Allergen Details:
| Allergen name: | Ole e 12 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Lamiales Species: Olea europaea (Olive) NCBI Taxomony ID: 4146 |
| Biochemical name: | Isoflavone reductase |
| MW(SDS-PAGE): | 37 kDa |
| Allergenicity: | Twenty two patients out of 63 recruited with peach allergy also had olive pollen sensitization. These were tested for IgE binding to recombinant E. coli produced protein by ELISA. Earlier work had shown IgE binding to this protein from a different subject as early as 2008. Natural protein was also purified and proteomics demonstrated it was the same protein and had IgE binding in 2D gel blots. |
| Allergenicity reference: | PubMed:26391288 |
| Route of allergen exposure: | Airway |
| Date Created: | 04-04-2018 |
| Last Updated: | 2019-09-04 23:35:48 |
| Submitter Info: | |
| Name: | Maria Teresa Villalba, Lourdes Castro |
| Institution: | Comlutense University of Madrid Biochemistry, ALK-Abello |
| City: | Madrid, Spain |
| Email: | mvillalb@ucm.es, lourdes.castro@alk.net |
| Submission Date: | 2018-03-02 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Ole e 12.0101 | EU927297.1 | ACL13551.1 | E1U332 |