ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Bla g 3
Lineage: Source: Animalia Arthropoda
Order: Blattodea
Species: Blattella germanica (German cockroach)
Biochemical name:Hemocyanin, Arylphorins/TO Arthropod hemocyanins
MW(SDS-PAGE):78.9 kDa (by mass spectrometry)
Allergenicity:22% of 61 sera from cockroach-allergic adult subjects with a positive skin prick test to B. germanica extract had IgE that bound to recombinant Bla g 3.0101 (E. coli product) in ELISA.
Allergenicity reference:24468254
Route of allergen exposure:Airway
Date Created:18-09-2012
Last Updated:2020-03-24 19:03:02
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Comments

Posted: 24 Mar 2020

Bla g 3.0101 is the only isoform currently in database. It has been published as Bla g 3.02 because it was the variant 2 that FT Chew cloned. There is another variant 1. The variant 2 (GU086323) is ~75-80% more abundant in cockroach extract as analyzed by Samuel Mindaye of the FDA.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Bla g 3.0101GU086323ACY40651D0VNY7