Allergen Details:
| Allergen name: | Hev b 8 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Malpighiales Species: Hevea brasiliensis (Para rubber tree (latex)) NCBI Taxomony ID: 3981 |
| Biochemical name: | Profilin |
| MW(SDS-PAGE): | 15 kDa |
| Allergenicity: | Natural and recombinant purified Hev b 8 gave positive intradermoreaction (ID) in 15/17 of Spina Bifida and 14/14 of latex-allergic patients. 42% of sera from latex-allergic patients had IgE titers of class 1 or higher by enzyme immunoassay, and 39% of them exhibited IgE binding by SDS-PAGE immunoblotting with any natural or recombinant Hev b 8 forms |
| Allergenicity reference: | PubMed:12169172 |
| Route of allergen exposure: | Contact |
| Date Created: | 24-07-2003 |
| Last Updated: | 2019-08-27 02:13:57 |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Hev b 8.0101 | Y15042 | CAA75312 | O65812 | |
| Hev b 8.0102 | AJ132397 | CAB51914 | Q9STB6 | |
| Hev b 8.0201 | AF119365 | AAF34341 | Q9M7N0 | |
| Hev b 8.0202 | AF119366 | AAF34342 | Q9M7M9 | |
| Hev b 8.0203 | AF119367 | AAF34343 | Q9M7M8 | |
| Hev b 8.0204 | AJ243325 | CAB96215 | Q9LEI8 | 1g5u |