Allergen Details:
| Allergen name: | Hel a 15 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Asterales Species: Helianthus annuus (Sunflower) NCBI Taxomony ID: 4232 |
| Biochemical name: | 2S albumin seed storage protein, SESA2-1 |
| MW(SDS-PAGE): | 14 kDa |
| Allergenicity: | Sera from 30 subjects were tested. Among them, 17 patients were allergic to sunflower seeds (SFS), with SFS-specific IgE > 0.35 kU/L (ImmunoCAP). Control sera were from 13 patients tolerant to SFS but allergic to other foods. Eleven of 17 (65%) SFS-allergic but none of the 13 SFS-tolerant food-allergic patients had IgE to Hel a 15, as measured by ELISA with the natural purified allergen. |
| Allergenicity reference: | PubMed:38619510 |
| Route of allergen exposure: | Food |
| Date Created: | 2023-06-30 |
| Last Updated: | 2024-04-16 14:23:01 |
| Submitter Info: | |
| Name: | Stéphane Hazebrouck, Hervé Bernard |
| Institution: | French National Research Institute for Agriculture, Food and Environment (INRAE), Université Paris-Saclay |
| City: | Gif-sur-Yvette, France |
| Email: | stephane.hazebrouck@cea.fr, herve.bernard-INRA@cea.fr |
| Submission Date: | 2023-05-12 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Hel a 15.0101 | KR401267 | ALO17641 (amino acids 34-149/150) | A0A161CKQ7 (amino acids 34-149/150) |