Allergen Details:
| Allergen name: | Alt a 1 |
|---|---|
| Allergen source: |
Major taxonomic group: Fungi Ascomycota Order: Pleosporales Species: Alternaria alternata (Alternaria plant rot fungus) NCBI Taxomony ID: 5599 |
| MW(SDS-PAGE): | 16.4 kDa and 15.3 kDa band (30 kDa non-red) |
| Allergenicity: | - Of 57 sera from A. alternaria-sensitive patients, 46 (82%) showed IgE binding to rAlt a 1 on immunoblot. - IgE binding (serumpool, n=34) to A. alternaria extract in ELISA could be inhibited up to 70% by purified native Alt a 1: medline 22659252. - 6 out of 7 patients gave positive skin reactions in response to Alt a 1: medline 22097420 - IgE epitope mapping: medline 22555437 |
| Allergenicity reference: | PubMed:8957113 |
| Route of allergen exposure: | Airway |
| Date Created: | 25-09-2009 |
| Last Updated: | 2019-06-28 18:20:36 |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Alt a 1.0101 | U82633 U86752 | AAB40400 AAB47552 | P79085 | |
| Alt a 1.0102 | AY568627 | AAS75297 | Q6Q128 |