Allergen Details:
| Allergen name: | Cor a 16 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Fagales Species: Corylus avellana (Hazelnut) NCBI Taxomony ID: 13451 |
| Biochemical name: | 7S globulin seed storage protein (vicilin) containing N-terminal alpha-hairpinin (vicilin_N) peptides |
| MW(SDS-PAGE): | 6-8 kDa and 47.5 kDa |
| Allergenicity: | 106 children with suspected hazelnut allergy were tested. All had IgE to hazelnut extract as measured by ImmunoCAP. Of those, 56 (53%) had positive ImmunoCAP to a recombinant protein containing 5 of the 12 N-terminal peptides, while 73 (69%) had IgE to the recombinant mature vicilin (containing only the cupin domains). |
| Allergenicity reference: | PubMed:35851969 |
| Route of allergen exposure: | Food |
| Date Created: | 2022 05 -06 |
| Last Updated: | 2022-12-07 13:58:55 |
| Submitter Info: | |
| Name: | Jonas Lidholm |
| Institution: | Thermo Fisher Scientific, Research and Development |
| City: | Uppsala, Sweden |
| Email: | jonas.lidholm@thermofisher.com |
| Submission Date: | 2022-04-06 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Cor a 16.0101 | ON060881 | UTE00286 | ||
| Cor a 16.0101 (29-714) | ON060881 | UTE00286 (29-714) | ||
| Cor a 16.0101 (715-1133) | ON060881 | UTE00286 (715-1133) |