ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Art an 14
Allergen source: Major taxonomic group: Plantae Magnoliopsida
Order: Asterales
Species: Artemisia annua (Sweet Wormwood)
Biochemical name:Fructose bisphosphate aldolase
MW(SDS-PAGE):38 kDa
Allergenicity:Sera from 20 pollen-allergic patients (allergic rhinitis and/or asthma) sensitized to Artemisia pollen (ImmunoCAP class >= 3 with A. vulgaris ImmunoCAP) were tested. Of those, 9 (45%) had IgE to recombinant Art an 14.0101, produced in E. coli. In a BAT assay with 3 Art an 14-sensitized patients, 2 of 3 reacted with rArt an 14.0101. In an IgE ELISA with a pool of Art an 14-sensitized sera, a high extent of IgE cross-reactivity with Art si 14 was shown.
Route of allergen exposure:Airway
Date Created:2022-10-17
Last Updated:2022-10-17 17:29:58
Submitter Info:
Name:Ji-Fu Wei, Jin-Lyu Sun
Institution:Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University; State Key Laboratory of Complex Severe and Rare Diseases, PUMCH, CAMS
City:Nanjing, China and Beijing, China
Email:weijifu@hotmail.com, sunjinlv@pumch.cn
Submission Date:2022-10-07

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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Art an 14.0101ON706966