alternaria plant rot fungus | 22 | Alt a 10 | Aldehyde dehydrogenase | 53 kDa | Of 98 A.alternata-sensitized patients (positive immunoblot of A.alternata extract), 2% showed IgE binding to Alt a 10 on immunoblot (see also medline 95337840). | 7898496 | 2 | 2009-09-25 12:00:00 | 2019-06-28 18:27:55 | |
| Fungi Ascomycota | Pleosporales | Alternaria alternata | Alternaria plant rot fungus | 23 | Alt a 12 | Acid ribosomal protein P1 | 11 kDa | 2 | 2009-09-25 12:00:00 | 2019-06-28 18:28:18 | |||
| Fungi Ascomycota | Pleosporales | Alternaria alternata | Alternaria plant rot fungus | 24 | Alt a 13 | Glutathione-S-transferase | 26 kDa | 2 | 2009-09-25 12:00:00 | 2019-06-28 18:28:42 | |||
| Fungi Ascomycota | Pleosporales | Alternaria alternata | Alternaria plant rot fungus | 790 | Alt a 14 | Manganese superoxide dismutase | 24 kDa (reducing) | 21255138 | 2 | 2014-02-19 12:00:00 | 2019-06-28 18:29:24 | ||
| Fungi Ascomycota | Pleosporales | Alternaria alternata | Alternaria plant rot fungus | 820 | Alt a 15 | Serine protease | 58 kDa | Three of 53 mold-sensitized subjects had IgE+ binding in reducing immunoblot presented at EAACI as poster in Milan, 2013. | 2 | 2014-11-11 12:00:00 | 2019-06-28 18:30:31 | ||
| Plantae Eudikotyledons | Caryophyllales | Amaranthus retroflexus | Redroot pigweed | 836 | Ama r 1 | Ole e 1- like protein | 18 kDa | 26925110 | 2 | 2015-07-17 12:00:00 | 2019-06-28 18:48:58 | ||
| Plantae Eudikotyledons | Caryophyllales | Amaranthus retroflexus | Redroot pigweed | 31 | Ama r 2 | Profilin | 14 kDa | 5/19 (25%) patients with seasonal rhinoconjuctivitis and positive SPT with A. retroflexus pollen extract showed IgE binding to a 14 kDa band in A. retroflexus pollen extract, which could be inhibited with the reccombinant profilins Cuc m 2 and Che a 2. | 21430432 | 2 | 2009-10-15 12:00:00 | 2020-05-13 21:05:04 | |
| Plantae Eudikotyledons | Asterales | Ambrosia artemisiifolia | Short ragweed | 32 | Amb a 1 | Pectate lyase | 38 kDa | antigen E, antigen K, Amb a 2 (now isoallergen Amb a 1.05) | 97% of 65 patients tested showed serum IgE binding to Amb a 1 in RAST - 95% of ragweed allergic patients showed IgE binding to Amb a 1 in RIA, and had positive skin prick tests to Amb a 1. | 81221 | 2 | 2003-04-10 12:00:00 | 2025-08-25 16:31:23 |
| Plantae Eudikotyledons | Asterales | Ambrosia artemisiifolia | Short ragweed | 34 | Amb a 2 | renamed to Amb a 1.05; number not available for future submissions | 2 | 2003-04-10 12:00:00 | 2025-08-25 16:32:03 | ||||
| Plantae Eudikotyledons | Asterales | Ambrosia artemisiifolia | Short ragweed | 35 | Amb a 3 | Plastocyanine | 11 kDa | Ra3 | 51% of 65 patients with ragweed hay fever tested show IgE binding to Amb a 3 in RAST | 81221 | 2 | 2003-04-10 12:00:00 | 2019-06-28 19:01:35 |
| Plantae Eudikotyledons | Asterales | Ambrosia artemisiifolia | Short ragweed | 686 | Amb a 4 | Defensin-like protein linked to polyproline-rich region, homologue of Art v 1 | 28-30 kDa | Patients allergic to mugwort and ragweed that were SPT positive, RAST positive gave sera. ELISA and ELISA inhibition were used to demonstrate IgE binding | 20576600 | 2 | 2016-04-04 12:00:00 | 2025-08-25 17:01:43 | |
| Plantae Eudikotyledons | Asterales | Ambrosia artemisiifolia | Short ragweed | 36 | Amb a 5 | 5 kDa | Ra5 | 18 selected ragweed-allergic patients showed serum IgE binding to native and rAmb a 5 in DARIA; histamine release from basophils from 2 allergic patients induced by both native and rAmb a 5 - 17% of 65 pateints with ragweed hay fever showed IgE binding to Amb a 5 in RAST. | 7685794; 1390654 | 2 | 2003-04-10 12:00:00 | 2020-05-13 21:15:48 | |
| Plantae Eudikotyledons | Asterales | Ambrosia artemisiifolia | Short ragweed | 37 | Amb a 6 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | Ra6 | Among 101 ragweed-sensitive patients, 21% had serum IgE antibodies against purified Amb a 6. Among 32 highly ragweed-allergic patients tested, 8 showed positive skin reactions (25%). | 6863927 | 2 | 2003-04-10 12:00:00 | 2025-04-10 18:29:12 |
| Plantae Eudikotyledons | Asterales | Ambrosia artemisiifolia | Short ragweed | 38 | Amb a 7 | Plastocyanin | 12 kDa | Ra7 | About 15-20% of ragweed-allergic patients were found to have IgE against Amb a 7. Roebber, M., and D.G. Marsh. 1991. Isolation and characterization of allergen Amb a VII from short ragweed pollen. J. Allergy Clin. Immunol. 87:324 (abstract) | 2 | 2003-04-14 12:00:00 | 2019-06-28 19:36:01 | |
| Plantae Eudikotyledons | Asterales | Ambrosia artemisiifolia | Short ragweed | 39 | Amb a 8 | Profilin | 14 kDa | Published 2008. Mugwort and ragweed allergic patients (pool of 46) used to screen cDNA library with patients from Italy and Austria. Selected clones were expressed and tested for cross-reactivity using sera from 5 subjects. Proteins were characterized for MW and structure. | 18588553 | 2 | 2006-11-03 12:00:00 | 2019-06-28 19:37:35 | |
| Plantae Eudikotyledons | Asterales | Ambrosia artemisiifolia | Short ragweed | 40 | Amb a 9 | Polcalcin | 9 kDa | A pool of 46 subjects with allergies to ragweed from Italy and Austria were used to select 2 positive IgE binding clones that are polcalcins. Five individual subects were used for IgE binding, inhibition and basophil activity tests. | 18588553 | 2 | 2006-11-03 12:00:00 | 2019-06-28 19:38:23 | |
| Plantae Eudikotyledons | Asterales | Ambrosia artemisiifolia | Short ragweed | 33 | Amb a 10 | Polcalcin-like protein (4 EF-hands) | 17 kDa | A few Italian ragweed sensitive subjects had IgE binding to the protein expressed from Amb a 10 clone. Basophil activity was low, but measurable. | 18588553 | 2 | 2006-11-03 12:00:00 | 2020-05-13 21:27:20 | |
| Plantae Eudikotyledons | Asterales | Ambrosia artemisiifolia | Short ragweed | 784 | Amb a 11 | Papain-like cysteine protease | 37 kDa (natural purified mature protein), 52 kDa (natural purified zymogen) | Sera from 38 of 70 short ragweed pollen allergic individuals contained IgE that reacted with nAmb a 11 on 2D immunoblots. | 25865353 | 2 | 2013-11-20 12:00:00 | 2026-05-28 17:36:43 | |
| Plantae Eudikotyledons | Asterales | Ambrosia artemisiifolia | Short ragweed | 904 | Amb a 12 | Enolase | 48 kDa | Sera from 27 of 41 subjects with inhalation allergy and sensitized to Ragweed proteins, had IgE binding to Enolase in western blot and dot blot | 2 | 2017-10-12 14:39:24 | 2019-06-28 19:40:08 | ||
| Plantae Eudikotyledons | Asterales | Ambrosia psilostachya | Western ragweed | 41 | Amb p 5 | 5 kDa | Amb p V-A | Histamine release from basophils from 2 ragweed-allergic patients tested, induced by purified Amb p 5. Strong inhibition (80-90%)of IgE binding to Amb a 5 by Amb p 5, in 6 Amb a 5-allergic patients tested | 7511632 | 2 | 2003-04-14 12:00:00 | 2020-05-13 21:31:27 | |
| Plantae Eudikotyledons | Asterales | Ambrosia trifida | Giant ragweed | 42 | Amb t 5 | 5 kDa | Ra5G | Of 200 ragweed-sensitive patients, 10 patients (5%) had a positive skin test to purified Amb t 5. | 1606135 | 2 | 2003-04-14 12:00:00 | 2019-06-28 19:43:51 | |
| Plantae Eudikotyledons | Asterales | Ambrosia trifida | Giant ragweed | 1043 | Amb t 8 | Profilin | 14 kDa | Recombinant protein cloned and expressed, used as an IgE binding target. 85 of 198 subjects with airway allergy to ragweed pollen were positive in ELISA to this protein. Aldo one subject had 50% activation in 3 samples of one subject to this protein | 2 | 2020-12-04 21:06:39 | 2021-08-05 18:51:49 | ||
| Plantae Eudikotyledons | Asterales | Ambrosia trifida | Giant ragweed | 1066 | Amb t 13 | superoxide dismutase | 17 kDa | 90 people with apparent claimed allergy to pollen of giant ragweed in China were tested and 5 had IgE binding by ELISA to the recombinant protein | 2 | 2021-08-03 01:31:49 | 2021-08-03 17:00:33 | ||
| Plantae Eudikotyledons | Asterales | Ambrosia trifida | Giant ragweed | 1154 | Amb t 18 | Triosephosphate isomerase | 26 kDa | Sera from 37 pollen-allergic patients with allergic symptoms in late summer (rhinitis, conjunctivitis and/or asthma) and sIgE to Ambrosia pollen (ImmunoCAP) were tested. Of those, 13 sera (35%) had IgE to recombinant Amb t 18.0101 produced in E. coli. All 4 tested ELISA-positive sera reacted to the natural and recombinant allergen in an IgE-immunoblot. In an indirect BAT, basophils sensitized with 4 ELISA-positive sera were activated after stimulation with rAmb t 18.0101. In an inhibition ELISA with a pool of ELISA-positive sera, preincubation with rAmb t 18.0101 inhibited IgE binding to Ambrosia trifida pollen extract by 18%. | 41082203 | 2 | 2024-08-14 12:06:57 | 2025-10-15 15:45:34 | |
| Plantae Eudikotyledons | Sapindales | Anacardium occidentale | Cashew | 45 | Ana o 1 | Vicilin-like protein | 50 kDa | Of 20 patients with cashew allergy, 10 (50%) bound to rAna o 1 on immunoblot. | 12110836 | 1 | 2003-08-08 12:00:00 | 2019-07-03 18:36:33 | |
| Plantae Eudikotyledons | Sapindales | Anacardium occidentale | Cashew | 46 | Ana o 2 | Legumin-like protein | 55 kDa | By IgE immunoblotting, 13 of 21 sera (62%) from cashew-allergic patients were reactive. Immunoblot inhibition data showed that the native Ana o 2 constitutes a major band at approximately 33 kD and a minor band at approximately 53 kD. | 14555856 | 1 | 2004-10-17 12:00:00 | 2019-07-03 18:37:00 | |
| Plantae Eudikotyledons | Sapindales | Anacardium occidentale | Cashew | 47 | Ana o 3 | 2S albumin | 14 kDa | Immunoblot analysis showed 21 (81%) of 26 sera from patients with cashew allergy were reactive. Three native Ana o 3 large-subunit isoforms with molecular weights ranging from approximately 6 to 10 kd were identified. | 15940148 | 1 | 2004-04-18 12:00:00 | 2019-07-03 18:37:18 | |
| Plantae Liliopsida (monocots) | Bromeliales | Ananas comosus | Pineapple | 43 | Ana c 1 | Profilin | 15 kDa | 8 out of 19 sera (42%) from pineapple-sensitive patients showed IgE binding to recombinant Ana c 1 on immunoblot. IgE binding to pineapple extract (1 patient tested) was strongly inhibited by pineapple profilin (about 80%). | 12065910 | 1 | 2003-06-19 12:00:00 | 2019-07-03 18:06:35 | |
| Plantae Liliopsida (monocots) | Bromeliales | Ananas comosus | Pineapple | 44 | Ana c 2 | Bromelain | 22.8 kDa | 627040, 498487, 3233722 | 1 | 2006-11-03 12:00:00 | 2019-07-03 18:20:06 | ||
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 48 | Ani s 1 | unknown function, similar to Kunitz serine protease inhibitors | 24 kDa | Of 20 parasite-positive sera, 85% had specific IgE to purified Ani s 1 in immunoblotting studies. 45% of the sera had specific IgG4. - Of 49 Anisakis simplex-sensitive patients, 68% showed IgE binding to Ani s 1 on immunoblot: | 10887322 | 1 | 2003-05-13 12:00:00 | 2019-07-03 18:39:58 | |
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 49 | Ani s 2 | Paramyosin | 97 kDa | Of 26 A.simplex-sensitive patients, 23 (88%) showed IgE binding to purified Ani s 2 in ELISA, and 6 (23%) to rAni s 2. IgE binding to A. simplex was inhibited up to 11%, both by native and rAni s 2. | 11060483 | 1 | 2003-05-13 12:00:00 | 2019-07-03 18:40:14 | |
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 50 | Ani s 3 | Tropomyosin | 41 kDa | None of the 10 A.simplex-sensitive patients showed IgE binding to native or rAni s 3. Cross-reactivity with tropomyosins from other invertebrates is responsible for high titers of specific IgE in asymptomatic subjects | 11003461 | 1 | 2003-05-13 12:00:00 | 2019-07-03 18:40:25 | |
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 51 | Ani s 4 | Cysteine protease inhibitor | 9 kDa | 27% of sensitized subjects reacted to Ani s 4 | 15895253 | 1 | 2006-02-25 12:00:00 | 2019-07-03 18:41:51 | |
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 52 | Ani s 5 | SXP/RAL-2 family protein | 15 kDa | 7 of 28 sera were positive in direct ELISA using the recombinant protein | 1 | 2007-06-05 12:00:00 | 2019-07-03 18:42:26 | ||
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 53 | Ani s 6 | Serine protease inhibitor | 5 of 28 sera were positive in direct ELISA using the recombinant protein | 17180690 | 1 | 2007-06-05 12:00:00 | 2019-07-03 18:48:50 | ||
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 54 | Ani s 7 | 139 kDa | 1 | 2007-02-19 12:00:00 | 2019-07-03 18:50:06 | ||||
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 55 | Ani s 8 | SXP/RAL-2 family protein | 15 kDa | Of 28 A. simplex allergic patients (history of allergic reactions to fish, positive CAP-RAST to A. simplex, negative CAP-RAST to fish), 7 had IgE to purified Ani s 8 as show by ELISA. | 17689675 | 1 | 2007-10-30 12:00:00 | 2019-07-03 18:50:33 | |
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 56 | Ani s 9 | SXP/RAL-2 family protein | 14 kDa | 1 | 2007-10-30 12:00:00 | 2019-07-03 18:50:53 | |||
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 667 | Ani s 10 | Protein with unknown function | 21 kDa | 30 of 77 Anisakis allergic individuals had IgE that bound to the recombinant Ani s 10 in non-reducing immunoblots. | 21310242 | 1 | 2010-01-27 12:00:00 | 2019-07-03 19:17:54 | |
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 706 | Ani s 11 | Protein with unknown function | 27 kDa | 1 | 2011-01-12 12:00:00 | 2019-07-03 19:13:08 | |||
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 707 | Ani s 12 | Protein with unknown function | 31 kDa | 1 | 2011-01-12 12:00:00 | 2019-07-03 18:55:41 | |||
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 797 | Ani s 13 | Hemoglobin | 37 kDa | Twenty eight of 44 case-history positive subjects diagnosed with Gastro-allergic Anisakiasis or Anisakis sensitization associated chronic urticaria, had demonstrable IgE binding to the protein by hemoglobin-specific capture ELISA. | 25683373 | 1 | 2015-03-29 12:00:00 | 2019-07-03 18:54:30 | |
| Animalia Nematoda | Ascaridida | Anisakis simplex | Herring worm | 824 | Ani s 14 | 3rd stage larval protein unknown function | 24 kDa as deduced, 27 kDa on gel with His-tag | 14 out of 26 patients reactive to proteins of Anisakis, not to fish, were tested positive on ELISA using purified recombinant allergen expressed in E. coli. | 26537648 | 1 | 2016-02-21 12:00:00 | 2019-07-03 18:53:24 | |
| Animalia Arthropoda | Diptera | Anopheles dirus B (A. cracens) | Malaria mosquito SE Asia | 940 | Ano d 2 | Salivary odorant binding protein D7 | 15 kDa | 9 of 15 subjects with immediate or delayed skin reactions to mosquito bites were donors for serum IgE binding in immunoblots. One non-allergic subject was also tested. | 4 | 2018-10-09 23:53:18 | 2022-09-19 15:42:32 | ||
| Plantae Liliopsida (monocots) | Poales | Anthoxanthum odoratum | Sweet vernal grass | 57 | Ant o 1 | Beta-expansin | 25-35 kDa | IgE binding to 25-35 kD protein in immunoblot. Purified major allergen not found. Presence in extract determined by group 1 specific antiserum and by IgE binding/inhibition experiments | 9500760 | 2 | 2003-02-06 12:00:00 | 2020-05-14 16:35:24 | |
| Animalia Arthropoda | Hymenoptera | Apis cerana | Asiatic honey bee | 58 | Api c 1 | Phospholipase A2 | 16 kDa | no information found | 4 | 2003-05-22 12:00:00 | 2019-07-08 23:25:08 | ||
| Animalia Arthropoda | Hymenoptera | Apis dorsata | Giant honeybee | 59 | Api d 1 | Phospholipase A2 | 16 kDa | no information found | 4 | 2003-05-22 12:00:00 | 2019-07-08 23:26:48 | ||
| Animalia Arthropoda | Hymenoptera | Apis mellifera | Honey bee | 65 | Api m 1 | Phospholipase A2 | 16 kDa | 9 of 13 bee-allergic patients tested showed upregulation of the activation marker CD203c on basophils in response to Api m 1. - IgE binding to purified honey bee phospholipase in RAST (9 patients tested): medline 89277565 | 12403934 | 4 | 2003-05-22 12:00:00 | 2019-07-09 08:27:03 | |
| Animalia Arthropoda | Hymenoptera | Apis mellifera | Honey bee | 67 | Api m 2 | Hyaluronidase | 44 kDa | All 13 patients with bee allergy tested showed increased expression of the activation marker CD203c after stimulation of the basophils with purified Api m 2. - IgE binding to honeybee hyaluronidase in RAST (9 patients tested): medline 89277565 | 12403934 | 4 | 2003-05-22 12:00:00 | 2019-07-09 08:53:27 | |
| Animalia Arthropoda | Hymenoptera | Apis mellifera | Honey bee | 68 | Api m 3 | Acid phosphatase | 43 kDa | In immunoassays, recombinant Api m 3 is specifically recognized by IgE antibodies of pooled serum in Western blots and by 37% of the individual sera of honeybee venom-sensitized patients in ELISA analysis. | 16630944 | 4 | 2003-06-12 12:00:00 | 2019-07-09 08:28:14 | |
| Animalia Arthropoda | Hymenoptera | Apis mellifera | Honey bee | 69 | Api m 4 | Melittin | 3 kDa | Api m 3 | Elevated serum IgE antibodies to melittin were found in 7 of 24 honeybee venom-sensitive persons and in 5 of 20 nonsensitive beekeepers, measured by RAST. - None of the 13 bee-allergic patients tested showed upregulation of the activation marker CD203c on basophils in response to Api m 4: medline 2291906. | 850023 | 4 | 2003-05-27 12:00:00 | 2019-07-09 08:28:44 |
| Animalia Arthropoda | Hymenoptera | Apis mellifera | Honey bee | 70 | Api m 5 | Dipeptidylpeptidase IV | 100 kDa | Allergen C | IgE from 56% of the sera of 35 bee venom allergic individuals reacted with rApi m 5.0101 in ELISA. | 4 | 2008-07-11 12:00:00 | 2019-07-09 08:29:19 | |
| Animalia Arthropoda | Hymenoptera | Apis mellifera | Honey bee | 71 | Api m 6 | 8 kDa | Of 43 sera from Apis mellifera-allergic patients, 18 (42%) showed IgE binding to Api m 6 on immunoblot of bee venom extract. Purified Api m 6 was also recognized on immunoblot. | 11344362 | 4 | 2003-06-12 12:00:00 | 2019-07-09 08:29:46 | ||
| Animalia Arthropoda | Hymenoptera | Apis mellifera | Honey bee | 72 | Api m 7 | CUB serine protease | 39 kDa | IgE binding was detectable to the 39-kd band in immunoblot studies in 80% of the sera studied. Sera were collected from patients allergic to European Polistes from Italy and Spain. | 15480337 | 4 | 2003-05-27 12:00:00 | 2019-07-11 00:17:26 | |
| Animalia Arthropoda | Hymenoptera | Apis mellifera | Honey bee | 73 | Api m 8 | Carboxylesterase | 70 kDa | 46% of the sera from 28 bee venom allergic individuals had IgE that reacted with rApi m 8.0101 in ELISA. | 4 | 2008-07-11 12:00:00 | 2019-07-09 08:30:32 | ||
| Animalia Arthropoda | Hymenoptera | Apis mellifera | Honey bee | 74 | Api m 9 | Serine carboxypeptidase | 60 kDa | 4 | 2009-05-26 12:00:00 | 2019-07-09 08:31:05 | |||
| Animalia Arthropoda | Hymenoptera | Apis mellifera | Honey bee | 66 | Api m 10 | Icarapin variant 2, carbohydrate-rich protein | 50-55 kDa | 4 | 2009-12-07 12:00:00 | 2019-07-09 08:31:40 | |||
| Animalia Arthropoda | Hymenoptera | Apis mellifera | Honey bee | 731 | Api m 11 | Major royal jelly protein | 50 kDa (deglycosylated form) | See isoallergens | 22909169,19287364,21389615,35234637 | 4 | 2011-07-20 12:00:00 | 2024-07-18 13:30:10 | |
| Animalia Arthropoda | Hymenoptera | Apis mellifera | Honey bee | 735 | Api m 12 | Vitellogenin | 200 kDa | Of 45 bee venom-allergic patients (history + sIgE or SPT) 20 (44%) showed specific IgE reactivity in an ELISA with recombinant Api m 12.0101 produced in M9 insect cells. | 23626765 | 4 | 2012-02-27 12:00:00 | 2024-04-08 17:13:58 | |
| Plantae Eudikotyledons | Apiales | Apium graveolens | Celery | 60 | Api g 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 16 kDa | All 10 celery-allergic patients tested showed serum IgE binding to natural Api g 1 in celery extract, and to purified rApi g 1 on immunoblot - All 10 celery-allergic patients tested showed serum IgE binding to natural Api g 1 and recombinant Api g 1.0101 on immunoblot. In general, rApi g 1.0101 exhibited a stronger IgE-binding capacity as compared to rApi g 1.0201. | 7588792 | 1 | 2003-06-17 12:00:00 | 2020-05-13 18:20:13 | |
| Plantae Eudikotyledons | Apiales | Apium graveolens | Celery | 61 | Api g 2 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | IgE testing showed a sensitization prevalence of 25.6% to Api g 2 among 786 tested Mediterranean subjects. 10/32 patients suffering from LTP-related allergy reported symptoms upon consumption of celery stalks which mainly presented as OAS. | 21897872 | 1 | 2009-08-21 12:00:00 | 2025-04-10 18:27:18 | |
| Plantae Eudikotyledons | Apiales | Apium graveolens | Celery | 62 | Api g 3 | Chlorophyll a-b binding protein, chloroplast | 28 kDa | 1 | 2003-06-17 12:00:00 | 2019-07-09 00:08:16 | |||
| Plantae Eudikotyledons | Apiales | Apium graveolens | Celery | 63 | Api g 4 | Profilin | 14 kDa | Of 13 celery-allergic patients tested, 3 (23%) showed serum IgE binding to recombinant Api g 4 on immunoblot. rApi g 4 induced histamine release (max 70%) from basophils in 1 patient tested. | 10848918 | 1 | 2003-06-17 12:00:00 | 2019-07-09 00:19:35 | |
| Plantae Eudikotyledons | Apiales | Apium graveolens | Celery | 64 | Api g 5 | FAD-containing oxidase | 58 kDa | All 5 celery-(and birch pollen)allergic patients tested showed serum IgE binding to Api g 5 (identified by N-terminal sequencing) on immunoblot of celery extract. | 10718855 | 1 | 2003-06-17 12:00:00 | 2019-07-09 00:20:05 | |
| Plantae Eudikotyledons | Apiales | Apium graveolens | Celery | 725 | Api g 6 | Non-specific lipid transfer protein type 2 (nsLTP2) | 7 kDa | Thirty-eight percent of A. graveolens allergic patients demonstrated IgE reactivity to natural Api g 6 purified from celery tuber. No correlation in IgE binding and limited cross-reactivity was observed with Api g 2 and Art v 3, nsLTP1 from celery stalks and mugwort pollen. | 23913675 | 1 | 2013-12-19 12:00:00 | 2025-04-10 18:29:35 | |
| Plantae Eudikotyledons | Apiales | Apium graveolens | Celery | 1062 | Api g 7 | Defensin like protein 1 | 12 kDa | 41 of 79 subjects who were positive in double blind placebo controlled food challenge were positive by IgE binding in ImmunoCAP. 12 negative controls. | 34908171 | 1 | 2021-05-31 17:06:44 | 2024-09-18 18:29:03 | |
| Animalia Arthropoda | Hymenoptera | Apoica pallens | Central American paper wasp | 1160 | Apo p 1 | Phospholipase A1 | 33 kDa | All twenty patients included in the study had clinical manifestations of anaphylaxis (grade III or IV) to wasp or hornet stings. In addition, the patients had positive SPT to wasp venom and sIgE to common wasp venom (ImmunoCAP i3) and/or paper wasp venom (ImmunoCAP i4). All 20 sera had IgE to Apoica pallans venom extract and to nApo p 1 determined by ELISA. | 39844010 | 4 | 2024-11-12 12:06:14 | 2025-02-04 15:00:17 | |
| Animalia Arthropoda | Hymenoptera | Apoica pallens | Central American paper wasp | 1161 | Apo p 5 | Antigen 5 | 23 kDa | All twenty patients included in the study had clinical manifestations of anaphylaxis (grade III or IV) to wasp or hornet stings. In addition, the patients had positive SPT to wasp venom and sIgE to common wasp venom (ImmunoCAP i3) and/or paper wasp venom (ImmunoCAP i4). All 20 sera had IgE to Apoica pallans venom extract and to nApo p 5 determined by ELISA. | 39844010 | 4 | 2024-11-12 12:15:02 | 2025-02-04 15:00:42 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 75 | Ara h 1 | Vicillin, 7S globulin seed storage protein (contains an N-terminal alpha-hairpinin) | 64 kDa | Of 18 peanut-allergic patients, 16 showed IgE binding to purified Ara h 1 on immunoblot. There were varying intensities of IgE binding of the patient sera. IgE binding to rAra h 1 was also demonstrated. - Of 40 peanut-allergic patients tested, 25 (63%) showed IgE binding to rAra h 1 on immunoblot: medline 99406463. | 7560062 | 1 | 2003-06-24 12:00:00 | 2025-08-26 12:29:51 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 78 | Ara h 2 | Conglutin (2S albumin) | 17 kDa | Of 40 peanut-allergic patients tested, 34 (85%) showed IgE binding to rAra h 2 on immunoblot. - In ELISA of partially purified Ara h 2, all 6 peanut-allergic patients tested had IgE Ab against Ara h 2: medline 93094482. - IgE binding epitopes: medline 22092281 and medline 97330026 | 10474031, 918645, 12759484 | 1 | 2003-10-27 12:00:00 | 2020-05-14 17:05:37 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 79 | Ara h 3 | Cupin (Legumin-type, 11S globulin, Glycinin) | 60 kDa, 37 kDa (fragment) | Ara h 4 (now isoallergen Ara h 3.02) | Of 18 peanut-allergic patients tested, 8 (44%) showed IgE binding to recombinant Ara h 3 on immunoblot. An immunodominant epitope on Ara h 3 was characterized. | 10021462 | 1 | 2003-06-24 12:00:00 | 2025-08-25 16:24:18 |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 80 | Ara h 4 | renamed to Ara h 3.02, number not available for future submissions | 10474031 | 1 | 2003-06-24 12:00:00 | 2012-05-04 14:21:14 | |||
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 81 | Ara h 5 | Profilin | 15 kDa | Of 40 peanut-allergic patients tested, 5 (13%) showed IgE binding to rAra h 5 on immunoblot | 10474031 | 1 | 2003-06-24 12:00:00 | 2019-07-10 07:50:55 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 82 | Ara h 6 | Conglutin (2S albumin) | 15 kDa | Of 40 peanut-allergic patients tested, 15 (38%) showed IgE binding to rAra h 6 on immunoblot. | 10474031 | 1 | 2003-06-24 12:00:00 | 2019-07-10 07:51:04 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 83 | Ara h 7 | Conglutin (2S albumin) | 15 kDa | Of 40 peanut-allergic patients tested, 17 (43%) showed IgE binding to rAra h 7 on immunoblot. | 10474031; 20443639 | 1 | 2003-06-24 12:00:00 | 2019-07-10 07:51:24 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 84 | Ara h 8 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 17 kDa | CAP-FEIA detected recombinant (r) Ara h 8-specific IgE in 85%. IgE binding to Ara h 8 was inhibited by Bet v 1 in peanut extract immunoblotting and in RAST inhibition. In EAST inhibition recombinant rAra h 8 inhibited IgE binding to peanut in 4 of 7 tested patient sera. | 15577846 | 1 | 2004-04-25 12:00:00 | 2019-07-10 07:51:55 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 85 | Ara h 9 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9.8 kDa | Nineteen (45.2%) sera of subjects with peanut allergy (n=42) had IgE antibodies to natural Ara h 9 by immunoblotting. | 19665774 | 1 | 2007-10-30 12:00:00 | 2025-04-10 18:27:36 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 76 | Ara h 10 | oleosin | 16 kDa | Blot/CAP with a purified natural oleosin fraction obtained from oilbodies from peanut. 7 patients with peanut ingestion related symptoms recognized the 16 kDa band. | 25860789 28342912 | 1 | 2008-07-11 12:00:00 | 2020-05-14 17:09:56 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 77 | Ara h 11 | oleosin | 14 kDa | Blot/CAP with a purified natural oleosin fraction obtained from oilbodies from peanut. 7 patients with peanut ingestion related symptoms recognized the 14 kDa band. | 25860789 28342912 | 1 | 2008-07-11 12:00:00 | 2020-05-14 17:11:20 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 753 | Ara h 12 | Defensin | 8 kDa (reducing), 12 kDa (non-reducing), 5.184 kDa (mass) | Four peanut allergic subjects with clear clinical histories and high IgE by ImmunoCAP to peanut had demonstrable IgE binding to non-reduced defensins. BAT was positive for a few subjects to a mixture of Ara h 12 and Ara h 13. | 26037551 | 1 | 2012-08-27 12:00:00 | 2024-06-28 18:28:31 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 754 | Ara h 13 | Defensin | 8 kDa (reducing), 11 kDa (non-reducing), 5.472 kDa (mass) | Five peanut allergic subjects with high peanut extract ImmunoCAP showed IgE binding to Ara h 13 in non-reducing immunoblot. Also at least two subjects had positive BAT to a mixture of Ara h 12 and Ara h 13. | 26037551 | 1 | 2013-08-27 12:00:00 | 2024-06-28 18:31:10 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 827 | Ara h 14 | Oleosin | 17.5 kDa | 15 of 33 subjects with peanut allergy had demonstrable IgE binding to this protein (based on communication with submission) | 25860789 28342912 | 1 | 2015-05-09 12:00:00 | 2024-09-13 16:03:21 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 828 | Ara h 15 | Oleosin 3 | 17 kDa | 15 of 33 subjects with peanut allergy had demonstrable IgE binding to this protein (based on communication with submission) | 25860789 28342912 | 1 | 2015-05-02 12:00:00 | 2025-08-25 17:02:40 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 830 | Ara h 16 | Non-specific lipid transfer protein type 2 (nsLTP2) | 8.5 kDa by SDS PAGE reducing | IgE binding to the native protein by RAST, with 4 positive out of 25 clinically proven peanut allergic subjects | 1 | 2015-05-22 12:00:00 | 2025-04-10 17:47:24 | ||
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 831 | Ara h 17 | Non-specific lipid transfer protein type 1 (nsLTP1) | 11 kDa by SDS-PAGE reducing | 4 of 25 clinically defined, peanut allergic subjects had IgE binding by RAST, and one peach LTP-positive, peach allergic subject was positive by RAST. | 1 | 2015-05-22 12:00:00 | 2025-04-10 17:48:34 | ||
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 1039 | Ara h 18 | Cyclophilin, peptidyl-prolyl cis-trans isomerase | 21 kDa | IgE to rAra h 18 was present in sera from 13 of 15 peanut sensitized subjects testing negative for IgE to Ara h 1, 2, 3, 6, 8, 9, profilin and CCD, at levels comparable or greater than to whole peanut extract. | 33497485 | 1 | 2020-11-13 19:58:04 | 2024-05-23 13:12:03 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 1181 | Ara h 19 | Annexin Gh1 | 39 kDa | Sera from 52 peanut-allergic patients were tested (positive open oral food challenge with peanut butter + positive peanut ImmunoCAP). Sera from 12 non-allergic donors served as negative controls. In an IgE-ELISA, 24 peanut-allergic patients' sera (46%) had IgE to rAra h 19.0101 produced in E. coli. | 41367265 | 1 | 2025-10-02 18:11:53 | 2025-12-12 12:17:36 | |
| Plantae Eudikotyledons | Fabales | Arachis hypogaea | Peanut, groundnut | 1182 | Ara h 20 | Seed biotinylated protein SBP65 | 57 kDa | Sera from 52 peanut-allergic patients were tested (positive open oral food challenge with peanut butter + positive peanut ImmunoCAP). Sera from 12 non-allergic donors served as negative controls. In an IgE-ELISA, 5 peanut-allergic patients' sera (10%) had IgE to rAra h 20.0101 produced in E. coli. | 41367265 | 1 | 2025-10-02 18:26:19 | 2025-12-12 12:19:39 | |
| Animalia Arthropoda | Decapoda | Archaeopotamobius sibiriensis | Crayfish | 86 | Arc s 8 | Triosephosphate isomerase | ~28 kDa | 11/25 (44%) shrimp allergic patients had IgE that reacted with Arc s 8 in IgE immunoblotting experiments. | 1 | 2009-01-23 12:00:00 | 2019-07-10 07:53:10 | ||
| Animalia Arthropoda | Ixodida | Argas reflexus | Pigeon tick | 87 | Arg r 1 | 17 kDa | 15753913 | 4 | 2004-10-27 12:00:00 | 2020-04-05 00:04:11 | |||
| Animalia Arthropoda | Anostraca | Artemia franciscana | Brine shrimp | 88 | Art fr 5 | Myosin, light chain 1 | ~17.5 kDa | 11/25 (44%) of shrimp allergic patients had IgE that reacted with Art fr 5 in IgE immunoblotting experiments. | 1 | 2009-01-23 12:00:00 | 2019-07-11 08:43:56 | ||
| Plantae Eudikotyledons | Asterales | Artemisia absinthium | Absinthe wormwood | 962 | Art ab 1 | Defensin-like protein with polyproline rich domain, Art v 1-like | 24 to 26 kDa | 11 subjects with summer rhinitis or conjunctivitis had positive IgE binding to natural Art ab 1 by western blot, ELISA and RAST. Subjects were SPT + to extracts of all Art v 1 samples tested in this study. Four of four had basophil activation by purified protein. Unpublished so far. | 2 | 2019-06-07 20:50:40 | 2025-08-25 17:03:56 | ||
| Plantae Eudikotyledons | Asterales | Artemisia annua | Sweet Wormwood | 963 | Art an 1 | Defensin-like protein with polyproline-rich domain, Art v 1-like | 24 to 26 kDa | Sera from 11 subjects with late summer conjunctivitis and rhinitis and SPT+ to extract of mugwort tested + in western blots, ELISA and RAST to purified natural protein. Four of four were positive by basophil activation. Protein has O-linked glycans. | 31434264, 33292509 | 2 | 2019-06-07 21:19:47 | 2025-08-25 17:04:24 | |
| Plantae Eudikotyledons | Asterales | Artemisia annua | Sweet Wormwood | 1027 | Art an 2 | Pathogenesis related protein PR-1 | 18 kDa | 24 of 29 pollen allergic subjects in China were positive in IgE binding to natural protein by ImmunoCAP | 2 | 2020-10-10 19:31:01 | 2025-08-28 12:01:55 | ||
| Plantae Eudikotyledons | Asterales | Artemisia annua | Sweet Wormwood | 1032 | Art an 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | 14 of 28 pollen allergic subjects in China had IgE binding to recombinant protein by ImmunoCAP | 2 | 2020-10-10 20:03:03 | 2025-04-10 17:55:33 | ||
| Plantae Eudikotyledons | Asterales | Artemisia annua | Sweet Wormwood | 1091 | Art an 4 | Profilin | 14 kDa | 25 people with airway allergy were positive by IgE ELISA to this recombinant protein which is 100% identical to Art v 4. rArt an 4 was cross-reactive with rMan i 4 from mango. | 36724175 | 2 | 2022-02-24 00:13:28 | 2026-05-28 14:14:26 | |
| Plantae Eudikotyledons | Asterales | Artemisia annua | Sweet Wormwood | 898 | Art an 7 | Putative Galactose Oxidase | 62 kDa | Case history of weed pollen inhalation allergy, in vitro IgE to mugwort extract, to natural purified protein (15 Chinese subjects by reducing immunoblot) and 125 of 130 Chinese subjects by ImmunoCAP, 15 of 15 by IgE reducing immunoblot, but fewer with recombinant protein as seen in draft manuscript. With only one clearly positive in ImmunoCAP with recombinant protein. Dutch pollen allergic subjects, 19 of 20 were positive by natural purified protein ImmunoCAP, but only 10 to recombinant protein, and those values were only modest (>0.35 kUA to 1.8 kUA). Four of 8 Chinese subjects were positive to natural pure protein by SPT. There is some possible involvement of carbohydrate (CCD+ and also possibly to arabinofuranosides based on paper by Xie Ning and CM Taylor, 2014). | 29220102 | 2 | 2017-04-05 14:02:30 | 2019-07-10 07:57:37 | |
| Plantae Eudikotyledons | Asterales | Artemisia annua | Sweet Wormwood | 1120 | Art an 14 | Fructose bisphosphate aldolase | 38 kDa | Sera from 20 pollen-allergic patients (allergic rhinitis and/or asthma) sensitized to Artemisia pollen (ImmunoCAP class >= 3 with A. vulgaris ImmunoCAP) were tested. Of those, 9 (45%) had IgE to recombinant Art an 14.0101, produced in E. coli. In a BAT assay with 3 Art an 14-sensitized patients, 2 of 3 reacted with rArt an 14.0101. In an IgE ELISA with a pool of Art an 14-sensitized sera, a high extent of IgE cross-reactivity with Art si 14 was shown. | 38375932 | 2 | 2022-10-17 17:20:57 | 2024-09-18 18:09:59 | |
| Plantae Eudikotyledons | Asterales | Artemisia argyi | Silvery wormwood | 1022 | Art ar 1 | Defensin-like protein with polyproline-rich domain, Art v 1-like | 28 kDa | 14 of 18 pollen positive subjects in China were positive by IgE binding to natural and recombinant protein by ELISA and ImmunoCAP | 2 | 2020-10-10 18:05:15 | 2025-08-25 17:04:51 | ||
| Plantae Eudikotyledons | Asterales | Artemisia argyi | Silvery wormwood | 907 | Art ar 2 | Pathogenesis-related protein PR-1 | 18 kDa | 48% of 240 Artemisia pollen allergic subjects had IgE binding using ImmunoCAP to natural Art ar 2. | 30155917 | 2 | 2017-11-24 02:06:03 | 2025-08-28 12:02:32 | |
| Plantae Eudikotyledons | Asterales | Artemisia argyi | Silvery wormwood | 1033 | Art ar 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | 15 of 26 serum donors in China with pollen allergy had positive IgE binding to natural protein by ImmunoCAP | 2 | 2020-10-10 20:36:18 | 2025-04-10 17:58:31 | ||
| Plantae Eudikotyledons | Asterales | Artemisia californica | California sagebrush | 976 | Art c 1 | Defensin-like protein with polyproline-rich domain, Art v 1-like | 24 to 26 kDa | pollen airway allergy, 11 of 11 subjects allergic to Art v 1 had IgE binding to natural Art c 1 while no IgE binding was seen for 2 controls. Four of 4 were positive by Basophil Activation to Art c 1. | 2 | 2019-08-13 18:21:24 | 2025-08-25 17:05:24 | ||
| Plantae Eudikotyledons | Asterales | Artemisia capillaris | Capillary wormwood | 1023 | Art ca 1 | Defensin-like protein with polyproline-rich domain, Art v 1-like | 28 kDa | 17 of 25 Subjects in China, with pollen allergy had IgE binding to Natural protein by ImmunoCAP | 2 | 2020-10-10 18:43:48 | 2025-08-25 17:05:45 | ||
| Plantae Eudikotyledons | Asterales | Artemisia capillaris | Capillary wormwood | 1028 | Art ca 2 | Pathogenesis-related protein PR-1 | 18 kDa | 9 of 21 pollen allergic subjects in China were positive by IgE binding to natural protein by ImmunoCAP | 2 | 2020-10-10 19:37:54 | 2025-08-28 12:03:12 | ||
| Plantae Eudikotyledons | Asterales | Artemisia capillaris | Capillary wormwood | 1034 | Art ca 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | 14 of 28 Chinese pollen allergic subjects had IgE binding to recombinant protein by ImmunoCAP | 2 | 2020-10-10 20:47:10 | 2025-04-10 17:59:46 | ||
| Plantae Eudikotyledons | Asterales | Artemisia desertorum | Desert wormwood | 1168 | Art d 1 | Defensin-like protein with C-terminal hydroxyproline-rich domain | 25-30 kDa | Sera from 95 patients from Northern China allergic to Artemisia pollen (symptoms + SPT to A. desertorum and/or ImmunoCAP to A. vulgaris) were tested by ImmunoCAP. In an initial experiment, eight of 10 tested sera (80%) had IgE to nArt d 1, rArt d 1.0101 and rArt d 1.0102 with similar IgE binding capacities of both allergen variants. All 95 sera were tested with rArt v 1.0101 with positive IgE measured in 80 sera (84%). | 41668300 | 2 | 2025-09-03 14:27:30 | 2026-02-11 13:23:56 | |
| Plantae Eudikotyledons | Asterales | Artemisia desertorum | Desert wormwood | 1169 | Art d 2 | Pathogenesis-related protein PR-1 | 17 kDa | Sera from 95 patients from Northern China allergic to Artemisia pollen (symptoms + SPT to A. desertorum and/or ImmunoCAP to A. vulgaris) were tested by ImmunoCAP. Of those, 67 sera (71%) had IgE to nArt d 2. | 41668300 | 2 | 2025-09-03 16:29:18 | 2026-02-11 13:26:03 | |
| Plantae Eudikotyledons | Asterales | Artemisia desertorum | Desert wormwood | 1170 | Art d 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | Sera from 95 patients from Northern China allergic to Artemisia pollen (symptoms + SPT to A. desertorum and/or ImmunoCAP to A. vulgaris) were tested by ImmunoCAP. Of those, 88 sera (93%) had IgE to nArt d 3. | 41668300 | 2 | 2025-09-03 16:42:05 | 2026-02-11 13:55:49 | |
| Plantae Eudikotyledons | Asterales | Artemisia desertorum | Desert wormwood | 1171 | Art d 4 | Profilin | 14 kDa | Sera from 95 patients from Northern China allergic to Artemisia pollen (symptoms + SPT to A. desertorum and/or ImmunoCAP to A. vulgaris) were tested by ImmunoCAP. Of those, 43 sera (45%) had IgE to rArt d 4.0101. | 41668300 | 2 | 2025-09-03 17:10:22 | 2026-02-11 14:01:10 | |
| Plantae Eudikotyledons | Asterales | Artemisia desertorum | Desert wormwood | 1172 | Art d 5 | Polcalcin | 9 kDa | Sera from 95 patients from Northern China allergic to Artemisia pollen (symptoms + SPT to A. desertorum and/or ImmunoCAP to A. vulgaris) were tested by ImmunoCAP. Of those, 24 sera (25%) had IgE to rArt d 5.0101. | 41668300 | 2 | 2025-09-03 17:33:20 | 2026-02-11 14:01:44 | |
| Plantae Eudikotyledons | Asterales | Artemisia desertorum | Desert wormwood | 1173 | Art d 6 | Pectate lyase | 45 kDa | Sera from 95 patients from Northern China allergic to Artemisia pollen (symptoms + SPT to A. desertorum and/or ImmunoCAP to A. vulgaris) were tested by ImmunoCAP. Of those, 12 sera (13%) had IgE to rArt d 6.0101. | 41668300 | 2 | 2025-09-03 17:40:38 | 2026-02-11 14:02:20 | |
| Plantae Eudikotyledons | Asterales | Artemisia desertorum | Desert wormwood | 1174 | Art d 7 | Galactose oxidase | 65 kDa | Sera from 95 patients from Northern China allergic to Artemisia pollen (symptoms + SPT to A. desertorum and/or ImmunoCAP to A. vulgaris) were tested by ImmunoCAP. Of those, 84 sera (88%) had IgE to nArt d 7. | 41668300 | 2 | 2025-09-03 18:00:41 | 2026-02-11 14:02:53 | |
| Plantae Eudikotyledons | Asterales | Artemisia desertorum | Desert wormwood | 1175 | Art d 8 | Superoxide dismutase | 15 kDa | Sera from 95 patients from Northern China allergic to Artemisia pollen (symptoms + SPT to A. desertorum and/or ImmunoCAP to A. vulgaris) were tested by ImmunoCAP. Of those, 12 sera (13%) had IgE to rArt d 8.0101. | 41668300 | 2 | 2025-09-03 18:37:37 | 2026-02-11 14:03:29 | |
| Plantae Eudikotyledons | Asterales | Artemisia desertorum | Desert wormwood | 1176 | Art d 9 | Cyclophilin, peptidyl-prolyl cis-trans isomerase | 18 kDa | Sera from 95 patients from Northern China allergic to Artemisia pollen (symptoms + SPT to A. desertorum and/or ImmunoCAP to A. vulgaris) were tested by ImmunoCAP. Of those, 56 sera (59%) had IgE to rArt d 9.0101. | 41668300 | 2 | 2025-09-03 18:42:06 | 2026-02-11 14:05:20 | |
| Plantae Eudikotyledons | Asterales | Artemisia desertorum | Desert wormwood | 1177 | Art d 12 | Enolase | 48 kDa | Sera from 95 patients from Northern China allergic to Artemisia pollen (symptoms + SPT to A. desertorum and/or ImmunoCAP to A. vulgaris) were tested by ImmunoCAP. Of those, 57 sera (60%) had IgE to rArt d 12.0101. | 41668300 | 2 | 2025-09-03 18:45:50 | 2026-02-11 14:04:01 | |
| Plantae Eudikotyledons | Asterales | Artemisia desertorum | Desert wormwood | 1178 | Art d 14 | Fructose bisphosphate aldolase | 40 kDa | Sera from 95 patients from Northern China allergic to Artemisia pollen (symptoms + SPT to A. desertorum and/or ImmunoCAP to A. vulgaris) were tested by ImmunoCAP. Of those, 24 sera (25%) had IgE to rArt d 14.0101. | 41668300 | 2 | 2025-09-03 18:50:34 | 2026-02-11 14:07:54 | |
| Plantae Eudikotyledons | Asterales | Artemisia frigida | Prairie sagebrush | 964 | Art f 1 | Defensin-like protein with polyproline rich domain, Art v 1-like | 24 to 26 kDa | Sera from 11 subjects with late summer conjunctivitis or rhinitis tested positive by western blot and ELISA to purified natural protein. Subjects were positive by SPT+ to extract of mugwort. Four of four were positive in basophil activation. Not published yet. | 2 | 2019-06-07 21:51:46 | 2025-08-25 17:03:25 | ||
| Plantae Eudikotyledons | Asterales | Artemisia gmelinii | Russian wormwood | 1024 | Art gm 1 | Defensin-like protein with polyproline-rich domain, Art v 1-like | 28 kDa | 13 of 20 pollen allergic subjects in China were positive in IgE binding to natural protein by ELISA | 2 | 2020-10-10 18:56:04 | 2025-08-25 17:06:17 | ||
| Plantae Eudikotyledons | Asterales | Artemisia gmelinii | Russian wormwood | 1029 | Art gm 2 | Pathogenesis-related protein PR-1 | 18 kDa | 24 of 29 pollen allergic subjects in China were positive in IgE binding to natural protein by ImmunoCAP | 2 | 2020-10-10 19:45:18 | 2025-08-28 12:03:44 | ||
| Plantae Eudikotyledons | Asterales | Artemisia gmelinii | Russian wormwood | 1035 | Art gm 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | 15 of 26 Chinese pollen allergic subjects were positive in IgE binding to natural protein by ImmunoCAP | 2 | 2020-10-10 20:59:26 | 2025-04-10 18:00:20 | ||
| Plantae Eudikotyledons | Asterales | Artemisia lavandulifolia | Lavender-leaved mugwort | 1025 | Art la 1 | Defensin-like protein with polyproline-rich domain, Art v 1-like | 28 kDa | 13 of 20 pollen allergic subjects in China were positive in IgE binding to natural protein by ELISA | 2 | 2020-10-10 19:02:33 | 2025-08-25 17:06:32 | ||
| Plantae Eudikotyledons | Asterales | Artemisia lavandulifolia | Lavender-leaved mugwort | 1030 | Art la 2 | Pathogenesis-related protein PR-1 | 18 kDa | 8 of 21 subjects in China with pollen allergy had IgE binding to natural protein by ImmunoCAP | 2 | 2020-10-10 19:51:04 | 2025-08-28 12:04:19 | ||
| Plantae Eudikotyledons | Asterales | Artemisia lavandulifolia | Lavender-leaved mugwort | 1036 | Art la 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | 16 of 27 Chinese subject's IgE was positive in binding to natural protein by ImmunoCAP | 2 | 2020-10-10 21:10:14 | 2025-04-10 18:01:00 | ||
| Plantae Eudikotyledons | Asterales | Artemisia ludoviciana | Silver wormwood | 965 | Art l 1 | Defensin-like protein with polyproline rich domain, Art v 1-like | 24-26 kDa | Sera from 11 subjects with late summer rhinitis and conjunctivitis were tests after demonstrating positive SPT to Art v extract. All 11 were positive by western blot and by ELISA to purified protein and four of four were positive by basophil activation. unpublished now. | 2 | 2019-06-07 22:02:24 | 2025-08-25 17:07:00 | ||
| Plantae Eudikotyledons | Asterales | Artemisia ordosica | Ordos desert wormwood | 1193 | Art o 4 | Profilin | 14 kDa | Sera were collected from 107 patients during the Artemisia ordosica pollen season. Allergic patients were selected based on typical clinical symptoms of allergic rhinitis, a self-reported history of allergy to A. ordosica and sIgE to A. ordosica extract measured by ELISA. A control group of 50 healthy subjects without any symptoms of allergic rhinitis and no known allergy to A. ordosica pollen was included. IgE from 76 of 107 (71%) allergic patients' sera and 3 of 50 (6%) control sera bound to recombinant Art o 4.0101, expressed in E. coli. The recombinant allergen inhibited IgE binding to A. ordosica pollen extract by up to 45% using a pool of Art o 4-positive sera. | 2 | 2026-05-28 14:18:05 | 2026-05-28 14:18:05 | ||
| Plantae Eudikotyledons | Asterales | Artemisia ordosica | Ordos desert wormwood | 1195 | Art o 6 | Pectate lyase | 47 kDa | Sera were collected from 107 patients during the Artemisia ordosica pollen season. Allergic patients were selected based on typical clinical symptoms of allergic rhinitis, a self-reported history of allergy to A. ordosica and sIgE to A. ordosica extract measured by ELISA. A control group of 50 healthy subjects without any symptoms of allergic rhinitis and no known allergy to A. ordosica pollen was included. IgE from 87 of 107 (81%) allergic patients' sera and 1 of 50 (2%) control sera bound to recombinant Art o 6.0101, expressed in E. coli. The recombinant allergen inhibited IgE binding to A. ordosica pollen extract by up to 43% using a pool of Art o 6-positive sera. | 2 | 2026-05-28 15:36:21 | 2026-05-28 15:36:21 | ||
| Plantae Eudikotyledons | Asterales | Artemisia ordosica | Ordos desert wormwood | 1196 | Art o 11 | Papin-like cysteine protease | 37 kDa (proprotein with N-terminal propeptide) | See isoallergens | 2 | 2026-05-28 16:16:51 | 2026-05-28 16:36:01 | ||
| Plantae Eudikotyledons | Asterales | Artemisia ordosica | Ordos desert wormwood | 1197 | Art o 12 | Enolase (fragment) | 38 kDa | Sera were collected from 107 patients during the Artemisia ordosica pollen season. Allergic patients were selected based on typical clinical symptoms of allergic rhinitis, a self-reported history of allergy to A. ordosica and sIgE to A. ordosica extract measured by ELISA. A control group of 50 healthy subjects without any symptoms of allergic rhinitis and no known allergy to A. ordosica pollen was included. IgE from 32 of 107 (30%) allergic patients' sera and 1 of 50 (2%) control sera bound to recombinant Art o 12.0101, expressed in E. coli. The recombinant allergen inhibited IgE binding to A. ordosica pollen extract by up to 28% using a pool of Art o 12-positive sera. | 2 | 2026-05-28 16:58:13 | 2026-05-28 17:06:11 | ||
| Plantae Eudikotyledons | Asterales | Artemisia ordosica | Ordos desert wormwood | 1192 | Art o 19 | Thioredoxin | 13 kDa | Sera were collected from 107 patients during the Artemisia ordosica pollen season. Allergic patients were selected based on typical clinical symptoms of allergic rhinitis, a self-reported history of allergy to A. ordosica and sIgE to A. ordosica extract measured by ELISA. A control group of 50 healthy subjects without any symptoms of allergic rhinitis and no known allergy to A. ordosica pollen was included. IgE from 16 of 107 (15%) allergic patients' sera and 2 of 50 (4%) control sera bound to recombinant Art o 19.0101, expressed in E. coli. The recombinant allergen inhibited IgE binding to A. ordosica pollen extract by up to 24% using a pool of Art o 19-positive sera. | 2 | 2026-05-28 12:46:48 | 2026-05-28 12:46:48 | ||
| Plantae Eudikotyledons | Asterales | Artemisia ordosica | Ordos desert wormwood | 1194 | Art o 20 | Malate dehydrogenase (fragment) | 25 kDa | Sera were collected from 107 patients during the Artemisia ordosica pollen season. Allergic patients were selected based on typical clinical symptoms of allergic rhinitis, a self-reported history of allergy to A. ordosica and sIgE to A. ordosica extract measured by ELISA. A control group of 50 healthy subjects without any symptoms of allergic rhinitis and no known allergy to A. ordosica pollen was included. IgE from 24 of 107 (22%) allergic patients' sera and none of 50 control sera bound to recombinant Art o 20.0101, expressed in E. coli. The recombinant allergen inhibited IgE binding to A. ordosica pollen extract by up to 27% using a pool of Art o 20-positive sera. | 2 | 2026-05-28 14:55:32 | 2026-05-28 17:05:55 | ||
| Plantae Eudikotyledons | Asterales | Artemisia sieversiana | Sieversian wormwood | 1026 | Art si 1 | Defensin-like protein with polyproline-rich domain, Art v 1-like | 28 kDa | 14 of 18 pollen allergic subjects from China had positive IgE binding to recombinant protein by ELISA | 2 | 2020-10-10 19:19:52 | 2025-08-25 17:07:30 | ||
| Plantae Eudikotyledons | Asterales | Artemisia sieversiana | Sieversian wormwood | 1031 | Art si 2 | Pathogenesis-related protein PR-1 | 18 kDa | 14 of 20 pollen allergic subjects in China had Positive IgE binding to natural protein by ImmunoCAP | 2 | 2020-10-10 19:56:40 | 2025-08-28 12:05:01 | ||
| Plantae Eudikotyledons | Asterales | Artemisia sieversiana | Sieversian wormwood | 1037 | Art si 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | 14 of 20 Chinese pollen allergic subjects had positive IgE binding to natural protein by ImmunoCAP | 2 | 2020-10-10 21:26:08 | 2025-04-10 18:01:34 | ||
| Plantae Eudikotyledons | Asterales | Artemisia sieversiana | Sieversian wormwood | 1067 | Art si 5 | Polcalcin | 9 kDa | 130 people claiming pollen allergy to Sieversian wormwood with 4 of those positive in IgE binding by western blot and ELISA to recombinant protein | 36372651 | 2 | 2021-08-03 03:22:23 | 2024-09-18 18:39:13 | |
| Plantae Eudikotyledons | Asterales | Artemisia sieversiana | Sieversian wormwood | 1152 | Art si 6 | Pectate lyase | 39 kDa | Sera from 15 pollen-allergic patients with allergic rhinitis and/or asthma and a positive ImmunoCAP to mugwort pollen were tested. Of those, 6 (40%) had specific IgE to natural Art si 6 and recombinant Art si 6.0101 produced in E. coli as determined by ELISA. Five of 6 ELISA-positive sera bound to rArt si 6 in an immunoblot. In an inhibition ELISA, natural and recombinant Art si 6 inhibited IgE binding to Art si pollen extract by 76% and 47%, respectively. The recombinant allergen activated basophils sensitized with sera from three ELISA-positive patients in an indirect BAT. | 38897183 | 2 | 2024-06-26 17:11:15 | 2024-09-17 16:23:04 | |
| Plantae Eudikotyledons | Asterales | Artemisia sieversiana | Sieversian wormwood | 1069 | Art si 8 | Superoxide dismutase | 17 kDa | 90 Subjects claiming allergy to pollen of Sieversian wormwood were tested and 9 were positive to IgE binding to recombinant protein by ELISA and immunoblot | 2 | 2021-08-03 03:59:52 | 2022-04-29 15:56:38 | ||
| Plantae Eudikotyledons | Asterales | Artemisia sieversiana | Sieversian wormwood | 1068 | Art si 12 | Enolase | 50 kDa | Ninety subjects claiming allergy to Siversian wormwood pollen were tested and 12 were positive by IgE binding using ELISA and western blot to recombinanto protein | 2 | 2021-08-03 03:42:57 | 2021-08-09 20:11:29 | ||
| Plantae Eudikotyledons | Asterales | Artemisia sieversiana | Sieversian wormwood | 1119 | Art si 14 | Fructose bisphosphate aldolase | 38 kDa | In an IgE dot-blot, natural Art si 14 as well as recombinant Art si 14.0101, produced in E. coli, bound IgE from 10 of 20 sera (50%) from Artemisia pollen allergic patients (symptoms: allergic rhinitis and/or asthma; ImmunoCAP class >= 3 with A. vulgaris ImmunoCAP). Nine of the ten dot-blot-positive sera also bound both allergens in IgE Western blot. In an IgE-ELISA, 50 of 87 sera (57%) from Artemisia pollen allergic patients had IgE to rArt si 14.0101. IgE ELISA inhibitions with a pool of Art si 14-sensitized sera showed partial inhibition of IgE binding to A. sieversiana pollen extract by natural and recombinant Art si 14 as well as a high extent of cross-reactivity with Art an 14. In a BAT assay, 3 of 3 Art si 14-sensitized patients reacted with rArt si 14. | 38375932 | 2 | 2022-10-17 16:47:34 | 2024-09-18 18:12:06 | |
| Plantae Eudikotyledons | Asterales | Artemisia tridentata | Common sagebrush | 966 | Art t 1 | Defensin-like protein with polyproline rich domain, Art v 1-like | 24 to 26 kDa | Sera from 11 subjects with late summer rhinitis or conjunctivitis and with positive SPT to mugwort were demonstrated to cause positive IgE binding using western blot and ELISA to purified natural Art t 1, and basophil activation in four of four subjects sera. Unpublished so far | 2 | 2019-06-07 22:46:15 | 2025-08-25 17:08:04 | ||
| Plantae Eudikotyledons | Asterales | Artemisia vulgaris | Mugwort, wormwood | 89 | Art v 1 | Defensin-like protein linked to polyproline-rich region | 28 kDa | >70% of the individuals allergic to Artemisia vulgaris pollen had specific IgE in serum demonstrated by ELISA, and had positive skin prick tests in response to Art v 1. - All 18 patients allergic to mugwort pollen showed serum IgE binding to purified Art v 1 and rArt v 1 in immunoblot of mugwort pollen extract: medline 22309159 - At least 95% of sera from mugwort pollen-allergic patients contained IgE against highly glycosylated Art v 1. | 2395437 12475905 | 2 | 2003-04-14 12:00:00 | 2020-05-13 21:36:32 | |
| Plantae Eudikotyledons | Asterales | Artemisia vulgaris | Mugwort, wormwood | 90 | Art v 2 | Pathogenesis-related protein PR-1 | 20 kDa (35 kDa non-red) | In R(R)IE, purified Art v 2 bound IgE from 5 (33%) of 15 sera from patients with clinical allergy against mugwort pollen and from 13 (52%) of 25 sera from patients selected only on the basis of a RAST-class 4 against mugwort pollen. | 2233755 | 2 | 2003-04-17 12:00:00 | 2019-07-11 08:52:36 | |
| Plantae Eudikotyledons | Asterales | Artemisia vulgaris | Mugwort, wormwood | 91 | Art v 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 12 kDa | Of 17 patients studied, the 10 asymptomatic patients reacted only to a 9-kD LTP of both mugwort and peach in IgE immunoblotting, whereas the 7 patients with pollinosis reacted to other allergens. Conclusion, patients sensitized only to Art v 3 of mugwort do not present hay fever symptoms, and this sensitization is a consequence of the peach sensitization. | 12170274 | 2 | 2003-04-17 12:00:00 | 2025-04-10 18:12:30 | |
| Plantae Eudikotyledons | Asterales | Artemisia vulgaris | Mugwort, wormwood | 92 | Art v 4 | Profilin | 14 kDa | Thirty-six percent of the mugwort-allergic patients tested displayed IgE antibodies against natural and recombinant profilin. 3 out of 16 patients allergic to mugwort pollen showed serum IgE binding to Art v 4 on immunoblot of mugwort pollen extract. | 12530543 | 2 | 2003-04-17 12:00:00 | 2020-05-13 21:41:07 | |
| Plantae Eudikotyledons | Asterales | Artemisia vulgaris | Mugwort, wormwood | 93 | Art v 5 | Polcalcin | 10 kDa | 18588553 | 2 | 2006-11-03 12:00:00 | 2019-07-11 08:58:08 | ||
| Plantae Eudikotyledons | Asterales | Artemisia vulgaris | Mugwort, wormwood | 94 | Art v 6 | Pectate lyase | 44 kDa | 2 | 2006-11-03 12:00:00 | 2019-07-11 08:58:38 | |||
| Animalia Nematoda | Ascaridida | Ascaris lumbricoides | Common roundworm | 95 | Asc l 3 | Tropomyosin | 40 kDa | 54/85 individuals with allergic asthma upon exposure to A. lumbricoides had IgE in immunoblots directed to the natural Asc l 3 purified by affinity chromatography. | 1 | 2009-11-30 12:00:00 | 2019-07-11 22:59:46 | ||
| Animalia Nematoda | Ascaridida | Ascaris lumbricoides | Common roundworm | 987 | Asc l 5 | Al16, members of the SXP/RAL-2 protein family | 14 kDa | 13 of 26 subjects with Ascaris lumbricoides infection and allergy were positive by IgE binding to recombinant protein produced by cDNA clone. 81 non-infected people were negative. 3 of 5 subjects had positive basophil resonses to this protein, measured by CD203c positivity by flow cytometry. | Allergy, abstracts of EAACI meeting in Barcelona, abstract 13 in Allergy 70 (Supple 101), Manotas, M., Zakzuk, J., Coronado, S., Ahumada, V and Caraballo, L. | 1 | 2019-10-17 10:18:00 | 2025-08-25 17:12:53 | |
| Animalia Nematoda | Ascaridida | Ascaris lumbricoides | Common roundworm | 777 | Asc l 13 | Glutathione S-transferase (GST) | 23 kDa | 26 (90%) of 29 patients exposed to A. lumbricoides with positive CAP to A. lumbricoides showed IgE binding to purified natural Asc l 13 in ELISA. Of 12 patients tested by SPT with nAsc l 13, 5 (42%) reacted. The identity of the natural purified Asc l 13 was established by sequencing 73% of the protein by MS/MS. | 24223794 | 1 | 2014-09-08 12:00:00 | 2019-07-11 22:58:02 | |
| Animalia Nematoda | Ascaridida | Ascaris suum | Pig roundworm | 96 | Asc s 1 | 10 kDa | Passive cutaneous anaphylaxis with affinity purified Asc s 1 in rats | 2335378 | 1 | 2003-05-13 12:00:00 | 2019-07-11 23:04:15 | ||
| Animalia Nematoda | Ascaridida | Ascaris suum | Pig roundworm | 803 | Asc s 13 | Glutathione S-transferase | 23 kDa | 20 of 29 Ascaris ImmunoCAP positive subjects showed IgE binding to GST by ELISA; 12 of 91 non-asthmatic controls were positive by ELISA to GST in vitro IgE binding; 42 of 215 Asmthmatic subjects were positive to GST by ELISA; 3 of 10 asthmatics tested with recombinant GST by Skin Prick test were positive with at least 3mm diameter wheal | 24223794 | 1 | 2014-09-08 12:00:00 | 2019-07-11 23:04:42 | |
| Plantae Liliopsida (monocots) | Asparagales | Asparagus officinalis | Asparagus | 126 | Aspa o 1 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | Both purified nsLTP isoforms inhibited serum IgE-binding (pool of sera from patients with asparagus allergy) to asparagus extract up to 60% in CAP inhibition assay. Skin prick test responses (20 ug/ml) to LTP-1 were positive in 9 (50%) of 18 patients tested. | 12417890 | 1 | 2003-06-19 12:00:00 | 2025-04-10 18:12:45 | |
| Fungi Ascomycota | Eurotiales | Aspergillus flavus | Cereal mold | 120 | Asp fl 13 | Alkaline serine protease | 34 kDa | The results of the immunoblot analysis indicate that a 34-kD component that has high IgE-binding (63%) frequency is a major allergen of A. flavus. | 10474033 | 2 | 2003-08-21 12:00:00 | 2019-07-15 23:24:41 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 97 | Asp f 1 | Mitogillin family | 18 kDa | Of 13 patients with ABPA or asthma and with IgE Ab against A.fumigatus, 11 (85%) had IgE Abs against Asp f 1, as measured by RIA. 4 out of 5 patients with positive SPT to A.fumigatus gave positive SPT in response to Asp f 1 at 10(-2)-10(-6)ug/ml. | 2230656 | 2 | 2003-08-21 12:00:00 | 2019-07-11 23:07:47 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 106 | Asp f 2 | Pra1-related protein containing a HRXXH motif-containing metalloprotease domain | 37 kDa | Both native and recombinant Asp f 2 exhibited specific IgE binding with 10 allergic bronchopulmonary aspergillosis (ABPA) and 10 cystic fibrosis-ABPA patients in ELISA. However, patients with asthma and Aspergillus skin test reactivity but no evidence of ABPA only showed low levels of IgE antibody to Asp f 2 (see also medline 96197960. | 9784519 | 2 | 2003-08-21 12:00:00 | 2024-07-18 17:40:31 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 112 | Asp f 3 | Peroxysomal protein | 19 kDa | Of 89 individuals sensitized to A. fumigatus, 72% showed IgE binding to rAsp f 3, as detected by ELISA. | 9412580 | 2 | 2003-08-21 12:00:00 | 2019-07-11 23:08:55 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 114 | Asp f 4 | Protein of unknown function | 30 kDa | Of 24 patients with allergic bronchopulmonary aspergillosis (ABPA), 92% showed IgE binding to rAsp f 4 in ELISA. Among another patient population, 62% of the patients showed IgE binding. Of 16 asthmatics with immediate skin test reactivity to A.fumigatus, 0-18% showed IgE binding to rAsp f 4 | 10848921,9565354 | 2 | 2003-08-26 12:00:00 | 2024-07-18 17:42:26 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 115 | Asp f 5 | Metalloprotease | 40 kDa | Of 54 patients with allergic bronchopulmonary aspergillosis (ABPA), 50 (93%) showed IgE binding to r Asp f 5 in ELISA. Of 35 A.fumigatus-sensitized patients without ABPA, 26 (74%) showed IgE binding to rAsp f 5 | 9482698 | 2 | 2003-08-26 12:00:00 | 2019-07-11 23:10:28 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 116 | Asp f 6 | Mn superoxide dismutase | 26.5 kDa | Of 54 patients with allergic bronchopulmonary aspergillosis (ABPA), 30 (56%) showed IgE binding to r Asp f 6 in ELISA. Of 35 A.fumigatus-sensitized patients without ABPA, 0 (0%) showed IgE binding to rAsp f 6 | 9482698 | 2 | 2003-08-26 12:00:00 | 2019-07-11 23:11:44 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 117 | Asp f 7 | Expansin-like protein | 12 kDa | Of 54 patients with allergic bronchopulmonary aspergillosis (ABPA), 25 (46%) showed IgE binding to r Asp f 7 in ELISA. Of 35 A.fumigatus-sensitized patients without ABPA, 10 (29%) showed IgE binding to rAsp f 7 | 9482698 | 2 | 2003-08-26 12:00:00 | 2024-07-18 17:45:29 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 118 | Asp f 8 | Ribosomal protein P2 | 11 kDa | Asp f 8 reacted with IgE antibody in the sera of patients and showed skin prick test reactivity in ABPA patients. | 12444314 | 2 | 2003-08-26 12:00:00 | 2019-07-11 23:25:23 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 119 | Asp f 9 | Cell wall associated glycosidase Crf1 | 34 kDa | Of 54 patients with allergic bronchopulmonary aspergillosis (ABPA), 48 (89%) showed IgE binding to r Asp f 9 in ELISA. Of 35 A.fumigatus-sensitized patients without ABPA, 11 (31%) showed IgE binding to rAsp f 9 | 9482698 | 2 | 2003-08-26 12:00:00 | 2024-07-18 17:51:44 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 98 | Asp f 10 | Aspartate protease | 34 kDa | Of 54 patients with allergic bronchopulmonary aspergillosis (ABPA), 15 (28%) showed IgE binding to rAsp f 10 in ELISA. Of 35 A.fumigatus-sensitized patients without ABPA, 1 (3%) showed IgE binding to rAsp f 10 | 9482698 | 2 | 2003-08-26 12:00:00 | 2019-07-11 23:14:42 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 99 | Asp f 11 | Peptidyl-prolyl cis-trans isomerase, cyclophilin | 24 kDa | Of 30 A.fumigatus-sensitized patients, 27 (90%) showed IgE binding to rAsp f 11 in ELISA. rAsp f 11 induced a positive skin reaction in 4 patients with high specific IgE levels (>30 EU/ml) | 11753999 | 2 | 2003-08-26 12:00:00 | 2025-08-11 14:20:39 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 100 | Asp f 12 | Heat shock protein P90 | 90 kDa | IgE binding to r Asp f 12 on immunoblot (1 patient with allergic brochopulmonary aspergillosis tested) | 8491935 | 2 | 2003-08-26 12:00:00 | 2019-07-11 23:40:13 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 101 | Asp f 13 | Alkaline serine protease | 34 kDa | The study suggests that extracellular elastolytic protease is a significant virulence factor in invasive aspergillosis. | 8500876 | 2 | 2003-08-26 12:00:00 | 2019-07-11 23:40:47 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 102 | Asp f 15 | Cerato-platanin | 16 kDa | Asp f 13 | 2 | 2003-08-26 12:00:00 | 2024-07-18 17:54:01 | ||
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 103 | Asp f 16 | Cell wall associated glycosidase Crf1 | 43 kDa | Of 26 patients with allergic brochopulmonary aspergillosis (ABPA), 70% showed IgE binding to rAsp f 16 in ELISA. Apergillus skin test-positive asthmatics without ABPA did not show IgE binding. | 11422136 | 2 | 2003-08-26 12:00:00 | 2024-07-18 17:57:15 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 104 | Asp f 17 | Hydrophobic surface binding protein HsbA | 27 kDa | 2 | 2003-08-26 12:00:00 | 2024-07-18 18:05:08 | |||
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 105 | Asp f 18 | Vacuolar serine protease | 34 kDa | Of 19 asthmatic, A.fumigatus-sensitized patients, 15 (79%) showed serum IgE binding to 34 kD Asp f 18 (identified by N-terminal amino acid sequence analysis) on immunoblot. Of another 14 patients, 11 (79%) showed IgE binding to Asp f 18. | 11251631 | 2 | 2003-08-26 12:00:00 | 2019-07-11 23:44:13 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 1104 | Asp f 19 | Heat shock protein 70 kDa (Hsp70) | 69.4 kDa | Nine of 52 subjects with asthma and high IgE to Aspergillus fumigatus by ImmunoCAP to the source species extract. 41 negative IgE from neg. controls. | 38334146 | 2 | 2022-05-15 00:07:54 | 2024-09-20 17:48:06 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 107 | Asp f 22 | Enolase | 46 kDa | Sera from 7 (30%) of 23 Penicillium-sensitized asthmatic patients showed IgE binding to the 47 kD P.citrinum enolase. Of these 7 patients, 6 showed IgE binding to both natural Asp f 22 and rAsp f 22 on immunoblot. | 11979043 | 2 | 2003-08-26 12:00:00 | 2019-07-11 23:50:31 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 108 | Asp f 23 | L3 ribosomal protein | 44 kDa | 2 | 2006-02-26 12:00:00 | 2019-07-12 00:25:45 | |||
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 1105 | Asp f 24 | putative eukaryotic translation elongation factor 1 subunit EF1-beta | 34 kDa | Seven of 52 subjects with asthma and IgE to extract of the source organism by ImmunoCAP, as well as SPT to extract, were positive by Western Blot, ELISA and Dot blot to recombinant protein from E. coli expressed protein. 41 negative control subjects were negative. | 38334146 | 2 | 2022-05-15 00:25:37 | 2024-09-20 17:48:32 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 109 | Asp f 27 | Cyclophilin | 18 kDa | Of 40 individuals sensitized to A. fumigatus, 75% showed IgE binding to rAsp f 27, as detected by ELISA. | 16483252 | 2 | 2006-02-26 12:00:00 | 2019-07-11 23:52:07 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 110 | Asp f 28 | Thioredoxin | 13 kDa | Of 40 individuals suffering from ABPA and sensitized to A. fumigatus, 30% showed IgE binding to rAsp f 28, as detected by ELISA. | Submission to the?I.U.I.S. Allergen Nomenclature Sub-Committee | 2 | 2006-02-26 12:00:00 | 2019-07-12 00:32:11 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 111 | Asp f 29 | Thioredoxin | 13 kDa | Of 40 individuals suffering from ABPA and sensitized to A. fumigatus, 50% showed IgE binding to rAsp f 29, as detected by ELISA. | Submission to the?I.U.I.S. Allergen Nomenclature Sub-Committee | 2 | 2006-02-26 12:00:00 | 2019-07-12 00:32:34 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 113 | Asp f 34 | PhiA cell wall protein | 20 kDa | Of 40 individuals suffering from ABPA and sensitized to A. fumigatus, 93% showed IgE binding to rAsp f 34, as detected by ELISA. | 19416144 | 2 | 2007-06-05 12:00:00 | 2021-10-06 17:07:28 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 1106 | Asp f 35 | Cu-Zn Superoxide dismutase | 21 kDa | 14 of 52 subjects with asthma were positive by SPT with extract of Aspergillus fumigatus and positive by western blot, dot blot and ELISA to recombinant E. coli produced protein. 41 subjects without asthma were negative. | 38334146 | 2 | 2022-05-15 01:15:56 | 2025-08-25 18:01:57 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 1108 | Asp f 36 | Fructose-bisphosphate aldolase | 42 kDa | 17 of 52 subjects with asthma and SPT+ to extract of Aspergillus fumigatus were positive for IgE by western blot, dot blot and ELISA to E. coli produced protein. 41 subjects without asthma were negative. | 38334146 | 2 | 2022-05-15 01:53:17 | 2024-09-20 17:49:47 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 1107 | Asp f 37 | Malate dehydrogenase NAD-Dependent | 35 kDa | 15 subjects with asthma and SPT+ to Aspergillus fumigatus extract were positive by IgE to E. coli produced protein by western blot, dot blot and ELISA. 41 subjects without asthma were negative. | 38334146 | 2 | 2022-05-15 01:35:00 | 2024-09-20 17:50:16 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 1109 | Asp f 38 | Protein of unknown function | 25 kDa | Five of 52 subjects with asthma and SPT+ to extract of Aspergillus fumigatus and IgE positive by western blot, dot blot and ELISA to E. coli produced protein. 41 subjects without asthma were negative. | 38334146 | 2 | 2022-05-15 02:05:34 | 2024-09-20 17:50:54 | |
| Fungi Ascomycota | Eurotiales | Aspergillus fumigatus | Common mold | 1110 | Asp f 39 | FG-GAP repeat protein | 35 kDa | Five of 52 subjects with asthma and SPT+ to extract of Aspergillus fumigatus were positive in IgE binding to E. coli produced protein by western blot, dot blot and ELISA. 41 subjects without asthma were negative. | 38334146 | 2 | 2022-05-15 02:23:29 | 2025-04-30 16:06:38 | |
| Fungi Ascomycota | Eurotiales | Aspergillus niger | Black mold | 121 | Asp n 14 | Beta-xylosidase | 105 kDa | 11% of 171 tested bakers with workplace-related symptoms had specific IgE to xylanase on immunoblot. The main IgE-binding protein in the xylanase preparation, recognized in 7 of 8 xylanase-positive subjects, was a protein of about 105 kd, identified as Asp n 14. | 9723670 | 2 | 2003-08-26 12:00:00 | 2019-07-15 23:28:48 | |
| Fungi Ascomycota | Eurotiales | Aspergillus niger | Black mold | 122 | Asp n 18 | Vacuolar serine protease | 34 kDa | 2 | 2003-08-26 12:00:00 | 2019-07-15 23:27:36 | |||
| Fungi Ascomycota | Eurotiales | Aspergillus niger | Black mold | 123 | Asp n 25 | 3-phytase B | 66-100 kDa | 2 | 2006-02-26 12:00:00 | 2019-07-15 23:29:10 | |||
| Fungi Ascomycota | Eurotiales | Aspergillus oryzae | Rice mold | 124 | Asp o 13 | Alkaline serine protease | 34 kDa | Of 70 asthmatic patients, 17 had IgE Ab to A.oryzae. Of these 17 patients, 71% showed IgE to 34 kD Asp o 13 (identified by N-terminal amino acid sequence analysis) on immunoblot. | 9623506 | 2 | 2003-08-26 12:00:00 | 2019-07-15 23:32:55 | |
| Fungi Ascomycota | Eurotiales | Aspergillus oryzae | Rice mold | 125 | Asp o 21 | TAKA-amylase A | 53 kDa | 35% of symptomatic (Asthma + rhinitis) bakers were amylase +ve by SPT, 32% by IgE-EAST | 8087658 | 2 | 2003-08-26 12:00:00 | 2019-07-15 23:33:19 | |
| Fungi Ascomycota | Eurotiales | Aspergillus terreus | Common mold | 998 | Asp t 36 | Triosephosphate isomerase | 28 kDa | 15 of 15 subjects and none of 5 control serum donors IgE bound to the natural and recombinant protein. 68 of 260 subjects with airway allergy in the Kolkata area were positive by SPT to crude protein (extract?) used in tests. | 2 | 2019-12-21 01:30:27 | 2019-12-21 01:36:24 | ||
| Fungi Ascomycota | Eurotiales | Aspergillus versicolor | 721 | Asp v 13 | Extracellular alkaline serine protease | 43 kDa | 8 of 40 A. versicolor allergic individuals had IgE that reacted with natural purified Asp v 13 in ELISA. | 2 | 2011-04-07 12:00:00 | 2019-07-16 00:02:06 | |||
| Bacteria Bacillota | Bacillales | Bacillus subtilis | Hay bacillus | 1122 | Bac s 1 | Nattokinase (subtilisin-like serine protease) | 30 kDa | Eigth patients with IgE-mediated food allergy to natto (soybeans fermented with Bacillus subtilis subsp. natto) were tested. All patients had immediate allergic reactions after ingestion of natto as well as positive SPT with natto. Of these patients, 4/8 (50%) had IgE to a 30 kDa protein from natto as well as from an extract from cultured B. subtilis subsp. natto detected by IgE immunoblot. The protein was identified by immunoblot inhibition with commercially available nattokinase and by mass spectrometry. Moreover, all 4 sera reacted to nattokinase in ELISA. Three patients were also tested with nattokinase by SPT and showed a reaction to the protein. Purity of the purchased nattokinase was confirmed by mass spectrometry. | 36517353 | 1 | 2023-01-11 17:22:38 | 2023-01-11 17:31:24 | |
| Plantae Eudikotyledons | Ericales | Bertholletia excelsa | Brazil nut | 127 | Ber e 1 | 2S sulfur-rich seed storage albumin | 9 kDa | All 11 Brazil nut-allergic patients tested showed IgE binding to 9kD Ber e 1 on immunoblot of Brazil nut extract. - IgE from 8 of the 9 subjects allergic to Brazil nuts tested bound to purified Ber e 1 on immunoblot: medline 96175164 | 9847444 | 1 | 2003-06-24 12:00:00 | 2019-07-16 00:07:51 | |
| Plantae Eudikotyledons | Ericales | Bertholletia excelsa | Brazil nut | 128 | Ber e 2 | 11S globulin seed storage protein | 29 kDa | Beyer,K., Bardina,L., Grishina,G., Ashraf,A., Teuber,S.S., Niggemann,B. and Sampson,H.A. Identification of a new Brazil nut allergen – Ber e 2. Feb 2008. Volume 121, Issue 2, Supplement 1, Page S247. | 1 | 2006-11-03 12:00:00 | 2019-07-16 00:17:01 | ||
| Plantae Eudikotyledons | Caryophyllales | Beta vulgaris | Sugar beet | 135 | Beta v 1 | Che a 1/Ole e 1 homolgue | 17 kDa | 6/15 workers at a sugar beet seed producing station who were exposed to sugar beet pollen had work-related symptoms of allergy, positive SPTs to sugar beet pollen and IgE that bound to Beta v 1. | 18694503 | 2 | 2008-08-18 12:00:00 | 2019-07-16 01:33:08 | |
| Plantae Eudikotyledons | Caryophyllales | Beta vulgaris | Sugar beet | 136 | Beta v 2 | Profilin, pollen | 14 kDa | 6/15 workers at a sugar beet seed producing station who were exposed to sugar beet pollen had work-related symptoms of allergy, positive SPTs to sugar beet pollen and IgE that bound to Beta v 2. | 18694503 | 2 | 2008-08-18 12:00:00 | 2019-07-16 01:33:47 | |
| Plantae Eudikotyledons | Fagales | Betula verrucosa (Betula pendula) | European white birch | 129 | Bet v 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 17 kDa | Bet v 1 is responsible for IgE binding in more than 95% of birch pollen allergic patients | 6886253 | 2 | 2003-03-13 12:00:00 | 2019-07-16 00:30:20 | |
| Plantae Eudikotyledons | Fagales | Betula verrucosa (Betula pendula) | European white birch | 130 | Bet v 2 | Profilin | 15 kDa | Of 242 birch pollen-sensitive patients (from six European countries),54 (22%) were found to have IgE antibodies to rBet v 2 as assessed by CAP. - medline 91313403: IgE antibodies from allergic individuals bound to natural and recombinant Bet v 2. Bet v 2 induced histamine release from blood basophils of profilin-allergic individuals, but not of individuals sensitized to other plant allergens | 12218371 | 2 | 2003-03-18 12:00:00 | 2019-07-16 01:06:53 | |
| Plantae Eudikotyledons | Fagales | Betula verrucosa (Betula pendula) | European white birch | 131 | Bet v 3 | Polcalcin-like protein (4 EF-hand) | 24 kDa | Bet v III | approximately 10% of 120 pollen-allergic patients tested showed IgE binding to rBet v 3 on nitrocellulose filters. | 7520389 | 2 | 2003-03-18 12:00:00 | 2019-07-16 01:07:17 |
| Plantae Eudikotyledons | Fagales | Betula verrucosa (Betula pendula) | European white birch | 132 | Bet v 4 | Polcalcin | 7-8 kDa | Approximately 5% of birch pollen-allergic patients showed IgE binding to rBet v 4 in immunoblotting experiments. - In another study, rBet v 4 was recognized by 20% of birch pollen-allergic patients: medline: 98005106 | 9353329 | 2 | 2003-03-18 12:00:00 | 2019-07-16 01:08:37 | |
| Plantae Eudikotyledons | Fagales | Betula verrucosa (Betula pendula) | European white birch | 133 | Bet v 6 | Phenylcoumaran benzylic ether reductase | 35 kDa | Bet v 5 | On immunoblots recombinant Bet v 5 bound IgE from 9 (32%) of 28 sera from patients allergic to birch pollen with a CAP class of at least 3. | 9519865,10550744 | 2 | 2003-03-18 12:00:00 | 2026-04-20 15:05:35 |
| Plantae Eudikotyledons | Fagales | Betula verrucosa (Betula pendula) | European white birch | 134 | Bet v 7 | Cyclophilin | 18 kDa | On immunoblots up to 20.8% of birch pollen-allergic patients recognized Bet v 7. The clinical relevance of Bet v 7 was demonstrated by positive immediate-type skin testing on a patient allergic to birch pollen. | 10669849 | 2 | 2003-03-18 12:00:00 | 2019-07-16 01:20:02 | |
| Plantae Eudikotyledons | Fagales | Betula verrucosa (Betula pendula) | European white birch | 917 | Bet v 8 | Glutathione-S-transferase | 27 kDa | IgE binding by ELISA, positive for 29 of 217 SPT birch pollen allergic subjects (airway), using recombinant allergen. Three of three were positive by hRBL activation using recombinant allergen. | 25275548 | 2 | 2018-01-15 18:33:24 | 2025-05-07 17:13:39 | |
| Animalia Arthropoda | Blattodea | Blattella germanica | German cockroach | 137 | Bla g 1 | Nitrile specifier, microvilli-like protein with unknown function | 46 kDa | Serum from 17 of 22 (77%) patients with cockroach hypersensitivity identified IgE-binding to recombinant Bla g 1 on immunoblot - Of 106 CR allergic patients with asthma, 30.2% had detectable IgE Ab to purified Bla g 1, as measured by RIA. In 7 selected patients, Bla g 1 induced positive immediate skin reactions (>8x8-mm wheal) to allergen conc. 10(-3.5) µg/ml. | 9804858 | 2 | 2003-05-16 12:00:00 | 2025-08-25 16:32:45 | |
| Animalia Arthropoda | Blattodea | Blattella germanica | German cockroach | 138 | Bla g 2 | inactive aspartic protease | 36 kDa | Of 106 CR allergic patients with asthma, 57.6% had detectable IgE Ab to affinity purified Bla g 2, as measured by RIA. In 7 selected patients, Bla g 2 induced positive immediate skin reactions (>8x8-mm wheal) to allergen concentrations up to 10(-3) µg/ml. | 7642642 | 2 | 2003-05-16 12:00:00 | 2020-03-24 18:57:37 | |
| Animalia Arthropoda | Blattodea | Blattella germanica | German cockroach | 762 | Bla g 3 | Hemocyanin, Arylphorins/TO Arthropod hemocyanins | 78.9 kDa (by mass spectrometry) | 22% of 61 sera from cockroach-allergic adult subjects with a positive skin prick test to B. germanica extract had IgE that bound to recombinant Bla g 3.0101 (E. coli product) in ELISA. | 24468254 | 2 | 2012-09-26 12:00:00 | 2020-03-24 19:03:02 | |
| Animalia Arthropoda | Blattodea | Blattella germanica | German cockroach | 139 | Bla g 4 | Calycin, lipocalin | 21 kDa | Of 73 sera from CR-allergic patients (RAST >200 units/ml), 41% had IgE Ab to rBla g 4, as measured by RIA. In plaque immunoassay, 60% (47/73) of sera gave positive IgE antibody plaques to rBla g 4. Positive skin tests were obtained in 7 selected patients, using 10(-3)-10(-5) µg/ml rBla g 4 | 8537384 | 2 | 2003-05-16 12:00:00 | 2020-03-24 19:11:06 | |
| Animalia Arthropoda | Blattodea | Blattella germanica | German cockroach | 140 | Bla g 5 | Glutathione S-transferase (GST) class sigma | 23 kDa | IgE Ab binding to natural and recombinant Bla g 5 was found in 27/40 (67.5%) and 29/40 (72.5%) of sera from CR-allergic patients, as measured by RIA. 5 out of 7 CR-allergic patients tested showed a positive skin reaction (>8x8-mm wheal) to rBla g 5, at conc. of 10(-4)-10(-1) µg/ml | 9252418 | 2 | 2003-05-16 12:00:00 | 2024-09-12 19:00:02 | |
| Animalia Arthropoda | Blattodea | Blattella germanica | German cockroach | 141 | Bla g 6 | Troponin C | 21 kDa | 14% of the 104 allergic sera showed IgE binding to recombinant Bla g 6 using a fluorescent multiplex array system. | 16751002 | 2 | 2003-10-30 12:00:00 | 2019-07-17 00:58:36 | |
| Animalia Arthropoda | Blattodea | Blattella germanica | German cockroach | 142 | Bla g 7 | Tropomyosin | 33 kDa | ELISA showed a recombinant Bla g 7 sensitization rate of 16.2% to German cockroach allergic sera. | 14510726 | 2 | 2003-05-19 12:00:00 | 2020-03-24 19:15:07 | |
| Animalia Arthropoda | Blattodea | Blattella germanica | German cockroach | 143 | Bla g 8 | Myosin, light chain | 21 kDa | The data has not yet been published, but Anna Pomes indicates they did the same IgE binding tests at the same time and had 14% of subjects with IgE binding to this protein, as well as to Bla g 6. The data on Bla g 6 is in PMID 16751002. | 2 | 2006-02-25 12:00:00 | 2020-03-24 19:16:20 | ||
| Animalia Arthropoda | Blattodea | Blattella germanica | German cockroach | 890 | Bla g 9 | Arginine kinase | 40 kDa | Two studies including this data by A Pomés with 10 of 23 subjects (43.5%) who were positive by case history for airway allergy, and positive by SPT with extract of Blatella germanica having also positive IgE by ImmunoCAP using Picchia produced recombinant Bla g 9 as the target (not yet published). Study by Chuang et al., 2010 with more than 7 subjects from Taiwan (>34%) with allergy and cockroach specific IgE being clearly positive by solid-phased immunobinding with native protein. A third study by Dillon et al., PMID 26414909 identified Th2 epitopes using cells from allergic subjects. | 20960453 | 2 | 2017-01-14 10:27:01 | 2020-03-23 21:53:09 | |
| Animalia Arthropoda | Blattodea | Blattella germanica | German cockroach | 779 | Bla g 11 | Alpha-amylase | 57 kDa | 23689614 | 2 | 2013-07-17 12:00:00 | 2019-07-17 00:42:59 | ||
| Animalia Arthropoda | Blattodea | Blattella germanica | German cockroach | 1005 | Bla g 12 | Chitinase | 58 kDa | 23 subjects sensitized to cockroach based on IgE binding with ImmunoCAP with German cockroach at 0.35 kU/L, and with SPT of commercial cockroach extract with a wheal >3 mm or both. Seven of the 23 had positive IgE binding to recombinant protein by test-ImmunoCAP with >0.1 kU/liter to this protein. | 33643303 | 2 | 2020-02-26 22:19:36 | 2021-05-25 22:28:53 | |
| Animalia Arthropoda | Blattodea | Blattella germanica | German cockroach | 1186 | Bla g 24 | Glutathione S-transferase (GST) class delta (related to Per a 5) | 25 kDa | Sera from 68 cockroach-allergic patients (symptoms + SPT to P. americana extract) were tested by ELISA. Of those, 22 (32%) contained IgE to rBla g 24. Sera from five non-atopic donors did not bind to the allergen. | 41925067 | 2 | 2026-02-16 14:47:18 | 2026-04-16 12:49:22 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 144 | Blo t 1 | Cysteine protease | 39 kDa | rBlo t 1 was recognized by 13/21 (62%) of storage mite skin test-positive patient sera on immunoblot. | 12534546 | 2 | 2003-04-24 12:00:00 | 2019-07-18 06:55:22 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 150 | Blo t 2 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 14.5 kDa | 15/243 by ELISA with recombinant | 21332797 | 2 | 2006-11-05 12:00:00 | 2023-11-09 13:25:00 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 152 | Blo t 3 | Trypsin | 23.8 kDa | 10 mite-allergic, asthmatic patients had positive skin prick tests with rBlo t 3. In ELISA, 23 of 45 (51%) patients showed IgE binding to rBlo t 3. IgE titer was generally low. | 12708986 | 2 | 2003-04-29 12:00:00 | 2019-07-18 07:07:51 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 153 | Blo t 4 | Alpha-amylase | 56 kDa | Blo t 4 induced positive skin prick tests in 28% of 100 subjects. | 19033729 | 2 | 2003-10-28 12:00:00 | 2020-05-12 23:29:55 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 154 | Blo t 5 | Group 5/21 allergen | 14 kDa | Recombinant Blo t 5 reacted with 37 out of 83 (45%; region 1) or 11 out of 55 (20%; region 2) sera from mite-allergic patients in RIA, and induced positive immediate skin tests at 10(-3) to 1 microg/ml. - Of 49 sera from mite-allergic Malaysian children, 36 (73.5%) had IgE responses to rBlo t 5, as measured by ELISA. Of 45 patients tested, 14 (31.1%) had positive skin prick tests to rBlo t 5. | 9001334; 12642844 | 2 | 2003-04-29 12:00:00 | 2023-11-09 13:15:18 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 155 | Blo t 6 | Chymotrypsin | 25 kDa | Blo t 6 induced positive skin prick tests in 8% in 200 allergic subjects. Cheong N, Lee BW, Chua KY, unpublished. | 2 | 2003-04-29 12:00:00 | 2019-07-18 07:31:13 | ||
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 905 | Blo t 7 | Bactericidal permeability-increasing like protein | 25 kDa | Sera from eight of 33 subjects with case histories of airway allergy and with IgE to Blomia tropicalis, were positive in IgE binding to recombinant Blo t 7. | 2 | 2017-10-12 15:39:32 | 2019-07-18 07:33:24 | ||
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 786 | Blo t 8 | Glutathione S-transferase | 27 kDa | Five of 20 subjects of a cohort of healthy and asthmatic volunteers reacted positively in a skin prick test with the purifed natural Blo t 8. | 2 | 2014-01-09 12:00:00 | 2019-07-18 07:34:19 | ||
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 1148 | Blo t 9 | Trypsin-like serine protease | 27 kDa | Twenty-six mite-allergic children with allergic rhinitis and/or asthma and specific IgE to Blomia extract were tested. Of those, 7 (27%) had IgE to rBlo t 9.0101 (expressed in the cytoplasm of E. coli) as tested by ELISA. | 41242272 | 2 | 2024-03-04 18:02:13 | 2026-07-07 15:50:39 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 145 | Blo t 10 | Tropomyosin | 33 kDa | Of 35 mite-allergic children, 7 (20%) gave a positive reaction to rBlo t 10 in skin prick tests. In ELISA, 27 of 93 (29%) patients with allergic rhinitis showed IgE binding to rBlo t 10. | 12190660 | 2 | 2003-05-08 12:00:00 | 2019-07-18 06:59:23 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 146 | Blo t 11 | Paramyosin | 110 kDa | 33 (52%) out of 63 patients with IgE reactivity to crude B.tropicalis mite extract showed IgE binding to rBlo t 11 in dot blot immunoassay. | 11815735 | 2 | 2003-04-24 12:00:00 | 2019-07-18 23:14:12 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 147 | Blo t 12 | Peritrophin-A-like domain containing protein | 14 kDa | Bt11a | rBlo t 12 was bound by IgE in 16 of 32 sera from individuals with asthma with a positive RAST response to B. tropicalis | 8939156,19226278 | 2 | 2003-04-24 12:00:00 | 2023-11-09 13:11:54 |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 148 | Blo t 13 | Cytosolic fatty acid-binding protein | 14.8 kDa | Bt6 | Of 45 sera from patients allergic to B. tropicalis, 11% bound to rBlo t 13 in RAST. Preabsorption of a pool of 4 of these reactive sera with rBlo t 13 gave 16% inhibition of IgE binding to B. tropicalis extract | 9104789 | 2 | 2003-04-24 12:00:00 | 2023-11-09 13:13:01 |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 1142 | Blo t 16 | Gelsolin/villin | 55 kDa | Sera from 40 mite-allergic children with asthma and sIgE to Blomia tropicalis (ImmunoCAP) were tested. Of those 11 (28%) had IgE to recombinant Blo t 16.0101 as determined by ELISA. Four of ten sera tested by immunoblot reacted to the recombinant allergen. | 41242272 | 2 | 2024-01-22 15:30:07 | 2026-07-07 15:51:38 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 1134 | Blo t 18 | Chitinase-like protein (contains a C-terminal peritrophin-A-like domain) | 55 kDa | Sera from 26 mite-allergic patients with positive ImmunoCAP to Blomia tropicalis (CAP class >= 3) were tested by ELISA. Of those, 15 sera (58%) had IgE to recombinant Blo t 18.0101 expressed in E. coli (ELISA OD exceeding the mean OD + 3*SD of 17 non-allergic donors' sera). | 38061933 | 2 | 2023-11-28 18:50:09 | 2024-09-20 18:03:08 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 149 | Blo t 19 | Anti-microbial peptide homologue | 7 kDa | Recombinant Blo t 19 bound IgE in 10% of mite-allergic subjects | 12372994 | 2 | 2003-04-29 12:00:00 | 2019-07-18 23:02:23 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 151 | Blo t 21 | Group 5/21 allergen | 13 kDa | Blo t 5.02 | 40 of 43 adult patients with rhinitis had IgE binding to Blo t 21. SPT positive in many IgE positive subjects with mean wheal size of 6.3 mm. Not cross-reactive with Blo t 5 even though the prevalence of IgE positivity was essentially identical. | 17445876 | 2 | 2007-02-08 12:00:00 | 2023-11-09 13:14:50 |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 1137 | Blo t 24 | Ubiquinol-cytochrome c reductase binding protein; Cytochrome b-c1 complex subunit 7 | 14 kDa | Sera from 26 children with allergic asthma and positive ImmunoCAP to Blomia tropicalis were tested. Of those, 18 sera (69%) were positive in an IgE ELISA with recombinant Blo t 24.0101 expressed in E. coli. In an IgE immunoblot, 7 of 10 tested sera reacted with the recombinant allergen. | 41242272 | 2 | 2023-11-29 15:45:07 | 2026-07-07 15:52:28 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 1136 | Blo t 26 | Myosin light chain | 22 kDa | Sera from 26 mite-allergic patients with positive ImmunoCAP to Blomia tropicalis (CAP class >= 3) were tested by ELISA. Of those, 22 sera (85%) had IgE to recombinant Blo t 26.0101 expressed in E. coli (ELISA OD exceeding the mean OD + 3*SD of 17 non-allergic donors' sera). | 38061933 | 2 | 2023-11-28 19:19:05 | 2024-09-20 18:03:58 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 1143 | Blo t 27 | Serpin serine protease inhibitor | 44 kDa | Sera from 26 mite-allergic children with allergic rhinitis and/or asthma and sIgE to Blomia tropicalis (ImmunoCAP) were tested. Of those 5 (19%) had IgE to recombinant Blo t 27.0101 as determined by ELISA. Three of ten sera tested by immunoblot reacted to the recombinant allergen. | 41242272 | 2 | 2024-01-22 15:42:16 | 2026-07-07 15:53:37 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 1144 | Blo t 28 | Heat shock protein Hsp70 | 70 kDa | In an ELISA with sera from 26 mite-allergic children (allergic rhinitis and/or asthma, sIgE to Blomia), 5 (19%) had IgE to recombinant Blo t 28.0101 expressed in E. coli. | 41242272 | 2 | 2024-02-23 15:02:42 | 2026-07-07 15:54:19 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 1145 | Blo t 30 | Ferritin | 20 kDa | In an ELISA with sera from 26 mite-allergic children (allergic rhinitis and/or asthma, sIgE to Blomia), 7 (27%) had IgE to recombinant Blo t 30.0101 expressed in E. coli. | 41242272 | 2 | 2024-02-23 15:23:15 | 2026-07-07 15:55:03 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 1138 | Blo t 31 | Cofilin | 17 kDa | Sera from 26 children with allergic rhinitis or asthma and positive ImmunoCAP to Blomia tropicalis were tested. Of those, 7 sera (27%) were positive in an IgE ELISA with recombinant Blo t 31.0101 expressed in E. coli. In an IgE immunoblot, 5 of 11 tested sera (45%) reacted with the recombinant allergen. | 41242272 | 2 | 2023-11-29 17:52:19 | 2026-07-07 15:55:54 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 1139 | Blo t 32 | Inorganic pyrophosphatase | 34 kDa | Sera from 26 children with allergic asthma and positive ImmunoCAP to Blomia tropicalis were tested. Of those, 10 sera (38%) were positive in an IgE ELISA with recombinant Blo t 32.0101 expressed in E. coli. In an IgE immunoblot, 5 of 10 tested sera reacted with the recombinant allergen. | 41242272 | 2 | 2023-11-29 18:10:58 | 2026-07-07 15:56:29 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 1146 | Blo t 37 | Chitin binding protein (contains 2 peritrophin-A-like domains) | 19 kDa | In an ELISA with sera from 26 mite-allergic children (allergic rhinitis and/or asthma, sIgE to Blomia), 9 (35%) had IgE to recombinant Blo t 37.0101 expressed in E. coli. | 41242272 | 2 | 2024-02-23 15:51:14 | 2026-07-07 15:56:59 | |
| Animalia Arthropoda | Sarcoptiformes | Blomia tropicalis | Tropical house dust mite | 1135 | Blo t 41 | Putative chitin-binding protein (contains a peritrophin-A-like domain) | 14 kDa | Sera from 26 mite-allergic patients with positive ImmunoCAP to Blomia tropicalis (CAP class >= 3) were tested by ELISA. Of those, 7 sera (27%) had IgE to recombinant Blo t 41.0101 expressed in E. coli (ELISA OD exceeding the mean OD + 3*SD of 17 non-allergic donors' sera). | 38061933 (therein named pBlo t 23),38336314 | 2 | 2023-11-28 19:09:00 | 2025-10-22 18:43:28 | |
| Animalia Arthropoda | Hymenoptera | Bombus pennsylvanicus | Bumble bee | 156 | Bom p 1 | Phospholipase A2 | 16 kDa | IgE binding to purified Bom p 1 in RAST was found in 14 out of 17 bee-allergic patients tested medline 21549919: IgE binding in RAST (6 patients tested) | 8613638 | 4 | 2003-05-31 12:00:00 | 2019-07-18 23:27:33 | |
| Animalia Arthropoda | Hymenoptera | Bombus pennsylvanicus | Bumble bee | 157 | Bom p 4 | Protease | 27 kDa | Of 17 bee-allergic patients tested, 14 showed IgE binding to Bom p 4 in RAST. medline 21549919: IgE binding to Bom p 4 in RAST (in 3 out of 6 patients tested) | 8613638 | 4 | 2003-05-31 12:00:00 | 2019-07-18 23:28:16 | |
| Animalia Arthropoda | Hymenoptera | Bombus terrestris | Bumble bee | 158 | Bom t 1 | Phospholipase A2 | 16 kDa | IgE binding to Bom t 1 in RAST (6 patients tested) | 11692115 | 4 | 2003-05-31 12:00:00 | 2019-07-18 23:29:15 | |
| Animalia Arthropoda | Hymenoptera | Bombus terrestris | Bumble bee | 159 | Bom t 4 | Protease | 27 kDa | IgE binding to Bom t 4 in RAST (6 patients tested) | 11692115 | 4 | 2003-05-31 12:00:00 | 2019-07-18 23:29:47 | |
| Animalia Arthropoda | Lepidoptera | Bombyx mori | Silk moth | 670 | Bomb m 1 | Arginine kinase | 42 kDa | Sera from 10 subjects allergic to cocoons or pupae of silkworm were tested by ELISA using recombinant Bomb m 1 and found positive, while none of 3 controls had specific IgE binding to the protein. The protein is highly homologous to Arginine kinase from a number of allergenic organisms including Plodia, Periplaneta, Litopenaeus and Penaeus. However, cross-inhibition was only tested and found to exist for Periplaneta (American cockroach). While the Liu publication does not clearly state the allergenic source or exposure of their subjects, consumption of silkworm pupae is known to cause anaphylaxis, this it is a plausible food allergen. | 19339797 | 1 | 2010-02-11 12:00:00 | 2019-07-18 23:31:37 | |
| Animalia Arthropoda | Lepidoptera | Bombyx mori | Silk moth | 1060 | Bomb m 3 | Tropomyosin | 38 kDa | 8 of 5 subjects experiencing food allergy upon ingestion of silk worm pupae experience allergic reactions and had IgE binding to the recombinant protein by ELISA or RAST. | 28339033 | 1 | 2021-05-04 01:03:15 | 2021-05-04 01:13:22 | |
| Animalia Arthropoda | Lepidoptera | Bombyx mori | Silk moth | 1063 | Bomb m 4 | 30 kDa hemolypmh lipoprotein PBMHP-6 | 30 kDa | 17 of 17 subjects with reported food allergy upon consumption of pupae of silkworm were positive by IgE binding with ELISA using recombinant protein. Also by western blot | 35028994 | 1 | 2021-06-22 00:43:22 | 2024-09-25 17:19:33 | |
| Animalia Arthropoda | Lepidoptera | Bombyx mori | Silk moth | 1064 | Bomb m 5 | 30 kDa Lipoprotein 6 | 29 kDa | Five of nine subjects allergic to food consumption of silkworm pupae were skin test positive with natural purified protein, seven of nine were positive by IgE bdining in ELISA. | 1 | 2021-07-03 17:51:59 | 2024-09-25 17:23:33 | ||
| Animalia Arthropoda | Lepidoptera | Bombyx mori | Silk moth | 1083 | Bomb m 6 | Hemolymph lipoprotein 3 | 28 kDa | Six of nine subjects with food allergy to consumption of silkworm pupae were IgE positive to the natural purified protein of hemolymph | 37638798 | 1 | 2022-01-03 17:54:14 | 2024-09-23 13:46:06 | |
| Animalia Chordata | Cetartiodactyla | Bos domesticus (Bos taurus) | Domestic cattle | 160 | Bos d 2 | Lipocalin | 20 kDa | Ag3, BDA20 | >90% of cow allergic patients showed IgE binding in immunoblot and ELISA; nBos d 2 and rBos d 2 positive in ELISA inhibition and skin prick test. | 9647765 | 2 | 2003-02-05 12:00:00 | 2025-08-25 16:33:34 |
| Animalia Chordata | Cetartiodactyla | Bos domesticus (Bos taurus) | Domestic cattle | 161 | Bos d 3 | S100 calcium-binding protein A7 | 11 kDa | BDA11 | IgE of one cow-allergic patient showed binding with native and recombinant Bos d 3 on immunoblot | 7594639 | 2 | 2003-02-05 12:00:00 | 2023-05-15 15:48:14 |
| Animalia Chordata | Cetartiodactyla | Bos domesticus (Bos taurus) | Domestic cattle | 162 | Bos d 4 | Alpha-lactalbumin | 14.2 kDa | >90% of cowmilk allergic patients showed IgE binding to Bos d 4 in CRIE; >90% showed IgE binding to Bos d 4 in ELISA; 8 out of 19 patients showed IgE binding to Bos d 4 peptides. | 3485933 | 1 | 2003-02-05 12:00:00 | 2020-05-13 23:48:02 | |
| Animalia Chordata | Cetartiodactyla | Bos domesticus (Bos taurus) | Domestic cattle | 163 | Bos d 5 | Beta-lactoglobulin | 18.3 kDa | >90% of cowmilk allergic patients showed IgE binding to Bos d 5 in CRIE; >90% showed IgE binding in ELISA to Bos d 5 and Bos d 5 peptides. | 3485933 | 1 | 2003-02-05 12:00:00 | 2020-05-13 23:49:15 | |
| Animalia Chordata | Cetartiodactyla | Bos domesticus (Bos taurus) | Domestic cattle | 164 | Bos d 6 | Serum albumin | 67 kDa | >90% of cowmilk allergic patients showed IgE binding to Bos d 6 in CRIE | 3485933 | 1 | 2003-02-05 12:00:00 | 2019-07-19 01:06:39 | |
| Animalia Chordata | Cetartiodactyla | Bos domesticus (Bos taurus) | Domestic cattle | 165 | Bos d 7 | Immunoglobulin | 160 kDa | IgE binding of milk-allergic patients to Ig in CRIE. IgE binding to a 160-kDa band on immunoblot, identified as bovine IgG, was detected in raw beef in 83% (10/12) of beef-allergic subjects. | 3485933 | 1 | 2003-02-05 12:00:00 | 2020-05-13 23:51:00 | |
| Animalia Chordata | Cetartiodactyla | Bos domesticus (Bos taurus) | Domestic cattle | 166 | Bos d 8 | Caseins (for individual components see Bos d 9-Bos d 12) | 20-30 kDa | 58 of 92 (63%) milk-allergic children showed IgE binding to Bos d 8 in an enzyme immunoassay | 9531166 | 1 | 2003-02-05 12:00:00 | 2019-07-19 01:07:14 | |
| Animalia Chordata | Cetartiodactyla | Bos domesticus (Bos taurus) | Domestic cattle | 756 | Bos d 9 | alphaS1-casein | 23.6 kDa | 57 of 58 casein-sensitized milk-allergic children showed IgE binding to alphaS1-casein in an enzyme immunoassay | 9531166 | 1 | 2012-08-30 12:00:00 | 2019-07-19 08:43:04 | |
| Animalia Chordata | Cetartiodactyla | Bos domesticus (Bos taurus) | Domestic cattle | 757 | Bos d 10 | alphaS2-casein | 25.2 kDa | 55 of 58 casein-sensitized milk-allergic children showed IgE binding to alphaS2-casein in an enzyme immunoassay | 9531166 | 1 | 2012-08-30 12:00:00 | 2019-07-19 08:44:16 | |
| Animalia Chordata | Cetartiodactyla | Bos domesticus (Bos taurus) | Domestic cattle | 758 | Bos d 11 | beta-casein | 24 kDa | 53 of 58 casein-sensitized milk-allergic children showed IgE binding to beta-casein in an enzyme immunoassay | 9531166 | 1 | 2012-08-30 12:00:00 | 2019-07-19 08:44:00 | |
| Animalia Chordata | Cetartiodactyla | Bos domesticus (Bos taurus) | Domestic cattle | 759 | Bos d 12 | kappa-casein | 19 kDa | 53 of 58 casein-sensitized milk-allergic children showed IgE binding to kappa-casein in an enzyme immunoassay | 9531166 | 1 | 2012-08-30 12:00:00 | 2019-07-19 08:44:31 | |
| Animalia Chordata | Cetartiodactyla | Bos domesticus (Bos taurus) | Domestic cattle | 1011 | Bos d 13 | Myosin light chain | 21 kDa | Thirty-one allergic patients sensitized to beef (ImmunoCAP) were tested, of which 16 reported allergic symptoms after consumption of red meat. Nine subjects showed IgE binding to a 20 kDa protein in IgE immunoblots with cooked beef extract. When tested by ELISA with recombinant Bos d 13, 8/9 subjects (5 allergic and 3 sensitized) and 5/9 subjects (4 allergic and 1 sensitized) had IgE to Bos d 13.0101 and Bos d 13.0201, respectively. | 37173826 | 1 | 2020-03-25 17:24:23 | 2023-05-15 15:24:30 | |
| Plantae Eudikotyledons | Brassicales | Brassica juncea | Indian or oriental mustard | 167 | Bra j 1 | 2S albumin seed storage protein | 14 kDa | Bra j 1-E | Of 11 mustard-sensitive patients tested, 7 (64%) showed IgE binding on immunoblot to a synthetic peptide (13.8 kD) of the large chain of Bra j 1. | 7688955 | 1 | 2003-06-19 12:00:00 | 2019-07-19 01:19:31 |
| Plantae Eudikotyledons | Brassicales | Brassica napus | Rapeseed | 168 | Bra n 1 | 2S albumin seed storage protein, napin BnIII, napin-3 | 15 kDa | In ELISA approximately 80% of the patients had IgE to purified Bra n 1. In SPTs purified Bra n 1 caused positive reactions in all 6 children tested. | 16461144 | 1 | 2003-06-19 12:00:00 | 2025-08-25 16:34:49 | |
| Plantae Eudikotyledons | Brassicales | Brassica oleracea | Cabbage and others | 169 | Bra o 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | Skin prick test with purified Bra o 3 shoed positive results in 12 of 14 patients (86%) with cabbage immediate hypersensitivity. | 16751008 | 1 | 2006-10-13 12:00:00 | 2025-04-10 18:12:58 | |
| Plantae Eudikotyledons | Brassicales | Brassica rapa | Field mustard, turnip | 170 | Bra r 1 | 2S albumin, napins | 10-14 kDa | In ELISA, approximately 80% of the 72 patients had IgE binding to purified napin from turnip rape. The 72 patients have atopic dermatitis and clearly positive reactions to seeds of oilseed rape and turnip rape, or both on SPTs. | 16461144 | 1 | 2006-10-13 12:00:00 | 2019-07-19 09:02:37 | |
| Plantae Eudikotyledons | Brassicales | Brassica rapa | Field mustard, turnip | 171 | Bra r 2 | Prohevein homologue | 25 kDa | Of 60 natural rubber latex-sensitive patients, 51 (82%) showed IgE binding to purified Bra r 2 in ELISA. In 4 out of 6 patients tested purified Bra r 2 (100 ug/ml) induced a positive skin reaction. | 10400861 | 1 | 2003-06-19 12:00:00 | 2019-07-19 09:03:39 | |
| Plantae Eudikotyledons | Brassicales | Brassica rapa | Field mustard, turnip | 745 | Bra r 5 | Polcalcin | Bra r 1, Bra r 4 | 8616215 | 2 | 2012-07-12 12:00:00 | 2024-06-28 17:37:56 | ||
| Plantae Eudikotyledons | Rosales | Broussonetia papyrifera | Paper mulberry | 1158 | Bro p 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 12-15 kDa | In the study by Spillner and Hussain, sera from 81 pollen-allergic patients from Pakistan with symptoms during the paper mulberry flowering season and positive SPT to paper mulberry pollen extract were tested. Of those, 43 sera (53%) had IgE to purified nBro p 3. The allergen also activated basophils of a Bro p 3-sensitized individual. The study by Jiang and Meng recruited pollen-allergic patients from Western China with symptoms during the paper mulberry flowering season as well as positive SPT and sIgE (custom-made ImmunoCAP) to paper mulberry pollen extract. All 38 tested sera had IgE to a 10 kDa allergen in an immunoblot with Bro p extract. In ELISA, 32 (80%) and 31 (78%) of 40 sera had IgE to nBro p 3 and rBro p 3.0101, respectively. In SPT with nBro p 3, 6 of 7 patients were positive. | 23967755,40294488 | 2 | 2024-10-08 17:16:43 | 2025-04-29 16:17:10 | |
| Animalia Arthropoda | Decapoda | Callinectes bellicosus | Warrior swimming brown crab | 1051 | Cal b 2 | Arginine kinase | 40 kDa | Eight of 12 subjects with described food allergy to cooked crab were evaluated for IgE binding using western blot. There were 2 negative controls. Protein was isolated by ion exchange chromatograph and identified by MS. In addition, RNA was isolated from crab muscle and cDNA sequencing and the protein was determined also by MS. | 35131595 | 1 | 2021-02-26 04:26:11 | 2024-09-25 17:40:35 | |
| Fungi Ascomycota | Saccharomycetales | Candida albicans | Common yeast | 177 | Cand a 1 | Alcohol dehydrogenase | 40 kDa | Of 30 asthmatic patients with a positive skin test and RAST to C.albicans, 23 (77%) showed serum IgE binding to a 40 kD component on an immunoblot of C.albicans extract. - This 40 kD protein was cloned and identified as Cand a 1. IgE binding to both natural and rCand a 1 was demonstrated on immunoblot and in ELISA (medline 92136159). | 2665907 | 2 | 2003-09-01 12:00:00 | 2019-07-20 07:50:40 | |
| Fungi Ascomycota | Saccharomycetales | Candida albicans | Common yeast | 178 | Cand a 3 | Peroxysomal protein | 20 kDa | 14616127 | 2 | 2003-10-28 12:00:00 | 2020-05-14 17:46:13 | ||
| Fungi Ascomycota | Saccharomycetales | Candida boidinii | Yeast | 179 | Cand b 2 | Peroxisomal membrane protein A | 20 kDa | 89 patients sensitized to A. fumigatus displayed significantly higher levels of rCand b 2-specific IgE in their serum (mean value: 100 EU/ml; p LESSTHAN 0.005) than 11 control individuals without a history of atopy. | 9412580 | 2 | 2003-09-01 12:00:00 | 2019-07-20 07:53:32 | |
| Animalia Chordata | Carnivora | Canis familiaris (C. lupus familiaris) | Domestic dog | 172 | Can f 1 | Lipocalin | 23-25 kDa | Dog 1, Ag13 | > 90% of dogallergic patients show IgE binding in RAST; >90% of patients pos. in SPT; IgE a-Can f1/a-dogdander=70%; 15 out of 20 patients (75%) bind rCan f 1, and rCan f 1 gives cross-linking of IgE and histamine release from peripheral blood leucocytes in vitro. | 1863894 | 2 | 2003-02-05 12:00:00 | 2020-05-13 23:58:15 |
| Animalia Chordata | Carnivora | Canis familiaris (C. lupus familiaris) | Domestic dog | 173 | Can f 2 | Lipocalin | 19 (27) kDa | Dog 2 | 80% of dog allergic patients showed IgE binding in RAST; IgE a-Can f 2/a-dogdander =23%; 5 out of 20 patients (25%) showed IgE binding to rCan f 2, and rCan f 2 gave cross-linking of IgE and histamine release from peripheral blood leucocytes in vitro. | 2045611 | 2 | 2003-02-05 12:00:00 | 2025-08-25 16:36:11 |
| Animalia Chordata | Carnivora | Canis familiaris (C. lupus familiaris) | Domestic dog | 174 | Can f 3 | Serum albumin | 69 kDa | 35% of 110 dog allergic patients showed serum IgE binding to Can f 3 on immunoblot. | 7512102 | 2 | 2003-02-05 12:00:00 | 2019-07-19 09:16:41 | |
| Animalia Chordata | Carnivora | Canis familiaris (C. lupus familiaris) | Domestic dog | 175 | Can f 4 | Lipocalin | 16 kDa (non-red.), 18 kDa (red.) | 13 of 37 (35%) dog allergic patients' sera contained IgE to purified nCan f 4 as determined by ImmunoCAP. | 20545700 | 2 | 2004-04-25 12:00:00 | 2020-05-14 00:02:47 | |
| Animalia Chordata | Carnivora | Canis familiaris (C. lupus familiaris) | Domestic dog | 176 | Can f 5 | Arginine esterase, prostatic kallikrein | 28 kDa | 28 (76%) of 37 tested dog allergic subjects had IgE against purified natural Can f 5 as determined by ImmunoCAP. | 19135239 | 2 | 2008-12-03 12:00:00 | 2020-05-14 00:03:32 | |
| Animalia Chordata | Carnivora | Canis familiaris (C. lupus familiaris) | Domestic dog | 709 | Can f 6 | Lipocalin | 27 and 29 kDa | 22515174 | 2 | 2011-02-03 12:00:00 | 2024-07-09 18:00:52 | ||
| Animalia Chordata | Carnivora | Canis familiaris (C. lupus familiaris) | Domestic dog | 850 | Can f 7 | Epididymal Secretory Protein E1, or Niemann Pick type C2 protein | 16 kDa | 12 out of 71 patients sera tested positive by IgE binding | 2 | 2015-11-02 12:00:00 | 2019-07-20 07:22:20 | ||
| Animalia Chordata | Carnivora | Canis familiaris (C. lupus familiaris) | Domestic dog | 996 | Can f 8 | Cystatin | 14 kDa | 15 of 113 patients with IgE to dog proteins by ImmunoCAP were positive to recombinant full length protein by ELISA. | 34489229 | 2 | 2019-12-05 23:00:12 | 2022-05-17 16:09:32 | |
| Plantae Eudikotyledons | Rosales | Cannabis sativa | Indian hemp | 1048 | Can s 2 | Profilin | 14 kDa | Five of 32 patients from Belgium and Germany (2) were positive in IgE binding tests with recombinant Can s 2 protein coupled to cytometric bead array. IgE were from 0.35 to 65 kUA/L among the 5. Routes of exposure were mostly inhalation though 2 cases it was ingestion, also all reported cutaneous reactivity to Cannabis. Multiple exposure routes. | 33607338 | 2 | 2021-01-24 18:06:57 | 2024-10-04 16:03:35 | |
| Plantae Eudikotyledons | Rosales | Cannabis sativa | Indian hemp | 794 | Can s 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | Up to 72% of 25 Cannabis allergic patients reporting likely-anaphylaxis to Cannabis are Can s 3 sensitized testing by three diagnostic methods (BAT, sIgE, and SPT). | 30273677; 24954374 | 2 | 2015-02-05 12:00:00 | 2025-04-10 18:13:43 | |
| Plantae Eudikotyledons | Rosales | Cannabis sativa | Indian hemp | 1006 | Can s 4 | Oxygen evolving Enhancer Protein 2 | 27.3 kDa | A total of 118 subjects, 113 with immediate symptoms upon exposure by inhalation (113 and two upon ingestion to cannabis, 30 healthy controls adn 45 with individual pollen or nsLTP sensitization were tested for IgE binding. 8 bound to the recombinant protein by CBA test. Three were positive by basophil activation. Not published yet | 32298851 | 2 | 2020-02-28 17:09:02 | 2024-10-04 16:15:57 | |
| Plantae Eudikotyledons | Rosales | Cannabis sativa | Indian hemp | 1049 | Can s 5 | Pathogenesis-related protein PR-10, Bet v 1-related protein | 17.7 kDa | 35 of 45 subjects with allergy to Cannabis (n=25) and/or birch pollen (n=20) were positive in IgE binding tested by cytometric bead assay using recominant protein as the target. Also, 8 of 8 tested by Mast Cell Activation were positive using the same recombinant protein. Subjects also reportedly were positive in contact testing. | 33607338 | 2 | 2021-01-24 18:32:46 | 2024-10-04 16:09:25 | |
| Plantae Eudikotyledons | Rosales | Cannabis sativa | Indian hemp | 1133 | Can s 7 | Thaumatin-like protein | Three groups of Cannabis-exposed subjects were tested: 1. 60 Cannabis-allergic patients as confirmed by SPT and specific IgE to Cannabis. 2. 10 pollen-allergic patients without Cannabis allergy, 3. 5 healthy controls. In an ELISA with rCan s 7.0101 (fusion protein of maltose-biding protein with the preprotein of Can s 7.0101), 16/60 (27%) cannabis-allergic patients, 2/10 atopic controls and none of the healthy controls had IgE to rCan s 7. In a passive mast cell activation test with rCan s 7, cells sensitized with 4/5 sera from Can s 7-sensitized cannabis-allergic patients, none of 5 atopic control subjects' sera and 1 of 3 healthy control subjects' sera were activated. | 37984436 | 2 | 2023-11-08 12:38:11 | 2024-03-08 15:35:57 | ||
| Plantae Eudikotyledons | Solanales | Capsicum annuum | Chili, bell pepper | 180 | Cap a 1 | Osmotin-like protein (thaumatin-like protein) | 23 kDa | 21 out of 22 sera from patients with the mugwort-birch-celery-spice syndrome showed IgE binding to 23 kDa osmotin-like protein (identified by N-terminal sequence analysis) on immunoblot . | 9491227 | 1 | 2003-08-08 12:00:00 | 2019-07-20 07:55:33 | |
| Plantae Eudikotyledons | Solanales | Capsicum annuum | Chili, bell pepper | 181 | Cap a 2 | Profilin | 14 kDa | Of 10 patients with food allergy to bell peppers tested, 5 showed IgE binding to 14 kDa profilin (identified by N-terminal sequence analysis) on immunoblot. | 9652302 | 1 | 2003-08-08 12:00:00 | 2019-07-20 07:55:49 | |
| Plantae Eudikotyledons | Solanales | Capsicum annuum | Chili, bell pepper | 1061 | Cap a 7 | Gibberellin-regulated protein, snakin | 10 kDa reducing; 12 kDa non-reducing | One Japanese of five well characterized consumers with two episodes of anaphylaxis to consumption of chili pepper, Capsicum annuum, was positive by SPT, basophil activation test and oral food challenge. The only protein recognized by patient’s IgE (via peptidic epitopes) was a GRP and IgE reactivity was inhibited by the recombinant protein. This patient's IgE also bound to GRP of Japanese cedar pollen, peach, citrus and potato. | 35557497 | 1 | 2021-05-05 18:59:42 | 2023-11-02 18:47:38 | |
| Plantae Eudikotyledons | Brassicales | Carica papaya | Papaya | 913 | Cari p 1 | endo-polygalacturonase | 57 kDa | Allergy to fruit of papaya and to pollen of papaya in 7 out of 7 patients. Negative in 3 control patients by IgE binding of recombinant as well as natural extract. Basophil activiation was positive in 4 subjects with 30-70% histamine release. Published June 2018, Frontiers in Plant Science. | 29967633 | 1 | 2017-12-21 17:07:23 | 2020-05-13 18:27:30 | |
| Plantae Eudikotyledons | Brassicales | Carica papaya | Papaya | 1038 | Cari p 2 | Chymopapain; member of the papain-like cysteine protease (petidase C1) family | 28 kDa | Ten subjects allergic to ingestion of papaya fruit were tested with recombinant protein produced by a cDNA clone from EMBL accession X97789.1, Taylor et al., protein is in GEPEPT as CAA66378.1. The recombinant protein was characterized also with LC-MSMS on the N-terminus. The rProtein was used for SPT in patients with 3 of 3 testing positive. Also used in a humanized rat basophil leukemia assay and 6 sera were positive. | 1 | 2020-11-05 21:37:00 | 2022-05-10 18:43:00 | ||
| Plantae Eudikotyledons | Fagales | Carpinus betulus | Hornbeam | 182 | Car b 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 17 kDa | recombinant Car b 1 bound tree pollen-allergic patient serum IgE, as demonstrated by CRIE | 1603091 | 2 | 2003-03-20 12:00:00 | 2019-07-20 07:57:12 | |
| Animalia Arthropoda | Sarcoptiformes | Carpoglyphus lactis | Dried fruit mite | 1190 | Carp l 2 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 14 kDa | Sera from 20 patients with respiratory symptoms and/or atopic dermatitis and positive ImmunoCAP (class >= 3) to Der p or Der f were tested. Of those, 20 sera (100%) had IgE to rCarp l 2.0101 measured by ELISA. | 2 | 2026-05-21 18:43:57 | 2026-05-21 18:43:57 | ||
| Plantae Eudikotyledons | Fagales | Carya illinoinensis | Pecan | 183 | Car i 1 | 2S albumin seed storage protein | 16 kDa | 22 out of 28 pecan allergic patients (79%) showed IgE binding to recombinant Car i 1 on dot-blot. Sera from patients with a convincing history of pecan allergy and/or detectable pecan specific IgE were from Mount Sinai school of medicine. | 21395309 | 1 | 2009-12-07 12:00:00 | 2019-07-20 08:09:39 | |
| Plantae Eudikotyledons | Fagales | Carya illinoinensis | Pecan | 870 | Car i 2 | Vicilin-like seed storage protein; 7S globulin | 55 kDa | 24% of 25 DBPCFC nut allergic subjects had IgE binding to the 7S vicilin of pecan by immunoblots using extract of pecan nuts and cDNA. | 27128197 | 1 | 2016-05-04 12:00:00 | 2021-10-12 14:36:31 | |
| Plantae Eudikotyledons | Fagales | Carya illinoinensis | Pecan | 184 | Car i 4 | Legumin seed storage protein; 11S globulin | Subunit of hexameric protein: 55.4 kDa | 16 of 27 pecan allergic subjects had IgE binding to recombinant 11S legumin, by dot-blot, and binding was inhibited with Jug r 4 or Car i 4. | 21718052 | 1 | 2009-12-07 12:00:00 | 2021-10-12 14:36:58 | |
| Plantae Eudikotyledons | Fagales | Castanea sativa | Chestnut | 185 | Cas s 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 22 kDa | 8 out of 8 patients suffering from tree pollen allergy showed serum IgE binding to purified Cas s 1 on immunoblot. Purified Cas s 1 was capable to induce IgE-mediated histamine-release in one patient tested. | 7504464 | 2 | 2003-03-20 12:00:00 | 2019-07-20 08:14:46 | |
| Plantae Eudikotyledons | Fagales | Castanea sativa | Chestnut | 186 | Cas s 5 | Chitinase class I | no information found | 1 | 2003-03-20 12:00:00 | 2021-10-12 14:40:11 | |||
| Plantae Eudikotyledons | Fagales | Castanea sativa | Chestnut | 187 | Cas s 8 | Non-specific lipid transfer protein type 1 (nsLTP1) | 12-13 kDa (non-red), 9 kDa (red) | Significant specific IgE levels to the puri?ed Cas s 8 were found in 7 (58%) of 12 allergic sera by means of ELISA and 6 (66%) of 9 patients by means of SPT. | 10998016, 16950291 | 1 | 2003-03-20 12:00:00 | 2025-04-10 18:13:56 | |
| Plantae Eudikotyledons | Fagales | Castanea sativa | Chestnut | 666 | Cas s 9 | Cytosolic class I small heat shock protein; Hsp20 | 17 kDa | 1 | 2010-01-25 12:00:00 | 2021-10-12 14:41:04 | |||
| Plantae Eudikotyledons | Gentianales | Catharanthus roseus | Rosy periwinkle | 188 | Cat r 1 | Cyclophilin | 18 kDa | Fifteen subjects from India, all skin prick test positive to extract of Rosy periwinkle (Catharanthus roseus), showed IgE binding to an 18 kDa protein in the extract of pollen. Some showed IgE binding to other proteins. IgE binding using a pool of 5 subjects showed maximum inhibition with recombinant Cat r 1.0101 (cyclophilin), and partial inhibition with recombinant Mala s 6 and Asp f 11. Humanized RBL assay showed activation with sera from five subjects having at least 10% specific release of beta-hexoxaminidase. | 24939849 | 2 | 2006-11-03 12:00:00 | 2019-07-30 07:51:40 | |
| Animalia Chordata | Rodentia | Cavia porcellus | Guinea pig | 189 | Cav p 1 | Lipocalin | 20 kDa | 28/40 sera (70%) of C.porcellus-sensitized patients showed IgE binding to Cav p 1 in immunoblot of hair extract; 34/40 in immunoblot of urine | 11972481 | 2 | 2003-02-05 12:00:00 | 2020-10-16 12:05:45 | |
| Animalia Chordata | Rodentia | Cavia porcellus | Guinea pig | 190 | Cav p 2 | Lipocalin | 17 kDa | 65% of 26 individuals with guinea pig allergy and positive CAPs to guinea pig epithelium had IgE that reacted in immunoblot and ELISA with the recombinant Cav p 2.0101 produced in E. coli Rosetta-gami cells. | 21518038 | 2 | 2006-02-25 12:00:00 | 2020-05-15 00:20:44 | |
| Animalia Chordata | Rodentia | Cavia porcellus | Guinea pig | 191 | Cav p 3 | Lipocalin | 18 kDa | 54% of 26 individuals with guinea pig allergy and positive CAPs to guinea pig epithelium had IgE that reacted in immunoblot and ELISA with the recombinant Cav p 3.0101 produced in E. coli Rosetta-gami cells. | 21518038 | 2 | 2009-09-28 12:00:00 | 2020-05-15 00:22:19 | |
| Animalia Chordata | Rodentia | Cavia porcellus | Guinea pig | 765 | Cav p 4 | Serum albumin | 66 kDa | The purified natural Cav p 4 bound IgE from 10/19 Guinea pig allergic individuals in ELISA. | 21518038 | 2 | 2012-12-20 12:00:00 | 2020-05-15 00:25:10 | |
| Animalia Chordata | Rodentia | Cavia porcellus | Guinea pig | 766 | Cav p 6 | Lipocalin | 18 kDa | Recombinant Cav p 6.0101, produced in E. coli, bound IgE from sera of 17/26 Guniea pig allergic individuals in ELISA. | 33797108 | 2 | 2012-12-20 12:00:00 | 2022-05-17 15:31:21 | |
| Plantae Pinopsida | Cupressales | Chamaecyparis obtusa | Japanese cypress | 193 | Cha o 1 | Pectate lyase | 47 kDa | 97.5% of 40 patients tested with pollinosis caused by C.obtusa, showed serum IgE binding to Cha o 1 in AlaSTAT. | 10486272 | 2 | 2003-03-27 12:00:00 | 2019-07-31 00:21:02 | |
| Plantae Pinopsida | Cupressales | Chamaecyparis obtusa | Japanese cypress | 194 | Cha o 2 | Polygalacturonase | 45 kDa | 33 out of 40 sera from patients with pollinosis caused by C. obtusa (82.5%), showed IgE binding to Cha o 2 in AlaSTAT - Of 32 serum samples from patients with Japanese cedar pollinosis, 27 (84.4%) showed IgE binding to purified Cha o 2 in RAST: medline 20183498 | 10486272 | 2 | 2003-03-27 12:00:00 | 2019-07-31 00:14:30 | |
| Plantae Pinopsida | Cupressales | Chamaecyparis obtusa | Japanese cypress | 843 | Cha o 3 | Cellulase (glycosyl hydrolase) | 63kDa | Fourteen of 16 Japanese pollen allergic subjects showed IgE binding to the pure protein in ELISA. Three of four had basophil activation (CD203c) positivity. All of these subjects were RAST class >2 positive. The 2016 publication in JACI demonstrates T cell reactivity as well as basophil activation. | 27237746 | 2 | 2015-08-25 12:00:00 | 2019-07-31 00:15:30 | |
| Animalia Arthropoda | Decapoda | Charybdis feriata | Crucifix crab | 192 | Cha f 1 | Tropomyosin | 34 kDa | All 10 crab-allergic patients showed IgE binding to rCha f 1 on immunoblot. IgE binding to crab extract on immunoblot was inhibited by preincubation of these sera with rCha f 1. | 9819304 | 1 | 2003-06-19 12:00:00 | 2019-07-30 23:50:30 | |
| Animalia Arthropoda | Decapoda | Charybdis feriata | Crucifix crab | 1149 | Cha f 10 | Fructose bisphosphate aldolase | 41 kDa | 99 sera from shellfish-allergic patients, as diagnosed by convincing history of allergic reactions after shellfish ingestion, positive SPT with shellfish extract mix and crab ImmunoCAP > 0.7 kUA/L, were tested. Of those, 13 sera (13%) had IgE to recombinant Cha f 10.0101 as measured by ELISA. | 1 | 2024-05-17 17:19:07 | 2024-09-17 18:37:22 | ||
| Plantae Eudikotyledons | Caryophyllales | Chenopodium album | Lamb's quarters, white goosefoot | 195 | Che a 1 | Ole e 1 homologue | 17 kDa | 77% of sera from patients allergic to chenopod pollen were reactive to Che a 1. | 11893853 | 2 | 2006-11-03 12:00:00 | 2019-07-31 00:23:03 | |
| Plantae Eudikotyledons | Caryophyllales | Chenopodium album | Lamb's quarters, white goosefoot | 196 | Che a 2 | Profilin | 14 kDa | Che a 2 (profilin) exhibited a prevalence of 55% in patients (n=104) hypersensitive to chenopod pollen. | 15208604 | 2 | 2006-11-03 12:00:00 | 2019-07-31 00:27:04 | |
| Plantae Eudikotyledons | Caryophyllales | Chenopodium album | Lamb's quarters, white goosefoot | 197 | Che a 3 | Polcalcin | 10 kDa | Purified Che a 3 (polcalcin) exhibited a prevalence 46% in patients (n=104) hypersensitive to chenopod pollen. | 15208604 | 2 | 2006-11-03 12:00:00 | 2019-07-31 00:28:22 | |
| Animalia Arthropoda | Diptera | Chironomus kiiensis | Midge | 198 | Chi k 10 | Tropomyosin | 32.5 kDa | Specific IgE antibodies reacting to recombinant tropomyosin expressed in E. Coli were detected in 17 (81%) of 21 patients who were skin test positive to C. kiiensis crude extracts. | 15013982 | 4 | 2003-05-20 12:00:00 | 2019-07-31 01:23:56 | |
| Animalia Arthropoda | Diptera | Chironomus thummi thummi | Midge | 199 | Chi t 1 | Hemoglobin, component III/IV | 16 kDa | Chi t I | Of 86 subjects with IgE against C.thummi thummi larvae, 76 had IgE against Chi t I, which comprises 12 homologous hemoglobins (Chi t 1-9). 56 of these 76 people were symptomatic. Chi t I induced histamine release in basophils of all 20 patients tested, and acute rhinitis and/or asthmatic reactions in all 25 patients tested in inhalation challenge test. - Of 15 patients allergic to C.thummi Thummi all had IgE against Chi t 1.01. 13 patients reacted with peptide 80-100 in ELISA: medline 2108351 - Of 15 C.thummi thummi-sensitized patients, all showed IgE binding to Chi t 1.02 in ELISA: medline 21083518. | 1701849 | 2 | 2003-05-20 12:00:00 | 2019-07-31 07:36:41 |
| Animalia Arthropoda | Diptera | Chironomus thummi thummi | Midge | 200 | Chi t 2 | Hemoglobin, component I/IA | 16 kDa | Chi t I | Of 86 subjects with IgE against C.thummi thummi larvae, 76 had IgE against Chi t I, which comprises 12 homologous hemoglobins (Chi t 1-9). 56 of these 76 people were symptomatic. Chi t I induced histamine release in basophils of all 20 patients tested, and acute rhinitis and/or asthmatic reactions in all 25 patients tested in inhalation challenge test. | 1701849 | 2 | 2003-05-22 12:00:00 | 2019-07-31 07:38:17 |
| Animalia Arthropoda | Diptera | Chironomus thummi thummi | Midge | 201 | Chi t 3 | Hemoglobin, components II-beta, VI, VII, VIII, IX | 16 kDa | Chi t I; Chi t 5, Chi t 6, Chi t 7, Chi t 8 | Of 86 subjects with IgE against C.thummi thummi larvae, 76 had IgE against Chi t I, which comprises 12 homologous hemoglobins (Chi t 1-9). 56 of these 76 people were symptomatic. Chi t I induced histamine release in basophils of all 20 patients tested, and acute rhinitis and/or asthmatic reactions in all 25 patients tested in inhalation challenge test. | 1701849 | 2 | 2003-05-22 12:00:00 | 2019-07-31 07:39:43 |
| Animalia Arthropoda | Diptera | Chironomus thummi thummi | Midge | 202 | Chi t 4 | Hemoglobin, component IIIA | 16 kDa | Chi t I | Of 86 subjects with IgE against C.thummi thummi larvae, 76 had IgE against Chi t I, which comprises 12 homologous hemoglobins (Chi t 1-9). 56 of these 76 people were symptomatic. Chi t I induced histamine release in basophils of all 20 patients tested, and acute rhinitis and/or asthmatic reactions in all 25 patients tested in inhalation challenge test. | 1701849 | 2 | 2003-05-22 12:00:00 | 2019-07-31 07:42:32 |
| Animalia Arthropoda | Diptera | Chironomus thummi thummi | Midge | 203 | Chi t 5 | renamed to Chi t 3.0201; designation not available for future submissions | 2 | 2003-05-22 12:00:00 | 2019-07-31 07:45:48 | ||||
| Animalia Arthropoda | Diptera | Chironomus thummi thummi | Midge | 204 | Chi t 6 | renamed to Chi t 3.03 and Chi t 3.04; designation not avbailable for future submissions | 2 | 2003-05-22 12:00:00 | 2019-07-31 07:46:42 | ||||
| Animalia Arthropoda | Diptera | Chironomus thummi thummi | Midge | 205 | Chi t 7 | renamed to Chi t 3.05-Chi t 3.08; designation not available for future submissions | 2 | 2003-05-22 12:00:00 | 2019-07-31 07:47:00 | ||||
| Animalia Arthropoda | Diptera | Chironomus thummi thummi | Midge | 206 | Chi t 8 | renamed to Chi t 3.09; designation not available for future submissions | 2 | 2003-05-22 12:00:00 | 2019-07-31 07:47:09 | ||||
| Animalia Arthropoda | Diptera | Chironomus thummi thummi | Midge | 207 | Chi t 9 | Hemoglobin, component X | 16 kDa | Chi t I | Of 86 subjects with IgE against C.thummi thummi larvae, 76 had IgE against Chi t I, which comprises 12 homologous hemoglobins (Chi t 1-9). 56 of these 76 people were symptomatic. Chi t I induced histamine release in basophils of all 20 patients tested, and acute rhinitis and/or asthmatic reactions in all 25 patients tested in inhalation challenge test. | 1701849 | 2 | 2003-05-22 12:00:00 | 2019-07-31 07:47:24 |
| Animalia Arthropoda | Sarcoptiformes | Chortoglyphus arcuatus | Storage mite | 1191 | Cho a 2 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 14 kDa | Sera from 20 patients with respiratory symptoms and/or atopic dermatitis and positive ImmunoCAP (class >= 3) to Der p or Der f were tested. Of those, 14 sera (70%) had IgE to rCho a 2.0101 measured by ELISA. | 2 | 2026-05-21 18:51:20 | 2026-05-21 18:51:20 | ||
| Animalia Arthropoda | Sarcoptiformes | Chortoglyphus arcuatus | Storage mite | 826 | Cho a 10 | Tropomyosin | 42 kDa | 13 of 20 allergy patients with IgE binding to other tropomyosins (Der p 10, Pen m 1, Ani s 3 and Bla g 7) showed light to heavy IgE binding to recombinant His-tagged Cho a 10 on reducing immunoblot, with 1:2 diluted sera. | 2 | 2015-04-24 12:00:00 | 2019-07-31 07:52:36 | ||
| Plantae Eudikotyledons | Fabales | Cicer arietinum | Chickpea | 1004 | Cic a 1 | Late embryogenesis abundant protein family 4; ECP63-like | 42 kDa | 31 of 36 people with clinical history of allergy to consumption of chickpea in Spain, were tested by SPT using commercial chickpea extract. 22 of 35 were positive to chickpea ImmunoCAP. 8 of 34 subjects were positive by IgE western blots to this protein that was expressed as a recombinant from a cDNA. | 1 | 2020-02-25 22:46:58 | 2025-07-02 16:10:03 | ||
| Plantae Eudikotyledons | Cucurbitales | Citrullus lanatus | Watermelon | 883 | Citr l 2 | Profilin | 14 kDa | 17 watermelon allergic subjects, all with pollen allergy also, all claimed OAS and were SPT positive. Inhibition of IgE binding with recombinant and native profilin was very good. 1 patient was tested by Basophil test and was positive | 20484919 | 1 | 2016-11-21 17:52:19 | 2016-11-22 00:55:54 | |
| Plantae Eudikotyledons | Sapindales | Citrus limon | Lemon | 208 | Cit l 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9.6 kDa (MALDI-TOF MS) | Of the 27 sera analyzed, specific IgE to the purified allergens was found in 54% for nCit l 3, 48% for nCit s 3, 46% for rCit s 3 and 37% for rPru p 3. | 15947476 | 1 | 2004-10-17 12:00:00 | 2025-04-10 18:27:55 | |
| Plantae Eudikotyledons | Sapindales | Citrus reticulata | Tangerine | 209 | Cit r 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | 1 | 2007-02-08 12:00:00 | 2025-04-10 18:14:34 | |||
| Plantae Eudikotyledons | Sapindales | Citrus sinensis | Sweet orange | 210 | Cit s 1 | Germin-like protein | 23 kDa | 22 of 23 (78%) orange allergic subjects had IgE binding to Cit s 1 on immunoblots. The 23 subjects were confirmed by DBPCFC for clinical symptoms to orange. | 16521162 | 1 | 2004-10-17 12:00:00 | 2019-07-31 19:12:11 | |
| Plantae Eudikotyledons | Sapindales | Citrus sinensis | Sweet orange | 211 | Cit s 2 | Profilin | 14 kDa | 18 of 23 (96%) orange allergic subjects had IgE binding to Cit s 2 on immunoblots. The 23 subjects were confirmed by DBPCFC for clinical symptoms to orange. | 16521162 | 1 | 2004-10-17 12:00:00 | 2019-07-31 19:12:40 | |
| Plantae Eudikotyledons | Sapindales | Citrus sinensis | Sweet orange | 212 | Cit s 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9.46 kDa (MALDI-TOF MS) | 1 | 2004-10-17 12:00:00 | 2025-04-10 18:28:14 | |||
| Plantae Eudikotyledons | Sapindales | Citrus sinensis | Sweet orange | 875 | Cit s 7 | Gibberellin regulated protein, peamaclein | 8 kDa | Patients defined by clinical history (7) and IgE binding (4 of 7) and/or skin prick tests (4 of 4) and/or basophil activation (4 of 4) | 30099793 | 1 | 2016-06-22 12:00:00 | 2024-09-13 17:12:54 | |
| Fungi Ascomycota | Capnodiales | Cladosporium cladosporioides | 213 | Cla c 9 | Vacuolar serine protease | 36 kDa | 41 out of 74 sera (55%) showed IgE binding against the 36 kDa Cla c 9 on immunoblot. The 74 sera were collected from subjects with bronchial asthma who had positive IgE reactivity against crude C. cladosporioides extracts. | 18362473 | 2 | 2009-09-28 12:00:00 | 2019-07-31 19:44:39 | ||
| Fungi Ascomycota | Capnodiales | Cladosporium cladosporioides | 689 | Cla c 14 | Transaldolase | 36.5 kDa | 10 of 26 C. cladosporioides allergic patients had serum IgE that reacted with the purified recombinant Cla c 14.0101 in immunoblots. | 21488999 | 2 | 2010-07-29 12:00:00 | 2019-07-31 19:19:29 | ||
| Fungi Ascomycota | Capnodiales | Cladosporium herbarum | Fungus of plants | 216 | Cla h 2 | 23 kDa | Ag54 | Of 35 C.herbarum-sensitized patients tested, 7 (20%) showed IgE binding to Ag-54 in CRIE (medline 79172270). Later this allergen was purified by gelfiltration (peak fraction 25 kD) and showed IgE binding in RAST (medline 79215369). - Of 62 C.herbarum-sensitized patients (positive immunoblot of C.herbarum), 43% showed IgE binding to purified Cla h 2 on immunoblot: medline 95337840 | 572347 | 2 | 2009-09-28 12:00:00 | 2019-08-01 00:01:09 | |
| Fungi Ascomycota | Capnodiales | Cladosporium herbarum | Fungus of plants | 217 | Cla h 5 | Acid ribosomal protein P2 | 11 kDa | Cla h 4 | Of 62 C.herbarum-sensitized patients (positive immunoblot of C.herbarum extract), 22% showed IgE binding to Cla h 4 on immunoblot (see also medline 95337840). | 7898496 | 2 | 2009-09-28 12:00:00 | 2019-07-31 23:20:33 |
| Fungi Ascomycota | Capnodiales | Cladosporium herbarum | Fungus of plants | 218 | Cla h 6 | Enolase | 46 kDa | Of 62 C.herbarium-sensitized patients (positive immunoblot of C.herbarum extract), 20% showed IgE binding to Cla h 6 on immunoblot (see also medline 95337840). - IgE epitope mapping: medline 20534817 | 7898496 | 2 | 2009-09-28 12:00:00 | 2019-07-31 23:21:21 | |
| Fungi Ascomycota | Capnodiales | Cladosporium herbarum | Fungus of plants | 219 | Cla h 7 | YCP4 protein | 22 kDa | Cla h 5 | Of 62 C.herbarum-sensitized patients (positive immunoblot of C.herbarum extract), 22% showed IgE binding to Cla h 7 on immunoblot (see also medline 95337840) | 7898496 | 2 | 2009-09-28 12:00:00 | 2019-07-31 23:21:53 |
| Fungi Ascomycota | Capnodiales | Cladosporium herbarum | Fungus of plants | 220 | Cla h 8 | Mannitol dehydrogenase | 28 kDa | The recombinant protein bound IgE from sera of 57% of C. herbarum-sensitzed patients (N=21) and elicited reactions in skin-prick tests. | 16608840 | 2 | 2009-09-28 12:00:00 | 2019-07-31 23:22:38 | |
| Fungi Ascomycota | Capnodiales | Cladosporium herbarum | Fungus of plants | 221 | Cla h 9 | Vacuolar serine protease | 45 kDa on SDS-PAGE | 17 out of 110 C. herbarum allergic sera (15.5%) reacted with recombinant Cla h 9 on immunoblot. | 19162325 | 2 | 2009-09-28 12:00:00 | 2019-07-31 23:31:34 | |
| Fungi Ascomycota | Capnodiales | Cladosporium herbarum | Fungus of plants | 214 | Cla h 10 | Aldehyde dehydrogenase | 53 kDa | Cla h 3 | Of 62 C.herbarum-sensitized patients (positive immunoblot of C.herbarum extract), 36% showed IgE binding to Cla h 3 on immunoblot (see also medline 95337840) | 7898496 | 2 | 2009-09-28 12:00:00 | 2019-07-31 23:17:43 |
| Fungi Ascomycota | Capnodiales | Cladosporium herbarum | Fungus of plants | 215 | Cla h 12 | Acid ribosomal protein P1 | 11 kDa | 2 | 2009-09-28 12:00:00 | 2019-07-31 23:31:57 | |||
| Animalia Chordata | Clupeiformes | Clupea harengus | Atlantic herring | 222 | Clu h 1 | Beta-parvalbumin | 12 kDa | Five of 11 fish allergic subjects showed IgE binding to Clu h 1.0101 by immunoblot. | 23763969 | 1 | 2009-12-30 12:00:00 | 2020-05-14 22:39:31 | |
| Plantae Liliopsida (monocots) | Arecales | Cocos nucifera | Coconut | 866 | Coc n 1 | vicilin-like protein | 53 kDa | Indian subjects with airway allergy, skin prick test (2+ erythema to 3+ erythema plus =>3mm wheal) and basophil cellular tests to coconut pollen; 10 of 10 were positive by IgE ELISA, reducing immunoblot and basophil histamine release, as well as upregulation of CD 63 by FACS in a BAT. | 26426307 | 2 | 2016-03-02 12:00:00 | 2019-07-31 23:41:29 | |
| Plantae Eudikotyledons | Gentianales | Coffea arabica | Arabian coffee | 723 | Cof a 1 | Class III chitinase | 32 kDa | 3 of 17 coffee industry workers with symptoms of rhinoconjunctivitis when exposed to raw coffee dust had IgE that reacted in ELISA with the recombinant Cof a 1 produced in E. coli. | 22722540 | 2 | 2011-04-08 12:00:00 | 2019-07-31 23:46:30 | |
| Plantae Eudikotyledons | Gentianales | Coffea arabica | Arabian coffee | 774 | Cof a 2 | Metallothionein type 2 | 9 kDa | Four of 18 coffee workers with conjunctivitis or rhinitis associated with work place tested positive in IgE binding to rCof a 2 produced in E. coli. | 25962169 | 2 | 2015-12-10 12:00:00 | 2019-07-31 23:48:12 | |
| Plantae Eudikotyledons | Gentianales | Coffea arabica | Arabian coffee | 775 | Cof a 3 | Metallothionein type 3 | 7 kDa | Four of 18 coffee workers with conjunctivitis or rhinitis associated with work place tested positive in IgE binding to rCof a 2 produced in E. coli. | 25962169 | 2 | 2015-12-10 12:00:00 | 2019-07-31 23:49:00 | |
| Fungi Basidiomycota | Agaricales | Coprinus comatus | Shaggy mane | 223 | Cop c 1 | Leucine zipper protein | 11 kDa | Among 67 individuals with a positive skin prick test to C.comatus, 23 (34%) showed serum IgE binding to rCop c 1 in ELISA. rCop c 1 induced positive skin test responses in all 5 C.comatus-sensitized patients tested. - rCop c 1 was recognized by 25% of 92 tested sera from basidiomycetes-sensitized subjects. | 10482839 | 2 | 2003-09-01 12:00:00 | 2019-07-31 23:51:21 | |
| Fungi Basidiomycota | Agaricales | Coprinus comatus | Shaggy mane | 224 | Cop c 2 | Thioredoxin | 12 kDa | no data found | 2 | 2003-09-01 12:00:00 | 2019-08-01 00:03:05 | ||
| Fungi Basidiomycota | Agaricales | Coprinus comatus | Shaggy mane | 225 | Cop c 3 | Putative RNA-binding protein | 37 kDa | No data found | 2 | 2003-09-01 12:00:00 | 2023-11-02 18:03:22 | ||
| Fungi Basidiomycota | Agaricales | Coprinus comatus | Shaggy mane | 226 | Cop c 5 | 16 kDa | No data found | 2 | 2003-09-01 12:00:00 | 2019-08-01 00:03:40 | |||
| Fungi Basidiomycota | Agaricales | Coprinus comatus | Shaggy mane | 227 | Cop c 7 | 16 kDa | no data found | 2 | 2003-09-01 12:00:00 | 2019-08-01 00:03:47 | |||
| Animalia Arthropoda | Blattodea | Coptotermes formosanus | Formosan subterranean termite | 916 | Copt f 7 | Tropomyosin | 35.4 kDa | Positive case histories of inhalation allergy and immunoCAP scores to cockroach, HDM and or shrimp, with 5 of 16 patients positive and 2 negative controls. 1 subject was tested with basophil activation and results were comparable to Pen a 1 response. Tests were with natural protein and E. coli produced recombinant protein. | 29508724 | 2 | 2018-01-03 01:00:21 | 2026-02-18 17:04:25 | |
| Plantae Eudikotyledons | Fagales | Corylus avellana | Hazelnut | 228 | Cor a 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 17 kDa | All 65 patients allergic to hazelnut tested showed IgE binding to Cor a 1 on immunoblot. - IgE binding to rCor a 1.0101: medline 93185652 | 11898007 | 2 | 2003-03-20 12:00:00 | 2019-08-01 22:09:44 | |
| Plantae Eudikotyledons | Fagales | Corylus avellana | Hazelnut | 234 | Cor a 2 | Profilin | 14 kDa | 15.4% of 65 hazelnut allergic patients had IgE biding to rCor a 2 on immunoblot. | 15233621 | 1 | 2003-03-27 12:00:00 | 2025-08-25 16:37:02 | |
| Plantae Eudikotyledons | Fagales | Corylus avellana | Hazelnut | 778 | Cor a 6 | Isoflavone reductase homologue | 35 kDa | 2 | 2013-07-17 12:00:00 | 2019-08-01 22:11:20 | |||
| Plantae Eudikotyledons | Fagales | Corylus avellana | Hazelnut | 235 | Cor a 8 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | Seven patients with severe anaphylactic reactions to hazelnut showed specific IgE binding to Cor a 8. | 11898007 | 1 | 2003-03-27 12:00:00 | 2025-04-10 18:14:47 | |
| Plantae Eudikotyledons | Fagales | Corylus avellana | Hazelnut | 236 | Cor a 9 | 11S seed storage globulin (legumin-like) | 40 kDa | By using 2-dimensional proteomics, a protein fraction at 40 kd was recognized by serum IgE in 86% (12/14) of the patients with hazelnut allergy with systemic reactions | 12209105 | 1 | 2003-03-27 12:00:00 | 2019-08-01 22:17:13 | |
| Plantae Eudikotyledons | Fagales | Corylus avellana | Hazelnut | 229 | Cor a 10 | Luminal binding protein | 70 kDa | 12811017 | 2 | 2003-03-27 12:00:00 | 2020-01-16 00:04:09 | ||
| Plantae Eudikotyledons | Fagales | Corylus avellana | Hazelnut | 230 | Cor a 11 | 7S seed storage globulin (vicilin-like) | 48 kDa | On immunoblot, rCor a 11.0101 and nCor a 11 bound IgE from 43% and 47%, respectively, of 65 sera from adult hazelnut allergic patients from central Europe. In ELISA, rCor a 11.0101 and nCor a 11 bound IgE from 40% and 47% of the sera. | 15233621 | 1 | 2003-03-27 12:00:00 | 2022-04-29 12:57:06 | |
| Plantae Eudikotyledons | Fagales | Corylus avellana | Hazelnut | 231 | Cor a 12 | 17 kDa oleosin | 17 kDa | IgE prevalence:63%. Method(s):RAST, CAP, Blot with a semi-purified natural oleosin fraction obtained from oilbodies purified from hazelnut. This fraction also contained a unidentified 27 kD protein and the hazelnut 11S globulin (around 20 kD). In addition blots were done with recombinant oleosin. Number of patients tested: 118/185 patients with hazelnut and/or peanut ingestion related symptoms. | 1 | 2008-07-11 12:00:00 | 2019-01-09 17:36:10 | ||
| Plantae Eudikotyledons | Fagales | Corylus avellana | Hazelnut | 232 | Cor a 13 | 14-16 kDa oleosin | 14-16 kDa | IgE prevalence:63%. Method(s):RAST, CAP, Blot with a semi-purified natural oleosin fraction obtained from oilbodies purified from hazelnut. This fraction also contained a unidentified 27 kD protein and the hazelnut 11S globulin (around 20 kD). In addition blots were done with recombinant oleosin. Number of patients tested: 118/185 patients with hazelnut and/or peanut ingestion related symptoms. | 1 | 2008-07-11 12:00:00 | 2019-01-09 17:36:44 | ||
| Plantae Eudikotyledons | Fagales | Corylus avellana | Hazelnut | 233 | Cor a 14 | 2S albumin | 10 kDa reducing | 5/15 hazelnut allergic individuals had IgE that reacted with the HPLC purified natural 2S albumin from hazelnut. The assignement of the identity of the protein was done by determining sequences of its peptide fragments by mass-spectrometry. | 20373288 | 1 | 2008-10-23 12:00:00 | 2019-01-09 17:37:58 | |
| Plantae Eudikotyledons | Fagales | Corylus avellana | Hazelnut | 968 | Cor a 15 | Oleosin | 17 kDa | Pediatric food allergic subjects, 17 tested positive for IgE binding out of 26 subjects to natural and recombinant protein. There were 5 negative controls. IgE binding was with 1D and 2D immunoblots from oilbody extracts. Also 2 ug of recombinant protein could inhibit IgE binding. Test subjects, 30 of 30 tested positive by SPT to hazelnut. 18 of 30 subjects were positive by in vivo challenge to whole seed. | 34146442 | 1 | 2019-07-07 23:42:02 | 2023-07-17 18:17:06 | |
| Plantae Eudikotyledons | Fagales | Corylus avellana | Hazelnut | 1103 | Cor a 16 | 7S globulin seed storage protein (vicilin) containing N-terminal alpha-hairpinin (vicilin_N) peptides | 6-8 kDa and 47.5 kDa | 106 children with suspected hazelnut allergy were tested. All had IgE to hazelnut extract as measured by ImmunoCAP. Of those, 56 (53%) had positive ImmunoCAP to a recombinant protein containing 5 of the 12 N-terminal peptides, while 73 (69%) had IgE to the recombinant mature vicilin (containing only the cupin domains). | 35851969 | 1 | 2022-05-04 15:20:33 | 2022-12-07 13:58:55 | |
| Animalia Arthropoda | Decapoda | Crangon crangon | North Sea shrimp | 237 | Cra c 1 | Tropomyosin | ~38 kDa | 3/8 (38%) shrimp allergic patients had IgE binding to Cra c 1 in immunoblotting. 21/31 (68%) shrimp allergic sera had positive ImmunoCap results to Cra c 1. | 21784530 | 1 | 2009-01-23 12:00:00 | 2019-08-02 23:09:47 | |
| Animalia Arthropoda | Decapoda | Crangon crangon | North Sea shrimp | 238 | Cra c 2 | Arginine kinase | ~45 kDa | 3/8 (38%) shrimp allergic patients had IgE binding to Cra c 2 in immunoblotting. 9/31 (29%) shrimp allergic sera had positive ImmunoCap results to Cra c 2. | 21784530 | 1 | 2009-01-23 12:00:00 | 2019-08-02 23:10:45 | |
| Animalia Arthropoda | Decapoda | Crangon crangon | North Sea shrimp | 239 | Cra c 4 | Sarcoplasmic calcium-binding protein | ~25 kDa | 3/8 (38%) shrimp allergic patients had IgE binding to Cra c 4 in immunoblotting. 11/31 (35%) shrimp allergic sera had positive ImmunoCap results to Cra c 4. | 21784530 | 1 | 2009-01-23 12:00:00 | 2019-08-02 23:11:50 | |
| Animalia Arthropoda | Decapoda | Crangon crangon | North Sea shrimp | 240 | Cra c 5 | Myosin, light chain 1 | ~17.5 kDa | 5/8 (63%) shrimp allergic patients had IgE binding to Cra c 5 in immunoblotting. 6/31 (19%) shrimp allergic sera had positive ImmunoCap results to Cra c 5. | 21784530 | 1 | 2009-01-23 12:00:00 | 2019-08-02 23:13:45 | |
| Animalia Arthropoda | Decapoda | Crangon crangon | North Sea shrimp | 241 | Cra c 6 | Troponin C | ~21 kDa | 4/8 (50%) shrimp allergic patients had IgE binding to Cra c 6 in immunoblotting. 9/31 (29%) shrimp allergic sera had positive ImmunoCap results to Cra c 6. | 21784530 | 1 | 2009-01-23 12:00:00 | 2019-08-02 23:15:47 | |
| Animalia Arthropoda | Decapoda | Crangon crangon | North Sea shrimp | 242 | Cra c 8 | Triosephosphate isomerase | ~28 kDa | 5/8 (63%) shrimp allergic patients had IgE binding to Cra c 8 in immunoblotting. 7/31 (23%) shrimp allergic sera had positive ImmunoCap results to Cra c 8. | 21784530 | 1 | 2009-01-23 12:00:00 | 2019-08-02 23:17:33 | |
| Animalia Mollusca | Ostreida | Crassostrea angulata [Magallana angulata] | Portuguese oyster | 1127 | Cra a 1 | Tropomyosin | 38 kDa | Thirty patients with reported symptoms after consumption of oyster and a positive crab ImmunoCAP (f23, Thermo Fisher) were tested. Of those, IgE from 10 sera (33%) reacted with recombinant Cra a 1 in a dot-blot. Twenty patients were also tested by a BAT assay with rCra a 1, 5 of which were positive. | 35848932 | 1 | 2023-07-24 15:07:41 | 2023-07-24 15:44:58 | |
| Animalia Mollusca | Ostreida | Crassostrea angulata [Magallana angulata] | Portuguese oyster | 1092 | Cra a 2 | Arginine kinase | 38 kDa to 41 kDa | 20 of 30 subjects with history of allergy to oyster were positive by ImmunoCAP, ELISA and Dot blot to natural and recombinant protein. Sequences are in public databases | 34664604 | 1 | 2022-03-22 15:46:40 | 2022-03-22 15:55:37 | |
| Animalia Mollusca | Ostreida | Crassostrea angulata [Magallana angulata] | Portuguese oyster | 1056 | Cra a 4 | Sarcoplasmic calcium binding protein | 20 kDa | 14 of 30 molluscan allergic consumers had IgE binding to natural and recombinant protein of this species by ELISA, ImmunoCAP and dot blot. The sequence is identical to the Portuges oyster protein | 32298098 | 1 | 2021-03-20 22:03:19 | 2021-03-20 22:03:41 | |
| Animalia Mollusca | Ostreida | Crassostrea gigas [Magallana gigas] | Pacific oyster | 902 | Cra g 1 | tropomyosin | 38 kDa | Serum donors reported allergic symptoms when eating molluscs or crustaceans, were tested by SPT with extract of source, serum IgE by western blot, 5 positive IgE binders out of 10 subjects, and 3 negative controls, using natural and recombinant protein made in E. coli. | 1 | 2017-09-20 14:37:03 | 2025-08-25 18:07:42 | ||
| Animalia Chordata | Crocodylia | Crocodylus porosus | Australian saltwater crocodile | 925 | Cro p 1 | beta-parvalbumin | 11.6 kDa | Patients with a clinical history to fish, and one with clinical history of allergy to consumption of crocodile meat. 37 with IgE binding out of 66 to natural protein in reducing immunoblot, 7 of 12 positive to by SPT to prick-to-prick heat treated crocodile tissue. | 35616897 | 1 | 2018-04-15 22:44:53 | 2022-05-31 17:41:41 | |
| Animalia Chordata | Crocodylia | Crocodylus porosus | Australian saltwater crocodile | 926 | Cro p 2 | alpha-parvalbumin | 13 kDa | All patients had a history of food allergy to consumption of fish. One also to consumption of crocodile. 27 of 66 had positive IgE binding to native protein by immunoblot. 7 of 12 were positive by prick-to-prick with heated crocodile meat. | 35616897 | 1 | 2018-04-15 22:58:12 | 2022-05-31 17:42:43 | |
| Plantae Liliopsida (monocots) | Asparagales | Crocus sativus | Saffron crocus | 243 | Cro s 1 | Ole e 1-like protein | 21 kDa | 26989701 | 2 | 2006-11-03 12:00:00 | 2020-05-13 21:49:55 | ||
| Plantae Liliopsida (monocots) | Asparagales | Crocus sativus | Saffron crocus | 244 | Cro s 2 | Profilin | 14 kDa | 2 | 2006-11-03 12:00:00 | 2019-08-03 00:39:07 | |||
| Plantae Pinopsida | Cupressales | Cryptomeria japonica | Sugi, Japanese cedar | 245 | Cry j 1 | Pectate lyase | 41-45 kDa (45-50 kDa non-red) | >90% of 145 sera from CJ pollinosis patients reacted with purified Cry j 1 in ELISA. Dose-dependent histamine release in 2 patients tested. - 12 out of 14 sera from patients with Japanese cedar pollinosis reacted with Cry j 1 in IgE ELISA: medline 90342988. - Purified allergen gives positive skin responses in intradermal skin test: medline 83109936. | 8564723 | 2 | 2003-03-27 12:00:00 | 2019-08-03 00:43:49 | |
| Plantae Pinopsida | Cupressales | Cryptomeria japonica | Sugi, Japanese cedar | 246 | Cry j 2 | Polygalacturonase | 45 kDa (37 kDa non-red) | >90% of 145 sera from CJ pollinosis patients reacted with purified Cry j 2 in ELISA. Dose-dependent histamine release in 2 patients tested - 10 of 14 sera of patients with Japanese cedar pollinosis reacted with Cry j 2 in IgE ELISA: medline 90342988. | 8564723 | 2 | 2003-04-01 12:00:00 | 2019-08-03 00:53:42 | |
| Plantae Pinopsida | Cupressales | Cryptomeria japonica | Sugi, Japanese cedar | 1140 | Cry j 3 | Thaumatin-like protein (pathogenesis-related protein PR-5) | 27 kDa | One hundred patients with allergy to Japanese cedar pollen, diagnosed based on typical symptoms and specific IgE (ImmunoCAP class >= 2), were tested. Of those, 27 sera contained IgE specific to highly purified natural Cry j 3. The allergen could activate basophils from a Cry j 3-sensitized patient in a histamine release assay. | 17441795 | 2 | 2023-12-14 14:13:23 | 2023-12-14 14:54:52 | |
| Plantae Pinopsida | Cupressales | Cryptomeria japonica | Sugi, Japanese cedar | 1009 | Cry j 7 | Gibberellin-regulated protein | 7 kDa | 16 of 16 subjects with Cupressaceae pollinosis and peach allergy were positive to natural purified protein by ImmunoCAP. Approved for publication in Clin Exp Allergy, doi: 10.1111/cea.13675 | 2 | 2020-03-24 19:20:49 | 2020-06-24 19:50:42 | ||
| Animalia Arthropoda | Siphonaptera | Ctenocephalides felis | Cat flea | 247 | Cte f 1 | FS-1 | 18 kDa | After 2 weeks of exposure to chambered fleas, all 30 experimentally sensitized dogs showed serum IgE binding to rCte f 1 in ELISA. Of 10 clinical flea-allergic dogs, 8 (80%) showed IgE binding to rCte f1 in ELISA. IgE binding to flea serum antigens could be inhibited by rCte f 1 > 80%. - All 6 sensitized dogs tested had positive intradermal skin test in response to recombinant Cte f 1. Frank,G.R. et al. Adv. Vet. Dermatol. 3, 201-212 (1998) | 11074254, 8334536 | 4 | 2003-06-17 12:00:00 | 2023-11-02 18:23:04 | |
| Animalia Arthropoda | Siphonaptera | Ctenocephalides felis | Cat flea | 248 | Cte f 2 | Venom antigen 5 | 27 kDa | no information found | 8334536 | 4 | 2003-06-17 12:00:00 | 2023-11-02 18:25:28 | |
| Animalia Arthropoda | Siphonaptera | Ctenocephalides felis | Cat flea | 249 | Cte f 3 | 25 kDa | Of 20 flea-allergic dog sera tested, at least 40% showed IgE binding to a protein with molecular weight of 25 kD on immunoblot | 8446466,8334536 | 4 | 2003-07-01 12:00:00 | 2019-08-09 06:48:16 | ||
| Animalia Chordata | Cypriniformes | Ctenopharyngodon idella | Grass carp | 951 | Cten i 1 | Beta-parvalbumin | 9 kDa | 46 subjects with histories of allergy following consumption of fish were tested by IgE binding to recombinant protein by ELISA. 43 were positive, and more so than to cod parvalbumin Gad c 1. | 32323392 | 1 | 2019-01-17 00:44:43 | 2022-05-10 18:31:55 | |
| Plantae Eudikotyledons | Cucurbitales | Cucumis melo | Muskmelon | 250 | Cuc m 1 | Alkaline serine protease (cucumisin) | 67 kDa | N.A | 12801320 | 1 | 2003-06-19 12:00:00 | 2019-08-09 06:54:04 | |
| Plantae Eudikotyledons | Cucurbitales | Cucumis melo | Muskmelon | 251 | Cuc m 2 | Profilin | 14 kDa | Sera from 21 Spanish patients with OAS induced by melon (history, PPT with fresh melon, sIgE using melon ImmunoCAP, DBPCFC) were tested. Fifteen sera (71%) contained IgE to nCuc m 2 as determined by immunoblot with melon extract, with the identity of the 13 kDa band confirmed by immunoblot with a rabbit anti-profilin antibody and inhibition with rBet v 2. For the characterization of recombinant Cuc m 2 isoallergens see the isoallergen records. | 12642849 | 1 | 2004-04-18 12:00:00 | 2026-01-27 16:26:42 | |
| Plantae Eudikotyledons | Cucurbitales | Cucumis melo | Muskmelon | 252 | Cuc m 3 | Pathogenesis-related protein PR-1 | 17 kDa | 12 of 17 individual sera from patients with melon allergy showed specific IgE to the purified Cuc m 3 on ELISA. | 15480331 | 1 | 2006-11-03 12:00:00 | 2019-08-09 06:58:12 | |
| Plantae Eudikotyledons | Cucurbitales | Cucurbita maxima | Pumpkin | 958 | Cuc ma 4 | 11S globulin | 50 kDa non reducing; 35 kDa and 23 kDa reducing | Two of two with case history of food allergy to ingestion of pumpkin seeds or gourd seeds, positive by IgE binding with ELISA and with immunoblots | 32706416 | 1 | 2019-05-17 23:12:43 | 2020-12-30 16:59:24 | |
| Plantae Eudikotyledons | Cucurbitales | Cucurbita maxima | Pumpkin | 959 | Cuc ma 5 | 2S albumin | 14 kDa | Case history of food allergy and positive IgE binding for 4 of 4 subjects reporting allergies to consumption of pumpkin seeds and with SPT+ responses. | 32706416 | 1 | 2019-05-18 00:14:17 | 2020-12-30 17:00:43 | |
| Animalia Arthropoda | Diptera | Culex quinquefasciatus | Southern house mosquito | 941 | Cul q 2 | Salivary odorant binding protein D7clu12 | 33 kDa | 15 of 15 subjects with immediate or delayed skin reactions to mosquito bite had positive IgE binding to immunoblots of native protein. One non-allergic subject was negative | 32099589 | 4 | 2018-10-10 00:28:14 | 2022-09-19 15:43:54 | |
| Animalia Arthropoda | Diptera | Culex quinquefasciatus | Southern house mosquito | 942 | Cul q 3 | Salivary odorant binding protein D7clu1 | 35 kDa | 11 of 15 subjects with immediate or delayed skin reactions to a mosquito bite were IgE binding positive in immunoblots to natural protein. One non-allergic negative control. | 32099589 | 4 | 2018-10-10 00:54:59 | 2022-09-19 15:44:45 | |
| Plantae Pinopsida | Cupressales | Cupressus arizonica | Cypress | 253 | Cup a 1 | Pectate lyase | 43 kDa | Serum samples from 7 selected Cypressus arizonica-allergic patients all showed IgE binding to rCup a 1 (expressed in rabbit reticulocytes) on immunoblot | 11122214 | 2 | 2003-04-02 12:00:00 | 2019-08-09 07:05:24 | |
| Plantae Pinopsida | Cupressales | Cupressus sempervirens | Common cypress | 254 | Cup s 1 | Pectate lyase | 43 kDa | 2 | 2003-04-02 12:00:00 | 2019-08-15 00:57:33 | |||
| Plantae Pinopsida | Cupressales | Cupressus sempervirens | Common cypress | 889 | Cup s 2 | Polygalacturonase | 43 kDa | sera from 19 of 31 subjects with airway allergy in areas exposed to Common cypress (Curessus sempervirens) were positive to a 43 kDa protein based on immunoblots. The protein was characterized and demonstrated to be highly identical to Jun a 2 (~95% identity) and to Cha o 2 (80%). | 28439939 | 2 | 2017-01-11 16:03:09 | 2019-08-09 07:16:52 | |
| Plantae Pinopsida | Cupressales | Cupressus sempervirens | Common cypress | 255 | Cup s 3 | Thaumatin-like protein | 34 kDa | 17042139 | 2 | 2004-04-25 12:00:00 | 2019-08-09 07:17:21 | ||
| Plantae Pinopsida | Cupressales | Cupressus sempervirens | Common cypress | 997 | Cup s 7 | Gibberellin-regulated protein, cypmaclein, BP14 | 9.5 kDa | Five patients with allergy to Cypress pollen had IgE binding to this protein presented in FABER test | 31376732 | 2 | 2019-12-18 04:07:13 | 2025-08-26 13:09:05 | |
| Fungi Ascomycota | Pleosporales | Curvularia lunata (Cochliobolus lunatus) | 256 | Cur l 1 | Serine protease | 31 kDa | 12 of 15 (80%) patients were IgE positive in immunoblotting and ELISA | 15005766 | 2 | 2009-09-25 12:00:00 | 2019-08-09 07:22:07 | ||
| Fungi Ascomycota | Pleosporales | Curvularia lunata (Cochliobolus lunatus) | 257 | Cur l 2 | Enolase | 48 kda | 16779678 | 2 | 2009-09-25 12:00:00 | 2019-08-09 07:22:57 | |||
| Fungi Ascomycota | Pleosporales | Curvularia lunata (Cochliobolus lunatus) | 258 | Cur l 3 | Cytochrome c | 12 kDa | In vivo testing of Cur l 3 in allergic patients showed marked positive skin reactivity in 60% fungal positive cases (n = 96). | 18186808 | 2 | 2009-09-25 12:00:00 | 2019-08-09 07:32:08 | ||
| Fungi Ascomycota | Pleosporales | Curvularia lunata (Cochliobolus lunatus) | 662 | Cur l 4 | Subtilisin like serine protease | 54 kDa | 13 of 16 patients' samples showed significant basophil histamine release upon stimulation with purified recombinant Cur l 4. | 20667621 | 2 | 2010-02-09 12:00:00 | 2020-05-14 17:50:41 | ||
| Plantae Liliopsida (monocots) | Poales | Cynodon dactylon | Bermuda grass | 259 | Cyn d 1 | Beta-expansin | 32 kDa | CD1 | Patients allergic to Bermuda grass pollen showed IgE binding to Cyn d 1 expressed in yeast on immunoblot - IgE binding to immunoblots of Cyn d 1 was found to occur in 9/24 patient sera. | 7687099 1955635 | 2 | 2003-02-06 12:00:00 | 2020-05-14 22:06:04 |
| Plantae Liliopsida (monocots) | Poales | Cynodon dactylon | Bermuda grass | 265 | Cyn d 7 | Polcalcin | 12 kDa | Affinity purified IgE of allergics using recombinant Cyn d 7 showed specific binding to a 12 kDa protein in a Western Blot of Bermuda grass pollen extract. | 9363908 | 2 | 2003-02-06 12:00:00 | 2020-05-14 22:07:16 | |
| Plantae Liliopsida (monocots) | Poales | Cynodon dactylon | Bermuda grass | 260 | Cyn d 12 | Profilin | 14.5 kDa | Cyn d 12 from Bermuda grass pollen gave rise to 20% positive reaction rate with IgE in sera from 30 patients with Bermuda grass pollen allergy. | 9420135 | 2 | 2003-02-06 12:00:00 | 2020-05-14 22:08:23 | |
| Plantae Liliopsida (monocots) | Poales | Cynodon dactylon | Bermuda grass | 261 | Cyn d 15 | 9 kDa | 2 | 2006-11-03 12:00:00 | 2019-08-09 07:42:31 | ||||
| Plantae Liliopsida (monocots) | Poales | Cynodon dactylon | Bermuda grass | 262 | Cyn d 22 | enolase | 2 | 2004-04-25 12:00:00 | 2019-08-09 07:44:07 | ||||
| Plantae Liliopsida (monocots) | Poales | Cynodon dactylon | Bermuda grass | 263 | Cyn d 23 | 9 kDa | 2 | 2003-03-06 12:00:00 | 2019-08-09 07:44:21 | ||||
| Plantae Liliopsida (monocots) | Poales | Cynodon dactylon | Bermuda grass | 264 | Cyn d 24 | Pathogenesis-related protein PR-1 | 21 kDa | Purified natural Cyn d 24 bound IgE from 23 out of 35 Bermuda grass pollen allergics sera. | 16336260 | 2 | 2006-11-03 12:00:00 | 2020-05-14 22:09:56 | |
| Animalia Chordata | Cypriniformes | Cyprinus carpio | Common carp | 781 | Cyp c 1 | beta-parvalbumin | 12 kDa | All four tested sera of fish-allergic patients contained IgE binding to purified natural Cyp c 1. In an IgE inhibition assay, IgE binding of 11 of 11 fish allergic patients' sera to extracts from cod, tuna and salmon was inhibited by nCyp c 1. | 10764710 | 1 | 2013-09-10 12:00:00 | 2019-08-09 07:49:05 | |
| Animalia Chordata | Cypriniformes | Cyprinus carpio | Common carp | 1045 | Cyp c 2 | beta enolase | 47 kDa | Five of 29 Fish allergic subjects had IgE binding to recombinant enolase by ELISA or dot blot. Two non-fish allergic subjects were negative. 24 of 29 patients were positive by SPT to commercial carp extract f233. The enolase is a minor allergen with parvalbumin being the major one for most subjects. | 1 | 2020-12-11 21:32:09 | 2020-12-11 21:32:25 | ||
| Plantae Liliopsida (monocots) | Poales | Dactylis glomerata | Orchard grass | 266 | Dac g 1 | Beta-expansin | 32 kDa | Ag Dg1 | Dac g 1 is recognized by serum IgE antibodies of 95% of human patients sensitive to D. glomerata pollen, as has been shown by the nitrocellulose immunoprint technique. | 2414230 | 2 | 2003-02-06 12:00:00 | 2019-08-09 07:51:09 |
| Plantae Liliopsida (monocots) | Poales | Dactylis glomerata | Orchard grass | 267 | Dac g 2 | 11 kDa | Recombinant Dac g 2 was recognized by human IgE antibodies in 33% (4/12) of sera randomly selected from grass-sensitive individuals and in 67% (14/21) of sera from patients receiving grass pollen immunotherapy | 1526648 | 2 | 2003-02-06 12:00:00 | 2019-08-09 07:52:44 | ||
| Plantae Liliopsida (monocots) | Poales | Dactylis glomerata | Orchard grass | 268 | Dac g 3 | 14 kDa | Dac g III | IgE binding to Dac g 3 in more than 60% of sera from Dac g pollen-allergic patients. IgE binding and induction histamin-release of rDac g 3 | 8811075 | 2 | 2003-02-06 12:00:00 | 2019-08-09 07:53:23 | |
| Plantae Liliopsida (monocots) | Poales | Dactylis glomerata | Orchard grass | 269 | Dac g 4 | 60 kDa | 23 out of 26 plasma samples, selected on basis of high IgG4 levels against Dactylis pollen extract, showed IgE binding to Dac g 4 on IEF-immunoprint | 8428167 | 2 | 2003-02-06 12:00:00 | 2019-08-09 07:53:37 | ||
| Plantae Liliopsida (monocots) | Poales | Dactylis glomerata | Orchard grass | 270 | Dac g 5 | 25/28 kDa | Dac g V | IgE binding to purified Dac g 5 in immunoblot, using a serum pool of grass sensitized patients. | 1611548 | 2 | 2003-02-11 12:00:00 | 2019-08-09 07:54:14 | |
| Plantae Eudikotyledons | Apiales | Daucus carota | Carrot | 271 | Dau c 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 16 kDa | All 6 carrot-allergic patients tested showed serum IgE binding to natural and recombinant Dau c 1 on immunoblot. | 10336602 | 1 | 2003-06-17 12:00:00 | 2019-08-09 07:56:08 | |
| Plantae Eudikotyledons | Apiales | Daucus carota | Carrot | 272 | Dau c 4 | Profilin | 14 kDa | 1 | 2003-06-17 12:00:00 | 2019-08-09 07:57:54 | |||
| Plantae Eudikotyledons | Apiales | Daucus carota | Carrot | 738 | Dau c 5 | Isoflavone reductase-like protein | 33 kDa | 1 | 2012-04-03 12:00:00 | 2019-08-15 00:36:58 | |||
| Animalia Cnidaria | Alcyonacea | Dendronephthya nipponica | Soft coral | 273 | Den n 1 | 53 kDa and 21 kDa band; (80 kDa non-red) | In 5 patients who suffered from red soft coral-induced asthma, purified Den n 1 induced strong immediate type intradermal reactions. | 11435730 | 2 | 2003-08-14 12:00:00 | 2019-08-15 00:56:17 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 274 | Der f 1 | Cysteine protease | 27 kDa | Of 13 mite-allergic patients tested, 10 had positive skin tests with 10(-4) ug/ml of Der f 1. In 63 sera from RAST-positive mite-allergic patients, 55 (87%) had IgE antibodies against Der f 1. | 2428875 | 2 | 2003-04-29 12:00:00 | 2019-08-15 00:59:24 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 283 | Der f 2 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 15 kDa | Of 51 sera from mite-allergic patients, 48 (94%) had IgE antibody to purified Der f 2, as measured by RIA. Positive skin reactions to Der f 2 were found in 11 out of 12 patients tested (LESSTHAN=10(-3) ug/ml) - Of 20 mite-allergic patients tested, 18 had IgE antibodies to purified Der f 2, as measured by RAST. Der f 2 induced basophil histamine release in all 16 patients tested: medline 87032478. | 3770975 | 2 | 2003-04-30 12:00:00 | 2023-11-09 13:24:40 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 285 | Der f 3 | Trypsin | 29 kDa | IgE antibodies to Der f 3 were detected by RIA in 8 out of 51 (16%) mite-allergic patients tested. | 8563488, 10779309 | 2 | 2003-04-30 12:00:00 | 2019-08-15 01:04:27 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 869 | Der f 4 | Alpha-amylase | 57.9 kDa | Eleven of 27 airway allergic subjects with IgE to Dermatophagoides farinae had positive IgE binding to recombinant alpha-amylase of D. farinae | 26842967 | 2 | 2016-04-02 12:00:00 | 2020-03-23 21:31:36 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 967 | Der f 5 | Group 5/21 allergen | 15.5 kDa | IgE binding in 58 of 192 airway allergic Chinese subjects using western blot, dot blot and ELISA with recombinant Der f 5. 20 control sera were negative. Previous publications reported IgE binding to a protein that is 100% identical in sequence between 1998 and 2015 and reviewed in 2007. Current work will be published soon | 18220991 | 2 | 2019-06-14 17:33:56 | 2023-11-09 14:21:12 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 286 | Der f 6 | Chymotrypsin | 25 kDa | DF5 | In sera from 88 mite-allergic patients, IgE antibodies to Der f 6 were detected in 36 (41%) sera by RAST. | 8334537 | 2 | 2003-05-06 12:00:00 | 2019-08-15 01:09:29 |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 287 | Der f 7 | Bactericidal permeability-increasing like protein | 30-31 kDa | Of 41 mite-allergic patients, 19 (46%) showed IgE binding to rDer f 7 in RIA. | 8556554 | 2 | 2003-05-06 12:00:00 | 2019-08-15 01:10:23 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 807 | Der f 8 | Glutathione S-transferase | 32 kDa | Asthmatic patients selected (41) by SPT to extract of D. farinae, then tested by ImmunoCAP, a pool of sera of DP + subjects had clear IgE binding on 2D gel electrophoresis. | 23481662 | 2 | 2014-10-28 12:00:00 | 2019-08-15 01:11:20 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 1165 | Der f 9 | Trypsin-like serine protease | 28 kDa | Thirty mite-allergic children with allergic asthma (symptoms + sIgE > 3 kU/L to Der f extract) were tested. Of those, 17 (57%) had IgE to rDer f 9.0101 as shown by ELISA. Sera from 5 non-alleric children were used as negative controls. | 27434417 | 2 | 2025-08-27 18:10:23 | 2025-08-27 18:10:23 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 275 | Der f 10 | Tropomyosin | 37 kDa | Mag 44 | 25 out of 31 (80.6%) mite-allergic patients (selected for high reactivity to D.farinae), showed IgE binding to purified Der f 10 in dot spot test. Of 13 patients tested, 6 had positive skin reactions to Der f 10. | 7622766 | 2 | 2003-04-29 12:00:00 | 2019-08-15 01:11:54 |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 276 | Der f 11 | Paramyosin | 98 kDa | In 2 panels of 73 mite skin-test-positive asthmatic children, 75-77.6% had positive serum IgE reactivity to rDer f 11 in immunodot assays. In a panel of 24 patients, 17 (70.8%) had positive skin tests to rDer f 11. - medline 98389068: 21 of 24 sera from patients with positive skin reaction to mites, showed IgE binding to purified Der f 11 in immunodot assay. | 9723675 | 2 | 2003-04-29 12:00:00 | 2019-08-15 01:12:25 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 277 | Der f 13 | Cytosolic fatty acid-binding protein | 15 kDa | 16585580 | 2 | 2007-02-08 12:00:00 | 2023-11-09 14:06:58 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 278 | Der f 14 | Apolipophorin | 177 kDa | mag 3 | Of 38 serum samples from mite-allergic patients, 32 (84.2%) showed IgE binding to Der f 14 purified from stored (fragmented) extract, and 25 (65.8%) to Der f 14 from fresh extract, as measured by ELISA. In 4 of 6 patients tested, Der f 14 induced basophil histamine release. | 10024227 | 2 | 2003-04-30 12:00:00 | 2019-08-15 01:14:01 |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 279 | Der f 15 | Chitinase, contains a C-terminal peritrophin-A-like domain | 98/109 kDa | Dogs!!! A purified preparation of 98/109kDa proteins elicited positive intradermal skin tests (IDST(s)) in almost all atopic dogs sensitized to D. farinae. Majority of sera showed IgE binding to 98/109 proteins in Western blots of D. farinae extracts. The allergen binds IgE in the sera of 70% of humans allergic to mites. | 11292526 | 4 | 2003-04-30 12:00:00 | 2023-11-09 14:27:44 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 280 | Der f 16 | Gelsolin/villin | 53 kDa | Recombinant Der f 16 bound IgE in 8 out of 17 (47%) sera from mite-allergic patients, as measured by enzyme immunoassay. | 11959139 | 2 | 2003-04-30 12:00:00 | 2019-08-15 01:22:33 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 281 | Der f 17 | Calcium binding protein | 53 kDa | As described in the publication, Der f 17 binds IgE in 35% of sera from mite-allergic patients. The authors described obtaining a cDNA clone, but did not provide a sequence. Tategaki A, Kawamoto S, Aki T, Jyo T, Suzuki O, Shigeta S, Ono K. Newly described house dust mite allergens. ACI International suppl. 1:74-76, 2000 | 2 | 2003-04-30 12:00:00 | 2019-08-15 01:26:42 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 282 | Der f 18 | Non-catalytic chitinase-like protein (contains a C-terminal peritrophin-A-like domain) | 60 kDa | ELISA showed that purified Der f 18 bound IgE in 54% of sera from patients with D farinae allergy. In addition, the 60-kd protein was able to bind IgE in 57% to 77% of D farinae-sensitized dogs. | 12847483 | 2 | 2003-05-06 12:00:00 | 2023-11-28 18:51:01 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 808 | Der f 20 | Arginine kinase | 40 kDa | Skin prick test with recombinant protein positive in 5 of 10 tested subjects, IgE binding by immunoblot in 4 of 4 selected SPT positive subjects, and 4 of 4 positive by ELISA | 2 | 2014-11-03 12:00:00 | 2019-08-15 01:28:59 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 791 | Der f 21 | Group 5/21 allergen | 14 kDa | 11 of 38 (28.9%) dust mite allergic children showed IgE binding to rDer f 21 on immunoblot. 42 of 98 (42.9%) dust mite allergic adults displayed positive response to rDer f 21 in skin prick test. | 27069539 | 2 | 2014-03-01 12:00:00 | 2023-11-09 14:22:21 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 284 | Der f 22 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 14.7 kDa | 30082894 | 2 | 2007-02-08 12:00:00 | 2023-11-09 13:25:33 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 934 | Der f 23 | Peritrophin-A-like protein | 19 kDa (Der f 23.01), 8 kDa (Der f 23.02) | Subjects clinical history was recorded with symptoms of rhinitis or bronchial asthma. Serum IgE reactions to Der f 23.0101 were measured including western blots, dot blots and ELISA, with 72 positive reactors out of 129 patients, and 31 negative controls for IgE binding. SPT was positive for 3 subjects out of 10 patients and 10 controls. E. coli produced recombinant protein was used in IgE binding and SPT tests. | 31173194,40321137 | 2 | 2018-05-04 22:59:52 | 2025-05-05 13:58:44 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 772 | Der f 24 | Ubiquinol-cytochrome c reductase binding protein; Cytochrome b-c1 complex subunit 7 | 13 kDa | Five of 10 subjects positive by SPT to Der p extract were also positive to recombinant Der p 24. Western blots of various parts of protein were done to test for IgE binding. | 31139345 | 2 | 2013-04-10 12:00:00 | 2022-04-12 12:22:49 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 809 | Der f 25 | Triosephosphate isomerase | 34 kDa | 31 of 41 HDM allergic patients showed IgE binding to Der f 25. Six of ten were positive by SPT to Der f 25. Basophils of two patients were activated by Der f 25. | 23481662 | 2 | 2014-11-03 12:00:00 | 2019-08-15 20:10:07 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 815 | Der f 26 | Myosin alkali light chain | 18 kDa | Five of 17 HDM allergic subjects were SPT+ to rDer f 26.0101; five of five by IgE immunoblot and five of five by ELISA. | 2 | 2014-11-05 12:00:00 | 2019-08-15 20:19:35 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 812 | Der f 27 | Serpin | 48 kDa | 8 of 19 (42.1%) subjects were positive by SPT to recombinant Der f 27. 3 of 3 DME allergic patients reacted to the Der f 27 by immunoblotting. | 26328010 | 2 | 2014-11-04 12:00:00 | 2019-08-15 22:53:26 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 813 | Der f 28 | Heat shock protein Hsp70 | 70 kDa | Serum IgE binding in 28 of 41 HDM allergic subjects, with SPT+ in 7 of 10 to rDer f 28. Also BAT positive in a few subjects. | 23481662 | 2 | 2014-11-04 12:00:00 | 2023-11-22 18:14:14 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 811 | Der f 29 | Peptidyl-prolyl cis-trans isomerase (cyclophilin) | 15 kDa | 35 of 41 HDM sensitized subjects had IgE binding to Der f 29, cyclophilin, by immunoblot, 9 shown in publication. The nine were positive by ELISA and activated CCR3 >20% in BAT. In addition, 7 or 10 HDM allergic subjects were SPT + to rDer f 29. | 23481662 | 2 | 2014-11-07 12:00:00 | 2019-08-15 20:27:50 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 814 | Der f 30 | Ferritin | 15 kDa | 26 of 41 HDM allergic subjects had IgE binding to rDer v 30.0101 and a pool of HDM allergic subjects IgE bound to ferritin in 2D immunoblot. 6 of 10 subjects were SPT+ to rDer f 30.0101. 6 of 6 had positive BAT to rDer f 30.0101 | 23481662 | 2 | 2014-11-05 12:00:00 | 2019-08-15 20:29:10 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 816 | Der f 31 | Cofilin | 15 kDa | 14 of 43 HDM allergic subjects were SPT+ to rDer f 31. Five of 5 were IgE + by Immunoblot, 5 of 5 were + by ELISA to rDer f 31. | 29102047 | 2 | 2014-11-05 12:00:00 | 2019-08-15 20:34:13 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 817 | Der f 32 | Inorganic pyrophosphatase | 35 kDa | Eight of 52 HDM allergic subjects were SPT+ to rDer f 32, 5 of 5 were + in immunoblots and 5 of 5 to ELISA with rDer f 32. | 31381937 | 2 | 2014-11-05 12:00:00 | 2022-10-18 14:55:11 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 818 | Der f 33 | alpha-tubulin | 52 kDa | Four of 16 HDM allergic sera are poaitive to Der f 33 by SPT, 3 o 3 by immunoblot and 3 of 3 for IgE western and immunoblot. | 2 | 2014-11-07 12:00:00 | 2019-08-15 20:39:08 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 880 | Der f 34 | Rid-like protein; enamine/imine deaminase | 16 kDa | Thirteen of 19 HDM allergic subjects had positive IgE binding to recombinant Der f 34 as measured by ELISA | 27539850 | 2 | 2016-09-13 12:00:00 | 2022-05-10 18:27:56 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 881 | Der f 35 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 14.4 kDa, natural and recombinant | 18 of 35 subjects with case history of inhalation allergy had in vitro IgE binding by in vitro tests using recombinant protein. | 28439905 | 2 | 2016-09-13 12:00:00 | 2023-11-09 13:26:53 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 893 | Der f 36 | C2 domain-containing protein | 23 kDa | Of 19 mite-sensitized individuals, 8 had serum IgE antibodies to recombinant Der f 36 (produced in E. coli or P. pastoris), as assessed by 1D immunoblot. Of 10 mite-sensitized individuals, 6 had serum IgE antibodies to natural Der f 36, as assessed by 2D immunoblot. | 28982170 | 2 | 2017-02-20 08:14:20 | 2023-06-23 15:10:54 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 960 | Der f 37 | Chitin binding protein (contains 2 peritrophin-A-like domains) | 29 kDa | IgE-ELISA positive ElISAs for 21.4% (41/192) of asthmatic subjects tested, and 4 of 10 were positive by IgE western blot and IgE-Dot blots | 2 | 2019-05-27 23:53:19 | 2023-11-09 14:14:14 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 1014 | Der f 38 | Bacteriolytic enzyme | 15 kDa | Eight of 30 subjects with airway allergy to HDM, were positive in SPT to the recombinant protein. 3 of 10 were positive by IgE dot blot and 3 of 6 were positive by basophil activation with CD 203c expression. | 34445142 | 2 | 2020-07-14 16:35:32 | 2021-10-05 20:57:31 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 957 | Der f 39 | Troponin C | 18 kDa | Subjects with rhinitis or asthma, 76 subjects tested for IgE binding by ELISA with 7 subjects having positive; western blot 7/7 were positive, dot blot, 6 of 7 were positive | Unpublished so far | 2 | 2019-05-01 04:12:18 | 2019-08-15 20:43:01 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 1085 | Der f 40 | Thioredoxin like protein | 12 kDa | Rhinitis or asthma and 12 subjects of 124 were positive by IgE ELISA and western blots 4 positive, dot blots 8 positive for IgE to this recombinant protein. there were 50 negative controls. | 37577028 | 2 | 2022-02-09 23:57:40 | 2024-10-04 17:30:37 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 1155 | Der f 42 | Na/K-exchanging ATPase beta-subunit | 36 kDa | Sera from 125 mite-allergic patients (symptoms, positive mite ImmunoCAP) were tested. Of those, 9 sera (7%) had IgE to recombinant Der f 42.0101 as determined by ELISA. All 9 positive sera also bound the recombinant allergen in a Western blot and a dot-blot assay. | 40510736 | 2 | 2024-09-03 16:44:48 | 2025-07-02 16:17:28 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 1156 | Der f 43 | Peroxiredoxin 1 | 27 kDa | Sera from 143 mite-allergic patients (symptoms, positive mite ImmunoCAP) were tested. Of those, 12 sera (8%) had IgE to recombinant Der f 43.0101 as dtermined by ELISA. All 8 positive sera also bound the recombinant allergen in a dot-blot assay. | 40510736 | 2 | 2024-09-03 17:10:15 | 2025-07-02 16:18:00 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides farinae | American house dust mite | 1157 | Der f 44 | Peroxiredoxin 2 | 25 kDa | Sera from 90 mite-allergic patients (symptoms, positive mite ImmunoCAP) were tested. Of those, 6 sera (7%) had IgE to recombinant Der f 44.0101 as determined by ELISA. All 6 positive sera also bound the recombinant allergen in a Western blot and a dot-blot assay. | 40510736 | 2 | 2024-09-03 17:25:15 | 2025-07-02 16:18:33 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides microceras | House dust mite | 288 | Der m 1 | Cysteine protease | 25 kDa | Of 111 homes from asthmatic childeren in Sweden, 37 (33%) contained measurable Der m 1 levels. In 34 of these 111 children IgE antibodies against D. microceras were detected. Association between Der m 1 exposure and IgE against D. microceras. | 9700039 | 2 | 2003-05-08 12:00:00 | 2019-08-15 20:43:58 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides microceras | House dust mite | 1082 | Der m 2 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 17 kDa | Subjects with airway allergy were tested and found to have IgE binding to extracted natural protein in Dermatophagoides microceras, and by western blot 12 of 18 allergic subjects had IgE binding to the 17 kDa protein | 2 | 2021-12-07 00:46:10 | 2025-10-21 13:20:45 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 289 | Der p 1 | Cysteine protease | 24 kDa | antigen P1 | In serum there is a high pos. correlation between IgE to Der p 1 and IgE to Dp, as measured by RIA and RAST (r=0.82, pLESSTHAN0.001, n=30). >75% of IgE to Dp is directed against Der p 1. - Of 11 mite-allergic patients tested, all had pos. skin test in response to Der p 1 (10(-2) ug/ml): medline 87009956 - Of 35 mite-allergic patients, 92% positive in Der p 1 RAST: medline 97030607 | 6771329 | 2 | 2003-05-06 12:00:00 | 2019-08-15 20:45:19 |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 293 | Der p 2 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 15 kDa | DPX | Of 12 mite-allergic patients tested, 9 had positive skin tests in response to Der p 2 at conc. LESSTHAN 10(-3) ug/ml. Of 65 mite-allergic patients, 59 showed IgE binding to Der p 2 in RAST - Of 45 Dp-sensitive patients tested, 32 (71%) positive in Der p 2 RAST: medline 88228791. - Of 35 mite-allergic patients, 100% positive in Der p 2 RAST: medline 97030607 | 2732406 | 2 | 2003-05-08 12:00:00 | 2023-11-09 13:28:48 |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 297 | Der p 3 | Trypsin | 31 kDa | All 55 Dp-sensitive patients tested showed IgE binding in RAST of purified Der p 3. - Of 35 mite-allergic patients tested, 97% was positive in Der p 3 RAST: medline 97030607 | 1537598 | 2 | 2003-05-08 12:00:00 | 2019-08-15 21:15:44 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 298 | Der p 4 | Alpha-amylase | 60 kDa | In immunoblots of purified Der p 4, 46% of 27 mite-allergic adults and 25% of 20 mite-allergic children showed IgE binding. - medline 20014678: Of 10 Dp-sensitive patients tested, 3 showed IgE binding to rDer p 4 in dot blot assay. | 1710630 | 2 | 2003-05-08 12:00:00 | 2020-03-23 21:32:00 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 299 | Der p 5 | Group 5/21 allergen | 14 kDa | Of 19 mite-allergic patients, 6 had serum IgE antibodies to rDer p 5, as measured by RIA. 7 (37%) patients had positive skin prick tests in response to rDer p 5 at 10(-4)to 10(-2) ug/ml. On immunoblots, 21 of 38 sera from mite-allergic subjects recognized rDer p 5 (medline 90010801) | 7798547,12580807 | 2 | 2003-05-06 12:00:00 | 2023-11-09 14:22:45 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 300 | Der p 6 | Chymotrypsin | 25 kDa | DP5 | IgE antibodies to Der p 6 were detected in 36 of 88 (41%)sera from mite-allergic patients by RAST. Of 18 patients tested, 8 patients (44%) had a positive intradermal skin test to Der p 6. - Of 35 mite-allergic patients tested, 65% was positive in Der p 6 RAST: medline 97030607 | 8334537 | 2 | 2003-05-08 12:00:00 | 2019-08-15 22:10:13 |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 301 | Der p 7 | Bactericidal permeability-increasing like protein | 26, 30 and 31 kDa | Of 30 mite-allergic children tested, 16 (53%) gave positive ractions in subcutaneous skin test with rDer p 7 (1ug/ml). 14 of 38 (37%) children showed serum IgE binding to rDer p 7 - Of 41 mite-allergic patients tested, 19 (46%) showed IgE binding to rDer p 7 in RIA; medline 96120794 | 10779281 | 2 | 2003-05-08 12:00:00 | 2019-08-15 22:10:36 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 302 | Der p 8 | Glutathione S-transferase | 27 kDa | 40% of mite-allergic sera recognized rDer p 8 on immunoblot. | 7918651 | 2 | 2003-05-08 12:00:00 | 2019-08-15 22:10:52 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 303 | Der p 9 | Collagenolytic serine protease | 29 kDa | Of 35 mite-allergic patients, 92% showed IgE binding to purified Der p 9 in RAST. | 8876548 | 2 | 2003-05-08 12:00:00 | 2019-08-15 22:11:13 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 290 | Der p 10 | Tropomyosin | 36 kDa | Of mite allergic patients, 5.6% shows IgE binding to rDer p 10. | 9545522 | 2 | 2003-05-08 12:00:00 | 2019-08-15 22:11:33 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 291 | Der p 11 | Paramyosin | 103 kDa | The prevalence of serum IgE reactivity to rDer p 11 on immunodot assay ranged from 41.7% to 66.7% in different allergic patient groups, whereas it was rare in non-atopic patients with urticaria (18.8%) and in normal individuals (8%). A high frequency (five out of eight) of MAST(Dp)- allergic serum samples had specific IgE-binding activity to rDer p 11 or its fragments on immunoblot assay, even though their IgE-binding activity to Dp extract was either weak or negative. | 15005727 | 2 | 2006-11-05 12:00:00 | 2019-08-15 22:11:56 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 868 | Der p 13 | Cytosolic Fatty Acid Binding Protein | 15 kDa | 224 "HDM-allergic" subjects living in Thailand, with rhinitis or asthma were tested for IgE binding to Dermatophagoides pteronyssinus ImmunoCAP and were class 3 or higher. Serum IgE binding to recombinant Der p 13 produced in Picchia, were tested by ELISA with 15 of 224 positive. | 2 | 2016-03-15 12:00:00 | 2019-08-15 22:16:40 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 292 | Der p 14 | Apolipophorin | 177 kDa | Der p 14 can induce high IgE responses and T cell stimulation. | 11306926 | 2 | 2003-05-08 12:00:00 | 2019-08-15 22:17:07 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 770 | Der p 15 | Chitinase, contains a C-terminal peritrophin-A-like domain | 58.8 and 61.4 kDa | Der p 15.0101 and Der p 15.0102 bound IgE in 19 out of 27 HDM allergic subjects (70%) by Pharmacia CAP assay. | 16776685 | 2 | 2014-11-19 12:00:00 | 2023-11-09 14:46:14 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 1131 | Der p 16 | Gelsolin | 55 kDa | Of 27 sera from asthmatic patients with positive ImmunoCAP to Der p, 14 (52%) had IgE to recombinant Der p 16.0101 produced in E. coli as measured by ELISA. In an IgE immunoblot with rDer p 16.0101, 8 of 12 (67%) sera bound to the allergen. | 2 | 2023-11-03 15:26:31 | 2023-11-06 15:02:40 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 771 | Der p 18 | Non-catalytic chitinase-like protein (contains a C-terminal peritrophin-A-like domain) | 49.2 kDa | Der p 18 bound IgE in 17 out of 27 (63%) of the HDM allergic sera by Pharmacia CAP assay | 16776685 | 2 | 2014-11-19 12:00:00 | 2023-11-28 18:51:47 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 294 | Der p 20 | Arginine kinase | 40 kDa | Recombinant Der f 20 was recognized by 6.6% of 129 Korean HDM allergic patients’ sera tested. | 16890759, 25749773 | 2 | 2006-02-25 12:00:00 | 2019-08-15 22:43:11 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 295 | Der p 21 | Group 5/21 allergen | 14.726 kDa | No information found. | 18445190 | 2 | 2006-02-25 12:00:00 | 2023-11-09 14:23:00 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 1164 | Der p 22 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 15 kDa | Of 149 sera from mite-allergic patients (reported symptoms + positive SPT to Der p extract), 80 (54%) had IgE to rDer p 22.0101 produced in E. coli, as determined by immuno-dot-blot. Signals were quatified using a human IgE standard, and 0.35 kU/L were used as a threshold for positive signals. Control sera from 27 non-allergic donors were negative. | 41036298 | 2 | 2025-08-26 17:18:19 | 2025-10-02 16:46:02 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 296 | Der p 23 | Peritrophin-like protein domain (PF01607) | 14 kDa (dimer) | IgE binding with 74% of 347 D. pteronyssinus allergic patients, levels of IgE comparable to Der p 1 and 2. Upregulated CD203c expression on basophils from D. pteronyssinus allergic patients. Protein in feces | 23460742 | 2 | 2008-07-04 12:00:00 | 2022-11-03 16:52:34 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 855 | Der p 24 | Ubiquinol-cytochrome c reductase binding protein; Cytochrome b-c1 complex subunit 7 | 13 kDa | IgE western blot analysis showed that the rDer p 24 reacted with serum IgEs from 8 individual HDM allergic patients. In SPTs with the Der p 24, 5/10 allergic patients (50%) had positive reactions | 31139345 | 2 | 2015-12-07 12:00:00 | 2022-04-12 12:22:13 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 950 | Der p 25 | Triosphosphate isomerase | 27 kDa | 12 of 26 allergic subjects were positive by SPT to recombinant protein. 14 of 26 by ELISA with recombinant protein. Subjects have airway allergy. | 2 | 2019-01-02 18:59:43 | 2019-08-15 23:02:36 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 969 | Der p 26 | Myosin light chain | 14.1 kDa | 16 of 26 subjects with perennial respiratory allergy, diagnosed with HDM allergy were positive in ELISA to recombinant Der p 26. Five of 20 were positive in SPT to recombinant Der p 26. Four controls were negative in both tests. | 29305317 | 2 | 2019-07-12 20:51:32 | 2025-08-25 18:13:04 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 1132 | Der p 27 | Serpin serine protease inhibitor | 45 kDa | Of 27 sera from asthmatic patients with positive ImmunoCAP to Der p, 6 (22%) had IgE to recombinant Der p 27.0101 produced in E. coli as measured by ELISA. In an IgE immunoblot with rDer p 27.0101, 11 of 14 (79%) sera bound to the allergen. | 2 | 2023-11-03 15:35:44 | 2023-11-06 15:03:43 | ||
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 970 | Der p 28 | Heat shock protein Hsp70 | 45 kDa | 18 of 26 subjects with perennial respiratory allergy, diagnosed with HDM allergy were positive in ELISA to recombinant Der p 28. Fourteen of 20 were positive in SPT to recombinant Der p 28. Four controls were negative in both tests | 29305317 | 2 | 2019-07-12 21:12:03 | 2023-11-22 18:13:46 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 971 | Der p 29 | Cyclophilin, peptidyl-prolyl cis-trans isomerase | 27.7 kDa | 10 of 26 subjects with perennial respiratory allergy, diagnosed with HDM allergy were positive in ELISA to recombinant Der p 29. Seven of 20 were positive in SPT to recombinant Der p 29. Four controls were negative in both tests | 29305317 | 2 | 2019-07-12 21:25:03 | 2025-08-25 18:41:58 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 972 | Der p 30 | Ferritin | 12.1 kDa | 12 of 26 subjects with perennial respiratory allergy, diagnosed with HDM allergy were positive in ELISA to recombinant Der p 30. Seven of 20 were positive in SPT to recombinant Der p 30. Four controls were negative in both tests | 29305317 | 2 | 2019-07-12 21:35:08 | 2019-08-15 23:07:16 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 973 | Der p 31 | Cofilin | 16.8 kDa | 9 of 26 subjects with perennial respiratory allergy, diagnosed with HDM allergy were positive in ELISA to recombinant Der p 31. Seven of 20 were positive in SPT to recombinant Der p 31. Four controls were negative in both tests | 29305317 | 2 | 2019-07-12 21:50:26 | 2019-08-15 23:08:06 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 974 | Der p 32 | Inorganic pyrophosphatase | 45 kDa | 12 of 26 subjects with perennial respiratory allergy, diagnosed with HDM allergy were positive in ELISA to recombinant Der p 32. Three of 20 were positive in SPT to recombinant Der p 32. Four controls were negative in both tests | 29305317 | 2 | 2019-07-13 01:12:16 | 2022-10-18 14:55:45 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 975 | Der p 33 | alpha-tubulin | 44.2 kDa | 17 of 26 subjects with perennial respiratory allergy, diagnosed with HDM allergy were positive in ELISA to recombinant Der p 33. Six of 20 were positive in SPT to recombinant Der p 33. Four controls were negative in both tests | 29305317 | 2 | 2019-07-13 01:18:14 | 2019-08-15 23:08:48 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 894 | Der p 36 | C2 domain containing protein | 23 kDa | Of 19 mite-sensitized individuals, 8 had serum IgE antibodies to recombinant Der p 36 (produced in E. coli or P. pastoris), as assessed by 1D immunoblot. Of 10 mite-sensitized individuals, 6 had serum IgE antibodies to nDer p 36, as assessed by 2D immunoblot. | 28982170 | 2 | 2017-02-20 08:24:37 | 2023-06-23 14:48:31 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 918 | Der p 37 | Chitin binding protein (contains 2 peritrophin-A-like domains) | 30 kDa | 40 of 207 inhalation allergic subjects had IgE binding to this recombinant protein by dotblot and by experimental ImmunoCAP, while 10 negative controls did not. Two of 7 subjects had positive basophil activation with recombinant protein using humanized RBL. | 34419535 | 2 | 2018-02-04 03:44:41 | 2024-09-17 13:25:39 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 949 | Der p 38 | Bacteriolytic enzyme | 15 kDa | 31 of 40 patients had IgE binding to recombinant protein, 18 of 40 were SPT + to the recombinant protein. BAT was positive in 3 of 3 sujects as measured by CD 203c expression | 34445142 | 2 | 2019-01-01 01:51:22 | 2021-10-05 21:00:24 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 1070 | Der p 39 | Troponin C | 18 kDa | 87 subjects with reported allergy to House Dust mites, were tested and 5 of the subjects had IgE binding to the cloned Troponin C of D. pteronyssinus based on western blot, dot blot and ELISA. 30 non-allergic subjects were negative. | 35600837 | 2 | 2021-08-03 19:23:01 | 2024-10-04 17:25:29 | |
| Animalia Arthropoda | Sarcoptiformes | Dermatophagoides pteronyssinus | European house dust mite | 1086 | Der p 40 | Thioredoxin like protein | 12 kDa | Serum donors diagnosed with asthma or rhinitis and with 9 of 112 having specific IgE to recombinant protein by ELISA, 3 of 9 by western blot, and 7 of 9 by dot blot. There were 50 negative controls. | 2 | 2022-02-10 00:10:16 | 2022-02-10 00:10:43 | ||
| Animalia Arthropoda | Hymenoptera | Dolichovespula arenaria | Yellow hornet | 304 | Dol a 5 | Antigen 5 | 23 kDa | All 15 vespid-allergic patients tested were skin test positive to purified yellow hornet Ag 5. >20% basophil histamine release was induced in 81% of the patients tested. J Gadde, DBK Golden, A Kagey-Sobotka, MD Valentine, LM Lichtenstein, TP King. 1986. J Allergy Clin Immunol 77, 143. Abstract. | 4 | 2003-05-31 12:00:00 | 2019-08-15 23:12:15 | ||
| Animalia Arthropoda | Hymenoptera | Dolichovespula maculata | White face hornet | 305 | Dol m 1 | Phospholipase A1B | 34 kDa | Of 12 vespid-allergic patients, 8 (66%) were skin test positive to white hornet PLA. >20% basophil histamine release was induced in 63% of the patients tested. J Gadde, DBK Golden, A Kagey-Sobotka, MD Valentine, LM Lichtenstein, TP King. 1986. J Allergy Clin Immunol 77, 143. Abstract. - Of 17 D. maculata-allergic patients, 13 showed IgE binding to purified Dol m 1 (identified by phospholipase activity) in RAST | 3989146 | 4 | 2003-05-31 12:00:00 | 2019-08-15 23:16:46 | |
| Animalia Arthropoda | Hymenoptera | Dolichovespula maculata | White face hornet | 306 | Dol m 2 | Hyaluronidase | 42 kDa | Of 11 vespid-allergic patients tested, 7 were skin test positive to purified white hornet hyaluronidase. >20% basophil histamine release was induced in 81% of patients tested. J Gadde, DBK Golden, A Kagey-Sobotka, MD Valentine, LM Lichtenstein, TP King. 1986. J Allergy Clin Immunol 77, 143. Abstract. - Of 17 D. maculata-allergic patients, 13 showed IgE binding to purified Dol m 2 (identified by hyaluronidase activity) in RAST. | 3989146 | 4 | 2003-05-31 12:00:00 | 2019-08-15 23:19:09 | |
| Animalia Arthropoda | Hymenoptera | Dolichovespula maculata | White face hornet | 307 | Dol m 5 | Antigen 5 | 23 kDa | - All 15 vespid-allergic patients were skin test positive with purified Ag 5 from white hornet venom. >20% basophil histamine release was induced in 81% of patients tested. J Gadde, DBK Golden, A Kagey-Sobotka, MD Valentine, LM Lichtenstein, TP King. 1986. J Allergy Clin Immunol 77, 143. Abstract. - Of 17 D. maculata-allergic patients, 11 showed IgE binding to Ag 5 in RAST. | 3989146 | 4 | 2003-05-31 12:00:00 | 2019-08-15 23:19:59 | |
| Fungi Ascomycota | Pleosporales | Epicoccum purpurascens | Soil fungus | 308 | Epi p 1 | Serine protease | 30 kDa | 14976389 | 2 | 2009-09-25 12:00:00 | 2020-05-14 17:51:30 | ||
| Animalia Chordata | Perissodactyla | Equus asinus | Donkey | 910 | Equ a 6 | Lysozyme | 15 kDa | IgE positive responses to purified lysozyme of horse (Equus caballus) and donkey (Equus asinus), 1 patient with dermal (urticaria) reactions to creams containing donkey milk, the second with dermatis following exposure to donkey milk in cosmetics and angioedema after ingesting a few drops of donkey milk. The horse and donkey lysozymes are 99% identical. The two patients had ~ IgE to pure donkey and horse lysozyme, a bit more reactivity in BAT to donkey. Seems both dermal and food allergens. | 30004599 | 3 | 2017-12-14 21:01:59 | 2020-05-14 23:38:58 | |
| Animalia Chordata | Perissodactyla | Equus caballus | Domestic horse | 309 | Equ c 1 | Lipocalin | 25 kDa | ALL1 horse | Sixteen patients with established allergy to natural Equ c 1 were selected and tested in immunoblot with rEqu c 1, all were positive. | 8955138 | 2 | 2003-02-05 12:00:00 | 2020-05-14 23:39:44 |
| Animalia Chordata | Perissodactyla | Equus caballus | Domestic horse | 310 | Equ c 2 | Lipocalin | 17 kDa | AL21 horse | IgE binding in immunoblot (11 of 23 patients tested); 33.3% of 21 horse sensitized patients tested showed IgE binding to Equ c 2. See also medline 98237590 March 2020, 20 or 22 of 35 subjects allergic to horse dander were positive in IgE binding to recombinant and natural protein preparations using ImmunoCAP | 9686871 | 2 | 2003-02-05 12:00:00 | 2020-03-26 19:47:36 |
| Animalia Chordata | Perissodactyla | Equus caballus | Domestic horse | 311 | Equ c 3 | Serum albumin | 67 kDa | Ag3 | IgE binding to 67 kD protein on immunoblot in 50% of patients tested | 8238811 | 2 | 2003-02-05 12:00:00 | 2019-08-15 23:31:16 |
| Animalia Chordata | Perissodactyla | Equus caballus | Domestic horse | 312 | Equ c 4 | Latherin | 17 kDa, 20.5 kDa | Equ c 5, ALL4 horse, ALL5 horse | 17 of 22 (77%) horse allergic patients showed IgE binding in ELISA; 9/9 sera showed IgE binding on immunoblot | 11358533 19478940 | 2 | 2003-02-05 12:00:00 | 2020-05-14 23:41:40 |
| Animalia Chordata | Perissodactyla | Equus caballus | Domestic horse | 313 | Equ c 5 | deleted (identical to Equ c 4); designation not available for future submissions | 2 | 2003-02-05 12:00:00 | 2019-08-15 23:34:15 | ||||
| Animalia Chordata | Perissodactyla | Equus caballus | Domestic horse | 909 | Equ c 6 | Lysozyme | 15 kDa | IgE positive responses to purified lysozyme of horse (Equus caballus) and donkey (Equus asinus), 1 patient with dermal (urticaria) reactions to creams containing donkey milk, the second with dermatis following exposure to donkey milk in cosmetics and angioedema after ingesting a few drops of donkey milk. The horse and donkey lysozymes are 99% identical. The two patients had ~ IgE to pure donkey and horse lysozyme, a bit more reactivity in BAT to donkey. Seems both dermal and food allergens. | 30004599 | 3 | 2017-12-14 20:45:15 | 2020-05-14 23:42:36 | |
| Animalia Arthropoda | Decapoda | Eriocheir sinensis | Chinese mitten crab | 841 | Eri s 2 | ovary development-related protein | 28.2 kDa | 6 out of 14 patients had positive IgE binding using natural protein through Immunoblot and 19 of 29 were positive by IgE ELISA to recombinant Eri s 2.0101. 9 out of 10 patients had positive IgE binding using recombinant protein through dot blot. | 27240706 | 1 | 2015-08-17 12:00:00 | 2019-08-15 23:35:36 | |
| Animalia Arthropoda | Euphausiacea | Euphausia superba | Antarctic krill | 1184 | Eup s 1 | Tropomyosin | 35 kDa | Sera from 18 shrimp-allergic patients were tested (symptoms + positive ImmunoCAP). Of those, 6 sera (33%) had IgE to a band corresponding to tropomyosin in a Western blot of krill extract. Five of the positive sera were tested with purified nEup s 1 on Western blot, all of which yielded a positive signal. Al 6 krill-positive patients reported allergic reactions after consuming krill, the other patients have not consumed krill. | 1 | 2025-10-03 15:21:38 | 2025-10-03 15:24:47 | ||
| Animalia Arthropoda | Sarcoptiformes | Euroglyphus maynei | Mayne's house dust mite | 314 | Eur m 1 | Cysteine protease | No information found. | 2 | 2003-05-13 12:00:00 | 2019-08-15 23:36:51 | |||
| Animalia Arthropoda | Sarcoptiformes | Euroglyphus maynei | Mayne's house dust mite | 316 | Eur m 2 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 14 kDa | IgE binding in allergen microarray. | 11790727, 11398074 | 2 | 2003-05-13 12:00:00 | 2023-11-09 13:29:23 | |
| Animalia Arthropoda | Sarcoptiformes | Euroglyphus maynei | Mayne's house dust mite | 317 | Eur m 3 | Trypsin | No information found. | 2 | 2003-05-13 12:00:00 | 2019-08-16 07:21:37 | |||
| Animalia Arthropoda | Sarcoptiformes | Euroglyphus maynei | Mayne's house dust mite | 318 | Eur m 4 | Alpha-amylase | 57 to 60 kDa | None of the 10 mite-allergic patients tested showed IgE-binding to rEur m 4 on dot blot. | 10545763 | 2 | 2003-05-08 12:00:00 | 2019-08-16 07:38:06 | |
| Animalia Arthropoda | Sarcoptiformes | Euroglyphus maynei | Mayne's house dust mite | 315 | Eur m 14 | Apolipophorin | 177 kDa | 10592463 | 2 | 2003-05-13 12:00:00 | 2020-05-14 17:36:03 | ||
| Animalia Arthropoda | Decapoda | Exopalaemon modestus | White legged freshwater shrimp | 945 | Exo m 1 | Tropomyosin | 38 kDa | 18 of 18 subjects allergic to freshwater shrimp, Exopalaemon modestus, as a food allergen were positive by Western blot with IgE binding and by ELISA. 10 Control, non-allergic subjects were negative. The native protein was isolated and shown to bind IgE. Publication manuscript has been submitted to Allergy. | 29287471; 31707198 | 1 | 2018-10-30 01:53:29 | 2020-01-22 23:57:08 | |
| Plantae Eudikotyledons | Caryophyllales | Fagopyrum esculentum | Common buckwheat | 683 | Fag e 2 | 2S albumin | 16 kDa | BWp16 | 13/17 buckwheat allergic patients had IgE that reacted with the purified natural Fag e 2 (Publication: PubMed number 16549935). 13/15 buckwheat allergic patients had IgE that reacted with the purified natural Fag e 2 (Publication: PubMed number 18520034). 24/29 buckwheat allergic patients had IgE that reacted with the purified recombinant Fag e 2.0101 (Publication: PubMed number 18520034). | 16549935, 18520034 | 1 | 2010-05-27 12:00:00 | 2019-08-16 22:27:56 |
| Plantae Eudikotyledons | Caryophyllales | Fagopyrum esculentum | Common buckwheat | 739 | Fag e 3 | alpha-hairpinin | 19 kDa (fragment) | About 83.3% of 18 buckwheat allergic patients had CAP sIgE bound to rFag e 3 measured by ELISA. | 17641547 | 1 | 2012-04-05 12:00:00 | 2023-03-15 17:38:54 | |
| Plantae Eudikotyledons | Caryophyllales | Fagopyrum esculentum | Common buckwheat | 900 | Fag e 4 | Hevein-like antimicrobial peptide, Fa-AMP | 3.9 kDa | Seven serum donors with convincing case histories of buckwheat allergy were tested. Food challenges were performed with positive outcome in 3/7 patients whereas not done in 4/7. SPTs were performed using total extract of the source as well as for oral food challenges. Serum derived IgE to native proteins from the extract was tested by western blot (6/7 positive). 5/7 samples were positive to purified Fag e 4 in ELISA. Natural exposure is by ingestion. Controls were performed with sera from 5 healthy donors, and 28 sera from atopic controls. | 29171912 | 1 | 2017-04-21 13:33:36 | 2025-08-25 18:45:58 | |
| Plantae Eudikotyledons | Caryophyllales | Fagopyrum esculentum | Common buckwheat | 903 | Fag e 5 | Vicilin-like seed storage protein, 8S globulin | 55 kDa | Seven subjects positive by case history, two of the seven positive by food challenge. In vitro IgE testing by ELISA: six of seven positive. Controls were performed with sera from 5 healthy donors, and 28 sera from atopic controls. Testing was to native protein (identified by LC-MS/MS) purified from buckwheat seed. | 29171912 | 1 | 2017-10-07 10:14:14 | 2025-08-25 18:48:12 | |
| Plantae Eudikotyledons | Caryophyllales | Fagopyrum tataricum | Tartarian buckwheat | 724 | Fag t 2 | 2S albumin | 16 kDa | 3 of 8 tartarian buckwheat allergic individuals had IgE that reacted in ELISA with the purifed Fag t 2. 3 of 8 tartarian buckwheat allergic individuals had IgE that reacted in Western blot with the purifed Fag t 2. | 29306152 | 1 | 2011-04-08 12:00:00 | 2020-05-14 17:18:43 | |
| Plantae Eudikotyledons | Caryophyllales | Fagopyrum tataricum | Tartarian buckwheat | 1050 | Fag t 6 | Oleosin | 18 kDa | 12 of 20 patients with claims of allergy to buckwheat in ingestion, inhalation or contact were positive in IgE binding to natural protein by western blot, dot blot and ELISA. Protein sequence was determined by LC-MS from SDS-PAGE | 34076413 | 1 | 2021-02-26 03:56:31 | 2021-07-10 07:34:49 | |
| Plantae Eudikotyledons | Fagales | Fagus sylvatica | European beech | 696 | Fag s 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 17 kDa | 2 | 2013-06-04 12:00:00 | 2019-08-16 22:52:52 | |||
| Animalia Chordata | Carnivora | Felis domesticus (F. catus) | Domestic cat | 319 | Fel d 1 | Uteroglobin (chain 1) | 38 kDa | cat-1 | >90% decrease in skin-test reactivity in cat-allergic patients was found after absorption of Fel d 1 from catdander extract. In RAST, a 76% reduction of IgE binding was found after depletion of Fel d 1 (medline 89054671). - recombinant chain 1 and chain 2: IgE binding in ELISA (medline 93254448) - IgE binding to nFel d 1 and rFel d 1 (medline 22304954) | 824067 | 2 | 2003-02-05 12:00:00 | 2019-08-17 02:21:38 |
| Animalia Chordata | Carnivora | Felis domesticus (F. catus) | Domestic cat | 320 | Fel d 2 | Serum albumin | 69 kDa | 14-23% of catallergic patients showed IgE binding to Fel d 2 in immunoblots | 9105522 | 2 | 2003-02-05 12:00:00 | 2019-08-16 23:00:20 | |
| Animalia Chordata | Carnivora | Felis domesticus (F. catus) | Domestic cat | 321 | Fel d 3 | Cystatin-A | 11 kDa | 60-90% of cat allergic patients showed IgE binding to rec. Fel d 3 in plaque immunoassay; 10% showed IgE binding in RAST | 11529899 | 2 | 2003-02-05 12:00:00 | 2020-05-14 23:43:35 | |
| Animalia Chordata | Carnivora | Felis domesticus (F. catus) | Domestic cat | 322 | Fel d 4 | Lipocalin | 22 kDa | 17 of 27 cat allergic subjects (62.96%) had IgE reactivity to rFel d 4 in the DELFIA assay. | 15544598 | 2 | 2006-02-25 12:00:00 | 2019-08-17 02:17:55 | |
| Animalia Chordata | Carnivora | Felis domesticus (F. catus) | Domestic cat | 323 | Fel d 5 | Immunoglobulin A | 400 kDa | 2 | 2006-02-25 12:00:00 | 2019-08-16 23:01:34 | |||
| Animalia Chordata | Carnivora | Felis domesticus (F. catus) | Domestic cat | 324 | Fel d 6 | Immunoglobulin M | 800-1000 kDa | 2 | 2006-02-25 12:00:00 | 2020-05-14 23:45:35 | |||
| Animalia Chordata | Carnivora | Felis domesticus (F. catus) | Domestic cat | 665 | Fel d 7 | lipocalin | 17.5 kDa | 2 | 2010-01-28 12:00:00 | 2020-05-14 23:46:01 | |||
| Animalia Chordata | Carnivora | Felis domesticus (F. catus) | Domestic cat | 702 | Fel d 8 | Latherin-like protein | 24 kDa | Among 109 cat-allergic individuals, the frequency of IgE binding was 37.6% to rFel d 7 and 19.3% to rFel d 8. | 21576986 | 2 | 2010-10-13 12:00:00 | 2020-05-14 23:47:02 | |
| Plantae Liliopsida (monocots) | Poales | Festuca pratensis | Meadow fescue | 325 | Fes p 4 | 60 kDa | ELISA to Festuca pratensis was inhibited up to 80% by F. pratensis pollen extract and up to 48% by purified Fes p 4. (8 sera tested). | 11206937 | 2 | 2003-02-11 12:00:00 | 2019-08-17 02:24:04 | ||
| Animalia Arthropoda | Diptera | Forcipomyia taiwana | Biting midge | 326 | For t 1 | Serine/threonine-protein kinase | 24 kDa | 6 of 12 (50%) F. taiwana allergic subjects showed IgE binding to For t 1 on the immunoblot of crude F. taiwana extract. | 16266384 | 4 | 2008-07-12 12:00:00 | 2019-08-17 02:38:01 | |
| Animalia Arthropoda | Diptera | Forcipomyia taiwana | Biting midge | 327 | For t 2 | Eukaryotic translation initiation factor 3 subunit | 36 kDa | 9 of 12 (75%) F. taiwana allergic subjects showed IgE binding to For t 2 on the immunoblot of crude F. taiwana extract. | 16266384 | 4 | 2008-07-12 12:00:00 | 2019-08-17 02:40:37 | |
| Plantae Eudikotyledons | Rosales | Fragaria ananassa | Strawberry | 328 | Fra a 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 18 kDa | 5 of 8 sera from strawberry allergic patients contained IgE binding to nFra a 1 in Western blot. | 15507096 16945416 | 1 | 2006-10-13 12:00:00 | 2020-05-14 17:20:05 | |
| Plantae Eudikotyledons | Rosales | Fragaria ananassa | Strawberry | 329 | Fra a 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | 28 strawberry allergic subjects were tested for IgE binding to proteins from strawberries. 16 of 17 had pollen allergy as well, 4 of 5 were DBPCFC to strawberry. Five of 17 were IgE positive to rFra 3 by RAST and confirmed by immunoblot (8 were +). Two IgE positive sera were tested using Basophil histamine release and were positive. | 16650053 | 1 | 2006-10-13 12:00:00 | 2019-08-17 02:42:53 | |
| Plantae Eudikotyledons | Rosales | Fragaria ananassa | Strawberry | 330 | Fra a 4 | Profilin | 13 kDa | 1 | 2006-10-13 12:00:00 | 2020-05-14 16:50:54 | |||
| Plantae Eudikotyledons | Lamiales | Fraxinus excelsior | European ash | 331 | Fra e 1 | Ole e 1-like protein family member | 20 kDa | Serum IgE from 13 out of 15 olive-allergic patients tested showed IgE reactivity to purified Fra e 1 in RAST. - 23 out of 40 ash pollen-allergic patients (57.5%) showed serum IgE binding to 21-25 kD protein on immunoblot of ash pollen extract. | 15696094 | 2 | 2004-10-27 12:00:00 | 2019-08-17 02:53:08 | |
| Fungi Ascomycota | Hypocreales | Fusarium culmorum | 332 | Fus c 1 | Ribosomal protein P2 | 11 kDa | Of 52 subjects with suspected mould allergy, 23 (44%) were found to contain F. culmorum-specific serum IgE antibodies. Of 26 F.culmorum-sensitized patient sera, 35% showed IgE binding to rFus c 1 on immunoblot. | 12695122 | 2 | 2003-08-31 12:00:00 | 2019-08-17 02:54:59 | ||
| Fungi Ascomycota | Hypocreales | Fusarium culmorum | 333 | Fus c 2 | Thioredoxin-like protein | 13 kDa | Of 52 subjects with suspected mould allergy, 23 (44%) were found to contain F. culmorum-specific serum IgE antibodies. Of 26 F.culmorum-sensitized patient sera, 50% showed IgE binding to rFus c 2 on immunoblot. | 12695122 | 2 | 2003-08-31 12:00:00 | 2019-08-17 02:55:58 | ||
| Fungi Ascomycota | Hypocreales | Fusarium proliferatum | 787 | Fus p 4 | Transaldolase | 37.5 kDa | Sera from 8 of 17 patients allergic to F. proliferatum had IgE that bound to the natural Fus p 4 in an immunoblot. This IgE-binding could be inhibited with the recombinant Fus p 4.0101 that had been produced in E. coli. | 25075521 | 2 | 2014-01-09 12:00:00 | 2024-06-28 18:38:34 | ||
| Fungi Ascomycota | Hypocreales | Fusarium proliferatum | 799 | Fus p 9 | Vacuolar serine protease | 36.5 kDa | Nine of seventeen respiratory atopic patients from Taipei who had IgE binding to proteins of Fusarium proliferatum, had IgE binding to the Vacuolar serine protease. The crude extract used for testing was from a combination of hyphae and spores. Specific IgE binding was tested with recombinant protein produced by a cDNA clone. | 27334782 | 2 | 2014-07-21 12:00:00 | 2019-08-17 03:01:32 | ||
| Animalia Chordata | Gadiformes | Gadus callarias | Baltic cod | 334 | Gad c 1 | Beta-parvalbumin | 12 kDa | Allergen M | Sera from all patients allergic to fish (n = 30) displayed IgE reactivity on immunoblot to parvalbumin (Gad c 1), a 12 kd protein present in codfish extract. | 9449503 | 1 | 2003-07-01 12:00:00 | 2019-08-27 01:07:34 |
| Animalia Chordata | Gadiformes | Gadus morhua | Atlantic cod | 708 | Gad m 1 | Beta-parvalbumin | 12 kDa | Allergen M | Sera from all 12 tested cod-allergic patients showed IgE-binding to Gad m 1 in ELISA. 5/5 sera bound to rGad m 1 in immunoblot. | 12431393 | 1 | 2011-01-25 12:00:00 | 2019-08-27 01:09:24 |
| Animalia Chordata | Gadiformes | Gadus morhua | Atlantic cod | 748 | Gad m 2 | Beta-enolase | 47.3 kDa | Sera of 35 of 62 individuals with a convincing history of fish allergy had IgE that reacted with natural purified Gad m 2 in ELISA. IgE of 4 of 5 patients tested produced postive RBL assays with Gad m 2. | 23786287 | 1 | 2012-07-30 12:00:00 | 2020-05-15 00:08:46 | |
| Animalia Chordata | Gadiformes | Gadus morhua | Atlantic cod | 749 | Gad m 3 | Aldolase A | 40 kDa | Sera of 23 of 62 fish allergic individuals had IgE that reacted with purified natural Gad m 3 in ELISA. IgE of 2 of 2 tested patients produced positive RBL assays with Gad m 3. | 23786287 | 1 | 2012-07-30 12:00:00 | 2020-05-15 00:09:49 | |
| Animalia Chordata | Galliformes | Gallus domesticus (G. gallus) | Chicken | 335 | Gal d 1 | Ovomucoid | 28 kDa | Of 33 patients allergic to egg white, 32 showed IgE binding to pure ovomucoid in RAST. | 6601671 | 1 | 2003-07-01 12:00:00 | 2019-08-27 01:30:57 | |
| Animalia Chordata | Galliformes | Gallus domesticus (G. gallus) | Chicken | 336 | Gal d 2 | Ovalbumin | 44 kDa | All 33 egg white-allergic patients tested, showed serum IgE binding to highly purified ovalbumin in RAST. | 6601671 | 1 | 2003-07-01 12:00:00 | 2019-08-27 01:31:06 | |
| Animalia Chordata | Galliformes | Gallus domesticus (G. gallus) | Chicken | 337 | Gal d 3 | Ovotransferrin | 78 kDa | Ag22 | Of 33 egg white-allergic patients tested, 31 showed IgE binding to highly purified conalbumin in RAST. - Both naive and denatured transferrin strongly bound patients IgE (8 egg white-allergic patients tested) in ELISA: medline 21956723. - Of 15 patients with positive skin prick test with hens egg white reference solution, 11 (73%) were positive in SPT with purified transferrin: medline 83201943. | 6601671 | 1 | 2003-07-01 12:00:00 | 2019-08-27 01:31:23 |
| Animalia Chordata | Galliformes | Gallus domesticus (G. gallus) | Chicken | 338 | Gal d 4 | Lysozyme C | 14 kDa | Of 33 egg white-allergic patients tested, 22 (67%) showed serum IgE binding to highly purified lysozyme in RAST. - Both naive and denatured lysozyme were recognized by patients IgE (8 egg white-allergic patients tested) in ELISA: medline 21956723. | 6601671 | 1 | 2003-07-01 12:00:00 | 2019-08-27 01:31:44 | |
| Animalia Chordata | Galliformes | Gallus domesticus (G. gallus) | Chicken | 339 | Gal d 5 | Serum albumin, alpha-livetin | 69 kDa | All 8 patients with food allergy to egg yolk and who suffered from respiratory symptoms upon exposure to birds, had positive skin responses to egg yolk and purified Gal d 5. In bronchial provocation test, Gal d 5 elicited early asthmatic responses in all 6 patients tested. 2 patients were positive in oral challenge test with Gal d 5. All 8 patients showed IgE binding to Gal d 5 in ELISA, and 7 on immunoblot of Gal d 5. | 11488669 | 1 | 2003-07-03 12:00:00 | 2025-08-25 16:38:16 | |
| Animalia Chordata | Galliformes | Gallus domesticus (G. gallus) | Chicken | 340 | Gal d 6 | YGP42 | 35 kDa | The Gal d 6 allergen, referred to by the authors Amo et al. in PMID 20509661, as YGP42. The allergen consists of the carboxy terminal 284 amino acids which are cleaved from the primary translation product of vitellogenin-1 found in Genbank entry D89547 and UNIPROT P87498 as described in the 2010 publication. Gal d 6 has three potential N-linked glycosylation sites and the apparent molecular weight is stated as approximately 35 kDa by the authors. | 20509661 | 1 | 2009-09-22 12:00:00 | 2019-08-27 01:32:30 | |
| Animalia Chordata | Galliformes | Gallus domesticus (G. gallus) | Chicken | 829 | Gal d 7 | Myosin light chain 1f | 22 kDa | 45 subjects with food allergy to ingestion of chicken by case history were tested for IgE binding in vitro, 23 of them had IgE binding to recombinant Myosin light chain by ELISA and 7 of 7 had IgE binding to reducing immunoblot. Poster presentation at the OGMBT annual meeting in Vienna, Austria. Poster PP-IA-07 C in 2014. Authors: Christoph Klug, Wolfgang Hemmer, Margit Focke, Santiago Quirce, Erwin Gaubitzer and Ines Swoboda | 27340614 | 1 | 2015-08-17 12:00:00 | 2019-08-27 01:38:09 | |
| Animalia Chordata | Galliformes | Gallus domesticus (G. gallus) | Chicken | 865 | Gal d 8 | alpha-parvalbumin | 11.8 kDa | Case history, in vitro IgE binding. E coli expressed protein. 22 of 36 were positive by in vitro IgE binding. 18/29 fish/chicken-allergic patients had IgE reacting to Gal d 8 (61%). | 19772518 27344988 | 1 | 2016-02-22 12:00:00 | 2020-05-15 00:31:12 | |
| Animalia Chordata | Galliformes | Gallus domesticus (G. gallus) | Chicken | 864 | Gal d 9 | Beta-enolase | 50 kDa | Case history for chicken and IgE tests and SPT. 27 of 26 subjects positive, and 4 of 5 by SPT with natural protein. 22/29 fish/chicken-allergic patients had IgE reacting to Gal d 9 (75%) | 27344988 | 1 | 2016-02-22 12:00:00 | 2020-05-15 00:33:08 | |
| Animalia Chordata | Galliformes | Gallus domesticus (G. gallus) | Chicken | 863 | Gal d 10 | Aldolase | Sera from 36 chicken allergic subjects: Defined by case history and in vitro IgE and SPT. 30 of 36 positive by IgE ELISA, 4 of 5 positive by SPT. 24/29 fish/chicken-allergic patients had IgE reacting to Gal d 10 (83%). | 27344988 | 1 | 2016-02-22 12:00:00 | 2020-05-15 00:34:10 | ||
| Animalia Arthropoda | Diptera | Glossina morsitans | Savannah tsetse fly | 669 | Glo m 5 | Tsetse antigen 5, CAP (cysteine-rich secretory proteins, antigen 5 and pathogenesis-related 1) protein superfamily member | 27 kDa | 4 | 2010-02-11 12:00:00 | 2020-03-23 21:11:27 | |||
| Plantae Eudikotyledons | Fabales | Glycine max | Soybean | 342 | Gly m 1 | Hydrophobic protein from soybean | 7 kDa | Of 32 patients who suffered from asthma attacks during unloading of soybean at the seaports, 90% showed serum IgE binding to an 8 kD shell protein on immunoblot. This protein was later identified as Gly m 1 (medline 95326747) | 1917110 | 2 | 2003-06-24 12:00:00 | 2023-11-02 17:53:22 | |
| Plantae Eudikotyledons | Fabales | Glycine max | Soybean | 343 | Gly m 2 | Defensin | 8 kDa | Purified Gly m 2 was recognized in immunoblot by serum IgE from all 5 tested patients suffering from asthma caused by airborne soybean hull dust. | 9146936 | 2 | 2003-06-25 12:00:00 | 2019-08-27 01:46:25 | |
| Plantae Eudikotyledons | Fabales | Glycine max | Soybean | 344 | Gly m 3 | Profilin | 14 kDa | Of 12 subjects with soy bean allergy, 8 (67%) showed IgE binding to rGly m 3 on immunoblot. | 10589015 | 1 | 2003-06-25 12:00:00 | 2019-08-27 01:47:16 | |
| Plantae Eudikotyledons | Fabales | Glycine max | Soybean | 345 | Gly m 4 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 17 kDa | 1371403 | 1 | 2006-11-03 12:00:00 | 2019-08-27 01:47:41 | ||
| Plantae Eudikotyledons | Fabales | Glycine max | Soybean | 346 | Gly m 5 | Beta-conglycinin (vicilin, 7S globulin) | see subunits | 1 | 2008-08-19 12:00:00 | 2019-08-27 01:48:12 | |||
| Plantae Eudikotyledons | Fabales | Glycine max | Soybean | 347 | Gly m 6 | Glycinin (legumin, 11S globulin) | see subunits | 1 | 2008-08-19 12:00:00 | 2019-08-27 01:49:10 | |||
| Plantae Eudikotyledons | Fabales | Glycine max | Soybean | 763 | Gly m 7 | Seed biotinylated protein; late embryogenesis abundant protein | 76.2 kDa | Sera 18 of 23 soybean allergic individuals had IgE that reacted with the purified natural Gly m 7 in ELISA. Blood samples of 6 of 17 soybean allergic patients resulted in basophil activation as quantified by the percenatge of CD63+ basophils. | 27108990 | 1 | 2012-09-24 12:00:00 | 2025-07-02 16:20:57 | |
| Plantae Eudikotyledons | Fabales | Glycine max | Soybean | 785 | Gly m 8 | 2S albumin | 28 kDa | 23763971, 24117462 | 1 | 2014-01-07 12:00:00 | 2019-08-27 01:56:23 | ||
| Animalia Arthropoda | Sarcoptiformes | Glycyphagus domesticus | Storage mite | 341 | Gly d 2 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 15 kDa | Of 17 G.domesticus positive patients, 16 showed IgE binding to rGly d 2 on immunoblot. | 11240953 | 2 | 2003-05-13 12:00:00 | 2023-11-09 13:29:48 | |
| Animalia Mollusca | Lepetellida | Haliotis laevigata x Haliotis rubra | Jade tiger abaolone | 892 | Hal l 1 | Tropomyosin | 33.4 kDa | Five of 9 individuals with case histories of allergy to consumption of crustacean shellfish and one after handling prawns were positive. All were positive for oyster ImmunoCAP with at least 0.35 kU. Tests were positive by IgE binding to abalone tropomyosin in reducing immunoblots. | 1 | 2017-02-03 13:04:22 | 2019-08-27 02:04:29 | ||
| Animalia Mollusca | Lepetellida | Haliotis midae | Perlemoen abalone | 348 | Hal m 1 | 49 kDa | On immunoblots of abalone extract, a 49 kD protein was recognized by 5 out of 17 sera from abalone-sensitive patients with a positive RAST to abalone extract. | 9389294 | 1 | 2003-08-14 12:00:00 | 2019-08-27 02:05:22 | ||
| Animalia Arthropoda | Coleoptera | Harmonia axyridis | Asian ladybeetle | 349 | Har a 1 | 10 kDa | Har a 1 bound IgE antibody in 65% (13/20) of 20 sera of patients allergic to ladybeetle by skin test | 17291858 | 2 | 2007-02-18 12:00:00 | 2019-08-27 02:07:27 | ||
| Animalia Arthropoda | Coleoptera | Harmonia axyridis | Asian ladybeetle | 350 | Har a 2 | aldehyde dehydrogenase | 55 kDa | Har a 2 bound IgE antibody in 75% (15/20) of 20 sera of patients allergic to ladybeetle by skin test | 17291858 | 2 | 2007-02-18 12:00:00 | 2019-08-27 02:08:12 | |
| Plantae Eudikotyledons | Asterales | Helianthus annuus | Sunflower | 351 | Hel a 1 | 34 kDa | 8 out of 14 patients with RAST values >3PRU/ml to Helianthus annuus, showed IgE binding to 34 kD protein in immunoblot of Helianthus annuus pollen extract. IgE binding to purified 34 kD protein in immunoblot (serumpool tested) | 7920032 | 2 | 2003-04-17 12:00:00 | 2019-08-27 02:09:30 | ||
| Plantae Eudikotyledons | Asterales | Helianthus annuus | Sunflower | 352 | Hel a 2 | Profilin | 14.7 kDa | Of 121 sera from sunflower pollen-allergic patients (RAST class >2), 30.5% showed IgE binding to natural and recombinant Hel a 2 in immunoblotting experiments. | 9798651 | 2 | 2003-04-17 12:00:00 | 2019-08-27 02:09:53 | |
| Plantae Eudikotyledons | Asterales | Helianthus annuus | Sunflower | 353 | Hel a 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | 1 | 2006-11-03 12:00:00 | 2019-08-27 02:10:30 | |||
| Plantae Eudikotyledons | Asterales | Helianthus annuus | Sunflower | 908 | Hel a 6 | Pectate Lyase | 42 kDa | Subjects used in these tests have airway allergy, presumably from sunflower pollen. Six negative controls were used in serum IgE tests and Skin Prick Tests (SPT). Fifty three patients from Kolkata, India were tested by serum IgE binding to purified natural protein, with 19 having positive binding. Seventy five subject were tested by SPT with 28 positive. Basophil activation was tested using 12 subjects, four of them gave positive responses. The three controls to basophil tests were negative. The protein was purified by chromatography and gel electrophoresis, and found to be 95% pure. LC-mass spectrometry identified five peptides matching protein accession number OTF85892.1 in teh GenBank Protein database. A publication is in progress. | 33214682 | 2 | 2017-12-11 18:27:20 | 2021-08-27 18:03:32 | |
| Plantae Eudikotyledons | Asterales | Helianthus annuus | Sunflower | 1124 | Hel a 15 | 2S albumin seed storage protein, SESA2-1 | 14 kDa | Sera from 30 subjects were tested. Among them, 17 patients were allergic to sunflower seeds (SFS), with SFS-specific IgE > 0.35 kU/L (ImmunoCAP). Control sera were from 13 patients tolerant to SFS but allergic to other foods. Eleven of 17 (65%) SFS-allergic but none of the 13 SFS-tolerant food-allergic patients had IgE to Hel a 15, as measured by ELISA with the natural purified allergen. | 38619510 | 1 | 2023-06-30 16:42:07 | 2024-04-16 14:23:01 | |
| Plantae Eudikotyledons | Asterales | Helianthus annuus | Sunflower | 1125 | Hel a 16 | 2S albumin seed storage protein, SESA20-2 | 15 kDa | Sera from 30 subjects were tested. Among them, 17 patients were allergic to sunflower seeds (SFS), with SFS-specific IgE > 0.35 kU/L (ImmunoCAP). Control sera were from 13 patients tolerant to SFS but allergic to other foods. Seven of 17 (41%) SFS-allergic but none of the 13 SFS-tolerant food-allergic patients had IgE to Hel a 16, as measured by ELISA with the natural purified allergen. | 38619510 | 1 | 2023-06-30 17:14:49 | 2024-04-16 14:24:04 | |
| Plantae Eudikotyledons | Asterales | Helianthus annuus | Sunflower | 1126 | Hel a 17 | 2S albumin seed storage protein, SFA-8 (SESA3) | 10 kDa | Sera from 30 subjects were tested. Among them, 17 patients were allergic to sunflower seeds (SFS), with SFS-specific IgE > 0.35 kU/L (ImmunoCAP). Control sera were from 13 patients tolerant to SFS but allergic to other foods. Nine of 17 (53%) SFS-allergic and 3 of 13 (23%) SFS-tolerant food-allergic patients had IgE to Hel a 17, as measured by ELISA with the natural purified allergen. | 38619510 | 1 | 2023-06-30 17:48:24 | 2024-04-16 14:22:24 | |
| Animalia Mollusca | Stylommatophora | Helix aspersa [Cornu aspersum] | Brown garden snail | 354 | Hel as 1 | Tropomyosin | 36 kDa | Both natural and recombinant purified Hel as 1 were recognized by IgE in 4 of 22 (18%) sera of patients with positive skin prick test and IgE to brown garden snail. | 12065908 | 1 | 2003-08-08 12:00:00 | 2019-08-27 02:11:45 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 355 | Hev b 1 | Rubber elongation factor | 14 kDa | PubMed:9389300: Of 140 patients with spina bifida (SB), 81% had IgE against nHev b 1, as measured by EAST. Of 105 health care workers (HCWs) allergic to latex, 52% had nHev b 1 specific IgE. In skin-prick test with nHev b 1, 10 of 14 patients with SB and 16 of 18 HCWs reacted to the allergen. - PubMed:8828541: None of 20 tested sera of latex-allergic adult patients tested showed IgE binding to nHev b 1 or rHev b 1 on immunoblot. However, both allergens were recognized by 2 serum pools (53 and 101 sera) of patients with SB. - PubMed:10691894: Hev b 1 was recognized in an IgE-ELISA by 10 of 31 (32%) sera from latex allergic HCWs and from 13 of 13 sera from latex allergic patients with SB. | 9389300,8828541,10691894 | 3 | 2003-07-03 12:00:00 | 2019-07-11 17:58:01 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 360 | Hev b 2 | beta-1,3-glucanase; glucan endo-1,3-beta-glucosidase, basic vacuolar isoform | 35, 36.5 and 38 kDa | Pubmed:9525455: Of 15 latex allergic patients, 6 (40%) reacted with purified nHev b 2 in immunoblot and ELISA. - PubMed:12372996: All sera of 34 latex sensitized patients also sensitized to nHev b 2 bound to three separated isoforms in ELISA. In immunoblot, only the glycosylated isoforms I and II, but not the non-glycosylated isoform III were recognized. In SPT, 3-4 of 7 patients reacted with the isoforms. | 9525455,12372996 | 3 | 2003-07-03 12:00:00 | 2019-07-17 18:36:27 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 361 | Hev b 3 | Small rubber particle protein (SRPP) | 24 kDa | PubMed:10691894: nHev b 3 was recognized in an IgE-ELISA by 10 of 31 (32%) sera from latex allergic HCWs and from 13 of 13 sera from latex allergic patients with SB. | 10691894 | 3 | 2003-07-03 12:00:00 | 2019-07-17 18:36:41 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 362 | Hev b 4 | Lecithinase homologue; GDSL lipase/esterase family member | 53-55 kDa | - Pubmed:10691894: nHev b 4 bound IgE from 20 of 31 (65%) latex allergic health care workers and 10 of 13 (77%) patients with spina bifida in ELISA. - Pubmed:12642845: Of 62 health care workers who had experienced immediate skin reactions to NRL gloves, 39% had positive SPT response to purified nHev b 4. - Pubmed:16297147: Chemical deglycosylation of nHev b 4 abolished IgE binding of 3 latex allergic patients sera. | 10691894,12642845,16297147 | 3 | 2003-07-03 12:00:00 | 2019-07-17 18:36:53 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 363 | Hev b 5 | Acidic protein, unknown function | 16 kDa | - PubMed:8810305: In a basophil activation test with passively sensitized basophils, 5 of 6 sera from nHev b 5-sensitized patients elicited histamine release with nHev b 5. | 8810305 | 3 | 2003-07-24 12:00:00 | 2019-07-17 18:37:28 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 364 | Hev b 6 | Hevein precursor | 20 kDa | - Of 22 health care workers who had experienced immediate skin reactions to NRL gloves, 63% had positive SPT response to purified Hev b 6.01 - On an immunoblot of crude latex extract, hev b 6.01 was recognized by serum IgE in 88.9% of 54 latex-sensitive patients tested: medline 22115012. - medline 9845845 | 12642845 | 3 | 2003-07-24 12:00:00 | 2019-08-27 02:13:39 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 365 | Hev b 7 | Patatin-like protein | 42 kDa | - Of 22 health care workers who had experienced immediate skin reactions to NRL gloves, 45% had positive SPT response to purified Hev b 7.01. - IgE binding to rHev b 7 on immunoblot and positive SPT in response to rHev b 7 in 15 patients: medline 20057823 | 12642845 | 3 | 2003-07-24 12:00:00 | 2019-08-27 02:13:49 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 366 | Hev b 8 | Profilin | 15 kDa | Natural and recombinant purified Hev b 8 gave positive intradermoreaction (ID) in 15/17 of Spina Bifida and 14/14 of latex-allergic patients. 42% of sera from latex-allergic patients had IgE titers of class 1 or higher by enzyme immunoassay, and 39% of them exhibited IgE binding by SDS-PAGE immunoblotting with any natural or recombinant Hev b 8 forms | 12169172 | 3 | 2003-07-24 12:00:00 | 2019-08-27 02:13:57 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 367 | Hev b 9 | Enolase | 51 kDa | 16 out of 110 latex-allergic patients (14.5%) revealed IgE binding to recombinant Hev b 9 in immunoblot. | 11106410 | 3 | 2003-07-24 12:00:00 | 2019-08-27 02:14:07 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 356 | Hev b 10 | Superoxide dismutase (Mn) | 26 kDa | In EAST, 0/20 sera from latex-allergic health care workers and 2/20 sera from latex-allergic patients with spina bifida showed IgE binding to recombinant Hev b 10. (Hev b 10.0103) | 11167363 | 3 | 2003-07-24 12:00:00 | 2019-08-27 02:14:16 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 357 | Hev b 11 | Class I chitinase | 30 kDa | 3 | 2003-07-24 12:00:00 | 2019-08-27 21:47:17 | |||
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 358 | Hev b 12 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | Of 37 latex-allergic patients tested, 9 (24%) showed IgE binding to recombinant Hev b 12 (as fusion protein) on immunoblot. | 12722968 | 3 | 2003-07-24 12:00:00 | 2019-08-27 02:14:35 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 359 | Hev b 13 | Esterase | 42 kDa | Of 62 health care workers with confirmed NRL allergy, 63% exhibited positive skin prick test responses to purified Hev b 13. | 12642845 | 3 | 2003-07-24 12:00:00 | 2019-08-27 02:14:44 | |
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 691 | Hev b 14 | Hevamine | 30 kDa | 3 | 2010-07-30 12:00:00 | 2019-08-27 21:37:58 | |||
| Plantae Eudikotyledons | Malpighiales | Hevea brasiliensis | Para rubber tree (latex) | 792 | Hev b 15 | Serine protease inhibitor | 7.5 kDa | 3 | 2014-04-24 12:00:00 | 2019-08-27 21:37:07 | |||
| Plantae Liliopsida (monocots) | Poales | Holcus lanatus | Velvet grass | 368 | Hol l 1 | Beta-expansin | 34 kDa | - >90% of velvet grass sensitive patients (50 tested) recognize recombinant allergen fragments on immunoblot. - 67% of patients (97 tested) recognize 34 kD protein on immunoblot of velvet grass pollen extract. see also medline 96319506 | 9215246 | 2 | 2003-02-11 12:00:00 | 2019-08-27 21:49:38 | |
| Plantae Liliopsida (monocots) | Poales | Holcus lanatus | Velvet grass | 369 | Hol l 5 | 30 kDa | - 64% of patients (97 tested) showed IgE binding to Hol l 5 on immunoblot of velvet grass pollen extract. - all patients (10 tested) showed IgE binding to rHol l 5 (rHol l 5.01 and rHol l 5.02) on immunoblot See also medline 98181862 | 8768803 | 2 | 2003-02-11 12:00:00 | 2019-08-27 21:50:10 | ||
| Animalia Arthropoda | Decapoda | Homarus americanus | American lobster | 370 | Hom a 1 | Tropomyosin | 34 kDa | Recombinant Hom a I was recognized by IgE from patients with crustacean allergies. When preabsorbed with rHom a I, sera lost their IgE reactivity to muscle extract of H. americanus. | 9597774 | 1 | 2003-06-24 12:00:00 | 2019-08-27 21:51:34 | |
| Animalia Arthropoda | Decapoda | Homarus americanus | American lobster | 371 | Hom a 3 | Myosin light chain 2 | ~23 kDa | 2/25 (8%) of shrimp allergic patients had IgE that reacted with Hom a 3 in IgE immunoblotting experiments. | 1 | 2009-01-23 12:00:00 | 2019-08-27 22:37:46 | ||
| Animalia Arthropoda | Decapoda | Homarus americanus | American lobster | 372 | Hom a 6 | Troponin C | ~20 kDa | 6/25 (24%) of shrimp allergic patients had IgE that reacted with Hom a 6 in IgE immunoblotting experiments. | 1 | 2009-01-23 12:00:00 | 2019-08-27 22:38:07 | ||
| Animalia Chordata | Primates | Homo sapiens | Human autoallergen | 373 | Hom s 1 | Squamous cell carcinoma antigen SART-1 | 55-60 kDa | Detection of circulating Hom s 1-IgE complexes in sera of 2 atopic dermatitis patients. IgE binding to natural and recombinant Hom s 1 on immunoblot. | 9856836 | 0 | 2003-08-14 12:00:00 | 2019-08-27 22:42:54 | |
| Animalia Chordata | Primates | Homo sapiens | Human autoallergen | 374 | Hom s 2 | Nascent polypeptide-associated complex alpha subunit | N.A. | 9806765 | 0 | 2003-08-14 12:00:00 | 2010-04-29 23:57:55 | ||
| Animalia Chordata | Primates | Homo sapiens | Human autoallergen | 375 | Hom s 3 | BCL7B protein | 22-23 kDa | Sera from 2 patients tested, suffering from atopic dermatitis, showed IgE binding to rHom s 3 on nitocellulose filter. In 2 out of 5 patients tested rHom s 3 induced immediate type skin reactions. | 9806765 | 0 | 2003-08-14 12:00:00 | 2019-08-27 22:43:05 | |
| Animalia Chordata | Primates | Homo sapiens | Human autoallergen | 376 | Hom s 4 | Atopy related autoantigen CALC | N.A. | Sera from 2 patients tested, suffering from atopic dermatitis, showed IgE binding to rHom s 4 on nitocellulose filter. In 1 out of 5 patients tested rHom s 4 induced immediate type skin reaction. | 9806765 | 0 | 2003-08-14 12:00:00 | 2010-04-29 23:57:55 | |
| Animalia Chordata | Primates | Homo sapiens | Human autoallergen | 377 | Hom s 5 | Keratin, type II cytoskeletal 6A | N.A. | Sera from 2 patients tested, suffering from atopic dermatitis, showed IgE binding to rHom s 5 on nitocellulose filter. In 1 out of 5 patients tested rHom s 5 induced immediate type skin reaction. | 9806765 | 0 | 2003-08-14 12:00:00 | 2025-08-25 16:39:06 | |
| Plantae Liliopsida (monocots) | Poales | Hordeum vulgare | Barley | 378 | Hor v 1 | deleted (identical to Hor v 15); designation reserved for beta-expansin pollen allergen | 1 | 2003-02-11 12:00:00 | 2019-08-27 22:51:28 | ||||
| Plantae Liliopsida (monocots) | Poales | Hordeum vulgare | Barley | 384 | Hor v 5 | 30 kDa | Hor v 9 | Hor v 5 was recognized in immunoblotting experiments by IgE antibody preparations from individuals allergic to barley pollen allergens | 7537171 | 2 | 2003-02-12 12:00:00 | 2019-08-27 22:45:45 | |
| Plantae Liliopsida (monocots) | Poales | Hordeum vulgare | Barley | 379 | Hor v 12 | Profilin | 14 kDa | No data found | 1 | 2003-03-25 12:00:00 | 2019-08-27 22:45:56 | ||
| Plantae Liliopsida (monocots) | Poales | Hordeum vulgare | Barley | 380 | Hor v 15 | Monomeric alpha-amylase inhibitor BMAI-1 | 14.5 kDa | A barley salt-soluble protein of 14.5 kDa, which inhibits the alpha-amylase from the insect Tenebrio molitor, has been identified as a major IgE-binding component of sera from bakers asthma patients. | 2785932 | 1 | 2003-10-27 12:00:00 | 2025-08-25 16:40:01 | |
| Plantae Liliopsida (monocots) | Poales | Hordeum vulgare | Barley | 381 | Hor v 16 | Alpha-amylase | no information found | 1 | 2003-10-27 12:00:00 | 2010-04-29 23:57:55 | |||
| Plantae Liliopsida (monocots) | Poales | Hordeum vulgare | Barley | 382 | Hor v 17 | Beta-amylase | no information found | 1 | 2003-10-27 12:00:00 | 2010-04-29 23:57:55 | |||
| Plantae Liliopsida (monocots) | Poales | Hordeum vulgare | Barley | 383 | Hor v 20 | Gamma-hordein 3 | 34 kDa | Hor v 21 | In ELISA, 21 out of 23 (91%) patients with wheat-dependent, exercise-induced anaphylaxis had IgE antibodies to purified gamma-3 hordein. Skin prick testing gave positive reactions to gamma-3 hordein in 7 out of 15 (47%) patients tested. | 12840704; 11260160 | 1 | 2003-02-12 12:00:00 | 2019-08-27 22:48:18 |
| Plantae Eudikotyledons | Rosales | Humulus japonicus | Japanese hop | 385 | Hum j 1 | 10 kDa | Twenty-two H. japonicus allergic subjects from Korea (72%) showed IgE reactivity to proteins of 10 kDa on immunoblots. In a Chinese study, 11 of 14 sera (79%) from H. japonicus-allergic patients (symptoms in late summer + positive ImmunoCAP to H. japonicus + positive SPT) had IgE specific to purified nHum j 1 and rHum j 1.0101 (expressed in E. coli) as determined by ELISA. | 10457112,40822751,40625753 | 2 | 2006-11-03 12:00:00 | 2025-09-04 16:11:39 | ||
| Plantae Eudikotyledons | Rosales | Humulus japonicus | Japanese hop | 1112 | Hum j 6 | Pectin methylesterase inhibitor (PMEI; pectinesterase inhibitor) | 10-15 kDa | Twenty-two patients with respiratory allergy who were sensitized to Japanese hop (specific IgE measured by ImmunoCAP) were tested. Of those, 19 (86%) had IgE to natural Hum j 6 purified from Humulus japonicus pollen as determined by ELISA. In contrast, recombinant allergens produced in E. coli Origami and Pichia pastoris bound only low amounts of IgE from 10 and 11 sera, respectively. The natural allergen is highly phosphorylated, but dephosphorylation did not affect IgE binding, as determined by immunoblot. | 37957794 | 2 | 2022-06-14 18:00:28 | 2024-10-04 17:51:36 | |
| Plantae Eudikotyledons | Fagales | Juglans nigra | Black walnut | 386 | Jug n 1 | 2S albumin seed storage protein | Ling,M., Ye,J., Cockrell,G., Sampson,H., Bannon,G.A., Stanley,J.S. and Burks,A.W. Characterization of Two Major Allergens in English and Black Walnut. Unpublished. | 1 | 2003-07-01 12:00:00 | 2010-04-29 23:57:55 | |||
| Plantae Eudikotyledons | Fagales | Juglans nigra | Black walnut | 387 | Jug n 2 | Vicilin seed storage protein; 7S globulin | Ling,M., Ye,J., Cockrell,G., Sampson,H., Bannon,G.A., Stanley,J.S. and Burks,A.W. Characterization of Two Major Allergens in English and Black Walnut. Unpublished. | 1 | 2003-07-01 12:00:00 | 2021-10-12 14:37:55 | |||
| Plantae Eudikotyledons | Fagales | Juglans nigra | Black walnut | 888 | Jug n 4 | Legumin-like seed storage protein; 11S globulin | 34 kDa, 22 kDa | Eight of 25 individuals with history of food allergy to tree nuts had positive IgE binding in reducing immunoblots to the purified natural this legumin. | 27936684 | 1 | 2016-12-20 10:01:15 | 2021-10-12 14:39:20 | |
| Plantae Eudikotyledons | Fagales | Juglans regia | English walnut | 388 | Jug r 1 | 2S albumin seed storage protein | 15-16 kDa | 12 of 16 patients with systemic allergic reactions to walnuts (75%) showed IgE binding to Jug r 1 (as a fusion protein with GST) in immunoblots of purified recombinant Jug r 1. epitope mapping of Jug r 1: medline 21657228 | 9648708 | 1 | 2003-03-27 12:00:00 | 2019-08-28 22:27:02 | |
| Plantae Eudikotyledons | Fagales | Juglans regia | English walnut | 389 | Jug r 2 | Vicilin (7S globulin) seed storage protein containing N-terminal alpha-hairpinin peptides | 44 kDa | A recombinant GST-fusion protein of full-length Jug r 2.0101 was shown to bind serum IgE from 9 of 15 patients tested | 10589017 | 1 | 2003-03-27 12:00:00 | 2025-04-30 16:01:39 | |
| Plantae Eudikotyledons | Fagales | Juglans regia | English walnut | 390 | Jug r 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | 42 of 46 (91.3%) of walnut allergic patients showed IgE binding to lipid transfer protein in walnut extract by immunoblotting. | 15480333 | 1 | 2003-03-27 12:00:00 | 2019-08-28 22:28:07 | |
| Plantae Eudikotyledons | Fagales | Juglans regia | English walnut | 391 | Jug r 4 | 11S globulin seed storage protein | 58.1 kDa | Serum IgE from 21 of 37 (57%) walnut allergic patients bound the rJug r 4 fusion protein on immunoblot. | 17032053 | 1 | 2007-02-08 12:00:00 | 2019-08-28 19:43:30 | |
| Plantae Eudikotyledons | Fagales | Juglans regia | English walnut | 876 | Jug r 5 | PR-10 | 20 kDa | Based on case history of allergy to English walnut, for those with + IgE binding by ImmunoCAP to recombinant E. coli produced protein (Walnut specific Immunocap to PR-10) and SPT (used Alyostal, Stallergens). Food challenges with DBPCFC 9 positive, open food challenge, 5 positive were both done using raw walnut from a local food market. seems to be due to primary sensitization to birch pollen allergy. But they have evidence this PR-10 is expressed in the nut and it was able to inhibit bindign to a 20 kDa IgE binding band in walnut extract. | 1 | 2016-06-26 12:00:00 | 2019-08-28 22:29:24 | ||
| Plantae Eudikotyledons | Fagales | Juglans regia | English walnut | 895 | Jug r 6 | 7S globulin seed storage protein, vicilin-like protein | 47 kDa | Sera from nineteen of 76 walnut sensitized subjects demonstrated IgE binding to natural purified protein of 47 kDa, identified as a vicilin-like sugar binding protein. Horse radish peroxidase was used as a CCD inhibiting protein in blocking as there is a glycan sequon. That did not inhibit binding significantly. Extract of hazelnut and natural Cor a 11 as well as Pistachio extract and sesame extract had high inhibition for a few sera by ELISA. | 30054513 | 1 | 2017-03-09 14:25:58 | 2022-04-29 16:00:03 | |
| Plantae Eudikotyledons | Fagales | Juglans regia | English walnut | 912 | Jug r 7 | Profilin | 13 kDa | 48 of 217 subjects from EuroPreval sensitive to walnut had IgE binding to recombinant (experimental ImmunoCAP). 97 of 217 were positive to walnut extract by SPT. Five negative controls. | 32916320 | 1 | 2017-12-21 06:02:26 | 2025-05-07 17:27:16 | |
| Plantae Eudikotyledons | Fagales | Juglans regia | English walnut | 924 | Jug r 8 | Non-specific lipid transfer protein type 2 (nsLTP2) | 9 kDa | Four of 10 walnut allergic subjects were positive in IgE binding to either natural or recombinant protein, expressed in Pichia. | 1 | 2018-04-10 04:43:44 | 2025-04-10 18:02:28 | ||
| Plantae Eudikotyledons | Fagales | Juglans regia | English walnut | 1183 | Jug r 9 | Phospholipase D alpha 1 | 92 kDa | Sera from 21 children with positive open oral food challenge with walnut and positive ImmunoCAP with walnut and Jug r 1 were tested. Of those, 5 (24%) had IgE to rJug r 9.0101 as determined by ELISA. | 41622977 | 1 | 2025-10-03 13:20:44 | 2026-02-02 14:31:17 | |
| Plantae Pinopsida | Cupressales | Juniperus ashei | Mountain cedar | 392 | Jun a 1 | Pectate lyase | 43 kDa | Jun s 1 | 10 out of 14 (71.4% of sera from mountain cedar-allergic patients showed IgE binding to purified Jun a 1 in ELISA. rJun a 1 was recognized on immunoblot by IgE of a serumpool from cedar-sensitive patients. | 10482835,725536 | 2 | 2003-04-02 12:00:00 | 2025-08-25 16:44:02 |
| Plantae Pinopsida | Cupressales | Juniperus ashei | Mountain cedar | 393 | Jun a 2 | Polygalacturonase | 43 kDa | IgE antibodies in sera of all 8 Japanese cypress-allergic patients tested and 1 mountain cedar-allergic patient tested bind to Jun a 2 in fluorometric assay. | 10944464 | 2 | 2003-04-02 12:00:00 | 2019-08-28 22:40:25 | |
| Plantae Pinopsida | Cupressales | Juniperus ashei | Mountain cedar | 394 | Jun a 3 | Thaumatin-like protein | 30 kDa | Of 14 mountain cedar-sensitive patients, 6 (42.9%) reacted with purified Jun a 3 in ELISA. | 10657673 | 2 | 2003-04-02 12:00:00 | 2019-08-28 22:41:27 | |
| Plantae Pinopsida | Cupressales | Juniperus ashei | Mountain cedar | 1008 | Jun a 7 | Gibberellin-regulated protein | 7 kDa | 16 of 16 subjects with Cupressaceae pollinosis and peach allergy were positive to natural purified proiten in ImmunoCAP | 2 | 2020-03-24 19:05:04 | 2020-03-25 00:44:00 | ||
| Plantae Pinopsida | Cupressales | Juniperus oxycedrus | Prickly juniper | 1093 | Jun o 1 | Pectate lyase | 40 kDa | Sera from 57 Spanish patients with rhino-conjunctivitis and sensitization to Cupressaceae pollen (positive SPT to J. oxycedrus and/or Cupressus arizonica and/or C. sempervirens) were tested. Of those, 48 (84%) had specific IgE to nJun o 1 as shown by ELISA. nJun o 1 cross-reacted with Cup a 1 and activated human mast cells sersitized with patients' sera. Enzymatic deglycosylation with PNGase A and PNGase F reduced IgE binding to nJun o 1 by 55% and 39%, respectively. In contrast, recombinant Jun o 1 purified from E. coli inclusion bodies failed to bind IgE and to activate mast cells. | 42095825 | 2 | 2022-03-23 19:56:26 | 2026-05-08 15:03:09 | |
| Plantae Pinopsida | Cupressales | Juniperus oxycedrus | Prickly juniper | 395 | Jun o 4 | Polcalcin-like protein (4 EF hand domains) | 29 kDa | Jun o 2 | Of 41 human sera from subjects allergic to Cupressaceae, 6 displayed IgE binding to rJun o 4 on immnublot. | 9648704 | 2 | 2003-04-02 12:00:00 | 2019-08-28 22:43:24 |
| Plantae Pinopsida | Cupressales | Juniperus sabinoides | Mountain cedar | 396 | Jun s 1 | Pectate lyase | Juniperus sabinoides is a synomym of J ashei. Therefore, data were moved to the entry Jun a 1. | Ten patients with cedar pollinosis tested all gave positive skin test results with purified (by gelfiltration) 50 kD protein. | 725536 | 2 | 2003-04-02 12:00:00 | 2025-08-25 16:43:20 | |
| Plantae Pinopsida | Cupressales | Juniperus virginiana | Eastern red cedar | 397 | Jun v 1 | Pectate lyase | 43 kDa | The IgE from 6 out of 13 sera of mountain cedar-allergic patients reacted with the 43 kD Jun v 1 on immunoblot; 12 of these sera reacted with a truncated/processed 30kD form of Jun v 1. | 11422137 | 2 | 2003-04-02 12:00:00 | 2019-08-28 22:46:01 | |
| Plantae Pinopsida | Cupressales | Juniperus virginiana | Eastern red cedar | 398 | Jun v 3 | Thaumatin-like protein | 10 kDa | 2 | 2003-04-08 12:00:00 | 2020-05-14 00:26:25 | |||
| Plantae Eudikotyledons | Caryophyllales | Kochia scoparia [Bassia scoparia] | Burning bush | 838 | Koc s 1 | Ole e 1- like protein | 18 kDa | SPT positive in 14 of 45 subjects using extract of pollen. IgE binding positive in 16 of 45 subjects using natural (extract?) and recombinant protein. | 10.12692/ijb/7.4.128-138 https://innspub.net/molecular-characterization-of-a-new-allergen-from-kochia-scoparia-pollen-koc-s-1/ | 2 | 2015-07-17 12:00:00 | 2024-09-13 15:49:56 | |
| Plantae Eudikotyledons | Caryophyllales | Kochia scoparia [Bassia scoparia] | Burning bush | 801 | Koc s 2 | Profilin | 14.5 kDa | 15 of 28 pollen allergic subjects were SPT positive with natural purified protein. 17 of 28 showed serum IgE binding in reducing immunoblots with natural and recombinant pure proteins. The experiments are well described in the J Korean Soc Appl Biol Chem (2015) 58(3):443-451. | 10.1007/s13765-015-0063-5 | 2 | 2014-08-18 12:00:00 | 2025-08-25 18:50:42 | |
| Plantae Eudikotyledons | Asterales | Lactuca sativa | Cultivated lettuce | 399 | Lac s 1 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | 10 of 14 (71%) showed IgE binding to Lac s 1 by immunoblotting | 12757453 | 1 | 2006-11-03 12:00:00 | 2025-04-10 18:16:05 | |
| Animalia Chordata | Acropomatiformes | Lateolabrax maculatus | Asian spotted seabass | 1159 | Late m 1 | Parvalbumin | 12 and 13 kDa | Sera from 5 fish-allergic patients (reported symptoms + sIgE to cod, salmon or bass measured by ImmunoCAP) were tested. All 5 sera had IgE to both isoforms of purified nLate m 1, as shown by IgE-immunoblot where the isoforms were separated. | 39198262 | 1 | 2024-11-11 15:20:09 | 2024-11-11 15:33:56 | |
| Animalia Chordata | Perciformes | Lates calcarifer | Barramundi | 776 | Lat c 1 | Beta-parvalbumin | 11.5 kDa | 15/18 fish allergic patients' sera had IgE that reacted with recombinant Lac c 1.0201 (produced in E. coli) in ELISA. 13/17 fish allergic patients' sera had IgE that reacted with recombinant Lac c 1.0201 (produced in E. coli) in Western blot. | 24973736 | 1 | 2014-11-13 12:00:00 | 2019-08-29 02:10:41 | |
| Animalia Chordata | Perciformes | Lates calcarifer | Barramundi | 955 | Lat c 6 | Collagen alpha | 130 kDa to 140 kDa | Lat c 6 Allergenicity: Sera of 87 fish-allergic patients were tested for IgE binding to a pool of barramundi, Atlantic salmon and Yellowfin tuna collagens by ELISA. 19 patients were positive. Of those, 13 sera were tested in immunoblots to check IgE binding to collagen from specific fish species and to specific collagen alpha chains. Of 13 sera tested in immunoblot, IgE from all 13 bound to collagen alpha 1 chain from muscle tissue of barramundi. 11 of 13 bound to alpha 2 chain from muscle and to alpha 1 and alpha 2 chains from skin. Basophil activation test was performed with whole blood of one of the collagen-sensitized patients, using barramundi muscle collagen as stimulant of basophils. The result was positive. | 32389794 | 1 | 2019-04-17 15:46:12 | 2021-01-02 21:29:42 | |
| Plantae Eudikotyledons | Fabales | Lens culinaris | Lentil | 400 | Len c 1 | Gamma-vicilin subunit | 47 kDa | Of 22 patients with lentil allergy, 15 (68%) showed IgE binding to purified Len c 1 on immunoblot. IgE binding to lentil extract was inhibited up to 64% by purified Len c 1 in CAP inhibition assay. | 11080720 | 1 | 2003-06-26 12:00:00 | 2019-08-29 02:18:03 | |
| Plantae Eudikotyledons | Fabales | Lens culinaris | Lentil | 401 | Len c 2 | Seed-specific biotinylated protein | 66 kDa | Of 22 lentil-allergic patients tested, 9 (41%) showed IgE binding to purified Len c 2 on immunoblot. IgE binding to Lentil extract was inhibited up to 45% by purified Len c 2 in CAP inhibition assay. | 11080720 | 1 | 2003-06-26 12:00:00 | 2019-08-29 02:18:26 | |
| Plantae Eudikotyledons | Fabales | Lens culinaris | Lentil | 684 | Len c 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | 1 | 2010-05-27 12:00:00 | 2025-04-10 18:16:30 | |||
| Animalia Arthropoda | Sarcoptiformes | Lepidoglyphus destructor | Sugar mite | 404 | Lep d 2 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 16 kDa (14 kDa non-red) | Lep d 1 | Of 24 L.destructor-sensitive patients tested, 21 showed IgE binding to purified Lep d 2 in RAST. Good correlation between IgE binding to L. destructor and Lep d 2 (r=0.74,PLESSTHAN0.0001). >75% inhibition of IgE binding (serumpool) to Ld by Lep d 2. | 1611545 | 2 | 2003-05-13 12:00:00 | 2023-11-09 13:30:10 |
| Animalia Arthropoda | Sarcoptiformes | Lepidoglyphus destructor | Sugar mite | 405 | Lep d 5 | Group 5/21 allergen | ~12.5 kDa | Of 45 L.destructor RAST-positive patients, 4 (9%) showed IgE binding to purified, recombinant Lep d 5 on immunoblot. | 11168362 | 2 | 2003-05-13 12:00:00 | 2023-11-09 14:23:22 | |
| Animalia Arthropoda | Sarcoptiformes | Lepidoglyphus destructor | Sugar mite | 406 | Lep d 7 | Bactericidal permeability-increasing like protein | 22 kDa | Of 45 L.destructor RAST-positive patients tested, 28 (62%) showed serum IgE binding to purified, recombinant Lep d 7 on immunoblot. | 11168362 | 2 | 2003-05-13 12:00:00 | 2025-08-25 16:44:42 | |
| Animalia Arthropoda | Sarcoptiformes | Lepidoglyphus destructor | Sugar mite | 402 | Lep d 10 | Tropomyosin | 40 kDa | The IgE-binding frequencies of recombinant Lep d 10 was 13% (18/136) among subjects with IgE reactivity to mites and/or crustaceans. | 12740526 | 2 | 2003-05-13 12:00:00 | 2019-08-29 02:24:10 | |
| Animalia Arthropoda | Sarcoptiformes | Lepidoglyphus destructor | Sugar mite | 403 | Lep d 13 | Cytosolic fatty acid-binding protein | 14.6 kDa | Of 45 L.destructor RAST-positive patients tested, 6 (13%) showed serum IgE binding to pure recombinant Lep d 13 on immunoblot. | 11168362 | 2 | 2003-05-13 12:00:00 | 2023-11-09 14:07:30 | |
| Animalia Chordata | Pleuronectiformes | Lepidorhombus whiffiagonis | Megrim, whiff, turbot fish | 408 | Lep w 1 | Beta-parvalbumin | 11.5 kDa | 1 | 2008-07-04 12:00:00 | 2019-08-29 07:24:26 | |||
| Animalia Arthropoda | Zygetoma | Lepisma saccharina | Silverfish | 407 | Lep s 1 | Tropomyosin | 36 kDa | 9 of 133 arthropods allergic patients had IgE binding to natural silverfish tropomyosin on immunoblot. | 15836758, 12119499 | 2 | 2006-11-05 12:00:00 | 2019-08-29 07:18:49 | |
| Plantae Eudikotyledons | Lamiales | Ligustrum vulgare | Common privet | 409 | Lig v 1 | Ole e 1-like protein family member | 20 kDa | Among a population of patients allergic to olive pollen, 40 patients with IgE to Ole e 1 were selected. In these patients, a positive correlation was found between the intensity of IgE binding to privet pollen allergen Lig v 1 in immunoblot and the level of specific IgE to olive pollen. rLig v 1 (clone L 10) was recognized by IgE in a pool of 4 sera from patients allergic to olive pollen. | 9027441 | 2 | 2003-04-02 12:00:00 | 2019-08-29 07:26:38 | |
| Plantae Eudikotyledons | Lamiales | Ligustrum vulgare | Common privet | 1077 | Lig v 2 | Profilin | 14.8 kDa | IgE binding with 20 subjects positive out of 45 subjects, and 20 negative controls. The recombinant protein tested positive in ELISA and immunoblotting. And 20 subjects were positive by SPT with the recombinant protein. | 2 | 2021-10-27 19:31:44 | 2022-04-29 15:25:21 | ||
| Plantae Eudikotyledons | Malpighiales | Linum usitatissimum | Flaxseed | 1046 | Lin u 1 | 2S albumin, conlinin | 13 kDa; 10 kDa and 3 kDa reducing | Four of five subjects with history of severe food allergy following consumption of flaxseed had IgE binding to the 2S albumin, conlinin, natural protein. | 29461213 | 1 | 2020-12-15 19:26:01 | 2025-08-25 18:56:15 | |
| Animalia Arthropoda | Psocoptera | Liposcelis bostrychophila | Booklouse | 703 | Lip b 1 | unknown function | 26 kDa | 12 of 33 booklice sensitized individuals with allergic asthma had IgE that reacted with a 26 kDa band by 1D blots of extracts (natural Lip b 1) and a pool of three subjects had IgE to the protein identified by sequencing from 2 dimensional immunoblots, with 24 amino acids. | 22123223, 27873335 | 2 | 2010-10-17 12:00:00 | 2024-07-09 17:54:38 | |
| Plantae Eudikotyledons | Sapindales | Litchi chinensis | Lychee | 410 | Lit c 1 | Profilin | 15 kDa | Specific IgE against lychee fruits were detected by an EAST assay. The allergen was characterized by immunoblot, immunoblot inhibition and EAST inhibition assays. Broad crossreactivity between lychee fruit and other plants was found and profilin identified as the protein responsible for the patients complex allergy syndrome. | 8556556 | 1 | 2003-08-08 12:00:00 | 2019-08-29 07:32:50 | |
| Animalia Arthropoda | Decapoda | Litopenaeus vannamei | White shrimp | 411 | Lit v 1 | Tropomyosin | 36 kDa | 15 of 15 (100%) shrimp allergic patients (confirmed by positive oral food challenge and SPTs) recognized Lit v 1 by peptide microarray analysis. | 22192087 | 1 | 2008-01-31 12:00:00 | 2019-08-29 07:49:14 | |
| Animalia Arthropoda | Decapoda | Litopenaeus vannamei | White shrimp | 412 | Lit v 2 | Arginine kinase | 40 kDa | 5 of 5 (100%) shrimp-allergic patients were tested positive by ELISA against purified L. vannamei arginine kinase. | 17496423 | 1 | 2007-02-08 12:00:00 | 2019-08-29 07:53:29 | |
| Animalia Arthropoda | Decapoda | Litopenaeus vannamei | White shrimp | 413 | Lit v 3 | Myosin, light chain 2 | 20 kDa | Recognized by 21/38 (55%)of shrimp allergic subjects by Western blot analysis and by a pool of 10 sera in 2d blot. The rLit v 3 was recognized by 10/13 shrimp allergic subjects. | 18760458 | 1 | 2008-03-25 12:00:00 | 2019-08-29 07:56:05 | |
| Animalia Arthropoda | Decapoda | Litopenaeus vannamei | White shrimp | 414 | Lit v 4 | Sarcoplasmic calcium-binding protein | 20 kDa | 52 adult and pediatric shellfish-allergic subjects with a history of immediate allergic reactions after ingestion of shrimp and positive serum IgE to shrimp by Immuno CAP (Phadia) were tested for IgE reactivity to boiled L. vannamei extract. 31 of them recognized a protein of approximately 20 kDa. The protein of interest was analysed by MS/MS from 2D gels and identified as shrimp sarcoplasmic calcium-binding protein. | 19523674 | 1 | 2009-01-22 12:00:00 | 2019-08-29 07:58:02 | |
| Animalia Arthropoda | Decapoda | Litopenaeus vannamei | White shrimp | 1079 | Lit v 13 | Cytosolic fatty acid binding protein | 15 kDa | 10 of 36 shrimp allergic subjects with Dr. diagnosis tested positive for IgE for IgE binding to recombinant protein, by ELISA using recombinant FABP on plate, and 5 were SPT psitive to extract and 3 were SPT positive to protein by basophil activation by flow cytometry. | 34695231 | 1 | 2021-11-05 15:56:35 | 2024-10-09 16:04:42 | |
| Plantae Liliopsida (monocots) | Poales | Lolium perenne | Rye grass | 415 | Lol p 1 | Beta-expansin | 27 kDa | Rey I | Lol pI expressed in bacteria as a fusion protein shows recognition by specific IgE antibodies present in sera of grass pollen-allergic subjects. - 17 out of 20 patients sensitized for Lolium perenne show IgE binding to Lol p 1 in RIA. See also medline 88060167 | 2001733 | 2 | 2003-02-12 12:00:00 | 2019-08-29 07:59:27 |
| Plantae Liliopsida (monocots) | Poales | Lolium perenne | Rye grass | 417 | Lol p 2 | Expansin-like protein homologous to the C-terminal expansin domain | 11 kDa | Rey II, Lol p II | 10 out of 20 patients sensitized for Lolium perenne show IgE binding to Lol p 2 in RIA | 3680810 | 2 | 2003-02-12 12:00:00 | 2025-08-25 16:45:48 |
| Plantae Liliopsida (monocots) | Poales | Lolium perenne | Rye grass | 418 | Lol p 3 | 11 kDa | Among 202 Lolium perenne allergic patients, 53 (26.2%) had IgE antibodies against Lol p 3. | 2496037 | 2 | 2003-02-12 12:00:00 | 2019-08-29 08:01:41 | ||
| Plantae Liliopsida (monocots) | Poales | Lolium perenne | Rye grass | 419 | Lol p 4 | FAD-binding oxidoreductase | 57 kDa | HMBA, Lol p IV | Lol p 4 elicits immediate skin reactions in grass allergic patients. Moreover, all patients sera tested had IgE antibodies to Lol p 4 detectable by direct RAST with Lol p 4 allergosorbent discs. | 6865958 | 2 | 2003-02-13 12:00:00 | 2025-08-25 16:47:25 |
| Plantae Liliopsida (monocots) | Poales | Lolium perenne | Rye grass | 420 | Lol p 5 | 31 kDa | Lol p IX, Lol p Ib | Natural- and rLol p 5 were recognized on immunoblot by IgE antibodies from pooled sera of grass pollen-allergic patients. | 1671715 | 2 | 2003-02-13 12:00:00 | 2025-08-25 16:47:49 | |
| Plantae Liliopsida (monocots) | Poales | Lolium perenne | Rye grass | 416 | Lol p 11 | Ole e 1-related protein | 16 kDa | A panel of 270 grass pollen-positive sera was assessed in a RAST with the purified allergen. More than 65% of grass pollen-positive sera had IgE against Lol p 11. | 7751518 | 2 | 2003-02-17 12:00:00 | 2019-08-29 08:08:14 | |
| Plantae Eudikotyledons | Fabales | Lupinus albus | white lupine | 891 | Lup a 5 | Profilin | 15 kDa | Six subjects with a case history of food allergy either to lupine (1/6 proven by food challenge) or to peanut with a suspected lupine allergy (5/6) were tested IgE positive by immunoblot analysis with the recombinant profilin. One additional patient with severe peanut and suspected lupine allergy was positive only in lupine extract. | 33525401 | 1 | 2017-01-29 14:26:42 | 2021-02-03 17:18:34 | |
| Plantae Eudikotyledons | Fabales | Lupinus angustifolius | Narrow-leaved blue lupin | 421 | Lup an 1 | Conglutin beta (7S seed storage globulin, vicilin) | 55-61 kDa | 9 of 12 lupin seed-allergic individuals have IgE that recognized Lup an 1. | 18620408 | 1 | 2008-01-28 12:00:00 | 2019-08-29 08:15:16 | |
| Plantae Eudikotyledons | Fabales | Lupinus angustifolius | Narrow-leaved blue lupin | 991 | Lup an 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 11 kDa | Six of 9 subjects with lupine and/or peanut allergy had IgE binding to this protein. Three were challenged with lupine flour and developed symptoms, four others had convincing history of peanut allergy plus strong suspected lupine allergy although only one of those was clearly positive with IgE binding to LTP under reducing conditions. Another one had weak IgE to LTP. | 33525401 | 1 | 2019-11-25 01:14:05 | 2025-04-10 18:17:02 | |
| Plantae basal Mesangiosperms | Proteales | Macadamia integrifolia | Macadamia | 1016 | Mac i 1 | Vicilin | 50 kDa | Sera of 8 Macadamia nut allergic subjects were tested for IgE binding to purified natural protein by ELISA and four were positive. The protein was confirmed by LC-MSMS. There is a Pro-peptide of ~ 179 AA, and the mature peptide from 180-625 AA. The submitters indicate the protein is glycosylated, but the glycan does not bind IgE, the protein does. | 34525424 | 1 | 2020-08-26 01:11:52 | 2023-03-28 17:52:25 | |
| Plantae basal Mesangiosperms | Proteales | Macadamia integrifolia | Macadamia | 1020 | Mac i 2 | Legumin | 60 kDa non reducing; 20 kDa and 40 kDa reducing | Eight patients with food allergy to Macadamia nut were tested for IgE binding, 6 were positive by ELISA, at least 2 by Immunoblot, using natural protein. | 34525424 | 1 | 2020-09-13 18:06:33 | 2023-03-28 17:49:28 | |
| Animalia Arthropoda | Decapoda | Macrobrachium rosenbergii | giant freshwater prawn | 780 | Mac r 1 | tropomyosin | 37 kDa | Ten of 13 shrimp-allergic Thai children had serum-specific IgE against Mac r1.0101 by ELISA. | 27001653 | 1 | 2013-09-11 12:00:00 | 2019-08-29 08:28:37 | |
| Animalia Arthropoda | Decapoda | Macrobrachium rosenbergii | giant freshwater prawn | 1076 | Mac r 2 | Arginine Kinase | 40 kDa | 48 prawn allergic patients were tested with prawn extract and all showed positive cutaenous respoens. IgE co-sensitization was evident in many with HDM, Squid and cockroaches. Specific IgE binding in dot blots and ELISA in 9 subjects | 1 | 2021-09-21 23:51:46 | 2021-09-21 23:52:09 | ||
| Fungi Basidiomycota | Malasseziales | Malassezia furfur | Skin-colonizing yeast | 429 | Mala f 2 | Peroxysomal membrane protein | 21 kDa | MF1 | Of 127 atopic dermatitis patients screened, 64 (50.4%) patients showed IgE binding to M.furfur extract in RAST. Of these 64 subjects, 46 (71.9%) showed IgE binding to Mala f 2. | 9675120 | 3 | 2003-09-01 12:00:00 | 2019-08-29 08:35:52 |
| Fungi Basidiomycota | Malasseziales | Malassezia furfur | Skin-colonizing yeast | 430 | Mala f 3 | Peroxysomal membrane protein | 20 kDa | MF2 | Of 127 atopic dermatitis patients screened, 64 (50.4%) patients showed IgE binding to M.furfur extract in RAST. Of these 64 subjects, 45 (70.3%) showed IgE binding to Mala f 3. | 9675120 | 3 | 2003-09-01 12:00:00 | 2019-08-29 23:48:40 |
| Fungi Basidiomycota | Malasseziales | Malassezia furfur | Skin-colonizing yeast | 431 | Mala f 4 | Mitochondrial malate dehydrogenase | 35 kDa | Thirty of 36 M. furfur-allergic atopic dermatitis patients (83.3%) had elevated serum levels of IgE to purified Mal f 4, indicating that Mal f 4 is a major allergen. There was a significant correlation of the Phadebas RAST unit values of Mal f 4 and the crude antigen. | 10103045 | 3 | 2003-09-01 12:00:00 | 2019-08-29 23:54:03 | |
| Fungi Basidiomycota | Malasseziales | Malassezia sympodialis | Skin-colonizing yeast | 432 | Mala s 1 | 37 kDa | 19 of 97 (20%) atopic eczema patients had positive SPT results to rMala s 1. | 16778796 | 3 | 2006-02-26 12:00:00 | 2019-08-30 00:47:48 | ||
| Fungi Basidiomycota | Malasseziales | Malassezia sympodialis | Skin-colonizing yeast | 437 | Mala s 5 | 18 kDa | 23 of 97 (24%) atopic eczema patients had positive SPT results to rMala s 5. | 16778796 | 3 | 2006-02-26 12:00:00 | 2019-08-30 01:00:36 | ||
| Fungi Basidiomycota | Malasseziales | Malassezia sympodialis | Skin-colonizing yeast | 438 | Mala s 6 | Cyclophilin | 17 kDa | 20 of 97 (21%) atopic eczema patients had positive SPT results to rMala s 6. | 16778796 10469297 | 3 | 2006-02-26 12:00:00 | 2020-05-14 17:53:33 | |
| Fungi Basidiomycota | Malasseziales | Malassezia sympodialis | Skin-colonizing yeast | 439 | Mala s 7 | 16 kDa | Of 25 Malassezia RAST positive atopic dermatitis patients 60% were positive to rMala s 7 by RAST, and 40% were positive by immunoblotting. From PMID 16778796: 3 of 97 (3%) atopic eczema patients had positive SPT results to rMala s 7. | 16778796 | 3 | 2006-02-26 12:00:00 | 2019-08-30 01:01:32 | ||
| Fungi Basidiomycota | Malasseziales | Malassezia sympodialis | Skin-colonizing yeast | 440 | Mala s 8 | 19 kDa | Of 25 Malassezia RAST positive atopic dermatitis patients 72% were positive to rMala s 8 by RAST, and 40% were positive by immunoblotting. From pmid 16778796: 8 of 97 (8%) atopic eczema patients had positive SPT results to rMala s 8. | 16778796 | 3 | 2006-02-26 12:00:00 | 2019-08-30 01:01:43 | ||
| Fungi Basidiomycota | Malasseziales | Malassezia sympodialis | Skin-colonizing yeast | 441 | Mala s 9 | 36.7 kDa | Of 25 Malassezia RAST positive atopic dermatitis patients 36% were positive to rMala s 9 by RAST, and 24% were positive by immunoblotting. PMID 16778796: 23 of 97 (24%) atopic eczema patients had positive SPT results to rMala s 9. | 16778796 | 3 | 2006-02-26 12:00:00 | 2019-08-30 00:57:33 | ||
| Fungi Basidiomycota | Malasseziales | Malassezia sympodialis | Skin-colonizing yeast | 433 | Mala s 10 | heat shock protein 70 | 86 kDa | 69% of 28 atopic dermatitis patients had IgE to rMala s 10 by ELISA. | 15128298 | 3 | 2004-04-18 12:00:00 | 2019-08-30 00:39:22 | |
| Fungi Basidiomycota | Malasseziales | Malassezia sympodialis | Skin-colonizing yeast | 434 | Mala s 11 | manganese superoxide dismutase | 23 kDa | 75% of 28 atopic dermatitis patients had IgE to rMala s 11 by ELISA. | 15128298 | 3 | 2004-04-18 12:00:00 | 2019-08-30 00:37:58 | |
| Fungi Basidiomycota | Malasseziales | Malassezia sympodialis | Skin-colonizing yeast | 435 | Mala s 12 | glucose-methanol-choline (GMC) oxidoreductase | 67 kDa | Recombinant Mala s 12 was recognized by serum IgE from 13 of 21 (62%) M. sympodialis-sensitized atopic eczema patients.” | 17313403 | 3 | 2006-02-26 12:00:00 | 2019-08-30 00:36:30 | |
| Fungi Basidiomycota | Malasseziales | Malassezia sympodialis | Skin-colonizing yeast | 436 | Mala s 13 | Thioredoxin | 13 kDa | Of 40 individuals suffering from AE and sensitized to M. sympodialis, 50% showed IgE binding to rMala s 13, as detected by ELISA. | 17182577 | 3 | 2006-02-26 12:00:00 | 2019-08-30 00:23:10 | |
| Plantae Eudikotyledons | Rosales | Malus domestica | Apple | 425 | Mal d 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 17.5 kDa | Of 9 sera from apple allergic patients tested, all showed IgE binding to Mal d 1 on immunoblot of apple extract; 8 sera showed IgE binding to rMal d 1. | 7677763 | 1 | 2003-04-17 12:00:00 | 2019-08-29 08:31:42 | |
| Plantae Eudikotyledons | Rosales | Malus domestica | Apple | 426 | Mal d 2 | Thaumatin-like protein | 23 kDa | Purified recombinant Mal d 2 displayed the ability to bind IgE from apple-allergic individuals equivalent to natural Mal d 2. | 12787673 | 1 | 2003-04-17 12:00:00 | 2019-08-29 08:32:27 | |
| Plantae Eudikotyledons | Rosales | Malus domestica | Apple | 427 | Mal d 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | A 13-kDa protein band was recognized in immunoblot of crude apple extract by 9 of 10 sera from patients allergic to fruit. | 10069888 | 1 | 2003-04-22 12:00:00 | 2019-08-29 08:33:30 | |
| Plantae Eudikotyledons | Rosales | Malus domestica | Apple | 428 | Mal d 4 | Profilin | N.A. | GD4-1 | 1 | 2003-04-22 12:00:00 | 2010-04-29 23:57:55 | ||
| Plantae Eudikotyledons | Sapindales | Mangifera indica | Mango | 1087 | Man i 1 | Class IV chitinase | 28 kDa | Sera from 67 patients with mango allergy (symptoms) were tested with natural and recombinant Man i 1, which yielded positive reactions with 35/67 (52%) and 23/65 (35%) sera, respectively. In the subgroup of patients with mango ImmunoCAP > 0.35 kU/L, the rates of positive reactions were with natural and recombinant Man i 1 were 17/30 (57%) and 9/29 (31%), respectively. | 36724175 | 1 | 2022-02-23 23:09:08 | 2023-04-03 18:49:22 | |
| Plantae Eudikotyledons | Sapindales | Mangifera indica | Mango | 1090 | Man i 2 | PR-10 protein; Bet v 1-related protein | 17 kDa | Of 31 patients with mango allergy according to history, 6 (19%) had IgE to rMan i 2.0101. In the subgroup of 15 patients with mango ImmunoCAP > 0.35 kU/L, only 1 serum (7%) showed a positive reaction. | 36724175 | 1 | 2022-02-23 23:56:51 | 2023-04-03 16:37:20 | |
| Plantae Eudikotyledons | Sapindales | Mangifera indica | Mango | 1088 | Man i 4 | Profilin | 14 kDa | Sixty-one sera from mango-allergic patients (as defined by history) were tested by IgE-ELISA. Of those, 24 (39%) had IgE to rMal i 4.0101. In the subgroup of 26 patients with mango ImmunoCAP > 0.35 kU/L, 16 (62%) were sensitized to Man i 4.0101. IgE-levels to Man I 4.0101 correlated with IgE to Art an 4.0101 (profilin from sweet wormwood pollen). 12 sera from mango allegric patients who were sensitized to Man i 4.0101 were also tested with rMan i 4.0102 by IgE ELISA. All sera also reacted to Man i 4.0102, albeit with significantly lower signals. | 36724175 | 1 | 2022-02-23 23:41:52 | 2023-04-03 18:37:02 | |
| Plantae Eudikotyledons | Malpighiales | Manihot esculenta | Cassava, manioc | 726 | Man e 5 | Glutamic acid rich protein | 30 kDa (anomalous migration due to high P and E content) | Among Brazilian patients allergic to manioc and latex, 5 out of 7 subjects (71.4%) demonstrated a positive IgE reactivity to the purified rMan e 5 and all 7 were positive to Hev b 5. From 30 Italian patients allergic to latex, initially selected for reactivity against Hev b 5, 12 (40%) were IgE positive to rMan e5 in ELISA. | 23526605 | 1 | 2011-04-13 12:00:00 | 2019-08-30 01:10:26 | |
| Animalia Arthropoda | Decapoda | Melicertus latisulcatus | King prawn | 800 | Mel l 1 | Tropomyosin | 38 kDa | Eighteen subjects with positive SPT to shrimp donated serum and serum IgE tests to this native purified tropomyosin was positive in 9 of 18, tests with this recombinant tropomyosin was positive in 10 of 18 sera all by immunoblotting. | 1 | 2014-08-14 12:00:00 | 2019-08-30 01:11:59 | ||
| Plantae Eudikotyledons | Malpighiales | Mercurialis annua | Annual mercury | 442 | Mer a 1 | Profilin | 14.1 kDa; 15.8 kDa | Of 37 sera with RAST values > 3 to M. annua pollen extract, 22 and 29 (51% and 59%) showed IgE binding to bands at 14.1 and 15.8 kDa on an immunoblot of M.annua pollen extract. These bands were identified as nMer a 1 by Western blot with a rabbit anti-profilin antibody (PubMed: 9104791). | 9104791,9525453 | 2 | 2007-09-25 12:00:00 | 2020-05-13 21:00:57 | |
| Animalia Chordata | Rodentia | Mesocricetus auratus | Golden hamster, Syrian hamster | 825 | Mes a 1 | lipocalin | ~20.5kDa, ~24kDa, ~30kDa - native form and ~22kDa recombinant form | 4 out of 6 patients showed positive IgE binding using natural form of protein in a reducing immunoblot. 2 out of 3 patients showed positive skin prick test results. 5 out of 6 patients showed positive IgE binding using natural form of protein in ELISA. 5 out of 6 patients showed positive IgE binding using recombinant form of protein in ELISA. | 25765367 | 2 | 2015-11-10 12:00:00 | 2019-08-30 01:21:55 | |
| Animalia Arthropoda | Decapoda | Metapenaeus ensis | Shrimp | 443 | Met e 1 | Tropomyosin | 34 kDa | Serum antibodies from patients with shrimp allergy demonstrated positive IgE reactivity by immunoblotting to a protein encoded by the clone Met e I | 7963157 | 1 | 2003-10-27 12:00:00 | 2019-08-30 01:23:13 | |
| Plantae Eudikotyledons | Rosales | Morus alba | White mulberry | 1044 | Mor a 2 | Cobalamin-independent methionine synthase | 84 kDa | Eleven subjects in Turkey with inhalation allergen and positive SPT to mulberry pollen extract (although 7 were late phase reactors) were tested for IgE binding to white mulberry pollen protein by western blot. The protein was cloned by PCR. The natural protein was confirmed by mass spectrometry. 11 of 11 were positive for IgE reactivity. results were reported in a scientific meeting in Turkey in 2018. | 2 | 2020-12-07 16:57:30 | 2020-12-07 20:01:46 | ||
| Plantae Eudikotyledons | Rosales | Morus nigra | Black mulberry | 444 | Mor n 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | IgE prevalence: 2/2 of patients with allergy to mulberry and 9/9 of patients with allergy to peach had IgE to natural purified Mor n 3 in Western Blot. Natural purified Mor n 3 induced positive SPTs in 18/25 Pru p 3 symptomatic patients. | 19958316 | 1 | 2009-05-27 12:00:00 | 2019-08-30 01:26:18 | |
| Animalia Chordata | Rodentia | Mus musculus | House mouse | 450 | Mus m 1 | Lipocalin and urinary prealbumin | 17 kDa | MUP6 | 1 patient tested showed serum IgE binding to Mus m 1 on immunoblot. Basophil histamine release of individuals sensitive to mice was induced with 17 kD protein. All 15 mouse-allergic subjects (positive in mouse RAST) tested showed serum IgE binding to Mus m 1 in XRIE. | 11468000,22041937 | 2 | 2003-02-05 12:00:00 | 2020-05-14 23:48:53 |
| Plantae Liliopsida (monocots) | Zingiberales | Musa acuminata | Banana | 445 | Mus a 1 | Profilin | 15 kDa | Mus xp 1 | 7 out of 16 sera (44%) from patients with suspected banana-allergy showed IgE binding to purified rMus xp 1 on immunoblot. | 12065910 | 1 | 2009-07-16 12:00:00 | 2019-08-30 01:27:59 |
| Plantae Liliopsida (monocots) | Zingiberales | Musa acuminata | Banana | 446 | Mus a 2 | Class 1 chitinase | 33 kDa | The purified allergens provoked positive SPT in more than 50% of the 8 banana-allergic patients. | 10231328 | 1 | 2008-11-18 12:00:00 | 2019-08-30 01:35:50 | |
| Plantae Liliopsida (monocots) | Zingiberales | Musa acuminata | Banana | 447 | Mus a 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | 20% of 36 banana allergic individuals had IgE that bound to the natural Mus a 3 in Western blot. 86% (31/36) of individual sera showed specific IgE binding to the purified homologous peach allergen Pru p 3 in an ELISA. | 1 | 2009-11-30 12:00:00 | 2019-08-30 01:39:59 | ||
| Plantae Liliopsida (monocots) | Zingiberales | Musa acuminata | Banana | 448 | Mus a 4 | Thaumatin-like protein | 20 kDa | 72% of 51 sera from pediatric patients with banana allergy showed IgE-binding to purified natural Mus a 4 in ELISA. | 21284746 | 1 | 2009-11-30 12:00:00 | 2019-08-30 01:48:57 | |
| Plantae Liliopsida (monocots) | Zingiberales | Musa acuminata | Banana | 449 | Mus a 5 | Beta-1,3-glucanase | 30 kDa | Purified natural Mus a 5 bound IgE of 84% of the sera from 51 pediatric patients with banana allergy. 17 (74%) of 23 patients were reactive to purified Mus a 5 analyzed by ELISA. | 21284746, 22162266 | 1 | 2009-11-27 12:00:00 | 2019-08-30 01:47:56 | |
| Plantae Liliopsida (monocots) | Zingiberales | Musa acuminata | Banana | 844 | Mus a 6 | ascorbate peroxidase | 27 kDa | Subjects in Thailand with case reported allergy to banana fruit. Positive by in vitro IgE test and by SPT (prick to prick with fruit of banana). 11 of 11 positive by SPT using natural fruit. 10 of 11 positive by IgE to natural protein in reducing immunoblot. 7 of 11 positive to recombinant protein (E. coli) in reducing immunoblot | 1 | 2015-08-26 12:00:00 | 2019-08-30 01:41:49 | ||
| Animalia Arthropoda | Hymenoptera | Myrmecia pilosula | Australian jumper ant | 451 | Myr p 1 | Pilosulin-1, M-myrmeciitoxin-Mp1 | 7.5 kDa and 5.5 kDa | - Of 44 sensitized patients, 52% showed IgE binding to a crude cell lysate of Myr p 1 clone lambda Mp34 in RAST. Recognition of 7.5 kD and 5.5 kD polypeptides on immunoblot. | 7678752 | 4 | 2003-05-31 12:00:00 | 2024-11-11 17:47:55 | |
| Animalia Arthropoda | Hymenoptera | Myrmecia pilosula | Australian jumper ant | 452 | Myr p 2 | Pilosulin-3, M-myrmeciitoxin-Mp2 | 8.5 kDa and 2-4 kDa | rMyr p 2 was recognized by IgE from jumper ant venom-allergic patients, both in RIA and on immunoblot. Of 57 subjects, 35% showed IgE binding to the expression product of the Myr p 2 clone lambdaMp37 in RIA. | 8605256 | 4 | 2003-05-31 12:00:00 | 2024-11-11 17:52:35 | |
| Animalia Arthropoda | Hymenoptera | Myrmecia pilosula | Australian jumper ant | 453 | Myr p 3 | pilosulin-4.1 | 8.2 kDa | 9 of 54 (16.7%) Australian Jumper ant venom allergic patients recognized Myr p 3 on immunoblot. | 17362256 | 4 | 2007-02-08 12:00:00 | 2019-09-04 23:09:49 | |
| Animalia Mollusca | Octopoda | Octopus vulgaris | Common octopus | 1167 | Oct v 1 | Tropomyosin | 37 kDa | Sera from 11 patients allergic to octopus (symptoms + positive SPT) were tested by IgE immunoblot. All sera had IgE to nOct v 1 in octopus extract and purified rOct v 1.0101 (expressed in E. coli). The IgE-binding band in the extract was identified as tropomyosin by a specific antibody. | 1 | 2025-09-02 15:29:21 | 2025-09-02 15:29:21 | ||
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 454 | Ole e 1 | Common olive group 1 | 16 kDa | 9 out of 10 serum samples from olive-allergic patients showed IgE binding to both natural Ole e 1 and rOle e 1 on immunoblot. | 9314349 | 2 | 2003-04-02 12:00:00 | 2019-09-04 23:10:41 | |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 456 | Ole e 2 | Profilin-1 | 15 kDa | 5 out of 10 olive pollen-allergic patients showed serum IgE binding to purified Ole e 2 on immunoblot, and 6 patients to rOle e 2. | 9314349 | 2 | 2003-04-03 12:00:00 | 2019-09-04 23:12:05 | |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 457 | Ole e 3 | Polcalcin | 9 kDa | Both native Ole e 3 and rOle e 3 bound IgE in a pool of sera of patients allergic to olive pollen, tested in immunoblot and ELISA | 9874211 | 2 | 2003-04-03 12:00:00 | 2019-09-04 23:12:33 | |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 458 | Ole e 4 | 32 kDa | Ole e IV | 16 out of 20 sera from patients with positive skin test to olive pollen extract (80%), showed IgE binding to Ole e 4 in immunoblot. IgE binding to olive pollen extract in ELISA could be inhibited by Ole e 4 up to 75%. | 9500754 | 2 | 2003-04-03 12:00:00 | 2019-09-04 23:13:28 | |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 459 | Ole e 5 | Superoxide dismutase [Cu-Zn] | 16 kDa | 7 out of 20 sera from patients with positive skin test to olive pollen extract (35%), showed IgE binding to Ole e 5 in immunoblot. IgE binding to olive pollen extract in ELISA can be inhibited by Ole e 5 up to 40%. | 9500754 | 2 | 2003-04-03 12:00:00 | 2019-09-04 23:13:55 | |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 460 | Ole e 6 | 10 kDa | In immunoblotting analysis with 255 sera from patients allergic to olive pollen, 40 sera (15%) showed IgE binding to purified Ole e 6. Prevalence was strongly dependent upon geographical area. | 9237648 | 2 | 2003-02-03 12:00:00 | 2024-06-28 17:48:21 | ||
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 461 | Ole e 7 | putative non-specific lipid transfer protein | 9.5 kDa | Ole e VII | Of 164 sera from patients allergic to olive, 77 sera showed IgE binding to purified Ole e 7 in ELISA (47%). | 10518824 | 2 | 2003-04-02 12:00:00 | 2019-05-04 18:28:56 |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 462 | Ole e 8 | Polcalcin-like protein (4 EF-hands) | 21 kDa | PCA18/PCA23 | Recombinant protein binds IgE antibodies from patients allergic to olive pollen | 10648840 | 2 | 2003-04-07 12:00:00 | 2019-09-04 23:15:12 |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 463 | Ole e 9 | Beta-1-3 glucanase | 46 kDa | In ELISA with purified Ole e 9, 65% of 46 sera of patients that were allergic to olive showed IgE binding to Ole e 9 allergen. | 11373288 | 2 | 2004-04-25 12:00:00 | 2025-08-25 19:12:10 | |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 455 | Ole e 10 | X8 domain containing protein | 10.8 kDa | Ole e 10 displays 55% prevalence among 150 olive pollen-allergic patients and 69.2% among 13 patients sensitized exclusively to Olea pollen tested by ELISA. | 15004167 | 2 | 2006-11-05 12:00:00 | 2019-09-04 23:29:02 | |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 685 | Ole e 11 | Pectin methylesterase | 37.4 kDa | Patients allergic to olive pollen from geographical areas with high levels of olive pollen grains in the air (Jaen, Spain n= 104; Cordoba, Spain n= 41) had prevalence values of 63.5% to rOle e 11 (n= 66) and 75.6% (n= 31), respectively. A population from Madrid, Spain (n= 34, with CAP>4) exposed to moderate levels of olive pollen had a prevalence value of 55.9% to rOle e 11 (n= 19). | 20491902 | 2 | 2010-05-27 12:00:00 | 2019-09-04 23:52:43 | |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 922 | Ole e 12 | Isoflavone reductase | 37 kDa | Twenty two patients out of 63 recruited with peach allergy also had olive pollen sensitization. These were tested for IgE binding to recombinant E. coli produced protein by ELISA. Earlier work had shown IgE binding to this protein from a different subject as early as 2008. Natural protein was also purified and proteomics demonstrated it was the same protein and had IgE binding in 2D gel blots. | 26391288 | 2 | 2018-04-04 18:32:54 | 2019-09-04 23:35:48 | |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 923 | Ole e 13 | Thaumatin-like protein | 23 kDa | Occupational inhalation allergy for one subject in olive pressing operation from fruit. SPT +, In vivo challenge positive. Also 63 of 482 subjects with IgE binding out of 482. | 18354115 | 2 | 2018-04-04 19:01:09 | 2023-07-17 16:15:58 | |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 911 | Ole e 14 | Polygalacturonase | 46.5 kDa | 63 of 482 pollen allergic subjects had IgE binding to rOle e 14. Although most were higher in IgE binding to the homologous Sal k 6 from Salsola kali. | 30173224 | 2 | 2017-12-14 23:30:07 | 2020-05-08 18:37:09 | |
| Plantae Eudikotyledons | Lamiales | Olea europaea | Olive | 921 | Ole e 15 | Cyclophilin, peptidyl prolyl cis-trans isomerase | 19 kDa | Patients allergic to olive pollen (Cordoba Spain, 27% positive), or to olive pollen and grass pollen (Madrid, Spain, 16% positive by ELISA), were tested for IgE binding to recombinant E. coli produced olive cyclophilin. Total of 79 patients tested, 17 were positive, 5 negative controls. | 31192604 | 2 | 2018-03-20 17:54:35 | 2025-08-25 19:03:46 | |
| Animalia Chordata | Salmoniformes | Oncorhynchus keta | Chum salmon | 764 | Onc k 5 | beta-prime-component of vitellogenin | 18 kDa | 20/20 chum salmon roe allergic patients had IgE that reacted with natural Onc k 5 in immunoblots of chum salmon roe extracts. Purified natural Onc k 5 bound IgE from sera of 6/6 chum salmon roe allergic patients in ELISA. | 19226142 | 1 | 2012-12-18 12:00:00 | 2020-05-14 23:52:15 | |
| Animalia Chordata | Salmoniformes | Oncorhynchus mykiss | Rainbow trout | 727 | Onc m 1 | Beta-parvalbumin | 12 kDa | Fifty fish allergic subjects serum IgE were tested for binding to proteins from Kokane and salmon and mackerel as well as tuna were tested, including Rainbow trout, by ELISA and immunoblots. ELISA values show good correlation between fish, Immunoblot with six subjects allergic to salmon and two sera with high ImmunoCAPs showed strong IgE binding for 4 of eight and weak in two, to 13 kDa band and also a 50 kDa band and 25 kDa. Inhibition with kokanee and red salmon to both showed equal dose/inhibition. From ELISA inhibition of a pool of six sera, rainbow trout and mackerel were able to inhibit binding to kokanee and red salmon within 0.5 log dilution of Red salmon and kokanee, whereas silver salmon was 1 log lower and tuna was < 2 logs lower inhibiting binding. | 19390241 | 1 | 2011-04-14 12:00:00 | 2019-09-05 00:08:03 | |
| Animalia Chordata | Cichliformes | Oreochromis mossambicus | Mozambique tilapia | 747 | Ore m 4 | Tropomyosin | 33 kDa | 10 patients were selected on the basis of a convincing clinical history of tilapia allergy as well as a positive skin prick test and a positive double-blind placebo-controlled food challenge to tilapia. Sera of all 10 patients had IgE that reacted with purified natural Ore m 4 in Westernblots. | 23414545 | 1 | 2012-07-30 12:00:00 | 2019-09-05 00:30:47 | |
| Animalia Chordata | Lagomorpha | Oryctolagus cuniculus | Rabbit | 464 | Ory c 1 | Lipocalin | 17-18 kDa | AgR1 | All 14 sera of patients sensitive to rabbits showed IgE binding to Ory c 1 in XRIE. | 3344934 | 2 | 2003-02-11 12:00:00 | 2019-09-05 00:35:20 |
| Animalia Chordata | Lagomorpha | Oryctolagus cuniculus | Rabbit | 1096 | Ory c 2 | Odorant binding protein 2; member of the lipocalin family | 18 kDa (SDS-PAGE, non-red.), 22 kDa (SDS-PAGE red.), 16,351 Da (MALDI-MS) | Sera from 28 patients allergic to rabbit (symptoms, SPT, sIgE) were tested by ELISA with purified natural and recombinant Ory c 2. Of those, 20 and 21 (71% and 75%) had IgE to the natural and recombinant allergen, respectively, with a high correlation (r = 0.98) between both values. nOry c 2 activated basophils from all 3 tested patients. | 35991307 | 2 | 2022-04-26 12:17:01 | 2024-10-09 16:23:14 | |
| Animalia Chordata | Lagomorpha | Oryctolagus cuniculus | Rabbit | 767 | Ory c 3 | Lipophilin | 19-21 kDa (glycosylated heterodimer), 12-14 kDa (deglycosylated heterodimer) | Ory c 2 | The purified natural Ory c 3 bound IgE from 27/35 rabbit allergic individuals in ELISA. 5/5 tested patients reacted positive with purified natural Ory c 3 in SPT. | 23763973 | 2 | 2013-01-24 12:00:00 | 2025-08-26 14:45:15 |
| Animalia Chordata | Lagomorpha | Oryctolagus cuniculus | Rabbit | 782 | Ory c 4 | Lipocalin | 24 kDa | IgE binding to 46% of 35 subjects with possible allergy to rabbit. Tested by recombinant Ory c 4 by ELISA, along with IgE to nOry c 3 adn rFel d 1, r Fel d 4, rCan f 6, nrabbit extract, nFel d 2 adn nCan f 3. Update 29 Jan 2018 with publication and new address. | 24369806 | 2 | 2013-10-08 12:00:00 | 2019-09-05 00:44:21 | |
| Plantae Liliopsida (monocots) | Poales | Oryza sativa | Rice | 465 | Ory s 1 | Beta-expansin | 35 kDa | IgE Ab from pooled sera of patients with high sensitivity for rye-grass pollen bound 35 kD protein in immunoblot of rice pollen extract, which binding could completely be inhibited by rOry s 1. | 7590339 | 2 | 2003-02-17 12:00:00 | 2019-09-05 00:45:33 | |
| Plantae Liliopsida (monocots) | Poales | Oryza sativa | Rice | 466 | Ory s 12 | Profilin A | 14 kDa | IgE binding was tested to extracts and recombinant proteins from Hirano et al., 2013, J Biochem. The 10 subjects sera from Japan were tested positive to beta expansin and polycalcin extensin and weakly to polygalacturonase, almost negative to profilin. The clones were expressed as fusion proteins with thioredoxin and the three subjects with IgE binding to fused recombinant protein were nearly all due to thioredoxin. Those without IgE to thioredoxin did not bind. The significance of the three binding to fused thioredoxin and profilin is therefore not clear. | 23694780 | 2 | 2003-03-25 12:00:00 | 2019-09-05 00:46:55 | |
| Plantae Eudikotyledons | Fagales | Ostrya carpinifolia | European hop-hornbeam | 697 | Ost c 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 17 kDa | 2 | 2013-06-04 12:00:00 | 2019-09-05 00:52:57 | |||
| Animalia Arthropoda | Hymenoptera | Pachycondyla chinensis | Asian needle ant | 851 | Pac c 3 | Antigen 5 | 23 kDa | 5 out of 6 patients sera tested positive for IgE binding using recombinant protein | 19178543, 27043037 | 4 | 2015-11-02 12:00:00 | 2020-03-23 19:15:14 | |
| Plantae Eudikotyledons | Apiales | Panax ginseng | Korean ginseng | 1151 | Pana g 1 | Pathogenesis-related protein PR-10-1, Bet v 1-related protein, ribonuclease 1 | 17 kDa | Sera from 5 Korean patients with tree pollen allergy, who reported oral allergic symptoms after eating raw ginseng, were tested. Of those, 4 had IgE to recombinant Pana g 1.0101 as measured by ELISA | 1 | 2024-06-20 15:14:16 | 2024-09-17 18:38:14 | ||
| Animalia Arthropoda | Decapoda | Pandalus borealis | Northern shrimp | 712 | Pan b 1 | Tropomyosin | 37 kDa | 7 of 8 shrimp allergic individuals reacted positive in a skin prick test with purified Pan b 1. 4 of 6 individuals showed a positive basophil activation test with Pan b 1. 5 of 5 individuals tested positive in an IgE immunoblot with Pan b 1. 4 of 4 individuals tested positive in an IgE ELISA with Pan b 1. | 23075760 | 1 | 2011-03-22 12:00:00 | 2019-09-05 00:59:04 | |
| Animalia Chordata | Siluriformes | Pangasianodon hypophthalmus | Striped catfish | 961 | Pan h 1 | Parvalbumin beta | 11 kDa | 8 of 80 subjects with clinically confirmed fish allergy reported immediate reactions to ingestion of this catfish. 61 of those subjects had positive SPT to catfish. 29 of 80 subjects were positive by IgE binding to the purified Pan h 1.0101, beta parvalbumin, which matches the genomic sequences. 10 subjects were positive to purified Pan h 1.0201. | 32860256 | 1 | 2019-05-30 18:25:21 | 2021-01-11 16:51:17 | |
| Animalia Chordata | Siluriformes | Pangasianodon hypophthalmus | Striped catfish | 978 | Pan h 2 | beta-enolase | 50 kDa | 80 subjects with food allergy to striped catfish, Pangasianodon hypophthalmus, were tested by SPT with muscle of this species in saline buffer and 61 were found to have > 5 mm weal. IgE binding to proteins were tested by SDS-PAGE reducing blots and the protein at the identified band was identified by LC-MSMS with 89% coverage compared to genomic predicted protein by quantitative assessment. 18 subjects had positive binding. 10 controls were negative and the other 62 of the fish allergic subjects were negative. | 32860256 | 1 | 2019-09-12 00:24:59 | 2021-01-11 16:51:40 | |
| Animalia Chordata | Siluriformes | Pangasianodon hypophthalmus | Striped catfish | 979 | Pan h 3 | Aldolase A | 40 kDa | Clinical data: A total of 80 fish-allergic patients were included in this study. All had a convincing history of IgE-mediated fish allergy and a sensitization to at least one fish species confirmed by skin prick test with commercial and in-house fish preparations. Eight patients reported typical IgE-mediated allergic reactions after ingestion of Pangasianodon hypophthalmus. As negative controls, 2 non-atopic individuals without history of type I allergy and 8 individuals with allergy to shellfish were used.Among those 10 individuals, only one individual with shellfish allergy demonstrated IgE reactivity to this aldolase A. | 32860256 | 1 | 2019-09-21 20:02:57 | 2021-06-18 16:16:29 | |
| Animalia Chordata | Siluriformes | Pangasianodon hypophthalmus | Striped catfish | 980 | Pan h 4 | Tropomyosin alpha | 35 kDa | Clinical data: A total of 80 fish-allergic patients were included in this study. All had a convincing history of IgE-mediated fish allergy and a sensitization to at least one fish species confirmed by skin prick test with commercial and in-house fish preparations. Eight patients reported typical IgE-mediated allergic reactions after ingestion of Pangasianodon hypophthalmus. As negative controls, 2 non-atopic individuals without history of type I allergy and 8 individuals with allergy to shellfish were used. Among those 10 individuals, only three individuals with shellfish allergy demonstrated IgE reactivity to this tropomyosin. IgE binding was positive in 27 of 80 subjects, and SPT in 61 of 80. | 32860256 | 1 | 2019-09-21 20:34:31 | 2021-01-11 16:52:17 | |
| Animalia Chordata | Siluriformes | Pangasianodon hypophthalmus | Striped catfish | 981 | Pan h 7 | Creatine kinase | 43 KDa | Seven of 80 fish allergic subjects with SPT+ wheal to Striped catfish had IgE binding to creatin kinase, with high sequence identity to the predicted protein of genomic sequence of this gene. | 32860256 | 1 | 2019-09-21 23:37:15 | 2021-06-18 16:17:19 | |
| Animalia Chordata | Siluriformes | Pangasianodon hypophthalmus | Striped catfish | 982 | Pan h 8 | Triosephosphate isomerase | 25 kDa | 17 subjects of 80 with history of allergy to Striped catfish had IgE binding to the protein identified by LC-MSMS, matching the predicted protein from the gene of the species. and 61 of the 80 were SPT+ to muscle of the species | 32860256 | 1 | 2019-09-21 23:55:33 | 2021-01-11 16:53:06 | |
| Animalia Chordata | Siluriformes | Pangasianodon hypophthalmus | Striped catfish | 983 | Pan h 9 | Pyruvate kinase PKM-like | 65 kDa | six subjects had IgE binding to the protein of the 80 allergic to Striped catfish, with 61 being SPT+ to meat of the fish. The sequence was determined by LC-MSMS, matched to the predicted protein of the genome. | 32860256 | 1 | 2019-09-22 00:13:29 | 2021-01-11 16:53:25 | |
| Animalia Chordata | Siluriformes | Pangasianodon hypophthalmus | Striped catfish | 984 | Pan h 10 | L-lactate dehydrogenase | 34 kDa | 12 subjects allergic to striped catfish of the 80 tested allergic subjects had IgE binding to this protein, which had sequence identified by LC-MSMS. 61 of teh 80 had SPT+ to muscle of the fish. | 32860256 | 1 | 2019-09-22 18:41:48 | 2021-01-11 16:53:45 | |
| Animalia Chordata | Siluriformes | Pangasianodon hypophthalmus | Striped catfish | 985 | Pan h 11 | Glucose 6-phosphate isomerase | 60 kDa | Five subjects had IgE binding to protein out of 80 subjects with allergy to striped catfish. 61 subjects were SPT+ to muscle of the striped catfish | 32860256 | 1 | 2019-09-22 19:12:33 | 2021-01-11 17:00:11 | |
| Animalia Chordata | Siluriformes | Pangasianodon hypophthalmus | Striped catfish | 988 | Pan h 13 | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) | 36 kDa | Six of 80 SPT challenged to raw extracts of this fish species were called allergic subjects and the six had IgE binding to this purified native protein. SPT with fish extract was judge positive when >5 mm diameter | 32860256 | 1 | 2019-11-03 21:37:20 | 2025-08-25 19:14:13 | |
| Animalia Arthropoda | Decapoda | Panulirus stimpsoni | Spiny lobster | 467 | Pan s 1 | Tropomyosin | 34 kDa | Sera from subjects with crustacean allergies, when preabsorbed with recombinant protein Pan s I, lost their IgE reactivity to muscle extract of P. stimpsoni. | 9597774 | 1 | 2003-10-27 12:00:00 | 2019-09-05 01:01:28 | |
| Plantae basal Mesangiosperms | Ranunculales | Papaver somniferum | Opium poppy | 1128 | Pap s 1 | Vicilin (7S globulin) with N-terminal alpha-hairpinin peptides | 10 kDa, 17 kDa (alpha-hairpinins), 50 kDa (vicilin) | Pap s 1 is post-traslationally cleaved into N-terminal alpha-hairpinin peptides and the C-terminal mature vicilin. Both parts were separately purified and tested for IgE binding. Therefore, see the isoallergen records for IgE binding data. | 38734371 | 1 | 2023-08-29 15:16:01 | 2024-05-23 13:17:40 | |
| Plantae basal Mesangiosperms | Ranunculales | Papaver somniferum | Opium poppy | 1129 | Pap s 2 | Legumin (11S globulin) seed storage protein | 52 kDa (non-reducing), 30 kDa + 20 kDa (reducing) | Of 36 tested poppy seed-sensitized patients (SPT, sIgE), 10 had allergic symptoms after oral food challenge. Of those, 10 allergic (100%) and 21 tolerant (81%) had IgE to natural Pap s 2 as shown by ELISA. As only the natural allergen was tested, which is a mixture of Pap s 2.0101 and Pap s 2.0201 (as shown by tandem MS), the contributions of the individual isoallergens to IgE binding was not determined. | 38734371 | 1 | 2023-08-29 16:19:20 | 2024-05-23 13:18:41 | |
| Plantae basal Mesangiosperms | Ranunculales | Papaver somniferum | Opium poppy | 1130 | Pap s 3 | Late embryogenesis abundant protein 5 (LEA-5); small hydrophilic seed protein | 10 kDa | Of 36 tested poppy seed-sensitized patients (SPT, sIgE), 10 had allergic symptoms after oral food challenge. Of those, 8 allergic (80%) and 17 tolerant (65%) had IgE to natural Pap s 3 as shown by ELISA. As only the natural allergen was tested, which is a mixture of Pap s 3.0101 and Pap s 3.0201 (as shown by tandem MS), the contributions of the individual isoallergens to IgE binding was not determined. | 38734371 | 1 | 2023-08-29 17:47:02 | 2024-05-23 13:19:47 | |
| Animalia Arthropoda | Decapoda | Paralithodes camtschaticus | Red king crab | 1150 | Para c 11 | Mitochondrial malate dehydrogenase | 39 kDa | 99 sera from shellfish-allergic patients, as diagnosed by convincing history of allergic reactions after shellfish ingestion, positive SPT with shellfish extract mix and crab ImmunoCAP > 0.7 kUA/L, were tested. Of those, 7 sera (7%) had IgE to recombinant Para c 11.0101 as measured by ELISA. | 40736448 | 1 | 2024-05-17 17:51:27 | 2025-10-21 13:10:53 | |
| Plantae Eudikotyledons | Rosales | Parietaria judaica | Pellitory of the wall | 468 | Par j 1 | Non-specific lipid transfer protein type 1 (nsLTP1) | 15 kDa | Recombinant Par j 1 bound to IgE in 95% of the sera from Pj-allergic patients (n = 22)tested. rPar j 1 was capable of inducing histamine release from basophils of subjects allergic to Pj pollen (n=6), and Par j 1 was capable of inhibiting 40% of IgE binding to allergens in crude Pj pollen extract. | 9104791 8137937 | 2 | 2003-04-22 12:00:00 | 2025-04-10 18:20:53 | |
| Plantae Eudikotyledons | Rosales | Parietaria judaica | Pellitory of the wall | 469 | Par j 2 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10-14 kDa | rPar j 2.0101 reacted with IgE of 82% (23/28) of the sera of Pj-allergic subjects analyzed. - The majority (83%) of the 36 Mediterranean weed pollen-allergic patients tested (with high Parietaria pollen exposure) mounted high IgE antibody levels (mean specific IgE, 20.89 kUA/L) against recombinant Par j 2. | 8985165 | 2 | 2003-04-22 12:00:00 | 2025-04-10 18:21:06 | |
| Plantae Eudikotyledons | Rosales | Parietaria judaica | Pellitory of the wall | 470 | Par j 3 | Profilin | 14 kDa | 28 selected patients had positive Skin prick tests ( > 4 mm of wheal diameter) to Pj profilin and serum Pj-specific IgE (CAP-System, Pharmacia, Uppsala, Sweden). | 11958736 | 2 | 2003-04-22 12:00:00 | 2020-05-13 21:57:53 | |
| Plantae Eudikotyledons | Rosales | Parietaria judaica | Pellitory of the wall | 471 | Par j 4 | Polcalcin | 9 kDa | IgE prevalence: 6% of 33 patients tested in immunoblot; 100% of 10 patients with an allergy to calcium binding proteins. | 2 | 2007-12-21 12:00:00 | 2019-09-05 01:16:15 | ||
| Plantae Eudikotyledons | Rosales | Parietaria officinalis | Pellitory | 472 | Par o 1 | Non-specific lipid transfer protein type 1 (nsLTP1) | 15 kDa | All 29 Parietaria-allergic patients tested were skin test positive to Par o I and possessed high levels of specific serum IgE antibody, as determined by radioallergosorbent test (RAST). | 1752693 | 2 | 2003-04-22 12:00:00 | 2025-04-10 18:21:24 | |
| Plantae Eudikotyledons | Asterales | Parthenium hysterophorus | Santa Maria feverfew | 877 | Par h 1 | Defensin-like protein linked to polyproline-rich region, Art v 1 homologue | 12 kDa | Subjects with weed pollen allergy from Austria, Canada and Korea. In vitro IgE tested with recombinant protein that was cloned based on the work of Gupta 1996. 21 of 40 Austrians +, 16 of 38 Canadians +, 9 of 27 Korean subjects +. Also 4 of 7 were postive in hRBL assay. All used recombinant protein. Previous results from Gupta for IgE binding and protein, with N-terminal determination | 8939153,28729676 | 2 | 2016-06-26 12:00:00 | 2024-09-16 18:38:33 | |
| Plantae Liliopsida (monocots) | Poales | Paspalum notatum | Bahia grass | 473 | Pas n 1 | Beta-expansin | 29 kDa | 100% of 19 grass pollen-allergic patients reacted to natural Pas n 1 (Western blot). 85% of 55 Bahia grass pollen allergic patients reacted to recombinant Pas n 1 (ELISA) | 18817975 | 2 | 2008-01-28 12:00:00 | 2020-05-14 18:07:26 | |
| Animalia Arthropoda | Decapoda | Penaeus aztecus | Brown shrimp | 474 | Pen a 1 | Tropomyosin | 36 kDa | A 36-kDa allergen, demonstrated in both extracts by SDS-PAGE/Western blot analysis, reacted with 28/34 (82%) sera from shrimp-sensitive, skin test and RAST-positive, individuals. IgE-reactive Pen a 1 peptides: medline 97276841 | 7916224 | 1 | 2003-10-27 12:00:00 | 2019-09-05 01:26:15 | |
| Animalia Arthropoda | Decapoda | Penaeus indicus | Shrimp | 489 | Pen i 1 | Tropomyosin | 34 kDa | IgE binding to Pen i 1 in ELISA. IgE binding to tryptic peptides of Pen i 1 in ELISA and dot-blot immunoassay. | 7693809 | 1 | 2003-10-30 12:00:00 | 2019-09-05 01:55:43 | |
| Animalia Arthropoda | Decapoda | Penaeus monodon | Black tiger shrimp | 490 | Pen m 1 | tropomyosin | 38 kDa | 11 of 16 shrimp-allergic patients had IgE that reacted with natural Pen m 1 in immunoblot. | 24420734 | 1 | 2006-10-13 12:00:00 | 2019-09-05 02:01:55 | |
| Animalia Arthropoda | Decapoda | Penaeus monodon | Black tiger shrimp | 491 | Pen m 2 | arginine kinase | 40 kDa | 27% (5 of 18) of shrimp allergic sera showed significant IgE binding to Pen m 2 from the crude P. monodon extract on immunoblot. | 12496430 | 1 | 2006-10-13 12:00:00 | 2019-09-05 21:33:25 | |
| Animalia Arthropoda | Decapoda | Penaeus monodon | Black tiger shrimp | 692 | Pen m 3 | Myosin light chain 2 | 20 kDa | 1 | 2010-09-14 12:00:00 | 2019-09-05 21:39:54 | |||
| Animalia Arthropoda | Decapoda | Penaeus monodon | Black tiger shrimp | 688 | Pen m 4 | Sarcoplasmic calcium binding protein | 20 kDa | 8 of 16 (50%) crustacean-allergic sera reacted to purified Pen m 4 by fluorescence ELISA. | 18204275 | 1 | 2010-06-16 12:00:00 | 2019-09-05 21:47:08 | |
| Animalia Arthropoda | Decapoda | Penaeus monodon | Black tiger shrimp | 694 | Pen m 6 | Troponin C | 16.8 kDa | 8 of 35 shrimp allergic individuals had IgE that reacted in immunoblot and ELISA with recombinant Pen m 6.0101 produced in E. coli (pET32a). | 10.1007/s00217-014-2349-y | 1 | 2010-09-14 12:00:00 | 2023-04-04 14:49:46 | |
| Animalia Arthropoda | Decapoda | Penaeus monodon | Black tiger shrimp | 1072 | Pen m 7 | Hemocyanin | 76 kDa | Seven of 32 subjects with apparent food allergy to shrimp had IgE binding by ELISA to recombinant protein expressed in bacculovirus | 1 | 2021-08-27 22:38:46 | 2021-08-30 16:09:15 | ||
| Animalia Arthropoda | Decapoda | Penaeus monodon | Black tiger shrimp | 1041 | Pen m 8 | Triosephosphate isomerase | 27 kDa | 12 of 30 subjects with histories of allergy to consumption of shrimp (P. monodon) by mouth itch, rashes, urticaria or anaphylaxis with adult and paediatric subjects, were positive in IgE binding using ELISA to recombinant protein. Two of the 12 were positive in a basophil activation test with Buhlmann flow CAST | 35567339 | 1 | 2020-12-02 18:57:15 | 2023-04-04 14:40:51 | |
| Animalia Arthropoda | Decapoda | Penaeus monodon | Black tiger shrimp | 1042 | Pen m 13 | Cytoplasmic fatty acid binding protein | 20 kDa | Twenty of 30 adult and paediatric subjects with reported clinical history of oral allergy to consumption of shrimp (P. monodon) were positive in DBPCFC, and positive in IgE binding by ELISA. Seven of 12 were positive to Buhlmann flow CAST to recombinant protein | 35567339 | 1 | 2020-12-02 19:10:44 | 2023-04-04 14:30:36 | |
| Animalia Arthropoda | Decapoda | Penaeus monodon | Black tiger shrimp | 1084 | Pen m 14 | Glycogen phosphorylase-like protein | 95 kDa | Eight of 17 people allergic to shrimp had IgE positivity by ELISA and 3 of 17 were positive by basophil activation (Buhlmann flow cast). A total of 20 people were tested and 3 negative by ELISA. Four people tested for BHA were negative. Subjects were tested by SPT with extract. Subjects were positive to ingestion of food. | 35567339 | 1 | 2022-02-04 19:40:34 | 2023-04-03 18:59:05 | |
| Fungi Ascomycota | Eurotiales | Penicillium brevicompactum | 475 | Pen b 13 | Alkaline serine protease | 33 kDa | Of 67 asthmatic patients, 11 showed serum IgE reactivity towards P.brevicompactum on immunoblot. 10 (91%)of these patients showed IgE binding to the 33 kD Pen b 13 on immunoblot. | 8732242 | 2 | 2003-08-26 12:00:00 | 2019-09-05 01:27:14 | ||
| Fungi Ascomycota | Eurotiales | Penicillium brevicompactum | 476 | Pen b 26 | Acidic ribosomal prot. P1 | 11 kDa | 16088208 | 2 | 2006-02-26 12:00:00 | 2020-05-14 17:55:26 | |||
| Fungi Ascomycota | Eurotiales | Penicillium chrysogenum | 484 | Pen ch 13 | Alkaline serine protease | 34 kDa | Among 70 sera from asthmatics patients, 17 had IgE reactivity towards P.chrysogenum on immunoblot. 15 patient sera (88%) showed IgE binding to 34 kD Pen ch 13 (identified by N-terminal sequence analysis) on immunoblot. - Basophils from 5 patients with a positive immunoblot for Pen ch 13, showed histamine release in response to Pen ch 13: medline 21890913 | 10231324 | 2 | 2003-08-26 12:00:00 | 2019-09-05 01:44:43 | ||
| Fungi Ascomycota | Eurotiales | Penicillium chrysogenum | 485 | Pen ch 18 | Vacuolar serine protease | 32 kDa | Among 17 P.chrysogenum-sensitized patients, 14 (82%) showed IgE binding to Pen ch 18 (identified by N-terminal sequence analysis) on immunoblot. - IgE epitope analysis: medline 21961432 (peptide C12, located in the N-terminal region of the molecule, was recognized by serum IgE in 75% of the patients tested) | 10231324 | 2 | 2003-08-26 12:00:00 | 2019-09-05 01:45:16 | ||
| Fungi Ascomycota | Eurotiales | Penicillium chrysogenum | 486 | Pen ch 20 | N-acetyl-glucosaminidase | 68 kDa | Sera of 7 asthmatic patients showed IgE binding to a 68 kD protein band on an immunoblot of P.chrysogenum extract. These patient sera also showed IgE binding to rPen ch 20 (lysate of clone A6) in a plaque immunoassay | 7600381 | 2 | 2003-08-31 12:00:00 | 2019-09-05 01:45:41 | ||
| Fungi Ascomycota | Eurotiales | Penicillium chrysogenum | 487 | Pen ch 31 | Calreticulin | 2 | 2007-02-08 12:00:00 | 2019-09-05 01:46:24 | |||||
| Fungi Ascomycota | Eurotiales | Penicillium chrysogenum | 488 | Pen ch 33 | 16 kDa | 2 | 2007-02-18 12:00:00 | 2019-09-05 01:47:21 | |||||
| Fungi Ascomycota | Eurotiales | Penicillium chrysogenum | 690 | Pen ch 35 | Transaldolase | 36.5 kDa | 2 | 2010-07-29 12:00:00 | 2019-09-05 01:48:07 | ||||
| Fungi Ascomycota | Eurotiales | Penicillium citrinum | 481 | Pen c 3 | Peroxysomal membrane protein | 18 kDa | Sera from 13 (46%) of the 28 Penicillium-sensitized asthmatic patients tested demonstrated IgE binding to Pen c 3 on immunoblot. | 10756236 | 2 | 2003-08-31 12:00:00 | 2019-09-05 01:29:43 | ||
| Fungi Ascomycota | Eurotiales | Penicillium citrinum | 477 | Pen c 13 | Alkaline serine protease | 33 kDa | IgE binding in ELISA | 11893850 9117886 | 2 | 2003-08-31 12:00:00 | 2020-05-14 17:56:13 | ||
| Fungi Ascomycota | Eurotiales | Penicillium citrinum | 478 | Pen c 19 | Heat shock protein P70 | 70 kDa | Sera from 14 (41%) of 34 Penicillium-allergic patients showed IgE-binding to the recombinant Pen c 19 in dot immunoassay, and to the 70 kDa component on an immunoblot of P. citrinum extract. | 9208190 | 2 | 2003-08-31 12:00:00 | 2019-09-05 01:30:02 | ||
| Fungi Ascomycota | Eurotiales | Penicillium citrinum | 479 | Pen c 22 | Enolase | 46 kDa | Sera from 7 (30%) of 23 Penicillium-sensitized asthmatic patients showed IgE binding to the 47-kD P. citrinum component (Pen c 22) and rPen c 22 on immunoblot. | 11979043 | 2 | 2003-08-31 12:00:00 | 2019-09-05 01:30:26 | ||
| Fungi Ascomycota | Eurotiales | Penicillium citrinum | 480 | Pen c 24 | elongation factor 1 beta | 25 kDa | Seven (8%) of the 92 serum samples from patients with bronchial asthma showed IgE-binding to the rPen c 24. Among these seven positive sera, five demonstrated IgE?binding to the C-terminal fragment (aa 119–228) while the other two sera showed IgE reactivity to the N-terminal fragment (aa 1–118) of pen c 24. | 15679724 | 2 | 2006-02-26 12:00:00 | 2019-09-05 01:38:34 | ||
| Fungi Ascomycota | Eurotiales | Penicillium citrinum | 482 | Pen c 30 | Catalase | 97 kDa | Serum IgE binding of ~ 48% of subjects with mold allergy and asthma in Taiwan study. At least part of the IgE binding was due to CCD (2 sites) on the protein. | 21136777 | 2 | 2007-02-08 12:00:00 | 2019-09-05 01:40:03 | ||
| Fungi Ascomycota | Eurotiales | Penicillium citrinum | 483 | Pen c 32 | Pectate lyase | 40 kDa | Three asthma, Penicillium sensitized subjects had IgE binding to recombinant Pen c 32.0101 in supplemental information PMID 21136777. | 21136777 | 2 | 2007-02-18 12:00:00 | 2019-09-05 01:42:14 | ||
| Fungi Ascomycota | Eurotiales | Penicillium crustosum | 737 | Pen cr 26 | 60S acidic ribosomal phosphoprotein P1 | 11 kDa | 14 of 61 (23%) atopic sera from Penicillium-sensitive individuals showed positive reactions for purified Pen cr 26 by immunoblot analysis. | 23902156 | 2 | 2014-02-18 12:00:00 | 2019-09-05 01:55:04 | ||
| Fungi Ascomycota | Eurotiales | Penicillium oxalicum | 492 | Pen o 18 | Vacuolar serine protease | 34 kDa | Among 70 asthmatic sera tested, 18 (26%) had IgE immunoblot reactivity towards components of P. oxalicum. Of these 18 sera, > 80% showed IgE-binding to a 34 kD protein, identified as a vacuolar serine proteinase by N-terminal sequence analysis. | 10231324 11174468 | 2 | 2003-08-31 12:00:00 | 2020-05-14 17:57:55 | ||
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 493 | Per a 1 | Nitrile-specifier, microvilli-like protein with unknown function | 45 kDa | Cr-PII | Of 35 allergic patients, 22 had a positive skin test to CR-extract and Per a 1. Of these 22 patients, 12 (54.4%) showed a positive skin reaction to rPer a 1. IgE Ab binding to rPer a 1 was demonstrated in ELISA. - Amino acid sequences 78LIRALFGL85 and 267IRSWFGLP1274 of the American cockroach Per a 1.0104 allergen were involved in IgE binding, as measured by ELISA. 80%-100% of the sera tested showed IgE binding to these peptides. | 10221434, 10329820 | 2 | 2003-05-16 12:00:00 | 2022-06-14 14:56:08 |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 798 | Per a 2 | Aspartic protease-like protein without proteolytic activity | 42 kDa | Twenty six of 41 subjects from Taiwan had positive serum IgE to recombinant Per a 2.0101 as measured by ELISA. Subjects had allergic rhinitis or asthma and rhinitis. All were positive >0.35 kU/L to cockroach by ImmunoCAP. | 22469443 | 2 | 2014-07-21 12:00:00 | 2025-10-02 10:22:50 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 495 | Per a 3 | Arylphorins/TO Arthropod hemocyanins | 72 kDa | Cr-PI | Of 23 cockroach-positive patients, 19 (82.6%) had positive immediate skin reactions in response to partially purified Per a 3 allergen. Of these 19 patients 9 (47.7%) had positive skin reactions to rPer a 3.01. All these 19 patients had IgE antibody against Per a 3, as measured by fluoroallergosorbent test | 8663281 | 2 | 2003-05-20 12:00:00 | 2019-09-05 22:03:07 |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 1058 | Per a 4 | Lipocalin-related calycin superfamily member | 17 kDa | Eighteen subjects out of 117 with reported histories of allergy to cockroach from multiple countries (India, Korea, Venezuela and Iran) were tested by western blots and positive reports were based on experimental ImmunoCAP to the recombinant protein. | 35386988 | 2 | 2021-04-30 04:53:18 | 2024-10-09 17:53:56 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 906 | Per a 5 | Glutathione S-transferase (GST) class delta | 23 kDa | Positive IgE tests with 15 of 15 cockroach allergic patients showing positive binding to natural and recombinant protein, with negative responses from 5 of 5. IgE binding tested by dot blot and ELISA. Subjects positive by SPT. NOTE:this submission was from Thailand in 2017, there was a previous paper by Wei et al., 2014 that showed IgE binding and basophil activity to a 98% identical sequence that Wei called Per a 5. That is now added as Per a 5.0102. | 29323160,24707117 | 2 | 2017-10-31 21:11:21 | 2026-01-29 15:51:39 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 496 | Per a 6 | Troponin C | 17 kDa | 2 | 2006-02-25 12:00:00 | 2019-09-05 22:07:46 | |||
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 497 | Per a 7 | Tropomyosin | 33 kDa | IgE-reacting Abs to the purified rPer a 7 were detected in immunoblots in 12 of 29 sera from CR-sensitive patients tested (41%). | 10201967 | 2 | 2003-05-20 12:00:00 | 2019-09-05 22:12:06 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 1059 | Per a 8 | Myosin light chain | 28 kDa non-reducing; 22 kDa reducing | 23 of 117 subjects with history of allergy to cockroach were positive in experimental ImmunoCAP to recombinant protein. In database of nucleotide by GQ Long and CL Zhang 2012. | 35386988 | 2 | 2021-04-30 05:21:43 | 2024-10-09 17:56:33 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 498 | Per a 9 | Arginine kinase | 43 kDa | 100% of 25 Thailand cockroach allergic subjects had IgE binding to rPer a 9; 80% of rhinitis patients in 20 Taiwanese cockroach allergic subjects had IgE to rPer a 9, 27% of those with Asthma and rhinitis to cockroach in Taiwan. | 16759988, 22469443 | 2 | 2007-02-08 12:00:00 | 2019-09-05 22:16:25 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 494 | Per a 10 | Serine protease | 28 kDa | 37 of 45 (82%) of patients hypersensitive to cockroach were positive in intradermal skin testing using the natural purified protein. | 18445191 | 2 | 2007-02-08 12:00:00 | 2019-09-05 22:16:51 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 833 | Per a 11 | alpha-amylase | 55 kDa | Sera from 39 of 40 (83%) patients reacted to Per a 11 on immunoblots. ELISA inhibition of serum IgE reactivity to the cockroach midgut extract (CME) using purified Per a 11 was significant (60%). Twelve of 15 (80%) cockroach-allergic patients had positive SPT reactions to Per a 11. In comparison with healthy control, Per a 11 at 1.0 g/ml induced approximately up to 5.8-fold increase in the number of CD63 and CCR3 double-positive cells following incubating it with PBMC from patients with cockroach allergy | 26361742 | 2 | 2015-06-02 12:00:00 | 2024-07-09 18:07:49 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 834 | Per a 12 | Chitinase | 45 kDa | Sera from 30 of 40 (63.8%) patients reacted to Per a 12 on immunoblots. ELISA inhibition of serum IgE reactivity to the cockroach midgut extract (CME) using purified Per a 12 was significant (40%). Nine of 15 (60%) cockroach-allergic patients had positive SPT reactions to Per a 12. In comparison with healthy control, Per a 12 at 1.0 g/ml induced approximately up to 5-fold increase in the number of CD63 and CCR3 double-positive cells following incubating it with PBMC from patients with cockroach allergy | 26361742 | 2 | 2015-06-02 12:00:00 | 2024-07-09 18:09:43 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 943 | Per a 13 | Glyceraldehyde-3-phosphate dehydrogenase | 36 kDa | GAPDH | Thirty subjects with history of allergy to cockroach were test positive by SPT with extract of the source (Periplaneta americana). 10 of the 30 had IgE binding to natural protein purified protein in immunoblots, and also by direct ELISA. Six of six were positive by in-direct basophil test. | 35033813 | 2 | 2018-10-12 00:25:11 | 2022-07-07 18:20:32 |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 1097 | Per a 14 | Enolase | 50 kDa | 14 of 20 subjects (70%) with asthma or rhinitis were IgE positive to recombinant protein. 10 non-allergic subjects were negative. Testing was by ELISA. | 36153808 | 2 | 2022-04-30 16:52:11 | 2023-04-03 14:34:54 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 1098 | Per a 15 | Cytochrome C | 15 kDa | Six of 20 subjects (30%) with asthma or rhinitis were IgE positive to recombinant cytochrome C by ELISA. 10 non-allergics were negative | 36153808 | 2 | 2022-04-30 17:05:02 | 2023-04-03 14:36:59 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 1099 | Per a 16 | Cofilin | 20 kDa | 16 of 20 subjects (80%) with asthma or rhinitis were IgE positive to recombinant protein by ELISA. 10 non-allergic subjects were negative | 36153808 | 2 | 2022-04-30 17:15:06 | 2023-04-03 14:38:39 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 1100 | Per a 17 | Alpha-tubulin | 53 kDa | 15 of 20 (75%) subjects with rhinitis or asthma and positive by SPT to extract of Periplaneta americana were IgE positive to recombinant alpha-tubulin in ELISA. 10 subjects without allergy were negative | 36153808 | 2 | 2022-04-30 17:25:36 | 2023-04-03 14:26:34 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 1101 | Per a 18 | Peptidyl-prolyl-cis-trans isomerase; Cyclophilin | 24 kDa | 16 of 20 subjects (80%) with asthma or rhinitis and SPT positive to extract of Periplaneta americana were IgE positive to recombinant protein by ELISA. Ten subjects without allergy were negative | 36153808 | 2 | 2022-04-30 17:36:37 | 2023-04-03 14:40:43 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 1102 | Per a 19 | Porin 3 | 7.4 kDa | 13 of 20 subjects with asthma or rhinitis and SPT positive to extract of Periplaneta americana had IgE binding to recombinant Porin3 in ELISA. 10 subjects without allergy were negative. | 36153808 | 2 | 2022-04-30 17:48:44 | 2023-04-03 14:45:13 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 1111 | Per a 20 | Peroxiredoxin-6 (Prx6) | 24 kDa | Twenty patients with allergic rhinitis to American cockroach (symptoms, SPT, IgE) were tested by ELISA for IgE to recombinant Per a 20.0101, produced in E. coli. Of those, 14 (70%) yielded OD-values that exceeded the mean + 2x SD of the results obtained with sera from 10 non-allergic donors. | 36153808 | 2 | 2022-06-14 15:06:18 | 2023-04-03 14:52:23 | |
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 1179 | Per a 21 | Fructose bisphosphate aldolase | 39 kDa (SDS-PAGE), 160 kDa (SEC; tetramer) | Sera from 77 cockroach-allergic patients were tested. Symptoms were rhinitis, asthma, urticaria or atopic dermatitis. Specific IgE was detected via ImmunoCAP i6 (German cockroach) and IgE-ELISA (American cockroach extract). Sera from 17 non-atopic donors served as negative controls. In an IgE-ELISA, 48 (62%) and 44 (57%) sera had IgE binding to nPer a 21 and rPer a 21.0101. In an indirect basophil activation test, cells sensitized with 5 pools of ELISA-positive sera were activated by rPer a 21.0101 at 10 µg/mL. | 2 | 2025-10-02 10:50:29 | 2025-10-02 10:50:29 | ||
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 1180 | Per a 22 | Pyruvate kinase | 58 kDa (SDS-PAGE), ~220 kDa (SEC, tetramer) | Sera from 77 cockroach-allergic patients were tested. Symptoms were rhinitis, asthma, urticaria or atopic dermatitis. Specific IgE was detected via ImmunoCAP i6 (German cockroach) and IgE-ELISA (American cockroach extract). Sera from 17 non-atopic donors served as negative controls. In an IgE-ELISA, 55 (71%) and 56 (73%) sera had IgE binding to nPer a 22 and rPer a 22.0101. In an indirect basophil activation test, cells sensitized with 5 pools of ELISA-positive sera were activated by rPer a 22.0101 at 10 µg/mL. | 2 | 2025-10-02 11:06:47 | 2025-10-02 11:06:47 | ||
| Animalia Arthropoda | Blattodea | Periplaneta americana | American cockroach | 1185 | Per a 23 | Glutathione S-transferase (GST) class sigma (related to Bla g 5) | 24 kDa | Sera from 68 cockroach-allergic patients (symptoms + SPT to P. americana extract) were tested by ELISA. Of those, 24 (35%) contained IgE to rPer a 23. Sera from five non-atopic donors did not bind to the allergen. | 41925067 | 2 | 2026-02-16 14:12:30 | 2026-04-16 12:49:58 | |
| Plantae basal Mesangiosperms | Laurales | Persea americana | Avocado | 499 | Pers a 1 | Class I chitinase | 32 kDa | Prs a 1 | Of 20 avocado and/or latex-allergic patients, 15 showed IgE binding to 32 kD Pers a 1 on immunoblot of avocado extract. rPers a 1 was recognized by IgE in serumpool of these patients. | 9774427 | 1 | 2003-07-03 12:00:00 | 2019-09-05 22:23:17 |
| Plantae Liliopsida (monocots) | Poales | Phalaris aquatica | Canary grass | 500 | Pha a 1 | Beta-expansin | 34 kDa | IgE binding in immunoblots of Pha a 1 was found to occur in 19/24 patient sera. | 7687099 | 2 | 2003-02-17 12:00:00 | 2019-09-05 22:23:57 | |
| Plantae Liliopsida (monocots) | Poales | Phalaris aquatica | Canary grass | 501 | Pha a 5 | 28.8-33.5 kDa | rPha a 5 binds to IgE in pooled sera of 4 grass pollen-allergic patients | 8564724 | 2 | 2003-02-17 12:00:00 | 2019-09-05 22:24:38 | ||
| Plantae Eudikotyledons | Fabales | Phaseolus vulgaris | Green bean, French bean | 502 | Pha v 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 8.8-9.0 kDa | 1 | 2009-09-04 12:00:00 | 2025-04-10 18:21:43 | |||
| Plantae Liliopsida (monocots) | Poales | Phleum pratense | Timothy | 503 | Phl p 1 | Beta-expansin | 27 kDa | 95% of grass pollen-allergic patients (98 tested) showed IgE binding to Phl p 1 in immunoblot of pollen extract; 97/98 subjects showed IgE binding to rPhl p 1 on nitrocellulose filters. | 1597349 | 2 | 2003-02-13 12:00:00 | 2019-09-05 22:42:50 | |
| Plantae Liliopsida (monocots) | Poales | Phleum pratense | Timothy | 507 | Phl p 2 | Grass group II/III | 10-12 kDa | Recombinant Phl p 2 on nitrocellulose disks was recognized by serum IgE of 65% of 98 grass pollen-allergic patients tested. Strong positive correlation between IgE-binding to recombinant or natural allergen and clinical symptoms/SPT and RAST. | 1597349 | 2 | 2003-02-17 12:00:00 | 2019-09-05 22:44:22 | |
| Plantae Liliopsida (monocots) | Poales | Phleum pratense | Timothy | 1013 | Phl p 3 | Group 3 grass pollen allergen; comtains a C-terminal expansin domain | 10.9 kDa | 70 grass pollen allergic subjects sera were tested from Germany, by western blot. 57% bound to Phl p 1, 2 and 3. They designated two proteins, 3.0101 and 3.0102, with 3 AA differences D20N, S88K, K94T. No glycosylation sites, no Cysteines. Accession AY421969 as 3.0101. Antibodies to Phl p 2 and Phl p 3 were somewhat cross-reactive. They are 57% identical. Basophil activity was shown similar for 3 patients for Phl p 2 and Phl p 3. | 16776686 | 2 | 2020-06-17 16:51:08 | 2022-04-29 16:12:08 | |
| Plantae Liliopsida (monocots) | Poales | Phleum pratense | Timothy | 508 | Phl p 4 | Berberine bridge enzyme | 55 kDa | 82% of patients tested showed IgE binding to 60 kd Phl p 4 proteins on immunoblot of ragweed pollen extract. IgE binding to nitrocellulose-blotted ragweed pollen extract was inhibited with purified Phl p 4 (2 patients tested) - 75% of grass pollen-allergic patients show IgE binding to Phl p 4 on immunoblot of timothy grass pollen extract. See also medline 96316935 | 1597349 | 2 | 2003-02-13 12:00:00 | 2019-09-05 22:45:03 | |
| Plantae Liliopsida (monocots) | Poales | Phleum pratense | Timothy | 509 | Phl p 5 | 32 kDa | 95% of grass pollen-allergic patients (98 tested) showed IgE binding to Phl p 5 in immunoblot of pollen extract; 97/98 subjects showed IgE binding to rPhl p 5 on nitrocellulose filters. - all patients (11) with positive skin prick test responses to grass pollen allergens reacted to the C-terminal, and 73% react to the N-terminal peptide of Phl p 5a. - Purified rPhl p 5 elicited dose-dependent basophil histamine release in 1 patient tested, and immediate type skin reactions in 4 patients test | 1597349 | 2 | 2003-02-13 12:00:00 | 2019-09-05 22:45:36 | ||
| Plantae Liliopsida (monocots) | Poales | Phleum pratense | Timothy | 510 | Phl p 6 | 11 kDa | rec.Phl p 6 reacted with serum IgE from 75% of grass pollen-allergic patients (n = 171). - Purified rPhl p 6 elicited dose-dependent basophil histamine release in 1 patient tested, and immediate type skin reactions in 4 patients tested. | 10553075 | 2 | 2003-02-17 12:00:00 | 2019-09-05 22:48:55 | ||
| Plantae Liliopsida (monocots) | Poales | Phleum pratense | Timothy | 511 | Phl p 7 | Polcalcin | 6 kDa (8.6 kDa calc mass) | Approximately 10% of pollen allergic patients displayed IgE reactivity to rPhl p 7 and Phl p 7-homologous allergens. - rPhl p 7 induced histamine release from basophils of three pollen allergic patients. - rPhl p 7 induced immediate type skin reactions these pollen allergic patients. | 10224228 | 2 | 2003-02-18 12:00:00 | 2019-09-05 22:49:38 | |
| Plantae Liliopsida (monocots) | Poales | Phleum pratense | Timothy | 504 | Phl p 11 | Ole e 1-related protein | 20 kDa | Phl p IX | IgE binding to rPhl p 11 was demonstrated in ImmunoCap test. 59 grass pollen-allergic subjects of 184 tested (32%) show IgE binding. rPhl p 11 inhibits 25% of the IgE binding to pollen extract. rPhl p 11 induces immediate skin reactions in 2 patients tested, and histamine release of basophils in 2 patients tested. | 12220472 | 2 | 2003-02-18 12:00:00 | 2019-09-05 22:55:54 |
| Plantae Liliopsida (monocots) | Poales | Phleum pratense | Timothy | 505 | Phl p 12 | Profilin | 14 kDa | Phl p 11 | Sera from 8 profilin-allergic individuals tested all showed IgE binding to rPhl p 12 on immunoblot (probably profilin allergic patients are sensitized initially against a certain profilin which then leads to cross-reactivity). | 8123000 | 2 | 2003-02-18 12:00:00 | 2019-09-05 22:56:12 |
| Plantae Liliopsida (monocots) | Poales | Phleum pratense | Timothy | 506 | Phl p 13 | Polygalacturonase | 55 kDa | All 5 grass pollen-allergic patients tested showed IgE binding to natural Phl p 13 in ELISA, 2 showed IgE binding to rPhl p 13. | 10691889 | 2 | 2003-02-18 12:00:00 | 2019-09-05 22:56:33 | |
| Animalia Chordata | Rodentia | Phodopus sungorus | Siberian hamster | 878 | Phod s 1 | lipocalin, odorant binding protein | 23 kDa | Skin prick test positive in 21 of 21 subjects with clinical history of allergy when exposed to inhalation of Siberian hamster caged animals and/or bites. Also 1 of 2 positives by BAT and 13 of 13 by IgE binding tests (ELISA and reducing immunoblots) | 21912180,24993820 | 2 | 2016-07-07 12:00:00 | 2024-09-16 18:46:07 | |
| Plantae Liliopsida (monocots) | Arecales | Phoenix dactylifera | Date palm | 512 | Pho d 2 | Profilin | 14 kDa | In ELISA, 16 out of 24 (66%) sera of date allergic patients showed IgE binding to purified date palm profilin. | 12028116 | 1 | 2003-03-13 12:00:00 | 2019-09-05 23:18:18 | |
| Plantae Pinopsida | Pinales | Pinus koraiensis | Korean pine | 882 | Pin k 2 | Vicilin | 48 kDa | Four of 14 pine-nut food challenge positive subjects in California had IgE binding to this protein as either native or reduced form by western blot. The protein was made as a recombinant protein in E. coli | 29195881 | 1 | 2016-10-28 13:40:32 | 2019-09-05 23:22:53 | |
| Plantae Pinopsida | Pinales | Pinus pinea | Stone pine | 842 | Pin p 1 | 2S albumin | 6 kDa (reducing) and 15 kDa (non-reducing) | 6 out of 8 pine nut-allergic patients tested positive for IgE binding using IgE Immunoblot and IgE ELISA. 3 out of 4 patients tested positive for basophil activation test. | 27211622 | 1 | 2015-10-01 12:00:00 | 2021-06-23 16:10:28 | |
| Plantae Pinopsida | Pinales | Pinus yunnanensis | Yunnan pine | 1166 | Pin y 2 | Vicilin-like seed storage protein, 7S globulin | 50 kDa | 20 sera from patients allergic to pine nuts (symptoms + SPT) were tested for IgE binding to Pinus yunnanensis seed extract by Western blot. Seven sera (35%) had IgE binding to a 50 kDa protein identified by mass spectrometry as vicilin. Five WB-positive sera were tested by ELISA with purified nPin y 2 and rPin y 2.0101 (expressed in E. coli). All five sera showed IgE binding to both allergens. | 41603857 | 1 | 2025-09-01 19:31:00 | 2026-01-30 18:02:17 | |
| Plantae Eudikotyledons | Sapindales | Pistacia vera | Pistachio | 515 | Pis v 1 | 2S albumin | 7 kDa | 19 of 28 pistachio allergic patients (68%) showed IgE binding to rPis v 1 on immunoblot. | 19522997 | 1 | 2007-02-08 12:00:00 | 2019-09-05 23:42:51 | |
| Plantae Eudikotyledons | Sapindales | Pistacia vera | Pistachio | 516 | Pis v 2 | 11S globulin subunit | 32 kDa | 14 of 28 pistachio allergic (50%) showed specific IgE binding to rPis v 2 on immunoblot. | 19522997 | 1 | 2007-02-08 12:00:00 | 2019-09-05 23:43:25 | |
| Plantae Eudikotyledons | Sapindales | Pistacia vera | Pistachio | 517 | Pis v 3 | vicillin | 55 kDa | 7 of 19 pistachio/cashew allergic (37%) showed specific IgE binding to rPis v 3 on dot blot. | 18479490 | 1 | 2007-06-05 12:00:00 | 2019-09-05 23:48:19 | |
| Plantae Eudikotyledons | Sapindales | Pistacia vera | Pistachio | 518 | Pis v 4 | manganese superoxide dismutase | 25.7 kDa | 10 (40%) out of the 25 pistachio allergic sera showed IgE binding to purified Pis v 4 on immunoblot. | 20567132 | 1 | 2007-09-25 12:00:00 | 2019-09-05 23:53:13 | |
| Plantae Eudikotyledons | Sapindales | Pistacia vera | Pistachio | 519 | Pis v 5 | 11S globulin subunit | 36 kDa (acidic subunit) | IgE form 10 of 28 pistachio allergic individuals reacted with the acidic subunit of Pis v 5.0101 on a 2D SDS gel. | 1 | 2008-02-08 12:00:00 | 2021-06-24 19:00:46 | ||
| Plantae Eudikotyledons | Fabales | Pisum sativum | Pea | 513 | Pis s 1 | Vicilin | 44 kDa | 77% of 18 pea allergic sera reacted with Pis s 1 from the crude extract on immunoblot. | 15544600 | 1 | 2006-11-03 12:00:00 | 2019-09-05 23:31:04 | |
| Plantae Eudikotyledons | Fabales | Pisum sativum | Pea | 514 | Pis s 2 | Convicilin | 63 kDa | 72% of 18 pea allergic sera reacted with Pis s 2 from the crude extract on immunoblot. | 15544600 | 1 | 2006-11-03 12:00:00 | 2019-09-05 23:34:18 | |
| Plantae Eudikotyledons | Fabales | Pisum sativum | Pea | 871 | Pis s 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9.5 kDa | 20 food allergic subjects tested for IgE binding to recombinant nsLTP1 of pea. Nine were food allergic to nuts or legumes including one who was reported to be allergic to ingested pea and the nine had significant IgE to Pru p 3, and also had IgE binding to pea nsLTP. | 27137920 | 1 | 2016-05-06 12:00:00 | 2025-04-10 18:05:41 | |
| Plantae Eudikotyledons | Lamiales | Plantago lanceolata | English plantain | 523 | Pla l 1 | Ole e 1-related protein | 18 kDa | 19 out of 22 sera analysed (86.4%) showed IgE binding to purified Pla l 1 in ELISA. Pla l 1 strongly inhibited IgE binding to whole plantain extract, up to 80%, in ELISA. | 11251634 | 2 | 2003-04-07 12:00:00 | 2020-05-13 22:04:06 | |
| Plantae Eudikotyledons | Lamiales | Plantago lanceolata | English plantain | 861 | Pla l 2 | Profilin | 15 kDa | Seventeen of 24 pollen allergic subject's sera showed IgE binding to purified natural profilin from Plantago lanceolata using reducing immunoblots | 28126622 | 2 | 2016-04-04 12:00:00 | 2019-09-06 00:04:26 | |
| Plantae basal Mesangiosperms | Proteales | Platanus acerifolia (Platanus x hispanica) | London plane tree | 520 | Pla a 1 | Putative invertase inhibitor | 18 kDa | Of 30 patients allergic to London plane tree pollen, 87% showed serum IgE binding to Pla a 1 on immunoblot of P. acerifolia extract. | 11906336 | 2 | 2003-04-10 12:00:00 | 2019-09-05 23:56:29 | |
| Plantae basal Mesangiosperms | Proteales | Platanus acerifolia (Platanus x hispanica) | London plane tree | 521 | Pla a 2 | Polygalacturonase | 43 kDa | Of 30 patients allergic to London plane tree pollen, 83% showed serum IgE binding to 43 kD protein on immunoblot of P. acerifolia extract. | 11906336 | 2 | 2003-04-08 12:00:00 | 2019-09-05 23:57:07 | |
| Plantae basal Mesangiosperms | Proteales | Platanus acerifolia (Platanus x hispanica) | London plane tree | 522 | Pla a 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | Of 58 plane pollen allergic patients, 45% showed IgE binding to purified nPla a 3 in immunoblot. The rates of sensitization to Pla a 3 in plane allergic patients with and without peach allergy were 61% and 18%, respectively. | 17250699 | 2 | 2006-11-05 12:00:00 | 2025-04-10 18:22:21 | |
| Plantae basal Mesangiosperms | Proteales | Platanus acerifolia (Platanus x hispanica) | London plane tree | 1113 | Pla a 4 | Profilin | 13.5 kDa | Thirty-nine P. acerifolia-sensitized patients with allergic rhinitis in spring were tested. All has positive SPT and sIgE (measured by ImmunoCAP) to plane tree pollen extract. Of those 30 (77%) had serum IgE to recombinant Pla a 4, measured by ELISA. The result was confirmed by IgE immunoblot with sera from 22 profilin-sensitized patients. Basophils from 3 of 4 profilin-sensitized patients reacted in a BAT assay with rPla a 4. | 35158224 | 2 | 2022-08-22 14:54:35 | 2022-08-22 18:23:20 | |
| Plantae basal Mesangiosperms | Proteales | Platanus acerifolia (Platanus x hispanica) | London plane tree | 1114 | Pla a 5 | Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase, AHCY) | 55 kDa | Twenty-three P. acerifolia-sensitized patients with allergic rhinitis in spring were tested. All has positive SPT and sIgE (measured by ImmunoCAP) to plane tree pollen extract. Of those 12 (52%) had serum IgE to recombinant Pla a 5, measured by ELISA. Natural purified Pla a 5 was tested by IgE immunoblot and yielded a positive signal in 4/7 (57%) tested sera. nPla a 5 was also tested by BAT and activated basophils from all three tested Pla a 5-sensitized patients. | 2 | 2022-08-22 17:37:14 | 2022-08-22 18:24:35 | ||
| Plantae basal Mesangiosperms | Proteales | Platanus acerifolia (Platanus x hispanica) | London plane tree | 1115 | Pla a 6 | Enolase | 48 kDa | Thirty-seven P. acerifolia-sensitized patients with allergic rhinitis in spring were tested. All has positive SPT and sIgE (measured by ImmunoCAP) to plane tree pollen extract. Of those 12 (32%) had serum IgE to natural Pla a 6, measured by immunoblot. Eleven of the 12 nPla a 6-reactive sera also recognized recombinant Pla a 6 in immunoblot. In a BAT assay, basophils from 4 of 5 Pla a 6-sensitized patients could be stimulated by nPla a 6. | 36252468 | 2 | 2022-08-22 18:18:41 | 2023-03-31 13:17:17 | |
| Plantae basal Mesangiosperms | Proteales | Platanus acerifolia (Platanus x hispanica) | London plane tree | 1116 | Pla a 7 | Triosephosphate isomerase (TIM) | 27 kDa | Fifty-eight P. acerifolia-sensitized patients with allergic rhinitis in spring were tested. All has positive SPT and sIgE (measured by ImmunoCAP) to plane tree pollen extract. Of those 24 (41%) had serum IgE to purified natural Pla a 7, measured by ELISA. IgE binding to natural and recombinant Pla a 7 was confirmed by IgE immunoblot with 5 Pla a 7-sensitized sera. nPla a 7 was also tested by BAT and activated basophils from all three tested Pla a 7-sensitized patients. | 37948987 | 2 | 2022-08-22 18:45:12 | 2024-09-17 17:12:05 | |
| Plantae basal Mesangiosperms | Proteales | Platanus acerifolia (Platanus x hispanica) | London plane tree | 1153 | Pla a 8 | Fructose-bisphosphate aldolase | 38 kDa | Sera from 20 plane tree pollen-allergic patients (allergic rhinitis and/or asthma, sIgE as measured by ImmunoCAP) were tested. Of those, 13 (65%) had IgE to rPla a 8.0101 measured by ELISA. In a Western blot, 5/6 and 4/6 ELISA-positive sera showed IgE binding to the natural and recombinant allergen, respectively. In an indirect BAT, rPla a 8.0101 activated basophils sensitized with sera from 3 ELISA-positive patients. In an inhibition ELISA with a serum pool, natural and recombinant Pla a 8 inhibited IgE binding to P. acerifolia pollen extract by 17%. | 2 | 2024-07-17 18:55:10 | 2024-07-17 18:58:42 | ||
| Plantae basal Mesangiosperms | Proteales | Platanus orientalis | Oriental plane tree | 524 | Pla or 1 | Plant invertase/pectin methylesterase inhibitor | 18 kDa | 3/19 oriental plane tree pollen allergic individuals had IgE that recognized natural Pla or 1 and recombinant Pla or 1 in IgE immunoblots. | 2 | 2008-07-12 12:00:00 | 2019-09-06 00:06:31 | ||
| Plantae basal Mesangiosperms | Proteales | Platanus orientalis | Oriental plane tree | 525 | Pla or 2 | Polygalacturonase | 42 kDa | 5/19 oriental plane tree pollen allergic individuals had IgE that recognized natural Pla or 2 and recombinant Pla or 2 in IgE immunoblots. | 2 | 2008-07-12 12:00:00 | 2019-09-06 00:07:18 | ||
| Plantae basal Mesangiosperms | Proteales | Platanus orientalis | Oriental plane tree | 526 | Pla or 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 11 kDa | 5/19 oriental plane tree pollen allergic individuals had IgE that recognized natural Pla or 3 and recombinant Pla or 3 in IgE immunoblots. | 2 | 2008-07-12 12:00:00 | 2025-04-10 18:07:06 | ||
| Animalia Arthropoda | Lepidoptera | Plodia interpunctella | Indianmeal moth | 527 | Plo i 1 | Arginine kinase | 40 kDa | rPlo I 1 reacted with serum IgE from 13 of the 52 (25%) moth-allergic patients by immunoblot and inhibited the binding of allergic patients’ IgE to an immunologically related 40-kDa allergen present in house dust mite, cockroach, king prawn, lobster, and mussel. | 11673567 | 2 | 2009-12-30 12:00:00 | 2019-09-06 00:14:40 | |
| Animalia Arthropoda | Lepidoptera | Plodia interpunctella | Indianmeal moth | 710 | Plo i 2 | Thioredoxin | 12 kDa | 7 of 154 indoor-allergic patients’ sera had IgE towards P. interpunctella thioredoxin on immunoblot. | 22844539 | 2 | 2011-02-09 12:00:00 | 2019-09-06 00:26:13 | |
| Plantae Liliopsida (monocots) | Poales | Poa pratensis | Kentucky blue grass | 528 | Poa p 1 | Beta-expansin | 33 kDa | IgE binding (5 different serum pools were used) to Poa pratensis grass pollen extract was inhibited (50-100%) by purified Poa p 1 in ELISA. | 2434551 | 2 | 2003-02-18 12:00:00 | 2019-09-06 00:27:21 | |
| Plantae Liliopsida (monocots) | Poales | Poa pratensis | Kentucky blue grass | 529 | Poa p 5 | 34 kDa | Poa p IX | IgE binding to Poa p 5 was shown using a pool of grass allergic sera, by SDS-PAGE immunoblotting - All sera from 55 grass pollen allergic individuals contained IgE antibodies to recombinant Poa p 5, as analyzed by enzyme immunoassay. See also medline 92306006 | 2051020 | 2 | 2003-02-18 12:00:00 | 2019-09-06 00:27:42 | |
| Animalia Arthropoda | Hymenoptera | Polistes annularis | Ringed paper wasp | 530 | Pol a 1 | Phospholipase A1B | 34 kDa | Allergenic cross-reactivity | 8828537 | 4 | 2003-05-31 12:00:00 | 2019-09-06 18:22:26 | |
| Animalia Arthropoda | Hymenoptera | Polistes annularis | Ringed paper wasp | 531 | Pol a 2 | Hyaluronidase | 38 kDa | Allergenic cross-reactivity | 8828537 | 4 | 2003-05-31 12:00:00 | 2019-09-06 18:23:39 | |
| Animalia Arthropoda | Hymenoptera | Polistes annularis | Ringed paper wasp | 532 | Pol a 5 | Antigen 5 | 23 kDa | Allergenic cross-reactivity | 8454859 | 4 | 2003-05-31 12:00:00 | 2019-09-06 18:24:13 | |
| Animalia Arthropoda | Hymenoptera | Polistes dominulus | Mediterranean paper wasp | 533 | Pol d 1 | Phospholipase A1 | 34 kDa | unpublished. Hoffman p.c. | 4 | 2003-05-31 12:00:00 | 2019-09-06 18:33:06 | ||
| Animalia Arthropoda | Hymenoptera | Polistes dominulus | Mediterranean paper wasp | 914 | Pol d 2 | Hyaluronidase | 50 kDa | 22 of 31 subjects with reactions to stings of Polistes dominulus were positive in IgE tests to recombinant Pol d 2 produced by Sf9 cells. This is not yet published. | 4 | 2017-12-21 23:07:18 | 2019-09-06 20:59:52 | ||
| Animalia Arthropoda | Hymenoptera | Polistes dominulus | Mediterranean paper wasp | 899 | Pol d 3 | Dipeptidyl peptidase IV | 100 kDa | 20/30 (66.7%) Spanish hymenoptera venom-allergic patients exhibited pronounced sIgE-reactivity with rPol d 3 by ELISA. | 29358620 | 4 | 2017-04-20 14:40:16 | 2019-09-06 21:11:57 | |
| Animalia Arthropoda | Hymenoptera | Polistes dominulus | Mediterranean paper wasp | 534 | Pol d 4 | Serine protease | 33 kDa | unpublished. Hoffman p.c. | 4 | 2003-05-31 12:00:00 | 2019-09-06 21:03:12 | ||
| Animalia Arthropoda | Hymenoptera | Polistes dominulus | Mediterranean paper wasp | 535 | Pol d 5 | Antigen 5 | 23 kDa | 4 | 2003-05-31 12:00:00 | 2019-09-06 18:44:39 | |||
| Animalia Arthropoda | Hymenoptera | Polistes exclamans | Guinea paper wasp | 536 | Pol e 1 | Phospholipase A1 | 34 kDa | All 19 sera from paper wasp-allergic patients showed IgE binding to purified Pol e 1 in RAST | 3989146 | 4 | 2003-06-03 12:00:00 | 2019-09-06 21:13:18 | |
| Animalia Arthropoda | Hymenoptera | Polistes exclamans | Guinea paper wasp | 537 | Pol e 4 | Serine protease | 33 kDa | 4 | 2003-06-03 12:00:00 | 2019-09-06 21:14:15 | |||
| Animalia Arthropoda | Hymenoptera | Polistes exclamans | Guinea paper wasp | 538 | Pol e 5 | Antigen 5 | 23 kDa | Of 19 paper wasp-allergic patients, 17 showed IgE binding to purified Pol e 5 in RAST. | 3989146 | 4 | 2003-06-03 12:00:00 | 2019-09-06 21:14:36 | |
| Animalia Arthropoda | Hymenoptera | Polistes fuscatus | Northern paper wasp | 539 | Pol f 5 | Antigen 5 | 23 kDa | Of 62 sera from Polistes-allergic patients, 43 showed IgE binding to P.fuscatus in RAST. The major cross-reactive allergen Pol f 5 was purified and characterized (medline 94044316) | 7065471 | 4 | 2003-06-03 12:00:00 | 2019-09-06 21:15:38 | |
| Animalia Arthropoda | Hymenoptera | Polistes gallicus | Paper wasp | 540 | Pol g 1 | Phospholipase A1 | 33.475 kDa by mass spec | Five allergic Italian patients sera showed significant IgE binding to purified Pol g 1 by EAST assay. | 14572904 | 4 | 2003-06-03 12:00:00 | 2019-09-06 21:31:06 | |
| Animalia Arthropoda | Hymenoptera | Polistes gallicus | Paper wasp | 541 | Pol g 5 | Antigen 5 | 24 kDa | Three allergic Italian patients sera showed significant IgE binding to purified Pol g 5 and two showed moderate binding by EAST assay. | 14572904 | 4 | 2003-06-03 12:00:00 | 2019-09-06 21:30:40 | |
| Animalia Arthropoda | Hymenoptera | Polistes metricus | Metricus paper wasp | 542 | Pol m 5 | Antigen 5 | 23 kDa | 7065471 | 4 | 2003-06-03 12:00:00 | 2019-09-06 21:32:24 | ||
| Animalia Arthropoda | Hymenoptera | Polybia paulista | Wasp | 543 | Poly p 1 | Phospholipase A1 | 34 kDa | Five P. paulista venom-sensitive patients’ sera recognized purified Poly p 1 by immunoblot. | 17761205 | 4 | 2007-02-18 12:00:00 | 2019-09-06 21:38:27 | |
| Animalia Arthropoda | Hymenoptera | Polybia paulista | Wasp | 896 | Poly p 2 | Hyaluronidase | 33 kDa | IgE binding from five subjects allergic to Polybia paulista by immunoblot | 22519534 | 4 | 2017-03-21 12:54:17 | 2019-09-06 21:39:30 | |
| Animalia Arthropoda | Hymenoptera | Polybia paulista | Wasp | 853 | Poly p 5 | Venom antigen 5 | 21.19 kDa | 11 out of 22 patients sera tested positive for IgE binding | 4 | 2015-11-23 12:00:00 | 2024-09-16 19:00:08 | ||
| Animalia Arthropoda | Hymenoptera | Polybia scutellaris | Wasp | 544 | Poly s 5 | 23 kDa | Ag 5 | Rat mast cell histamine release in response to P.scutellaris venom: 42.8% (40% spontaneous release). No induction of IgE response in rats after immunization with purified Pol s 5. | 4 | 2003-06-03 12:00:00 | 2019-09-06 21:43:28 | ||
| Animalia Arthropoda | Decapoda | Pontastacus leptodactylus | Narrow-clawed crayfish | 545 | Pon l 4 | Sarcoplasmic calcium-binding protein | ~24 kDa | 7/25 (28%) shrimp allergic patients had IgE that reacted with Pon l 4 in IgE immunoblots. | 1 | 2009-01-23 12:00:00 | 2019-09-06 21:46:39 | ||
| Animalia Arthropoda | Decapoda | Pontastacus leptodactylus | Narrow-clawed crayfish | 546 | Pon l 7 | Troponin I | ~30 kDa | 2/25 (8%) of shrimp allergic patients had IgE that reacted with Pon l 7 in IgE immunoblotting. | 1 | 2009-01-23 12:00:00 | 2019-09-06 21:49:11 | ||
| Plantae Eudikotyledons | Malpighiales | Populus nigra | Black poplar | 1007 | Pop n 2 | Profilin | 14.0 kDa | 25 subjects with pollen allergy were tested by SPT to extract of pollen and by IgE western blot using both natural and recombinant proteins. 20 of 25 were positive by western and/or ELISA. 18 of the 25 were positive by SPT. | 33210791 | 2 | 2020-03-04 16:20:51 | 2024-09-12 19:01:50 | |
| Animalia Arthropoda | Decapoda | Portunus pelagicus | Blue swimmer crab | 768 | Por p 1 | Tropomyosin | 39 kDa | Natural Por p 1 present in extracts of raw blue swimmer crab bound IgE from 7/13 sera of crab allergic individuals in immunoblotting. Natural Por p 1 present in extracts of cooked blue swimmer crab bound IgE from 9/13 sera of crab allergic individuals in immunoblotting. IgE binding to Por p 1 could be inhibited by the recombinant prawn tropomyosin rPen m 1.0101. | 23840718 | 1 | 2012-12-21 12:00:00 | 2019-09-06 21:54:34 | |
| Animalia Arthropoda | Decapoda | Portunus trituberculatus | Gazami crab | 1162 | Por t 4 | Sarcoplasmic Ca-binding protein (SCP) | 22 kDa | Sera from 15 crab-allergic patients (reported symptoms after ingestion of gazami crab + positive ImmunoCAP to snow crab) were tested. Five sera (33%) had IgE to purified natural Por t 4 in immunoblot. The positive sera also reacted to nPor t 4 and rPor t 4.0101 in an IgE-ELISA. | 37403834 | 1 | 2024-12-09 13:35:07 | 2024-12-09 13:35:07 | |
| Animalia Arthropoda | Decapoda | Procambarus clarkii | Red swamp crayfish | 928 | Pro c 1 | Tropomyosin | 36 kDa | Not well described allergic history. 21 of 30 patients had IgE binding to tropomyosin by ELISA and dot blot. Subjects were IgE positive to shrimp tropomyosin by ImmunoCAP. Sequence reference, Chen HL, Characterization of crayfish allergens APRI-2013. Unpublished. | 1 | 2018-04-28 21:52:35 | 2019-09-06 21:59:12 | ||
| Animalia Arthropoda | Decapoda | Procambarus clarkii | Red swamp crayfish | 929 | Pro c 2 | Arginine kinase | 40 kDa | Unclear Clinical reactivity. 17 of 28 patients with allergy to shrimp had IgE binding to this protein by ELISA and Dot blot. ImmunoCAP was positive to shrimp tropomyosin. 12 of 17 sera crustacean allergic sera reacted to the Por c 2 on the crude crayfish extract by immunoblot. | 24055770 | 1 | 2018-04-28 22:19:14 | 2019-09-06 22:08:40 | |
| Animalia Arthropoda | Decapoda | Procambarus clarkii | Red swamp crayfish | 930 | Pro c 5 | Myosin light chain 1 | 18 kDa | Unclear Clinical history. Seven of crustacean allergic patients had IgE binding to natural Pro c 5 by ELISA. | 26083097 | 1 | 2018-04-28 23:08:07 | 2019-09-06 22:14:21 | |
| Animalia Arthropoda | Decapoda | Procambarus clarkii | Red swamp crayfish | 927 | Pro c 8 | Triosephosphate isomerase | 28 kDa | Five of 13 human sera with poorly described history of allergy, except shrimp a by western and dot blots. Control sera were negative in IgE binding. The IgE bind was "lighter" that to Arginine Kinase of the this species in western blots. Publication in 2017 JAFC below. | 28072528 | 1 | 2018-04-28 19:30:04 | 2019-09-06 22:15:03 | |
| Plantae Eudikotyledons | Fabales | Prosopis juliflora | Mesquite | 839 | Pro j 1 | Ole e 1- like protein | 18 kDa | SPT positive in 27 of 48 subjects by SPT with extract of native pollen. IgE binding positive in reducing immunoblots with extract and with recombinant protein. | 27090365 | 2 | 2015-07-17 12:00:00 | 2019-09-06 22:20:14 | |
| Plantae Eudikotyledons | Fabales | Prosopis juliflora | Mesquite | 795 | Pro j 2 | Profilin | 14.3 kDa | Skin prick test with purified recombinant protein (in vivo); with 19 of 42 patients testing positive by SPT and serum IgE binding (in vitro) with 23 of 42 patients have positive IgE binding in reducing immunoblot. 17 of 35 mesquite pollen allergic patients (48.57%) had significant specific IgE level for rPro j 2. | 26141029 | 2 | 2014-06-02 12:00:00 | 2022-10-11 17:04:12 | |
| Plantae Eudikotyledons | Rosales | Prunus armeniaca | Apricot | 547 | Pru ar 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | N.A. | no data found | 1 | 2003-04-22 12:00:00 | 2013-06-04 17:39:28 | ||
| Plantae Eudikotyledons | Rosales | Prunus armeniaca | Apricot | 548 | Pru ar 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | 30 patients with oral allergy syndrome to apricot, with positive open food challenge responses, skin prick test responses, and serum-specific IgE antibodies to apricot, all recognized purified Pru ar 3 on immunoblot. | 10669861 | 1 | 2003-04-22 12:00:00 | 2025-04-10 18:24:29 | |
| Plantae Eudikotyledons | Rosales | Prunus armeniaca | Apricot | 953 | Pru ar 5 | Acidic Hev b 5-like protein | 17.4 kDa | Five subjects with IgE to Hev b 5 and with allergic reactions to consumption of apricot tested positive in FABER test to this protein, which was synthesized as a recombinant protein based on sequence of cDNA by Mbeguie-A-Mbeguie,D. and Fils-Lycaon,B.R. from accession AAD32205 of apricot. The submitter here (Maria Antonietta Ciardiello) indicated that teh recombinant protein migrated at 41 kDa in SDS-PAGE. | 1 | 2019-02-17 19:31:50 | 2025-08-26 14:50:04 | ||
| Plantae Eudikotyledons | Rosales | Prunus avium | Sweet cherry | 549 | Pru av 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 9 kDa | - 97 of 101 (96%)patients with birch pollinosis and oral allergy syndrom to cherry had IgE against rPru av 1, as measured by ELISA. - Induction of histamine release by basophils from cherry-allergic patients by rPru av 1: medline 98054114 - positive SPT responses with rPru av 1 in 22 (92%) of 24 patients with OAS to cherry: medline 22106233 | 11295665 | 1 | 2003-04-22 12:00:00 | 2019-09-06 22:32:19 | |
| Plantae Eudikotyledons | Rosales | Prunus avium | Sweet cherry | 550 | Pru av 2 | Thaumatin-like protein | 23 kDa | All 5 patient sera tested showed IgE binding to 30 kD Pru av 2 in immunoblot of cherry extract. | 9623505 | 1 | 2003-04-22 12:00:00 | 2019-09-06 22:35:01 | |
| Plantae Eudikotyledons | Rosales | Prunus avium | Sweet cherry | 551 | Pru av 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | - 3 (3%) of 101 German patients with clinical history of oral allergy syndrome to cherry had serum IgE against rPru av 3, as measured by ELISA. 7 Italian patients tested all had IgE against rPru av 3. - 1 (4%) of 24 patients with OAS to cherry had positive SPT to rPru av 3: medline 22106233 | 11295665 | 1 | 2003-04-24 12:00:00 | 2025-04-10 18:23:33 | |
| Plantae Eudikotyledons | Rosales | Prunus avium | Sweet cherry | 552 | Pru av 4 | Profilin | 15 kDa | - 16 of 101 (16.2%) patients with birch pollinosis and oral allergy syndrome to cherry had IgE against rPru av 4, as measured by ELISA - 4 (17%) of 24 patients with OAS to cherry had positive SPT responses to rPru av 4: medline 22106233 | 11295665 | 1 | 2003-04-22 12:00:00 | 2019-09-06 22:36:00 | |
| Plantae Eudikotyledons | Rosales | Prunus avium | Sweet cherry | 1002 | Pru av 7 | Gibberellin-regulated protein | 9 kDa | 11 of 25 sweet cherry allergic subjects in Japan who were diagnosed based on clinical history, or SPT and IgE to cherry proteins, were test positive by BAT and IgE with this natural protein. The protein was purified by chromatography. ELISA and BAT tests werre perormed including to nPru p 7. The peptide sequence (GSSFCDSKCGVRCSKAGYKE)matched mature protein expected from the genomic sequence of cherry. | 1 | 2020-01-26 00:10:58 | 2020-01-26 14:52:19 | ||
| Plantae Eudikotyledons | Rosales | Prunus domestica | European plum | 553 | Pru d 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | Of 23 plum-allergic patients tested, 19 (83%) showed serum IgE binding to a 9 kD protein in plum extract on immunoblot. This 9 kD allergen was identified as Pru d 3 by N-terminal sequence analysis. | 11419731 | 1 | 2003-04-24 12:00:00 | 2025-04-10 18:23:03 | |
| Plantae Eudikotyledons | Rosales | Prunus dulcis | Almond | 1078 | Pru du 1 | PR-10, Bet v 1-related protein | 18 kDa | 14 of 17 almond allergic subjects had IgE binding to this recombinant protein expressed in E. coli by IgE ELISA, and there were two negative controls. Expression in almond kernels was confirmed by tandem MS, and the sequence matched the genomic sequence "Pru du 1.06A" identified by Li et al. in PMID 19014629. | 35949989 | 1 | 2021-10-28 04:08:11 | 2024-12-04 16:34:23 | |
| Plantae Eudikotyledons | Rosales | Prunus dulcis | Almond | 554 | Pru du 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | 1 | 2009-09-23 12:00:00 | 2025-04-10 18:23:55 | |||
| Plantae Eudikotyledons | Rosales | Prunus dulcis | Almond | 555 | Pru du 4 | Profilin | 14 kDa | 8 of 18 (44%) sera reacted with almond nut Pru du 4 by dot-blot analysis and ELISA | 17030246 | 1 | 2006-11-03 12:00:00 | 2019-09-07 00:23:19 | |
| Plantae Eudikotyledons | Rosales | Prunus dulcis | Almond | 556 | Pru du 5 | 60s acidic ribosomal prot. P2 | 10 kDa | 1 | 2007-02-18 12:00:00 | 2019-09-07 00:37:51 | |||
| Plantae Eudikotyledons | Rosales | Prunus dulcis | Almond | 663 | Pru du 6 | Amandin, 11S globulin, legumin-like protein | 360 kDa (hexamer) | 1 | 2010-01-25 12:00:00 | 2022-04-06 16:40:44 | |||
| Plantae Eudikotyledons | Rosales | Prunus dulcis | Almond | 944 | Pru du 8 | Alpha-hairpinin | 31 kDa | Sera were collected from 18 patients diagnosed to be allergic to almond by double-blind placebo-controlled food challenges. Among these, 6 sera (33%) contained IgE antibodies against recombinant Pru du 8 as determined by immunoblot. | 31287307 | 1 | 2018-10-30 01:31:37 | 2026-02-11 15:55:46 | |
| Plantae Eudikotyledons | Rosales | Prunus dulcis | Almond | 999 | Pru du 10 | Mandelonitrile lyase 2; Hydroxynitrile lyase | 60 kDa | History of recent allergic response to almond ingestion. 13 of 18 subjects with allergy to almonds were positive by IgE ELISA, 2 were positive by western blot. There were 4 neg controls. Some IgE binding was inhibited by glycan. | 33020913 | 1 | 2019-12-26 02:12:53 | 2022-05-10 18:40:05 | |
| Plantae Eudikotyledons | Rosales | Prunus mume | Japanese apricot | 886 | Pru m 7 | gibberellin-regulated protein, peamaclein | 6.9 kDa | possible FDEIA after consuming Japanese apricot, seven patients mean age 28.6 yrs, clinical history and SPT and/or challenge. ELISA positive using ImmunoCAP with peach proteins Pru p 1, Pru p 3 and Pru p 4. Also BAT to JA peamaclein. They evaluated cross-reactivity with Pru p 7. 85% were positive by rPru p 7, also JA peamaclein induced CD203c in BAT in four subjects. | 28685994 | 1 | 2016-11-22 20:47:06 | 2024-09-16 18:53:19 | |
| Plantae Eudikotyledons | Rosales | Prunus persica | Peach | 557 | Pru p 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 18 kDa | Submission to the I.U.I.S. Allergen Nomenclature Sub-Committee | 1 | 2007-06-05 12:00:00 | 2019-09-07 01:18:59 | ||
| Plantae Eudikotyledons | Rosales | Prunus persica | Peach | 664 | Pru p 2 | Thaumatin-like protein | 25-28 kDa | 1 | 2010-02-01 12:00:00 | 2019-09-07 01:19:39 | |||
| Plantae Eudikotyledons | Rosales | Prunus persica | Peach | 558 | Pru p 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 10 kDa | - Of 29 peach-allergic patients, 14 had positive skin prick test in response to purified Pru d 3. - In immunoblot of peach extract, all 15 sera of patients with OAS to peach tested, showed IgE binding to Pru p 3 (verified by N-terminal sequencing): medline 99169150. - Basophil activation and induction of sulphidoleukotriene production by both natural and rPru p 3 in 9 of 10 patients tested. Histamine release was induced in at least half of the patients: medline 22529215 | 10614824 | 1 | 2003-04-24 12:00:00 | 2025-04-10 18:24:12 | |
| Plantae Eudikotyledons | Rosales | Prunus persica | Peach | 559 | Pru p 4 | Profilin | 14 kDa | - Of 29 sera from peach-allergic patients (clinical history and positive SPT), 15 showed IgE binding to rPru p 4.01 on immunoblot - Peach profilin was not recognized on immunoblot of peach extract, probed with a pool of sera from patients with high IgE titers against peach allergens: medline 92378047. | 12823124 | 1 | 2003-04-24 12:00:00 | 2019-09-07 01:20:37 | |
| Plantae Eudikotyledons | Rosales | Prunus persica | Peach | 761 | Pru p 7 | Gibberellin-regulated protein (PF02704) | 6910.84 Da (mass spectrometry, mature protein) | 14 of 33 peach allergic individuals had a positive skin test reaction when tested with purified natural Pru p 7. Sera from 9 of 33 individuals had IgE that reacted with purified natural Pru p 7 in an allergen micro-beads array. | 1 | 2012-09-12 12:00:00 | 2019-09-07 01:21:21 | ||
| Plantae Eudikotyledons | Rosales | Prunus persica | Peach | 947 | Pru p 9 | Pathogenesis-related protein PR-1 | 18 kDa | Nine of 24 subjects with allergy to peach pollen as shown by symptoms, SPT and, in some, nasal challenges were positive in IgE tests of western blots, 2 negative controls were negative. 24 of 129 patients were SPT positive to pollen extract. | 32191737 | 2 | 2018-12-11 21:26:41 | 2025-08-25 19:16:37 | |
| Plantae Eudikotyledons | Rosales | Prunus persica | Peach | 1080 | Pru p 10 | Polygalacturonase | 46 kDa | Seven of eight subjects with inhalation allergy to peach pollen were positive to natural, purified protein. There were two negative controls. The protein was purified from PBS extract and Cation exchange chromatography, with PBS pH 7 on FPLC. | 2 | 2021-11-17 21:55:37 | 2025-10-21 13:24:03 | ||
| Fungi Basidiomycota | Agaricales | Psilocybe cubensis | Magic mushroom | 560 | Psi c 1 | 2 | 2010-01-27 12:00:00 | 2024-06-28 17:49:47 | |||||
| Fungi Basidiomycota | Agaricales | Psilocybe cubensis | Magic mushroom | 561 | Psi c 2 | Cyclophilin | 16 kDa | SDS-PAGE immunoprints conducted with 11 P.cubensis skin test- and RAST-positive sera demonstrated 18 IgE-binding bands; most sera (82%) reacted to a 16 kD allergen. This 16 kD allergen was later identified as cyclophilin Psi c 2 (medline 95337761) | 8453314 | 2 | 2003-09-01 12:00:00 | 2019-09-07 01:26:38 | |
| Plantae Eudikotyledons | Myrtales | Punica granatum | Pomegranate | 773 | Pun g 1 | Non-specific lipid transfer protein 1 (nsLTP1) | 9 kDa | 1 | 2013-04-25 12:00:00 | 2019-09-07 01:29:59 | |||
| Plantae Eudikotyledons | Myrtales | Punica granatum | Pomegranate | 936 | Pun g 7 | Gibberellin regulated protein, pommaclein | 7 kDa | IgE binding to natural purified protein by 4 of 19 subjects with claims of allergy to consumption of pomegranate. Five subjects of 8 were positive by SPT with extract of pomegranate. | 28290690 | 1 | 2018-09-07 18:22:35 | 2025-08-25 19:18:18 | |
| Plantae Eudikotyledons | Myrtales | Punica granatum | Pomegranate | 1001 | Pun g 14 | Chitinase III | 29 kDa | Five of 10 subjects allergic to pomegranate pulp extract were positive to Pun g 14 by IgE binding by dot-blotting, 8 were positive by immunoblotting. The protein is highly identical to Hev b 14 and to raspberry chitinase. Based on FABER tests of 357 patients, 214 were positive to Pun g 1, 69 to Pun g 16, 44 to Pun g 7, 20 to another protein they called Pun g 5. And 161 to pomegranate seed. | 30241023 | 1 | 2020-01-23 04:47:17 | 2020-01-23 04:49:31 | |
| Plantae Eudikotyledons | Rosales | Pyrus communis | Pear | 562 | Pyr c 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 18 kDa | Induction of basophil histamine release by rPyr c 1 in two patients allergic to pears. - rPyr c 1 and natural Pyr c 1 were recognized by specific IgE from sera of all 16 pear-allergic patients tested. | 11419719 | 1 | 2003-04-24 12:00:00 | 2019-09-07 01:33:14 | |
| Plantae Eudikotyledons | Rosales | Pyrus communis | Pear | 563 | Pyr c 3 | Nonspecific lipid transfer protein type 1 (nsLTP1) | 9 kDa | No data found | 22015956 | 1 | 2003-04-24 12:00:00 | 2025-04-10 18:25:17 | |
| Plantae Eudikotyledons | Rosales | Pyrus communis | Pear | 564 | Pyr c 4 | Profilin | 14 kDa | Cross-reactivity with Bet v 2 (birch pollen profilin): 43 of 49 patients (88%), preselected for an IgE-reactivity with Bet v 2 showed specific IgE-antibodies to rPyr c 4. Positive in cellular mediator release test. | 11419723 | 1 | 2003-04-24 12:00:00 | 2019-09-07 02:30:39 | |
| Plantae Eudikotyledons | Rosales | Pyrus communis | Pear | 565 | Pyr c 5 | Isoflavone reductase related protein, putative phenylcoumaran benzylic ether reductase | 34 kDa | rPyr c 5 bound to serum IgE of 10 birch-pollen-allergic patients in immunoblotting experiments. rPyr c 5 induced basophil histamine release in 1 patient tested. | 11606193 | 1 | 2003-04-24 12:00:00 | 2019-09-07 02:31:07 | |
| Plantae Eudikotyledons | Fagales | Quercus acutissima | Sawtooth oak | 1047 | Que ac 1 | Pathogenesis-related protein PR-10; Bet v 1-related protein | 17 kDa | 22 of 24 Korean subjects with airway allergy at pollination time were positive by serum IgE tests by ELISA and western blots to recombinant protein. | 34002418 | 2 | 2021-01-21 17:51:26 | 2024-12-04 17:05:06 | |
| Plantae Eudikotyledons | Fagales | Quercus acutissima | Sawtooth oak | 1052 | Que ac 2 | Profilin | 16 kDa | Six of 50 patients with inhalation allergy were tested by IgE binding to recombinant protein were positive inbinding as measured by RAST or EAST. | 34002418 | 2 | 2021-03-18 16:06:40 | 2024-12-04 17:06:39 | |
| Plantae Eudikotyledons | Fagales | Quercus alba | White oak | 566 | Que a 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 17 kDa | - 7 out of 11 sera from tree pollen allergic patients (with a well-characterized IgE reactivity profile to birch pollen allergens) showed IgE binding to Que a 1 on immunoblot of oak pollen extract. This IgE binding could be inhibited by recombinant Bet v 1. | 9802365 | 2 | 2003-03-27 12:00:00 | 2019-09-07 02:31:30 | |
| Plantae Eudikotyledons | Fagales | Quercus ilex | Holly oak, holm oak | 990 | Que i 1 | Pathogenesis-related protein PR-10; Bet v 1-related protein | 21 kDa | Size is based on histag recombinant protein, calculated MW is 17.4 kDa. 21 of 38 patients with symptoms were positive for IgE to this recombinant protein by reducing and non-reducing immunoblot. Recombinant protein sequence confirmed by LC-MSMS with 55.3% coverage. | 32511782 | 2 | 2019-11-22 17:15:15 | 2021-10-12 14:45:35 | |
| Plantae Eudikotyledons | Fagales | Quercus ilex | Holly oak, holm oak | 1163 | Que i 2 | Profilin | 13 kDa | Forty pollen allergic patients from Spain with allergic symptoms during the Quecus ilex flowering season (spring) and positive SPT to Q. ilex extract were tested. In an IgE dot-blot, 14 sera (35%) bound to rQue i 2.0101. Of 29 sera tested by ELISA with rQue i 2.0101, 10 (34%) had sIgE to the allergen. | 2 | 2025-04-10 15:31:00 | 2025-04-10 15:31:00 | ||
| Plantae Eudikotyledons | Fagales | Quercus ilex | Holly oak, holm oak | 1188 | Que i 6 | Isoflavone reductase-like protein | 34 kDa | Sera from eighty-four patients allergic to holm oak pollen (symptoms in spring + positive SPT to Q. ilex pollen extract) were tested. Of those, 11 sera (13%) had IgE to recombinant Que i 6, expressed in E. coli. The recombinant allergen partially inhibited IgE binding to Q. ilex pollen extract in a Western blot with a pool of 10 sera. | 2 | 2026-04-22 12:42:19 | 2026-04-22 12:42:19 | ||
| Plantae Eudikotyledons | Fagales | Quercus mongolica | Mongolian oak | 952 | Que m 1 | Pathogenesis-related protein PR-10; Bet v 1-related protein | 17 kDa | 46 of 50 patients positive by ELISA to recombinant protein from SPT positive subjects in Korea. 3 subjects positive by basophil activation by recombinant protein and by SPT to extract of the Mongolian Oak were used in tests and quite sensitive as described in their 2017 IAAI publication. | 29065418 | 2 | 2019-01-18 16:53:53 | 2021-10-12 14:34:58 | |
| Animalia Chordata | Anura | Rana esculenta (Pelophylax esculentus) | Edible frog | 567 | Ran e 1 | Alpha-parvalbumin | 11.9 kDa | The patients serum IgE antibodies recognized parvalbumin prepared from frog muscle and recombinant alpha parvalbumin from R. species but not from R. esculenta. | 12359003 | 1 | 2004-10-27 12:00:00 | 2019-09-07 02:33:35 | |
| Animalia Chordata | Anura | Rana esculenta (Pelophylax esculentus) | Edible frog | 568 | Ran e 2 | Beta-parvalbumin | 11.7 kDa | The patients serum IgE antibodies recognized parvalbumin prepared from frog muscle and recombinant alpha parvalbumin from R. species but not from R. esculenta. Recombinant beta parvalbumin was not recognized by the IgE antibodies. | 12359003 | 1 | 2004-10-27 12:00:00 | 2019-09-07 02:33:50 | |
| Animalia Mollusca | Neogastropoda | Rapana venosa | Veined rapa whelk | 1040 | Rap v 2 | Paramyosin | 99 kDa | Five subjects allergic to consumption of sea snails were included in the study, and they IgE to this species and four had reported allergy to Rapana venosa, one was also positive by IgE to molluscan extract. Two individuals without allergy and one with allergy to shell fish were used as negative controls. Two of the subjects were SPT+ in tests at 5 mm from prick to prick tests with muscle tissue of welk. Four of the 8 subjects in IgE tests were positive in western blot of extract. This data is published in J Agric Food Chem . 2020 Nov 11. doi: 10.1021/acs.jafc.0c04418. | 33175512 | 1 | 2020-11-24 22:56:01 | 2020-11-24 22:56:31 | |
| Animalia Chordata | Scombriformes | Rastrelliger kanagurta | Indian mackerel | 879 | Ras k 1 | Parvalbumin | 11.3 kDa | Fifteen of 18 fish allergic subjects had IgE binding to natural, purified, raw parvalbumin on SDS-PAGE | 29193486 | 1 | 2016-08-28 12:00:00 | 2019-09-07 02:37:38 | |
| Animalia Chordata | Rodentia | Rattus norvegicus | Rat | 569 | Rat n 1 | Lipocalin and Alpha-2u-globulin | 17 kDa | MUP | Serum IgE binding of 15 rat-allergic patients to Rat n 1 peptides in ELISA - >90% of 83 patients tested showed IgE binding to Rat n 1 on immunoblot See also medline 93352986 | 10574630 8645715 | 2 | 2003-02-05 12:00:00 | 2020-05-14 23:49:51 |
| Fungi Mucoromycota | Mucorales | Rhizopus oryzae | Bread mold | 805 | Rhi o 1 | Aspartyl endopeptidase | 44 kDa | 132 airway allergic subjects in India were challenged by SPT with extract of cultured hyphae, 62 were positive, then 60 were SPT challenged with natural and recombinant protein. Sixteen of 20 SPT positive subjects had serum IgE binding positive to purified protein. Publication PMID 23041133 describes preliminary tests and protein. Full allergenicity information is being submitted | 23041133, 26672984, 27358405 | 2 | 2016-01-05 12:00:00 | 2019-09-07 02:45:50 | |
| Fungi Mucoromycota | Mucorales | Rhizopus oryzae | Bread mold | 862 | Rhi o 2 | Cyclophilin | 18 kDa | 74 of 114 case history positive subjects (inhalation and skin contact) sensitized to diverse sources such as R. oryzae, birch, Malassezia, Alternaria and Aspergillus were tested for IgE binding to recombinant 18 kD protein from cloned cyclophilin of bread mold Rhizopus oryzae. Interestingly, within 74 patients, 38 sera from 38 R. oryzae sensitized subjects were IgE-reactive to this allergen. In addition, 6 of 6 were positive in RBL degranulation assay. 3 of 3 by BAT CD203c | 31882546 | 2 | 2016-02-20 12:00:00 | 2020-01-18 20:09:17 | |
| Fungi Basidiomycota | Sporidiobolales | Rhodotorula mucilaginosa | Yeast | 570 | Rho m 1 | Enolase | 47 kDa | Sera from 3 (21%) of 14 allergic patients sensitized to R. mucilaginosa showed IgE binding to 47kD Rho m 1 in R.mucilaginosa extract on immunoblot. These sera also showed IgE binding to rRho m 1. | 12432231 | 2 | 2003-10-28 12:00:00 | 2019-09-07 02:55:05 | |
| Fungi Basidiomycota | Sporidiobolales | Rhodotorula mucilaginosa | Yeast | 571 | Rho m 2 | vacuolar serine protease | 31 kDa | Among 44 bronchial asthmatic patients sera with IgE reactivity against crude R. mucilaginosa extract, 25 (57%) demonstrated IgE binding against Rho m 2. | 16179794 | 2 | 2006-02-26 12:00:00 | 2019-09-07 03:01:17 | |
| Plantae Eudikotyledons | Malpighiales | Ricinus communis | Castor bean | 572 | Ric c 1 | 2S albumin | 11 kDa | High frequency of IgE binding to purified Ric c 1 in ELISA. Bashir MEH: Immunological and structural studies of Ric c 1 and Ric c 3, the major allergens of Ricinus communis, var.Pacific-6; PhD thesis; University of Saarland, 1997 | 2274038 | 1 | 2003-08-08 12:00:00 | 2019-09-07 03:07:32 | |
| Plantae Eudikotyledons | Rosales | Rubus idaeus | Red raspberry | 573 | Rub i 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 17 kDa | 1 | 2007-02-18 12:00:00 | 2019-09-07 03:10:22 | |||
| Plantae Eudikotyledons | Rosales | Rubus idaeus | Red raspberry | 574 | Rub i 3 | Non-specific lipid transfer protein 1 (nsLTP1) | 11 kDa | 1 | 2007-02-18 12:00:00 | 2019-09-07 03:10:37 | |||
| Animalia Mollusca | Ostreida | Saccostrea glomerata | Sydney rock oyster | 919 | Sac g 1 | Tropomyosin | 38 kDa | Fourteen of 19 subjects with history of allergy to molluskan shellfish were positive in IgE binding of native purified protein in reducing immunoblots and 3 negative controls were negative. The 19 subjects were all positive in RAST to oyster. Two of two subjects had positive direct basophil activation tests with natural protein, one control was tested and found negative. | 29756679 | 1 | 2018-02-05 21:12:58 | 2019-09-07 03:11:43 | |
| Animalia Chordata | Salmoniformes | Salmo salar | Atlantic salmon | 580 | Sal s 1 | Beta-parvalbumin 1 | 12 kDa | 7 out of 11 cod-allergic patients showed IgE binding to Sal s 1 on immunoblot. | 8845026 | 1 | 2003-08-08 12:00:00 | 2019-09-07 07:35:45 | |
| Animalia Chordata | Salmoniformes | Salmo salar | Atlantic salmon | 733 | Sal s 2 | Beta-Enolase | 47.3 kDa | 24% of individuals with a convincing history of fish allergy had IgE that reacted with natural purified Sal s 2 in ELISA. | 23786287 | 1 | 2011-08-26 12:00:00 | 2020-05-14 23:55:16 | |
| Animalia Chordata | Salmoniformes | Salmo salar | Atlantic salmon | 750 | Sal s 3 | Aldolase A | 40 kDa | 10/62 (16%) individuals with a convincing history of fish allergy had IgE reacting with purified natural Sal s 3. | 23786287 | 1 | 2012-07-30 12:00:00 | 2020-05-14 23:59:35 | |
| Animalia Chordata | Salmoniformes | Salmo salar | Atlantic salmon | 992 | Sal s 4 | Tropomyosin | 37 kDa | 20 subjects with history of allergy to salmon consistent with IgE mediated allergy to Atlantic salmon. These were tested by SPT to salmon and western blot to extract of salmon muscle, binding to tropomyosin by western blot. | 32860256 | 1 | 2019-11-25 23:23:23 | 2025-08-25 19:26:16 | |
| Animalia Chordata | Salmoniformes | Salmo salar | Atlantic salmon | 956 | Sal s 6 | Collagen alpha | 130-140 kDa | Sera of 87 fish-allergic patients were tested for IgE binding to a pool of barramundi, Atlantic salmon and Yellowfin tuna collagens by ELISA. 19 patients were positive. Of those, 13 sera were tested in immunoblots to check IgE binding to collagen from specific fish species and to specific collagen alpha chains. Of 13 sera tested in immunoblot, IgE from 11 bound to collagen alpha 1 and alpha 2 chains from muscle and skin tissue of Atlantic salmon. Basophil activation test was performed with whole blood of one of the collagen-sensitized patients, using salmon muscle collagen as stimulant of basophils. The result was positive. | 32389794 | 1 | 2019-04-19 23:43:33 | 2024-07-11 12:52:25 | |
| Animalia Chordata | Salmoniformes | Salmo salar | Atlantic salmon | 993 | Sal s 7 | Creatine kinase | 43 kDa | Twenty patients reported typical IgE-mediated allergic reactions after ingestion of Atlantic salmon (Salmo salar). As negative controls, 2 non-atopic individuals without history of type I allergy and 3 individuals with allergy to shellfish but not fish were used. Among those, none indemonstrated IgE reactivity to the 43 kDa band. Based on our findings, we request to recongise salmon creatine kinase as fish allergen Sal s 7.01. | 32860256 | 1 | 2019-11-25 23:48:44 | 2021-06-18 16:17:50 | |
| Animalia Chordata | Salmoniformes | Salmo salar | Atlantic salmon | 994 | Sal s 8 | Triosephosphate isomerase | 25 kDa | 26 of 77 fish allergic subjects had IgE binding to the 25 kDa protein. However, only 20 were recognized as allergic to salmon. Therefore some cross-reactivity. | 32860256 | 1 | 2019-11-26 00:01:44 | 2021-01-11 17:03:10 | |
| Plantae Eudikotyledons | Caryophyllales | Salsola kali | Prickly saltwort | 575 | Sal k 1 | Pectin methylesterase | 43 kDa | Of 39 individuals with a positive specific IgE determination to S. kali, 26 (66.6%) had detectable specific IgE to Sal k 1. 20 of these 39 individuals were skin-prick tested with the purified allergen and all of them had a positive skin test to the purified allergen. | 14616126 | 2 | 2003-04-17 12:00:00 | 2019-09-07 03:14:10 | |
| Plantae Eudikotyledons | Caryophyllales | Salsola kali | Prickly saltwort | 576 | Sal k 2 | Protein kinase homologue | 36 kDa | 2 | 2003-04-17 12:00:00 | 2019-09-07 03:15:32 | |||
| Plantae Eudikotyledons | Caryophyllales | Salsola kali | Prickly saltwort | 577 | Sal k 3 | Cobalamin independent methionine synthase | 39+45 kDa | 8/12 (66.6%) of S. kali allergic patients had specific IgE to purified rSal k 3. | 20238167 | 2 | 2009-09-08 12:00:00 | 2019-09-07 07:09:15 | |
| Plantae Eudikotyledons | Caryophyllales | Salsola kali | Prickly saltwort | 578 | Sal k 4 | Profilin | 14 kDa | 14 (46.6%) individual S. kali pollen allergic sera showed IgE binding to the natural form of Sal k 4 in crude S. kali pollen extract and purified rSal k 4 by immunoblot. | 20622444 | 2 | 2009-09-08 12:00:00 | 2020-05-13 22:07:28 | |
| Plantae Eudikotyledons | Caryophyllales | Salsola kali | Prickly saltwort | 579 | Sal k 5 | Ole e 1-like protein | 18.2 kDa | 64% of 28 patients from Murcia (Spain) and 34% of 28 patients from Zargoza (Spain), all of them allergic to Salsola kali pollen, had IgE that reacted with Sal k 5 in ELISA. Sal k 5 shows high IgE cross-reactivity with the homologous allergen Che a 1 (Chenopodium album) and very low cross-reactivity with the homologous allergen Ole e 1 (Olea europaea). | 24356442 | 2 | 2009-11-27 12:00:00 | 2019-09-07 07:21:47 | |
| Plantae Eudikotyledons | Caryophyllales | Salsola kali | Prickly saltwort | 901 | Sal k 6 | Polygalacturonase | 47 kDa cleaves to 28 kDa | Subjects with case history of allergy to Russian Thistle pollen, IgE binding by in vitro IgE tests in 28 of 88 subjects using recombinant E. coli produced protein in ELISA. Unclear about Cell tests. BBA-Proteins and Proteomics available online May 30 2017. They also had 2 positive of 2 tested by BAT. | 28502749 | 2 | 2017-06-01 07:49:04 | 2019-09-07 07:23:20 | |
| Plantae Eudikotyledons | Caryophyllales | Salsola kali | Prickly saltwort | 897 | Sal k 7 | Polcalcin | 8.5 kDa | Eight positive IgE binding sera out of 20 allergic subjects | 2 | 2017-03-24 15:44:06 | 2025-08-25 19:22:00 | ||
| Animalia Chordata | Clupeiformes | Sardinops sagax | Pacific pilchard | 581 | Sar sa 1 | Beta-parvalbumin | 12 kDa | 8 of 10 fish allergic individuals had IgE that bound natural purified beta-parvalbumin from Pacific pilchard. | 19616851 | 1 | 2008-12-02 12:00:00 | 2019-09-24 06:57:47 | |
| Fungi Basidiomycota | Agaricales | Schizophyllum commune | 746 | Sch c 1 | Glucoamylase | 61 kDa | 4 of 5 patients with chronicpulmonary aspergillosiss had IgE binding to rSch c 1 by immunoblot. | 24372664 | 2 | 2012-07-13 12:00:00 | 2019-09-07 08:05:41 | ||
| Animalia Arthropoda | Scolopendromorpha | Scolopendra mutilans | Chinese red-headed centipede | 954 | Sco m 5 | Venom allergen 5 | 20 kDa | Five of six patients with reactivity to centipede stings were positive in IgE binding by reducing immunoblot to purified natural protein. Four of six were positive by SPT to native purified protien equal to histamine control. | 4 | 2019-02-17 21:07:55 | 2020-01-23 21:15:12 | ||
| Animalia Chordata | Scombriformes | Scomber scombrus | Atlantic mackerel | 948 | Sco s 1 | Parvalbumin | 12 kDa | 18 of 19 subjects with a history of allergy to consumption of Atlantic mackerel were positive in IgE binding to native protein by ELISA. The protein was characterized by immunoblot with anti-parvalbumin antibody and protein verified by Edman degradation and Mass Spectrometry. Data was presented at the ISMA meeting in Rome in 2007 and at the EAACI Congress in Vienna in 2016 | 1 | 2018-12-17 20:04:16 | 2019-09-07 08:13:54 | ||
| Animalia Arthropoda | Decapoda | Scylla paramamosain | Green mud crab | 1053 | Scy p 1 | Tropomyosin | 38 kDa | 41 of 50 Subjects allergic to crustaceans had IgE binding to recombinant and natural tropomyosin of Scylla paramyosin by dot blot, western blot, ImmunoCAP | 30107732 | 1 | 2021-03-20 20:10:05 | 2021-03-20 21:14:24 | |
| Animalia Arthropoda | Decapoda | Scylla paramamosain | Green mud crab | 931 | Scy p 2 | Arginine kinase | 40 kDa | Not well characterized clinical history. 21 of 30 patients with allergy to crustaceans had IgE binding to this protein by ELISA and dot blot. | 25728640 | 1 | 2018-04-28 23:37:37 | 2019-09-07 08:15:16 | |
| Animalia Arthropoda | Decapoda | Scylla paramamosain | Green mud crab | 1054 | Scy p 3 | Myosin light chain | 18 kDa | 19 of 35 subjects allergic to crustaceans were positive in IgE binding to recombinant and natural protein by ImmunoCAP, ELISA and dot blot | 31469568 | 1 | 2021-03-20 21:06:55 | 2021-03-20 21:07:21 | |
| Animalia Arthropoda | Decapoda | Scylla paramamosain | Green mud crab | 932 | Scy p 4 | Sarcoplasmic Ca+ binding protein | 20 kDa | Sera from 22 crustacean allergic subjects were tested and more. IgE binding was by ELISA and Dot blot. 24 of 61 patients were positive. | 28692255 | 1 | 2018-04-29 00:07:00 | 2019-09-07 08:23:32 | |
| Animalia Arthropoda | Decapoda | Scylla paramamosain | Green mud crab | 933 | Scy p 8 | Triosephosphate isomerase | 28 kDa | Unclear history of crustacean shellfish allergy. Six of 30 subject's sera bound IgE to this protein by ELISA and dot blot | 1 | 2018-04-29 00:22:34 | 2024-06-06 13:09:15 | ||
| Animalia Arthropoda | Decapoda | Scylla paramamosain | Green mud crab | 1055 | Scy p 9 | Filamin C | 90 kDa | 30 of 100 subjects allergic to crustaceans had IgE binding to natural and recombinant protein by western blot, dot blot and ELISA | 32267266 | 1 | 2021-03-20 21:22:14 | 2024-12-04 17:27:03 | |
| Animalia Chordata | Perciformes | Sebastes marinus [S. norvegicus] | Ocean perch, redfish | 582 | Seb m 1 | Beta-parvalbumin | 11 kDa | 1 | 2009-12-30 12:00:00 | 2020-05-15 00:00:54 | |||
| Plantae Liliopsida (monocots) | Poales | Secale cereale | Rye | 755 | Sec c 1 | renamed to Sec c 38; designation reserved for beta-expansin pollen allergen | 2 | 2012-08-30 12:00:00 | 2019-09-24 07:16:10 | ||||
| Plantae Liliopsida (monocots) | Poales | Secale cereale | Rye | 729 | Sec c 5 | Group 5 grass pollen allergen | 30 kDa | 2 | 2011-05-25 12:00:00 | 2019-09-24 07:21:19 | |||
| Plantae Liliopsida (monocots) | Poales | Secale cereale | Rye | 584 | Sec c 20 | Gamma-secalin, coeliac immunoreactive protein | 70 kDa | In ELISA 21/23 (91%) patients with wheat-dependent, exercise-induced anaphylaxis showed IgE antibodies to purified gamma-70 secalin. Skin prick testing gave positive reactions to gamma-70 secalin in 10/15 (67%) patients - IgE binding to Gamma-70 coeliac immunoreactive protein on immunoblot using serum of a coeliac patient. | 11260160 | 1 | 2003-02-18 12:00:00 | 2025-08-25 16:50:19 | |
| Plantae Liliopsida (monocots) | Poales | Secale cereale | Rye | 583 | Sec c 38 | Dimeric alpha-amylase/trypsin inhibitor | 13.5 | Sec c 1 | Purified Sec c 38 provokes positive responses in 15 out of 21 baker asthma patients (71%) when skin prick tests were performed. IgE binding in vitro | 7750539 | 2 | 2003-02-18 12:00:00 | 2019-09-24 07:22:39 |
| Plantae Eudikotyledons | Lamiales | Sesamum indicum | Sesame | 585 | Ses i 1 | 2S albumin | 9 kDa | All ten sesame-allergic patients tested showed IgE binding to sesam antigens in immunoblot and had a positive skin prick test to sesame. The major, clinically most important allergen was the 9 kDa protein Ses i 1. This 9 kDa band identified by Pastorello et al. is the larger subunit of the 2S albumin. | 11419730 | 1 | 2003-04-07 12:00:00 | 2018-08-01 23:43:43 | |
| Plantae Eudikotyledons | Lamiales | Sesamum indicum | Sesame | 586 | Ses i 2 | 2S albumin | 7 kDa | Of 20 patients with sesam allergy tested, 30% showed IgE binding to Ses i 2 on immunoblot of sesam seed extract. | 12110835 | 1 | 2003-04-07 12:00:00 | 2019-09-24 07:31:07 | |
| Plantae Eudikotyledons | Lamiales | Sesamum indicum | Sesame | 587 | Ses i 3 | 7S vicilin-like globulin | 45 kDa | Of 20 patients with sesam allergy tested, 75% showed IgE binding to Ses i 3 on immunoblot of sesam seed extract. | 12110835 | 1 | 2003-04-10 12:00:00 | 2019-09-24 07:31:44 | |
| Plantae Eudikotyledons | Lamiales | Sesamum indicum | Sesame | 588 | Ses i 4 | oleosin | 17 kDa | 32/32 (100%) of sera from sesame allergic individuals contained IgE bound to oleosin by SDS-PAGE immunoblotting using purified sesame seed oil bodies. | 16436145 | 1 | 2006-06-08 12:00:00 | 2019-09-24 07:39:34 | |
| Plantae Eudikotyledons | Lamiales | Sesamum indicum | Sesame | 589 | Ses i 5 | oleosin | 15 kDa | 32/32 (100%) of sera from sesame allergic individuals contained IgE bound to oleosin by SDS-PAGE immunoblotting using purified sesame seed oil bodies. | 16436145 | 1 | 2006-06-08 12:00:00 | 2019-09-24 07:40:03 | |
| Plantae Eudikotyledons | Lamiales | Sesamum indicum | Sesame | 590 | Ses i 6 | 11S globulin | 52 kDa | 13 of 25 sesame seed allergic subjects had IgE binding to recombinant Ses i 6 by immunoblot | 17556061 | 1 | 2006-06-08 12:00:00 | 2019-09-24 07:40:44 | |
| Plantae Eudikotyledons | Lamiales | Sesamum indicum | Sesame | 591 | Ses i 7 | 11S globulin | 57 kDa | 10 of 24 sesame allergic subjects had IgE binding to recombinant Ses i 7 | 17556061 | 1 | 2007-02-08 12:00:00 | 2019-09-24 07:41:15 | |
| Plantae Eudikotyledons | Brassicales | Sinapis alba | Yellow mustard | 592 | Sin a 1 | 2S albumin | 14 kDa | All 11 mustard-sensitive patients tested showed IgE binding to purified Sin a 1 on immunoblot. | 7688955 | 1 | 2003-06-19 12:00:00 | 2019-09-24 07:42:46 | |
| Plantae Eudikotyledons | Brassicales | Sinapis alba | Yellow mustard | 593 | Sin a 2 | 11S globulin (legumin-like) seed storage protein | 51 kDa | 44% of 39 mustard-allergic patients positive in ELISA | 17349683 | 1 | 2008-01-28 12:00:00 | 2019-09-24 07:45:13 | |
| Plantae Eudikotyledons | Brassicales | Sinapis alba | Yellow mustard | 594 | Sin a 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 12.3 kDa | 1 | 2009-07-21 12:00:00 | 2025-04-10 18:25:38 | |||
| Plantae Eudikotyledons | Brassicales | Sinapis alba | Yellow mustard | 595 | Sin a 4 | Profilin | 13/14 kDa | 1 | 2009-07-21 12:00:00 | 2019-09-24 07:47:40 | |||
| Plantae Eudikotyledons | Solanales | Solanum lycopersicum (Lycopersicon esculentum) | Tomato | 422 | Sola l 1 | Profilin | 14 kDa | Lyc e 1 | Eleven out of 34 food-allergic patients (32%) display IgE binding to both purified profilins. Preincubation of a serum pool with either purified rCap a 2 or rSola l 1 nearly abolished IgE binding to natural Cap a 2 and Sola l 1, respectively. In addition, purified recombinant Cap a 2 was able to inhibit IgE-binding to rSola l 1 by approximately 50%, whereas rSola l 1 completely blocked IgE-binding to rCap a 2 in cross-inhibition assays. | 12915767 | 1 | 2003-08-08 12:00:00 | 2019-09-26 06:45:44 |
| Plantae Eudikotyledons | Solanales | Solanum lycopersicum (Lycopersicon esculentum) | Tomato | 423 | Sola l 2 | Beta-fructofuranosidase | 50 kDa | Lyc e 2 | In histamine release test, 4 of the 10 CCD-positive sera from patients with tomato allergy induced releases ranging from 12% to 82% with both natural Sola l 2 and recombinant Sola l 2 glycoproteins. | 12704374 | 1 | 2003-08-12 12:00:00 | 2019-09-26 06:48:01 |
| Plantae Eudikotyledons | Solanales | Solanum lycopersicum (Lycopersicon esculentum) | Tomato | 424 | Sola l 3 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | Lyc e 3 | Sera from 10 of 35 (29%) tomato-allergic patients (symptoms, sIgE > 0.35 kUA/L) showed IgE binding to a 9 kDa band in taomto peel extract identified as nsLTP1 by N-terminal sequencing. Cross-reactivity with Pru av 3 from cherry was shown by IgE immunoblot inhibition. | 17177799 | 1 | 2006-11-03 12:00:00 | 2024-03-08 14:48:12 |
| Plantae Eudikotyledons | Solanales | Solanum lycopersicum (Lycopersicon esculentum) | Tomato | 695 | Sola l 4 | Pathogenesis-related protein, PR-10, Bet v 1 family member, TSI-1 | 20 kDa | Lyc e 4 | ImmunoCAP data revealed prevalence of specific IgE to Sola l 4 in 76% of 42 birch pollen allergic patients with allergy to fresh tomato fruits. | 24510486 | 1 | 2013-06-04 12:00:00 | 2019-09-26 07:02:36 |
| Plantae Eudikotyledons | Solanales | Solanum lycopersicum (Lycopersicon esculentum) | Tomato | 783 | Sola l 5 | Cyclophilin | 19 kDa | 23762294 | 1 | 2013-11-05 12:00:00 | 2024-07-09 18:13:43 | ||
| Plantae Eudikotyledons | Solanales | Solanum lycopersicum (Lycopersicon esculentum) | Tomato | 821 | Sola l 6 | Non-specific lipid transfer protein type 2 (nsLTP2) | 7 kDa | The majority of 20 tomato allergic Italian subjects showed IgE binding to Sola l 6 by ISAC | 25791776, 26840232 | 1 | 2015-05-23 12:00:00 | 2024-06-28 17:47:08 | |
| Plantae Eudikotyledons | Solanales | Solanum lycopersicum (Lycopersicon esculentum) | Tomato | 832 | Sola l 7 | Non-specific lipid transfer protein type 1 (nsLTP1) | 12.5 kDa (SDS PAGE reducing) | 16 of 28 subjects with clinical history of allergy to tomato had IgE binding to natural, purified nsLTP1 by western blot and ELISA, 5 of 7 were SPT+ to pure protein and 5 of 7 positive by BAT. Congress presentation, XXXVII SEBBM, Granada Spain, 2014. Authors L. Martin-Pedraza, M. Gonzalez, JC Lopez-Rodriguez, E. Batanero, R Barderas, M Blanca, R Rodriguez, M Villalba | 26840232 | 1 | 2015-11-04 12:00:00 | 2025-04-10 18:10:00 | |
| Plantae Eudikotyledons | Solanales | Solanum melongena | Eggplant | 989 | Sola m 1 | Profilin | 17 kDa | 36 patients with oral allergy syndrome or more, were positive by SPT to extract of brinjal and were positive by IgE binding in ELISA to recombinant protein. 6 of 6 were positive by basophil activation at 1ug/ml natural allergen. | 31901836 | 1 | 2019-11-11 19:03:42 | 2025-08-25 19:27:31 | |
| Plantae Eudikotyledons | Solanales | Solanum tuberosum | Potato | 607 | Sola t 1 | Patatin | 43 kDa | In ELISA, 20 of 27 (74%) children with positive skin prick test responses to potato showed IgE binding to purified patatin. A positive wheal-and-flare reaction was seen in 8 of 14 children prick tested with purified patatin. - see also medline 21603273 | 9893201 | 1 | 2003-08-14 12:00:00 | 2019-09-26 07:10:25 | |
| Plantae Eudikotyledons | Solanales | Solanum tuberosum | Potato | 608 | Sola t 2 | Cathepsin D inhibitor PDI, aspartic protease inhibitor 11, Kunitz-type protease inhibitor | 21 kDa | 20 out of 39 (51%) sera of children with positive skin prick test (SPT) to raw potato showed IgE binding to purified Sola t 2 in ELISA. Of 8 children tested, 3 gave a positive response to Sol t 2 (20 ug/ml) in skin prick test. | 11421919 | 1 | 2003-08-14 12:00:00 | 2025-08-25 16:55:32 | |
| Plantae Eudikotyledons | Solanales | Solanum tuberosum | Potato | 609 | Sola t 3 | Cysteine protease inhibitor 1, cysteine protease inhibitor 10, Kunitz-type protease inhibitor | 21 kDa | Of 39 children with positive skin prick test (SPT) to raw potato, 23 (58%)showed IgE binding to purified Sola t 3 in ELISA. Of 8 children tested, 5 gave a positive response to Sol t 3 (40 ug/ml) in skin prick test. | 11421919 | 1 | 2003-08-14 12:00:00 | 2025-08-25 16:57:05 | |
| Plantae Eudikotyledons | Solanales | Solanum tuberosum | Potato | 610 | Sola t 4 | Serine protease inhibitor 7, Kunitz-type protease inhibitor, PIG | 16 kDa | Of 39 children with positive skin prick test (SPT) to raw potato, 26 (67%)showed IgE binding to purified Sola t 4 in ELISA. Of 8 children tested, 4 gave a positive response to Sol t 4 (20 ug/ml) in skin prick test. | 11421919 | 1 | 2003-08-14 12:00:00 | 2025-08-25 16:55:56 | |
| Animalia Chordata | Pleuronectiformes | Solea solea | Sole | 1071 | Sole s 1 | Parvalbumin | 11-14 kDa | Twenty seven of 29 subjects with reported allergy to fish were positive by IgE binding ELISA to purified parvalbumin from sole. | 1 | 2021-08-24 03:08:48 | 2024-12-04 17:41:16 | ||
| Animalia Arthropoda | Hymenoptera | Solenopsis geminata | Tropical fire ant | 596 | Sol g 2 | 13 kDa | 4 | 2003-06-03 12:00:00 | 2019-09-26 01:32:20 | ||||
| Animalia Arthropoda | Hymenoptera | Solenopsis geminata | Tropical fire ant | 597 | Sol g 3 | 24 kDa | 4 | 2003-06-03 12:00:00 | 2019-09-26 01:33:38 | ||||
| Animalia Arthropoda | Hymenoptera | Solenopsis geminata | Tropical fire ant | 598 | Sol g 4 | 12 kDa | 11790727 | 4 | 2003-06-03 12:00:00 | 2020-03-16 19:37:11 | |||
| Animalia Arthropoda | Hymenoptera | Solenopsis invicta | Red imported fire ant | 599 | Sol i 1 | Phospholipase A1B | 18 kDa | Of 23 S.invicta-allergic patients, 20 showed IgE binding to purified Sol i 1 in RAST. - All 6 patients sensitive to fire ants showed IgE binding to purified Sol i 1 in RAST: medline 98049167. | 3192865 | 4 | 2003-06-03 12:00:00 | 2019-09-26 01:47:59 | |
| Animalia Arthropoda | Hymenoptera | Solenopsis invicta | Red imported fire ant | 600 | Sol i 2 | 14 kDa | Of 23 S.invicta-allergic patients, 14 (61%) showed IgE binding to purified Sol i 2 in RAST - Of 6 patients sensitive to fire ants, only 1 showed significant IgE binding to Sol i 2 in RAST; another 3 patients were marginally reactive. | 3192865 | 4 | 2003-06-03 12:00:00 | 2020-03-23 20:13:16 | ||
| Animalia Arthropoda | Hymenoptera | Solenopsis invicta | Red imported fire ant | 601 | Sol i 3 | 26 kDa | Of 6 patients sensitive to fire ants, 4 showed significant IgE binding to Sol i 3 in RAST - Of 23 S.invicta-allergic patients, 14 (61%) showed IgE binding to purified Sol i 3 in RAST. | 9389299 | 4 | 2003-06-03 12:00:00 | 2020-03-23 20:22:27 | ||
| Animalia Arthropoda | Hymenoptera | Solenopsis invicta | Red imported fire ant | 602 | Sol i 4 | 12 kDa | Of 6 fire ant-sensitive patients, 4 showed significant IgE binding to Sol i 4 in RAST. - Of 23 S.invicta-allergic patients, 17 (74%) showed IgE binding to purified Sol i 4 in RAST. | 9389299 | 4 | 2003-06-11 12:00:00 | 2020-03-23 20:24:07 | ||
| Animalia Arthropoda | Hymenoptera | Solenopsis richteri | Black fire ant | 603 | Sol r 2 | 13 kDa | IgE binding to purified Sol r 2 in RAST | 2355158 | 4 | 2003-06-11 12:00:00 | 2019-09-26 01:56:35 | ||
| Animalia Arthropoda | Hymenoptera | Solenopsis richteri | Black fire ant | 604 | Sol r 3 | 24 kDa | IgE binding to purified Sol r 3 in RAST | 2355158 | 4 | 2003-06-11 12:00:00 | 2019-09-26 01:57:33 | ||
| Animalia Arthropoda | Hymenoptera | Solenopsis saevissima | Brazilian fire ant | 605 | Sol s 2 | 13 kDa | Solenopsis saevissima is the most common fire ant species in Brazil and a common cause of allergic sting reactions there. Patient sera from Brazil are reactive with Solenopsis invicta allergens (Hoffman DR, unpublished). Sol s venom could not be obtained to evaluate. | 4 | 2003-06-11 12:00:00 | 2019-09-26 06:43:45 | |||
| Animalia Arthropoda | Hymenoptera | Solenopsis saevissima | Brazilian fire ant | 606 | Sol s 3 | 24 kDa | Solenopsis saevissima is the most common fire ant species in Brazil and a common cause of allergic sting reactions there. Patient sera from Brazil are reactive with Solenopsis invicta allergens (Hoffman DR, unpublished). Sol s venom could not be obtained to evaluate. | 4 | 2003-06-11 12:00:00 | 2019-09-26 06:44:38 | |||
| Plantae Liliopsida (monocots) | Poales | Sorghum halepense | Johnson grass | 611 | Sor h 1 | Beta-expansin | 30-35 kDa | Sor h 1 is recognized on immunoblots of Johnson grass extract by Mabs raised against Cyn d 1 and by IgE from pooled sera of individuals allergic to Bermuda grass. When tested with 64 grass pollen-allergic patients from a subtropical region, 49 showed IgE reactivity with purified Sor h 1 in ELISA. Of 49 patients with positive SPT to Johnson grass, 97% showed IgE reactivity with Sor h 1 in ELISA. | 25129679 | 2 | 2003-03-06 12:00:00 | 2019-09-26 07:12:23 | |
| Plantae Liliopsida (monocots) | Poales | Sorghum halepense | Johnson grass | 852 | Sor h 2 | Expansin-like protein; grass pollen group 2 allergen | 12 kDa | 11 of 11 patients with Johnson grass pollen sensitivity by SPT showed serum IgE reactivity by immunoblotting with whole Johnson grass pollen extract with a band identified as Sor h 2. Sera pooled from six of these patients showed IgE reactivity with a protein spot on 2D immunoblot matching this sequence identified by mass spectrometery of a protein excised from a replica gel. | 25129679 | 2 | 2015-11-10 12:00:00 | 2019-09-26 07:14:05 | |
| Plantae Liliopsida (monocots) | Poales | Sorghum halepense | Johnson grass | 793 | Sor h 13 | Exopolygalacturonase (Glycosyl hydrolase 28) | 54-55 kDa (glycosylated protein) | Sera from 28 of 64 patients with allergic rhinitis and allergic sensitivity to various grass pollen reacted with the purified natural Sor h 13. Sor h 13 comprises two isoforms, Sor h 13.0101 and Sor h 13.0201 (86% amino acid sequence identity) as shown by mass spectrometry and by total transcriptome sequencing. | 2 | 2014-04-24 12:00:00 | 2019-09-26 07:15:50 | ||
| Fungi Ascomycota | Hypocreales | Stachybotrys chartarum | Black mold | 722 | Sta c 3 | Extracellular alkaline Mg-dependent exodesoxyribonuclease | 21 kDa (Glycosylated monomer) | 5 of 6 S. chartarum allergic patients (preselected population) had IgE that reacted with purified Sta c 3 in ELISA. | 2 | 2011-04-07 12:00:00 | 2019-09-26 07:22:59 | ||
| Animalia Arthropoda | Sarcoptiformes | Suidasia pontifica | Scaly mite | 1187 | Sui p 2 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 14 kDa | 100 allergic patients with mite allergy were diagnosed with standardized questionnaires (allergic rhinitis, asthma or atopic dermatitis combined with typical mite-associated symptom exacerbation). Of those, 82 has specific IgE to Suidasia pontifica extract (by ELISA). Of the sera from Sui p sensitized patients, 40 (49%) had IgE to recombinant Sui p 2.0101, while only 1 of 100 non-allergic donors' sera has Sui p 2-specific IgE. In an inhibition ELISA, IgE binding to Sui p extract was inhibited by rSui p 2 by > 50% with 4 of 6 Sui p 2-positive sera. | 2 | 2026-03-03 17:03:21 | 2026-03-03 17:03:21 | ||
| Animalia Chordata | Cetartiodactyla | Sus scrofa | Domestic pig | 854 | Sus s 1 | Serum albumin | 60 kDa | 37 patients sensitized to cat, n=5 had IgE to Fel d 2 with n=1 having cross-reactive IgE to porcine SA (Sus s 1); 39 highly sensitized cat-allergic, n=9 had IgE to Fel d 2, all 9 had cross-reactive IgE to porcine SA (Sus s 1); 3 patients with pork-cat syndrome, all 3 had cross-reactive IgE to porcine SA (Sus s 1) | 9105522,23352634 | 1 | 2015-11-30 12:00:00 | 2019-09-26 07:24:52 | |
| Plantae Eudikotyledons | Lamiales | Syringa vulgaris | Lilac | 612 | Syr v 1 | Ole e 1-related protein | 20 kDa | 9 out of 10 sera from olive-allergic patients tested, showed IgE binding to rSyr v 1 on immunoblot. | 11251633, 8319129 | 2 | 2003-04-07 12:00:00 | 2019-09-26 07:29:14 | |
| Plantae Eudikotyledons | Lamiales | Syringa vulgaris | Lilac | 613 | Syr v 3 | Polcalcin | 8.9 kDa theoretical mass | 2 | 2003-04-07 12:00:00 | 2019-09-26 07:47:54 | |||
| Animalia Arthropoda | Diptera | Tabanus yao | Horsefly | 713 | Tab y 1 | Apyrase | 70 kDa | 30 of 37 horsefly allergic individuals had IgE that reacted with purified natural Tab y 1 in Western blots. 6 of 6 horsefly allergic individuals had a positive skin prick test when tested with purified natural Tab y 1. 6 of 6 horsefly allergic individuals had a positive basophil activation test when assayed with purified natural Tab y 1. | 21848516 | 4 | 2011-03-30 12:00:00 | 2020-03-16 19:46:55 | |
| Animalia Arthropoda | Diptera | Tabanus yao | Horsefly | 704 | Tab y 2 | Hyaluronidase | 35 kDa | 34 of 37 horsefly allergic subjects had IgE that reacted with the natural Tab y 2 in immunoblots. | 20608917 | 4 | 2010-10-18 12:00:00 | 2020-03-23 21:03:18 | |
| Animalia Arthropoda | Diptera | Tabanus yao | Horsefly | 705 | Tab y 5 | Antigen 5-related protein, CAP (cysteine-rich secretory proteins, antigen 5 and pathogenesis-related 1) protein superfamily member | 26 kDa | 32 of 37 horsefly allergic subjects had IgE that reacted with Tab y 5 in immunoblots. | 20608917 | 4 | 2010-10-18 12:00:00 | 2020-03-23 21:14:02 | |
| Animalia Arthropoda | Lepidoptera | Thaumetopoea pityocampa | Pine processionary moth | 614 | Tha p 1 | 15 kDa | The clinical relevance of this allergen was measured using sera from patients allergic to caterpillar. RESULTS: An allergen with a molecular weight close to 15 kDa was purified. It was recognized by 9 out of 11 allergic patients (82%). | 12580804 | 3 | 2006-11-05 12:00:00 | 2019-09-26 08:04:36 | ||
| Animalia Arthropoda | Lepidoptera | Thaumetopoea pityocampa | Pine processionary moth | 668 | Tha p 2 | Protein with unknown function | 15 kDa | 11 of 18 individuals allergic to the pine processionary caterpillar had IgE that bound to the purified natural Tha p 2 in IgE immunoblot. | 22708991 | 3 | 2010-02-11 12:00:00 | 2019-09-26 08:05:44 | |
| Animalia Chordata | Perciformes | Thunnus albacares | Yellowfin tuna | 615 | Thu a 1 | Beta-parvalbumin | 11 kDa | 37/62 (60%) fish-allergic patients had IgE reacting to purified natural Thu a 1. | 23786287 | 1 | 2009-12-30 12:00:00 | 2020-05-15 00:02:28 | |
| Animalia Chordata | Perciformes | Thunnus albacares | Yellowfin tuna | 751 | Thu a 2 | Beta-enolase | 50 kDa | Sera of 12 of 62 fish allergic individuals had IgE that reacted with the purified natural Thu a 2 in ELISA. IgE of 1 of 2 tested patients produced a postitive RBL assay with Thu a 2. | 23786287 | 1 | 2012-07-30 12:00:00 | 2020-05-15 00:04:18 | |
| Animalia Chordata | Perciformes | Thunnus albacares | Yellowfin tuna | 752 | Thu a 3 | Aldolase A | 40 kDa | Sera of 8 of 62 (13%) fish allergic patients had IgE that reacted with purified natural Thu a 3 in ELISA. IgE of 2 of 2 tested patients produced postive RBL assays with Thu a 3. | 23786287 | 1 | 2012-07-30 12:00:00 | 2020-05-15 00:05:58 | |
| Animalia Mollusca | Teuthida | Todarodes pacificus | Japanese flying squid | 616 | Tod p 1 | Tropomyosin | 38 kDa | All 11 patients tested (selection based on squid and/or shrimp-sensitivity), showed IgE binding to purified Tod p 1 in ELISA. | 8939158 | 1 | 2003-07-03 12:00:00 | 2019-09-26 08:17:35 | |
| Animalia Arthropoda | Hemiptera | Triatoma protracta | California kissing bug | 631 | Tria p 1 | Procalin | 20 kDa | 11509613 | 4 | 2006-11-05 12:00:00 | 2019-09-27 08:41:38 | ||
| Animalia Chordata | Scombriformes | Trichiurus lepturus | Atlantic cutlass, largehead hairtail | 1141 | Tric l 1 | Parvalbumin | 11 kGa | Sera from 9 fish-allergic patients with symptoms to multiple fish species and fish-specific IgE as determined by commercial ImmunoCAP to various fish extracts were tested. All sera had IgE to recombinant Tric l 1.0101 (expressed in E.coli) and partially purified natural cutlass parvalbumin in an ELISA. Recombinant and natural parvalbumins were able to inhibit IgE binding to cutlass extract by 30% and 59%, respectively. | 42223044 | 1 | 2023-12-18 12:32:18 | 2026-06-10 12:40:25 | |
| Fungi Ascomycota | Onygenales | Trichophyton rubrum | Athlete's foot fungus | 627 | Tri r 2 | Putative secreted alkaline protease Alp1 | 29 kDa | Specific IgE Ab were measured in 73 sera: the prevalence of IgE Ab was significantly higher among subjects with IH skin test reactions (43%) compared with those with DTH or negative skin test reactions (12%). Five of nine individuals with delayed reactions to the Trichophyton mixture showed a positive delayed type hypersensitivity reaction in response to rTri r 2 maximal at 24 h | 9792655, 15653817 | 3 | 2003-08-31 12:00:00 | 2019-09-27 08:34:32 | |
| Fungi Ascomycota | Onygenales | Trichophyton rubrum | Athlete's foot fungus | 628 | Tri r 4 | Serine protease | 85 kDa | Preliminary results suggested that rTri r 4 exhibits partial loss of B cell epitopes, and that recombinant Tri r 4 failed to elicit DTH skin test responses in three individuals with DTH responses to natural Tri t 4. | 9792655, 15653817 | 3 | 2003-08-31 12:00:00 | 2019-09-27 08:36:59 | |
| Fungi Ascomycota | Onygenales | Trichophyton tonsurans | Ringworm fungus | 629 | Tri t 1 | 30 kDa | Of 48 Trichophyton-sensitized patients with a positive skin test to Trichophyton extract, 26 (54%) showed serum IgE binding to purified 125I-Tri t 1 in antigen binding assay. Of the patients who also had a positive Trichophyton RAST, 73% showed IgE binding to 125I-Tri t 1. Purified Tri t 1 induced a immediate skin response in 8 out of 9 Trichophyton-sensitized patients tested. | 1711086 | 3 | 2003-09-01 12:00:00 | 2019-09-27 08:39:29 | ||
| Fungi Ascomycota | Onygenales | Trichophyton tonsurans | Ringworm fungus | 630 | Tri t 4 | Serine protease | 83 kDa | Of 8 patients with a delayed (DH) skin test response to Trichophyton extract, 5 had a DH response to purified Tri t 4. These patients did not have detectable IgE to Tri t 4. Of 9 patients with an immediate (IH) skin test response to Trichophyton extract, 6 had a IH response to Tri t 4. 4 of those 9 patients showed IgE binding to Tri t 4 in RAST. | 8568277 | 3 | 2003-09-01 12:00:00 | 2024-07-11 12:51:30 | |
| Plantae Eudikotyledons | Malvales | Triplochiton scleroxylon | Obeche | 806 | Trip s 1 | Endochitinase | 38 kDa | Seven of 10 occupationally affected wood-workers had IgE binding to Trip s 1 by reducing immunoblot, 32 of 40 by ImmunoCAP | 15876312, 18956126, 14763938 | 2 | 2016-02-23 12:00:00 | 2019-09-27 08:43:40 | |
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 617 | Tri a 12 | Profilin | 14 kDa | 1 | 2003-03-25 12:00:00 | 2019-09-27 07:58:11 | |||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 618 | Tri a 14 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | Specific IgE to Tri a 14.0101, purified from wheat, was found in 60% of 40 sera from patients with baker's asthma, and the purified allergen elicited positive skin prick test reactions in 62% of 24 of these patients (Palacin et al. 2007; PubMed: 17716720). In a different study, one subject with baker's asthma out of 40 had IgE binding to rTri a 14.0201 - maltose binding protein at ~ 1 kU/L, and 1 of 10 control subjects had equivalent IgE binding by ImmunoCap (Sander et al. 2011; PubMed: 21557753). | 17716720, 21557753 | 2 | 2007-02-18 12:00:00 | 2025-04-10 18:10:41 | |
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 714 | Tri a 15 | Monomeric alpha-amylase inhibitor 0.28 | Four out of 40 subjects with baker's asthma had IgE binding to rTri a 15. | 21557753 | 2 | 2011-04-07 12:00:00 | 2019-09-27 07:37:24 | ||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 937 | Tri a 17 | beta-amylase | 56 kDa | Tri a bA | Seven of 17 subjects with apparent food allergy to wheat had IgE binding to recombinant beta amylase that was made based on a cDNA clone. Two of two were positive by basophil activation using humanized RBL assay. Non-allergic subjects were negative. | 1 | 2018-09-10 18:14:51 | 2019-09-27 07:40:12 | |
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 619 | Tri a 18 | Agglutinin isolectin 1, isolectin A, wheat germ agglutinin 1 (WGA1) | Wheat germ agglutinin (a fraction purified using a concanavalin-A affinity column) was identified as allergen for some but not all of the allergic bakers (sera from 35 individuals with suspected allergies to inhaled flour were tested). | 6697476 | 1 | 2003-03-06 12:00:00 | 2025-08-25 16:51:55 | ||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 620 | Tri a 19 | Omega-5 gliadin | 65 kDa | All 27 patients with wheat-dependent, exercise-induced anaphylaxis had IgE antibodies against purified Tri a 19 (ELISA). - Purified Tri a 19 released significantly (pLESSTHAN0.001) more histamine from basophils of patients (n=9; 47.6% release) than from controls (n=5; 4.5% release) - All 15 patients tested had positive skin prick test responses to gamma-gliadin also | 12534555 | 1 | 2003-03-06 12:00:00 | 2023-09-19 14:17:08 | |
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 796 | Tri a 20 | Gamma gliadin | 35 to 38 kDa | see isoallegen records | 23963475,37473737 | 1 | 2014-07-02 12:00:00 | 2023-09-21 19:11:21 | |
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 715 | Tri a 21 | Alpha/beta gliadin | See isoallergen records | 21557753,37473737 | 2 | 2011-04-07 12:00:00 | 2024-07-09 18:15:51 | ||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 621 | Tri a 25 | Thioredoxin | 16522470 | 1 | 2006-10-13 12:00:00 | 2019-09-27 07:50:55 | |||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 622 | Tri a 26 | High molecular weight glutenin | 88 kDa | 1 | 2006-10-13 12:00:00 | 2019-09-27 07:52:18 | |||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 623 | Tri a 27 | Thiol reductase homologue | 27 kDa | Tri a Bd 27K | Bakers asthma 6 of 38 subjects with Baker's asthma had IgE binding by ELISA with rTri a 27.0101 fusion ptn | 21557753 | 2 | 2009-10-15 12:00:00 | 2021-12-12 23:00:52 |
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 624 | Tri a 28 | Dimeric alpha-amylase inhibitor 0.19 | 13 kDa | 10 of 40 subjects with baker's asthma had IgE binding to rTri a 28 fusion protein (maltose binding protein), based on ImmunoCap. Zero of 10 controls bound IgE | 21557753 | 2 | 2009-10-15 12:00:00 | 2021-12-12 23:04:57 | |
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 625 | Tri a 29 | Tetrameric alpha-amylase inhibitor CM1/CM2 | 13 kDa | 21557753 | 2 | 2009-10-15 12:00:00 | 2020-05-12 23:54:36 | ||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 626 | Tri a 30 | Tetrameric alpha-amylase inhibitor CM3 | 16 kDa | 21557753 | 2 | 2009-10-15 12:00:00 | 2020-05-12 23:55:32 | ||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 716 | Tri a 31 | Triosephosphate-isomerase | 21557753 | 2 | 2011-04-07 12:00:00 | 2020-05-12 23:56:23 | |||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 717 | Tri a 32 | 1-cys-peroxiredoxin | 21557753 | 2 | 2011-04-07 12:00:00 | 2020-05-12 23:56:57 | |||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 718 | Tri a 33 | Serpin | 21557753 | 2 | 2011-04-07 12:00:00 | 2020-05-12 23:57:29 | |||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 719 | Tri a 34 | Glyceraldehyde-3-phosphate-dehydrogenase | Two of 40 subjects with bakers asthma had IgE binding using a fusion protein of rTri a 34 and maltose binding protein by ImmunoCap. | 21557753 | 2 | 2011-04-07 12:00:00 | 2020-05-12 23:50:25 | ||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 720 | Tri a 35 | Dehydrin | 2 of 38 subjects with baker's asthma had IgE binding to dehydrin, rTri a 35-maltose binding fusion protein by ImmunoCap. | 21557753 | 2 | 2011-04-07 12:00:00 | 2024-07-09 18:16:50 | ||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 728 | Tri a 36 | Low molecular weight glutenin | 40 kDa | see isoallergen records | 22904302,37473737 | 1 | 2011-05-23 12:00:00 | 2023-09-21 18:13:32 | |
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 734 | Tri a 37 | Alpha purothionin | 12 kDa | 1 | 2011-11-08 12:00:00 | 2019-09-27 08:07:46 | |||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 769 | Tri a 39 | Serine protease inhibitor-like protein | 18 of 101 European bakers (Spain, Netherlands and Germany), had IgE binding to recombinant Tri a 39 in Immunocap. | 25576081 | 2 | 2013-01-09 12:00:00 | 2024-07-09 18:18:12 | ||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 840 | Tri a 40 | Tetrameric alpha-amylase inhibitor CM17 | 15.96 kDa | 8 out of 94 test subjects tested positive for in vitro IgE binding using ImmunoCAP. | 26846378 | 2 | 2015-08-07 12:00:00 | 2023-09-19 14:15:03 | |
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 845 | Tri a 41 | Mitochondrial ubiquitin ligase activator of NFKB 1 (fragment) | 151 patients with baker's asthma were tested. Symptoms were confirmed by sIgE to wheat (ImmunoCAP) and specific inhalation challenge with wheat flour in ambiguous cases. Of those, 7 sera (5%) reacted in an IgE ELISA with recombinant Tri a 41.0101 produced in E. coli. | 26100087 | 2 | 2015-09-23 12:00:00 | 2023-09-21 15:38:53 | ||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 846 | Tri a 42 | Tapetum determinant 1 (TPD1) fragment | 151 patients with baker's asthma were tested. Symptoms were confirmed by sIgE to wheat (ImmunoCAP) and specific inhalation challenge with wheat flour in ambiguous cases. Of those, 20 sera (13%) reacted in an IgE ELISA with recombinant Tri a 42.0101 produced in E. coli. | 26100087 | 2 | 2015-10-05 12:00:00 | 2023-09-21 16:16:48 | ||
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 847 | Tri a 43 | Transcriptional corepressor SCAI | 12 kDa | 151 patients with baker's asthma were tested. Symptoms were confirmed by sIgE to wheat (ImmunoCAP) and specific inhalation challenge with wheat flour in ambiguous cases. Of those, 19 sera (13%) reacted in an IgE ELISA with recombinant Tri a 43.0101 produced in E. coli. | 26100087 | 2 | 2015-10-05 12:00:00 | 2023-09-21 15:31:20 | |
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 848 | Tri a 44 | Endosperm transfer cell specific PR60 (nsLTP-like protein) | 10 kDa | 151 patients with baker's asthma were tested. Symptoms were confirmed by sIgE to wheat (ImmunoCAP) and specific inhalation challenge with wheat flour in ambiguous cases. Of those, 6 sera (4%) reacted in an IgE ELISA with recombinant Tri a 44.0101 produced in E. coli. | 26100087 | 2 | 2015-09-23 12:00:00 | 2023-09-21 15:23:52 | |
| Plantae Liliopsida (monocots) | Poales | Triticum aestivum | Wheat | 849 | Tri a 45 | Transcription elongation factor 1 (EIF1) | 10 kDa | 151 patients with baker's asthma were tested. Symptoms were confirmed by sIgE to wheat (ImmunoCAP) and specific inhalation challenge with wheat flour in ambiguous cases. Of those, 20 sera (13%) reacted in an IgE ELISA with recombinant Tri a 45.0101 produced in E. coli. | 26100087 | 2 | 2015-09-23 12:00:00 | 2023-09-21 15:23:18 | |
| Plantae Liliopsida (monocots) | Poales | Triticum turgidum ssp durum | Durum wheat | 915 | Tri tu 14 | nsLipid transfer protein 1 | 9.2 kDa | 23 of 32 subjects with bakers asthma or wheat food allergy had positive IgE to recombinant non-specific Lipid Transfer Protein of durum wheat. This was presented as a poster at the 7th ISMA conference in Luxembourg | 30199586 | 1 | 2017-12-22 03:47:56 | 2019-09-27 08:40:36 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 1017 | Tyr p 1 | Cysteine protease | 25 kDa | 298 subjects attending the Taichung Veterans General Hospital were recruited with at least asthma, rhinitis, atopic dermatitis or eczema. They were tested by SPT to recombinant protein. IgE binding tested by ELISA to recombinant protein, cloned by PCR. Indirect basophil activation was tested. 65 of 298 were positive by ELISA, 60 of 106 were positive by SPT and 35 of 30 positive by Basophil activation. | 32887361 | 2 | 2020-09-08 18:04:38 | 2020-09-08 18:05:04 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 634 | Tyr p 2 | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein | 16 kDa | A 16 kDa component of T. putrescentiae was recognized on immunoblot by serum IgE in 23/29 sera from mite-allergic patients. - rTyr p 2 reacted on immunoblot with IgE in a serumpool of 5 patients with T.putrescentiae positive RAST: medline 98151280 | 7982124 | 2 | 2003-05-13 12:00:00 | 2023-11-09 13:30:36 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 711 | Tyr p 3 | Trypsin | 26 kDa | 720 of 2400 mite allergic individuals had IgE that bound in ELISA to the purified natural Tyr p 3. | 19339798 | 2 | 2011-02-10 12:00:00 | 2019-09-27 08:53:07 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 1094 | Tyr p 4 | Alpha-amylase | 58 kDa | Five of 30 subjects had IgE binding above background to the recombinant protein, Tyr p 4. The claimed purity was 75%. | 2 | 2022-04-07 22:10:47 | 2022-04-12 12:27:18 | ||
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 1018 | Tyr p 7 | Bactericidal permeability increasing protein | 25 kDa | 298 subjects attending the Taichung Veterans General Hospital were recruited with at least asthma, rhinitis, atopic dermatitis or eczema. They were tested by SPT to recombinant protein. IgE binding tested by ELISA to recombinant protein, cloned by PCR. Indirect basophil activation was tested. 40 of 298 were positive in IgE binding by ELISA, 38 of 106 were positive by SPT and 22 of 28 were positive by Basophil activation. | 32887361 | 2 | 2020-09-08 19:47:47 | 2020-09-08 22:20:35 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 1000 | Tyr p 8 | Glutathione S transferase | 26 kDa | Ten Storage Mite allergic subjects in Taiwan were used to test IgE binding to Tyrophagus putrescentiae proteins by ELISA and immunoblot. Then ten were used in histamine release assay. There was very good release by the ten. And there was very high cross-reactivity to Dermatophagoides glutathione S transferase Der f 8, Der p 8. | 23365207 | 2 | 2020-01-20 19:29:34 | 2020-01-20 19:43:23 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 632 | Tyr p 10 | Tropomyosin | 33 kDa | rTyr 10 was recognized by IgE from 5/40 (12.5%) storage mite-sensitized and house dust mite-sensitized subjects in ELISA. | 17584167 | 2 | 2008-08-21 12:00:00 | 2019-09-27 08:49:37 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 1073 | Tyr p 11 | Paramyosin | 98 kDa non-reducing | 11 Subjects with asthma were positive by SPT with extract and by UniCAP to extract. Eight of the 11 were positive in western blot to the recombinant protein. Four non asthmatics were negative. | 36695039 | 2 | 2021-09-15 22:34:43 | 2025-04-30 13:18:38 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 633 | Tyr p 13 | Cytosolic fatty acid-binding protein | 15 kDa | 15879018 | 2 | 2006-11-05 12:00:00 | 2023-11-09 14:07:55 | ||
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 1019 | Tyr p 20 | Arginine kinase | 40 kDa | 298 subjects attending the Taichung Veterans General Hospital were recruited with at least asthma, rhinitis, atopic dermatitis or eczema. They were tested by SPT and ELISA to recombinant Tyr p 20.0101, which had been cloned by PCR. Indirect basophil activation was tested. 51 of 298 were positive for IgE binding by ELISA, 45 of 106 were positive by SPT and 25 of 30 positive by basophil activation. | 32887361 | 2 | 2020-09-08 22:39:58 | 2022-04-13 16:29:32 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 872 | Tyr p 28 | Heat shock protein Hsp70 | 76 kDa | Eight of 17 dust mite allergic subjects with IgE binding to E. coli synthesized recombinant protein | 27496383 | 2 | 2016-05-31 12:00:00 | 2023-11-22 18:11:57 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 1121 | Tyr p 31 | Cofilin | 17 kDa | Of 11 mite allergic patients' sera (symptoms, SPT and UniCAP to Tyr p), 8 (73%) showed IgE binding to rTyr p 31.0101 in Western blot. In addition, 29 mite-allergic pediatric patients (positive UniCAP to Der p and Der f) were tested by ELISA for IgE to rTyr p 31.0101. Of those 11 (38%) showed a positive signal. | 38143053 | 2 | 2022-11-02 17:19:04 | 2025-04-30 13:07:34 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 1075 | Tyr p 32 | Inorganic pyrophosphatase | 33 kDa | 11 asthmatic subjects were positive in SPT and ImmunoCAP to Tyrophagus putrescentiae extract and 8 were positive in IgE western blot with the recombinant protein, produced in E. coli. | 39710472 | 2 | 2021-09-15 23:02:20 | 2025-04-30 13:25:44 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 635 | Tyr p 34 | Troponin C | 18 kDa | Tyr p 24 | Sera of 5/47 (10.6%)of the tested patients had IgE that reacted with the recombinant Tyr p 24.0101 in ELISA.The diagnosis of teh patients was based on case history and skin prick testing. All 47 patients had IgE against T. putrescentiea extract as confirmed by ImmunoCAP. 22 subjects suffered from rhinitis, 14 from asthma, 1 from dizziness, 1 from bronchitis, and 1 from hypereosinophilia. | 19786801 | 2 | 2009-02-26 12:00:00 | 2019-09-27 08:54:51 |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 873 | Tyr p 35 | Aldehyde dehydrogenase | 52 kDa | 14 of 17 subjects with allergy to HDM had IgE binding to E. coli produced Tyr p 35 | 27496383 | 2 | 2016-06-01 12:00:00 | 2019-09-27 08:56:03 | |
| Animalia Arthropoda | Sarcoptiformes | Tyrophagus putrescentiae | Mold mite, cheese mite | 874 | Tyr p 36 | Profilin | 14 kDa | 12 of 17 airway, HDM allergic subjects had IgE to this protein by western blots | 27496383 | 2 | 2016-06-01 12:00:00 | 2019-09-27 08:56:37 | |
| Fungi Ascomycota | Pleosporales | Ulocladium chartarum (Alternaria chartarum) | Black mold | 946 | Ulo c 1 | Alt a 1 homologue | 17 kDa | Patient recall exposure and allergic responses, serum IgE tests with positive IgE by ELISA in 44 of 57 subjects who were positive in western blot and RAST or EAST and negative in 2 control subjects using recombinant protein from PCR of cDNA. Described in Congress abstract EAACI Allergy School on Aerobiology and Pollution. | 2 | 2018-11-02 16:20:18 | 2024-09-16 19:14:06 | ||
| Plantae Liliopsida (monocots) | Poales | Urochloa mutica | Para grass | 935 | Uro m 1 | Beta expansin | 30 kDa | Six subjects with airway allergic rhinitis to grass pollen were tested by SPT with extract and their sera was used in IgE binding studies with recombinant proteins of Beta expansins. Subjects were tested as per Pacharn et al 2018 PMID 29549697. Asian Pacific J Allergy Immunol. Six of six AR patients were positive by western blot and ELISA. One non-allergic subject's sera was negative. | 30983309 | 2 | 2018-08-17 16:46:01 | 2020-05-11 14:30:30 | |
| Animalia Arthropoda | Hymenoptera | Vespa crabro | European hornet | 649 | Vesp c 1 | Phospholipase A1B | 34 kDa | 4 | 2003-06-11 12:00:00 | 2019-09-06 20:42:47 | |||
| Animalia Arthropoda | Hymenoptera | Vespa crabro | European hornet | 650 | Vesp c 5 | Antigen 5 | 23 kDa | no information found | 4 | 2003-06-11 12:00:00 | 2019-09-06 20:43:03 | ||
| Animalia Arthropoda | Hymenoptera | Vespa magnifica | Hornet | 730 | Vesp ma 2 | Hyaluronidase | 35 kDa | 31 of 33 hornet venom allergic patients had IgE that reacted with the purified natural Vesp ma 2 in immunoblots. 9 of 15 hornet venom allergic patients reacted with a postive skin prick test to natural purified Vesp ma 2. | 22384100 | 4 | 2011-07-22 12:00:00 | 2020-05-11 12:31:45 | |
| Animalia Arthropoda | Hymenoptera | Vespa magnifica | Hornet | 732 | Vesp ma 5 | Antigen 5, member of PR-1 family | 25 kDa | 30 of 33 hornet venom allergic individuals had IgE that reacted with natural purified Vesp ma 5 in immunoblots. 11 of 15 hornet venom allergic individuals had positive reactions to skin prick tests with the natural purified Vesp ma 5. | 22384100 | 4 | 2011-07-22 12:00:00 | 2020-05-11 12:34:34 | |
| Animalia Arthropoda | Hymenoptera | Vespa mandarinia | Asian giant hornet | 651 | Vesp m 1 | Phospholipase A1B | 34 kDa | 4 | 2003-06-11 12:00:00 | 2019-09-06 20:43:29 | |||
| Animalia Arthropoda | Hymenoptera | Vespa mandarinia | Asian giant hornet | 652 | Vesp m 5 | Antigen 5 | 23 kDa | no information found | 4 | 2003-06-11 12:00:00 | 2019-09-06 20:45:16 | ||
| Animalia Arthropoda | Hymenoptera | Vespa velutina | Asian hornet | 1010 | Vesp v 1 | Phospholipase A1 | 36.1 kDa | 30 of 80 subjects with anaphylaxis grade 2 or 3 to stings of Vespa velutina had IgE binding to natural protein in ImmunoCAP. Unpublished. | 4 | 2020-03-25 00:15:15 | 2020-03-25 00:16:36 | ||
| Animalia Arthropoda | Hymenoptera | Vespa velutina | Asian hornet | 977 | Vesp v 5 | Venom allergen 5 | 23 kDa | Sera from seven of eight hymenoptera sting allergic subjects with systemic symptoms tested positive by IgE binding in reducing gel immunoblots. A negative control did not bind. Data presented in 2013 in the J. Investig Allergol Clin Immunol 23:71 at a Congress: SEAIC annual Symposium in Granada, Spain. Authors Tabar AI, Lombardero M et al. | 4 | 2019-08-28 16:45:22 | 2019-09-06 20:19:58 | ||
| Animalia Arthropoda | Hymenoptera | Vespula flavopilosa | Downy yellowjacket | 636 | Ves f 5 | Antigen 5 | 23 kDa | no information found | 4 | 2003-06-11 12:00:00 | 2019-09-06 20:25:41 | ||
| Animalia Arthropoda | Hymenoptera | Vespula germanica | European wasp | 637 | Ves g 5 | Antigen 5 | 23 kDa | IgE binding to purified Ves g 5 in allergen microarray | 11790727 | 4 | 2003-06-11 12:00:00 | 2019-09-06 20:26:54 | |
| Animalia Arthropoda | Hymenoptera | Vespula maculifrons | Eastern yellowjacket | 638 | Ves m 1 | Phospholipase A1B | 34 kDa | Of 39 sera from yellow jacket-sensitive patients, 18 (46%) showed IgE binding to purified Ves m 1 in RAST. | 6736487 | 4 | 2003-06-03 12:00:00 | 2019-09-06 20:27:56 | |
| Animalia Arthropoda | Hymenoptera | Vespula maculifrons | Eastern yellowjacket | 639 | Ves m 2 | Hyaluronidase | 46 kDa | Of 39 sera from yellow jacket-sensitive patients, 10 (26%) showed IgE binding to purified Ves m 2 in RAST. | 6736487 | 4 | 2003-06-03 12:00:00 | 2019-09-06 20:28:29 | |
| Animalia Arthropoda | Hymenoptera | Vespula maculifrons | Eastern yellowjacket | 640 | Ves m 5 | Antigen 5 | 23 kDa | Of 39 sera from yellow jacket-sensitive patients, 3 (8%) showed IgE binding to purified Ves m 5 in RAST. | 6736487 | 4 | 2003-06-03 12:00:00 | 2019-09-06 20:28:40 | |
| Animalia Arthropoda | Hymenoptera | Vespula pensylvanica | Western yellowjacket | 641 | Ves p 5 | Antigen 5 | 23 kDa | All 39 sera from Vespula-allergic patients showed IgE binding to V.pensylvanica in RAST. The major cross-reactive allergen Ves p 5 was purified and characterized (medline 94044316). | 7065470 | 4 | 2003-06-11 12:00:00 | 2019-09-06 20:35:31 | |
| Animalia Arthropoda | Hymenoptera | Vespula squamosa | Southern yellowjacket | 642 | Ves s 1 | Phospholipase A1B | 34 kDa | Of 23 V.squamosa-allergic patients, 15 showed IgE binding to purified Ves s 1 (identified by phospholipase activity) in RAST | 3989146 | 4 | 2003-06-11 12:00:00 | 2019-09-06 20:36:33 | |
| Animalia Arthropoda | Hymenoptera | Vespula squamosa | Southern yellowjacket | 643 | Ves s 5 | Antigen 5 | 23 kDa | Of 23 V.squamosa-allergic patients, 19 showed IgE binding to purified Ag 5 in RAST | 3989146 | 4 | 2003-06-11 12:00:00 | 2019-09-06 20:36:45 | |
| Animalia Arthropoda | Hymenoptera | Vespula vidua | Widow yellowjacket | 648 | Ves vi 5 | Antigen 5 | 23 kDa | no information found | 4 | 2003-06-12 12:00:00 | 2019-09-06 20:42:29 | ||
| Animalia Arthropoda | Hymenoptera | Vespula vulgaris | Yellowjacket, common wasp | 644 | Ves v 1 | Phospholipase A1B | 34 kDa | Of 31 wasp-allergic patients, who showed increased expression of the basophil activation marker CD203c after stimulation with crude wasp venom extract, 17 (55%) showed increased expression of CD203c after stimulation with purified Ves v 1. | 12403934 | 4 | 2003-06-03 12:00:00 | 2019-09-06 20:38:24 | |
| Animalia Arthropoda | Hymenoptera | Vespula vulgaris | Yellowjacket, common wasp | 645 | Ves v 2 | Hyaluronidase | 38 kDa | Of 31 wasp-allergic patients, who showed increased expression of the basophil activation marker CD203c after stimulation with crude wasp venom extract, 23 (74%) showed increased expression of CD203c after stimulation with purified Ves v 2. | 12403934 | 4 | 2003-06-12 12:00:00 | 2019-09-06 20:39:07 | |
| Animalia Arthropoda | Hymenoptera | Vespula vulgaris | Yellowjacket, common wasp | 646 | Ves v 3 | Dipeptidylpeptidase IV | 100 kDa | 30% of the sera from 36 wasp venom allergic patients had IgE that reacted with rVes v 3.0101 in ELISA. | 4 | 2008-07-11 12:00:00 | 2019-09-06 20:39:55 | ||
| Animalia Arthropoda | Hymenoptera | Vespula vulgaris | Yellowjacket, common wasp | 647 | Ves v 5 | Antigen 5 | 23 kDa | Of 31 wasp-allergic patients, who showed increased expression of the basophil activation marker CD203c after stimulation with crude wasp venom extract, 26 (84%) showed increased expression of CD203c after stimulation with recombinant Ves v 5. | 12403934 | 4 | 2003-06-03 12:00:00 | 2019-09-06 20:41:31 | |
| Animalia Arthropoda | Hymenoptera | Vespula vulgaris | Yellowjacket, common wasp | 736 | Ves v 6 | Vitellogenin | 200 kDa | 11 of 30 individuals with documented allergic reactions to wasp stings (case history, allergen challenge) had IgE that reacted with the recombinant Ves v 6.0101 in ELISA. rVes v 6.0101 was produced by Baculo-based expression in Sf9 insect cells. | 23626765 | 4 | 2012-02-27 12:00:00 | 2024-04-08 16:57:45 | |
| Plantae Eudikotyledons | Fabales | Vigna radiata | Mung bean | 653 | Vig r 1 | Pathogenesis-related protein, PR-10, Bet v 1 family member | 16 kDa | ImmunoCAP analysis detected IgE against Vig r 1 in 80% of mung bean sprout-allergic patients' sera. | 16120087 | 1 | 2006-11-03 12:00:00 | 2019-09-06 20:12:38 | |
| Plantae Eudikotyledons | Fabales | Vigna radiata | Mung bean | 740 | Vig r 2 | 8S Globulin (Vicilin) | 52 kDa | 12 of 12 mung bean allergic patients had IgE that bound to nVig r 2 in immunoblot. | 21631610 | 1 | 2012-05-03 12:00:00 | 2019-09-06 20:13:08 | |
| Plantae Eudikotyledons | Fabales | Vigna radiata | Mung bean | 743 | Vig r 3 | Renamed to Vig r 2.0201; number not available for future submissions | 50 kDa | 21631610 | 1 | 2012-05-03 12:00:00 | 2019-09-06 20:16:26 | ||
| Plantae Eudikotyledons | Fabales | Vigna radiata | Mung bean | 741 | Vig r 4 | Seed albumin | 30 kDa | 8 of 12 mung bean allergic patients had IgE that bound to nVig r 4 in an immunoblot. | 21631610 | 1 | 2012-05-03 12:00:00 | 2019-09-06 20:11:35 | |
| Plantae Eudikotyledons | Fabales | Vigna radiata | Mung bean | 744 | Vig r 5 | Identified as fragment of Vig r 2; number not available for future submissions | 18 kDa | 1 | 2012-05-03 12:00:00 | 2019-09-06 20:17:21 | |||
| Plantae Eudikotyledons | Fabales | Vigna radiata | Mung bean | 742 | Vig r 6 | Cytokinin-specific binding protein (CSBP), Bet v 1 family member | 18 kDa | Of 19 patients who reported allergic reactions or had positive prick-to-prick tests to mung bean sprouts, 63% showed IgE binding to Vig r 6 by ELISA. | 23996905 | 1 | 2012-05-03 12:00:00 | 2024-07-09 18:24:30 | |
| Plantae Eudikotyledons | Vitales | Vitis vinifera | Grape | 654 | Vit v 1 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | Of 14 grape-(or wine)allergic patients, 10 (71%) showed IgE binding to 9 kD Vit v 1 on immunoblot of grape extract. | 12589356 | 1 | 2003-06-24 12:00:00 | 2025-08-25 16:58:24 | |
| Animalia Chordata | Perciformes | Xiphias gladius | Swordfish | 655 | Xip g 1 | Beta-parvalbumin | 11.5 kDa | 12 of 16 (75%) patients with clinical histories of fish allergy showed IgE binding to Xip g 1 on crude swordfish extract by immunoblot. 10 of 14 (71%) allergic patients recognized purified Xip g 1 by IgE ELISA. | 19796207 | 1 | 2008-10-23 12:00:00 | 2020-05-15 00:06:39 | |
| Plantae Eudikotyledons | Sapindales | Zanthoxylum bungeanum | Sichuan pepper | 1057 | Zan b 1 | 2S albumin | 14 kDa (non-reducing); 4 kDa and 10 kDa (reducing) | Five of 5 subjects with food allergy and IgE binding to natural protein and Skin Prick Tests (SPT). IgE postive by dot blot and ELISA. THe purity was evaluated by stained SDS-PAGE. Whole protein sequence not known, PCR used primer in mature coding region. | 38183644 | 1 | 2021-04-03 23:40:10 | 2024-03-08 15:50:49 | |
| Plantae Eudikotyledons | Sapindales | Zanthoxylum bungeanum | Sichuan pepper | 1065 | Zan b 2 | 11S globulin seed storage protein; legumin | 50 kDa non reducingh, 22.3 kDa reducing | Six subjects with claimed allergic responses to reduced glycinin of natural 11S albumin of Sichuan pepper were tested and found to have IgE binding to the reduced form of Sichuan pepper. The subjects had IgE binding to 2S albumin of these proteins by western blot and by ELISA Subjects had IgE binding to four proteins, two of similar MW and sequence and two others with IgE binding to compiled 2S albumins. | 38551197 | 1 | 2021-07-23 04:33:23 | 2024-12-06 14:59:13 | |
| Plantae Liliopsida (monocots) | Poales | Zea mays | Maize | 656 | Zea m 1 | Beta-expansin | 25-35 | All 12 sera from representative patients allergic to grass pollen tested, showed IgE binding to Zea m 1 on immunoblots of Zea mays extract. | 9500760 | 2 | 2003-03-06 12:00:00 | 2019-09-06 19:14:50 | |
| Plantae Liliopsida (monocots) | Poales | Zea mays | Maize | 887 | Zea m 8 | Class IV chitinase | 28.6 kDa | Food allergy case history, 6 of 6 with specific IgE to recombinant protein, 3 of 6 positive with IgE in extract of corn flour | 19669736,28328103 | 1 | 2016-12-15 21:59:32 | 2019-09-06 19:01:40 | |
| Plantae Liliopsida (monocots) | Poales | Zea mays | Maize | 657 | Zea m 12 | Profilin | 14 kDa | Zea m 12 is cross-reactive with wheat profilin tested by both Western Blot and ELISA using a serum pool from patients with food allergy to wheat or maize. | 16364168 | 2 | 2003-03-25 12:00:00 | 2019-09-06 19:48:22 | |
| Plantae Liliopsida (monocots) | Poales | Zea mays | Maize | 658 | Zea m 14 | Non-specific lipid transfer protein type 1 (nsLTP1) | 9 kDa | Sera from 19 (86%) of 22 patients with systemic symptoms after maize ingestion and positive skin prick test responses to maize, recognized the 9-kd LTP protein on immunoblot (identified by N-terminal amino acid sequencing) | 11031346 | 1 | 2003-03-13 12:00:00 | 2025-04-10 18:26:36 | |
| Plantae Liliopsida (monocots) | Poales | Zea mays | Maize | 659 | Zea m 25 | thioredoxin | 13.8 kDa | Zea m 25 is highly cross-reactive with wheat thioredoxin Tri a 25 among 17 bakers with occupational asthma. | 16522470 | 2 | 2006-10-13 12:00:00 | 2019-09-06 19:51:34 | |
| Plantae Eudikotyledons | Rosales | Ziziphus mauritiana | Chinese-date | 660 | Ziz m 1 | Class III chitinase | 30 kDa | rZiz m 1 showed positive skin reactions in 87.5% (7 of 8) of Indian jujube allergic patients. | 16122801, 18435802 | 1 | 2006-11-03 12:00:00 | 2020-03-27 17:02:14 | |
| Plantae Liliopsida (monocots) | Poales | Zoysia matrella | Manila grass | 1015 | Zoy m 1 | Pollen expansin | 30 kDa | 57 patients with allergy to grass pollen were tested by SPT with extracts of Cynodon dactylon and Zoysia matrella. 43 were + to C dactylon, 14 subjects were atopic to Z matrella. each of those species. IgE binding was confirmed to recombinant protein by ELISA and western blot | 2 | 2020-08-07 15:54:10 | 2020-08-07 15:54:40 |