ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Jug r 2
Allergen source: Major taxonomic group: Plantae Magnoliopsida
Order: Fagales
Species: Juglans regia (English walnut)
Biochemical name:Vicilin (7S globulin) seed storage protein
MW(SDS-PAGE):44 kDa
Allergenicity:A recombinant GST-fusion protein of full-length Jug r 2.0101 was shown to bind serum IgE from 9 of 15 patients tested
Allergenicity reference:PubMed:10589017
Route of allergen exposure:Food
Date Created:27-03-2003
Last Updated:2022-06-22 19:03:40
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Comments

Posted: 04 Apr 2020

The full length genomic sequence predicts a longer protein XP_018812170 of 95 kDa, and the allergen identified as Jug r 2.0101 starts at AA position 197. Nesbit and Maleki 2019 JACI 143 in an abstract, identified an N-terminal 171 AA portion of that molecule as an IgE binding stable independent protein fragment

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Jug r 2.0101AF066055AAF18269Q9SEW4 
Jug r 2.0101 (1-173)AF066055 (1-519)AAF18269 (1-173)Q9SEW4 (1-173) 
Jug r 2.0102XM_018956626XP_018812171A0A2I4DYF1 
Jug r 2.0102 (27-367) XP_018812171 (27-367)A0A2I4DYF1 (27-367) 
Jug r 2.0102 (368-789) XP_018812171 (368-789)A0A2I4DYF1 (368-789)