Allergen Details:
| Allergen name: | Pan h 3 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Chordata Order: Siluriformes Species: Pangasianodon hypophthalmus (Striped catfish) NCBI Taxomony ID: 310915 |
| Biochemical name: | Aldolase A |
| MW(SDS-PAGE): | 40 kDa |
| Allergenicity: | Clinical data: A total of 80 fish-allergic patients were included in this study. All had a convincing history of IgE-mediated fish allergy and a sensitization to at least one fish species confirmed by skin prick test with commercial and in-house fish preparations. Eight patients reported typical IgE-mediated allergic reactions after ingestion of Pangasianodon hypophthalmus. As negative controls, 2 non-atopic individuals without history of type I allergy and 8 individuals with allergy to shellfish were used.Among those 10 individuals, only one individual with shellfish allergy demonstrated IgE reactivity to this aldolase A. |
| Allergenicity reference: | PubMed:32860256 |
| Route of allergen exposure: | Food |
| Date Created: | 21/9/2019 |
| Last Updated: | 2021-06-18 16:16:29 |
| Submitter Info: | |
| Name: | Thimo Ruethers; Andreas Lopata |
| Institution: | James Cook University |
| City: | Townsville, Australia |
| Email: | thimo.ruethers@my.jcu.edu.au; andreas.lopata@jcu.edu.au |
| Submission Date: | 2019-07-23 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Pan h 3.0101 | XM_026915836.1 | XP_026771637.1 |