Allergen Details:
| Allergen name: | Lep d 2 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Arthropoda Order: Sarcoptiformes Species: Lepidoglyphus destructor (Storage mite) NCBI Taxomony ID: 36936 |
| Obsolete name: | Lep d 1 |
| Biochemical name: | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein |
| MW(SDS-PAGE): | 16 kDa (14 kDa non-red) |
| Allergenicity: | Of 24 L.destructor-sensitive patients tested, 21 showed IgE binding to purified Lep d 2 in RAST. Good correlation between IgE binding to L. destructor and Lep d 2 (r=0.74,PLESSTHAN0.0001). >75% inhibition of IgE binding (serumpool) to Ld by Lep d 2. |
| Allergenicity reference: | PubMed:1611545 |
| Route of allergen exposure: | Airway |
| Date Created: | 13-05-2003 |
| Last Updated: | 2023-11-09 13:30:10 |
| Submitter Info: | |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Lep d 2.0101 | X81399 X83876 X89014 | CAA61419 | P80384 | |
| Lep d 2.0102 | AJ487972 | CAD32313 | P80384 (variant) | |
| Lep d 2.0201 | X83875 | CAA58755 | P80384 (variant) | |
| Lep d 2.0202 | AJ487973 | CAD32314 | P80384 (variant) |