Allergen Details:
| Allergen name: | Aed a 10 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Arthropoda Order: Diptera Species: Aedes aegypti (Yellow fever mosquito) NCBI Taxomony ID: 7159 |
| Biochemical name: | Tropomyosin |
| MW(SDS-PAGE): | 32 kDa |
| Allergenicity: | 9 of 15 subjects allergic to Aedes aegypti had IgE binding to this tropomyosin |
| Allergenicity reference: | PubMed:28235135 |
| Route of allergen exposure: | Airway |
| Date Created: | 28-05-2015 |
| Last Updated: | 2019-07-20 18:13:47 |
| Submitter Info: | |
| Name: | Jose Cantillo |
| Institution: | Instituto de Investigaciones Inmunológicas-Universidad de Cartagena |
| City: | Cartagena, Columbia |
| Email: | josefcantillo@gmail.com |
| Submission Date: | 2015-05-28 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Aed a 10.0101 | XM_001655904.1 | XP_001655954.1 | Q17H75 | |
| Aed a 10.0201 | XM_001655898.1 | XP_001655948.1 | Q17H80 |
First public presentation of allergenicity and IgE binding data as a poster presentation abstract in JACI v 133:abstract 354, 2014.
Publication in 2017 from Cantillo suggests patients sensitized to mosquito tropomyosin react via airway exposure.