Allergen Details:
| Allergen name: | Cari p 2 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Brassicales Species: Carica papaya (Papaya) NCBI Taxomony ID: 3649 |
| Biochemical name: | Chymopapain; member of the papain-like cysteine protease (petidase C1) family |
| MW(SDS-PAGE): | 28 kDa |
| Allergenicity: | Ten subjects allergic to ingestion of papaya fruit were tested with recombinant protein produced by a cDNA clone from EMBL accession X97789.1, Taylor et al., protein is in GEPEPT as CAA66378.1. The recombinant protein was characterized also with LC-MSMS on the N-terminus. The rProtein was used for SPT in patients with 3 of 3 testing positive. Also used in a humanized rat basophil leukemia assay and 6 sera were positive. |
| Route of allergen exposure: | Food |
| Date Created: | 2020/11/5 |
| Last Updated: | 2022-05-10 18:43:00 |
| Submitter Info: | |
| Name: | Gaurab Sircar; Moumita Bhowmik |
| Institution: | Visva-Bharati University, Dept. of Botany; Bose Institute Div. of Plant Biology |
| City: | Santiniketan, India; Kolkata, India |
| Email: | sircar.gaurab129@gmail.com; bhowmikmoumita89@gmail.com |
| Submission Date: | 2020-09-29 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Cari p 2.0101 | X97789. | CAA66378 | P14080 |