Allergen Details:
| Allergen name: | Act c 5 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Ericales Species: Actinidia chinensis (Gold kiwi fruit) NCBI Taxomony ID: 3625 |
| Biochemical name: | Kiwellin |
| MW(SDS-PAGE): | 28 kDa |
| Allergenicity: | Sera from six individual kiwi-allergic subjects (with positive SPT and IgE CAP) showed IgE binding to purified kiwellin from both green kiwi fruit and gold kiwi fruit on immunoblot. |
| Allergenicity reference: | PubMed:18442249 |
| Route of allergen exposure: | Food |
| Date Created: | 28-05-2008 |
| Last Updated: | 2019-06-28 08:09:27 |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Act c 5.0101 | P85261.1 | P85261 | 4PMK | |
| Act c 5.0102 | JX905294.1 | AGC39168.1 | L7TT83 |
The amino acid sequence by Tuppo et al. as P85261 is partial and discontinuous (34aa). In the second part of the discontinuous sequence in the Tuppo paper, there two probable amino acid mismatches with the sequence reported for kiwellins by Maddumage et al. JAFC 2013. which has been added as a separate isoform Act c 5.0102.