ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Cra a 1
Allergen source: Major taxonomic group: Animalia Mollusca
Order: Ostreida
Species: Crassostrea angulata (Portuguese oyster)
NCBI Taxomony ID: 558553
Biochemical name:Tropomyosin
MW(SDS-PAGE):38 kDa
Allergenicity:Thirty patients with reported symptoms after consumption of oyster and a positive crab ImmunoCAP (f23, Thermo Fisher) were tested. Of those, IgE from 10 sera (33%) reacted with recombinant Cra a 1 in a dot-blot. Twenty patients were also tested by a BAT assay with rCra a 1, 5 of which were positive.
Allergenicity reference:PubMed:35848932
Route of allergen exposure:Food
Date Created:2023-07-24
Last Updated:2023-07-24 15:44:58
Submitter Info:
Name:Xiao Yun, Guangming Liu
Institution:Jimei University
City:Xiamen, China
Email:1922168990@qq.com, gmliu@jmu.edu.cn
Submission Date:2022-07-30

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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Cra a 1.0101ON595539UST29548