Allergen Details:
| Allergen name: | Jug r 6 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Fagales Species: Juglans regia (English walnut) NCBI Taxomony ID: 51240 |
| Biochemical name: | 7S globulin seed storage protein, vicilin-like protein |
| MW(SDS-PAGE): | 47 kDa |
| Allergenicity: | Sera from nineteen of 76 walnut sensitized subjects demonstrated IgE binding to natural purified protein of 47 kDa, identified as a vicilin-like sugar binding protein. Horse radish peroxidase was used as a CCD inhibiting protein in blocking as there is a glycan sequon. That did not inhibit binding significantly. Extract of hazelnut and natural Cor a 11 as well as Pistachio extract and sesame extract had high inhibition for a few sera by ELISA. |
| Allergenicity reference: | PubMed:30054513 |
| Route of allergen exposure: | Food |
| Date Created: | 09-03-2017 |
| Last Updated: | 2022-04-29 16:00:03 |
| Submitter Info: | |
| Name: | Pawel Dubiela |
| Institution: | Medical University of Vienna |
| City: | Vienna, Austria |
| Email: | pawel.dubiela@meduniwien.ac.at |
| Submission Date: | 2017-01-23 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Jug r 6.0101 | XM_018959147 | XP_018814692 | A0A2I4E5L6 |