ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Api m 4
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Hymenoptera
Species: Apis mellifera (Honey bee)
NCBI Taxomony ID: 7460
Obsolete name:Api m 3
Biochemical name:Melittin
MW(SDS-PAGE):3 kDa
Allergenicity:Elevated serum IgE antibodies to melittin were found in 7 of 24 honeybee venom-sensitive persons and in 5 of 20 nonsensitive beekeepers, measured by RAST. - None of the 13 bee-allergic patients tested showed upregulation of the activation marker CD203c on basophils in response to Api m 4: medline 2291906.
Allergenicity reference:PubMed:850023
Route of allergen exposure:Injection
Date Created:27-05-2003
Last Updated:2019-07-09 08:28:44
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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Api m 4.0101X02007CAA26038P015012MLT 1BH1