ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Cas s 8
Lineage: Source: Plantae Magnoliopsida
Order: Fagales
Species: Castanea sativa (Chestnut)
Biochemical name:Non-specific lipid transfer protein type 1
MW(SDS-PAGE):12-13 kDa (non-red), 9 kDa (red)
Allergenicity:Significant specific IgE levels to the puri?ed Cas s 8 were found in 7 (58%) of 12 allergic sera by means of ELISA and 6 (66%) of 9 patients by means of SPT.
Allergenicity reference:1099801616950291
Route of allergen exposure:Food
Date Created:20-03-2003
Last Updated:2019-07-20 08:41:21
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Comments

Posted: 02 Nov 2014

The N-terminal sequence listed in the publication by Diaz-Perales et al., 2000, and shown in the IUIS submission, does not match any other known sequence in NCBI at more than 57% identity. It is not clear if this sequence represents a natural chestnut LTP protein.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Cas s 8.0101