Allergen Details:
| Allergen name: | Equ c 2 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Chordata Order: Perissodactyla Species: Equus caballus (Domestic horse) NCBI Taxomony ID: 9796 |
| Obsolete name: | AL21 horse |
| Biochemical name: | Lipocalin |
| MW(SDS-PAGE): | 17 kDa |
| Allergenicity: | IgE binding in immunoblot (11 of 23 patients tested); 33.3% of 21 horse sensitized patients tested showed IgE binding to Equ c 2. See also medline 98237590 March 2020, 20 or 22 of 35 subjects allergic to horse dander were positive in IgE binding to recombinant and natural protein preparations using ImmunoCAP |
| Allergenicity reference: | PubMed:9686871 |
| Route of allergen exposure: | Airway |
| Date Created: | 05-02-2003 |
| Last Updated: | 2020-03-26 19:47:36 |
| Submitter Info: | |
| Name: | Vincent Bulone; Jonas Lidholm |
| Institution: | Centre de Techerches sur les Macromolecules Vegetales; Thermo Fisher Scientific R&D |
| City: | Grenoble cedex 9, France; Uppsala, Sweden |
| Email: | bulone@cermav.cnrs.fr; jonas.lidholm@thermofisher.com |
| Submission Date: | 2003-01-02 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Equ c 2.0101 | MG761768 | AYL64456 | ||
| Equ c 2.0102 | P81217 | P81217 |
Scientists at Thermofisher have isolated and characterized a full length Equ c 2 which is replacing the two partial peptide sequences that were named Equ c 2.0101 and 2.0102 based on peptides, which both had gaps.