Allergen Details:
| Allergen name: | Act d 6 |
|---|---|
| Lineage: |
Source: Plantae Magnoliopsida Order: Ericales Species: Actinidia deliciosa (Green Kiwi fruit) |
| Biochemical name: | Pectin methylesterase inhibitor |
| MW(SDS-PAGE): | 18 |
| Allergenicity: | IgE prevalence: 72% of 50 kiwi allergic patients |
| Route of allergen exposure: | Food |
| Date Created: | Dec 18 2007 2:12PM |
| Last Updated: | 2010-04-29 23:57:55 |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Act d 6.0101 | AB091088.1 | BAC54964 | P83326 |
Although we (IUIS) list pectin methylesterase inhibitor as allergen Act d 6, with a comment of 72% prevalence of IgE binding by kiwi allergic subjects, the is no record of such a publication and the IUIS records are incomplete. As reported by Bublin et al., 2011, Clin Exp Allergy 41:129-136, they did not detect any individual serum sample as having specific IgE binding to Act d 6 using sera from approximately 200 kiwi allergic subjects. Therefore the relevance of this protein as an allergen is questioned. 10 Sept. 2014 REG