Allergen Details:
| Allergen name: | Sola l 1 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Solanales Species: Solanum lycopersicum (Lycopersicon esculentum) (Tomato) NCBI Taxomony ID: 4081 |
| Obsolete name: | Lyc e 1 |
| Biochemical name: | Profilin |
| MW(SDS-PAGE): | 14 kDa |
| Allergenicity: | Eleven out of 34 food-allergic patients (32%) display IgE binding to both purified profilins. Preincubation of a serum pool with either purified rCap a 2 or rSola l 1 nearly abolished IgE binding to natural Cap a 2 and Sola l 1, respectively. In addition, purified recombinant Cap a 2 was able to inhibit IgE-binding to rSola l 1 by approximately 50%, whereas rSola l 1 completely blocked IgE-binding to rCap a 2 in cross-inhibition assays. |
| Allergenicity reference: | PubMed:12915767 |
| Route of allergen exposure: | Food |
| Date Created: | 08-08-2003 |
| Last Updated: | 2019-09-26 06:45:44 |
| Submitter Info: | |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Sola l 1.0101 | AJ417553 | CAD10377 | Q93YG7 |