Allergen Details:
| Allergen name: | Pan h 2 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Chordata Order: Siluriformes Species: Pangasianodon hypophthalmus (Striped catfish) NCBI Taxomony ID: 310915 |
| Biochemical name: | beta-enolase |
| MW(SDS-PAGE): | 50 kDa |
| Allergenicity: | 80 subjects with food allergy to striped catfish, Pangasianodon hypophthalmus, were tested by SPT with muscle of this species in saline buffer and 61 were found to have > 5 mm weal. IgE binding to proteins were tested by SDS-PAGE reducing blots and the protein at the identified band was identified by LC-MSMS with 89% coverage compared to genomic predicted protein by quantitative assessment. 18 subjects had positive binding. 10 controls were negative and the other 62 of the fish allergic subjects were negative. |
| Allergenicity reference: | PubMed:32860256 |
| Route of allergen exposure: | Food |
| Date Created: | 23/07/2019 |
| Last Updated: | 2021-01-11 16:51:40 |
| Submitter Info: | |
| Name: | Thimo Ruethers; Andreas Lopata |
| Institution: | James Cook University |
| City: | Townsville, Australia |
| Email: | thimo.ruethers@myjcu.edu.au; andreas.lopata@jcu.edu.au |
| Submission Date: | 2019-07-23 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Pan h 2.01 | XM_034300741 | XP_034156632 |