ALLERGEN NOMENCLATURE
IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Aca s 13
Lineage: Source: Animalia Arthropoda
Order: Astigmata
Species: Acarus siro (Storage mite)
Biochemical name:Fatty acid-binding protein
MW(SDS-PAGE):15
Allergenicity:3 out of 13 (23%) A. siro RAST-positive patients showed strong IgE binding to rAca s 13 on immunoblot
Allergenicity ref.:10474032
Food allergen:No
Date Created:2010-04-29 16:57:55
Last Updated:2012-09-04 15:30:09
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Comments

Posted: 30 Jul 2014

I looked at the IAAI paper by Eriksson, Whitley etc., 1999, PMID 10474032. The data indicates that it matches the description in the submission for the original entry. The sequence identified by them was 192 bp, and 64 aa. A cDNA clone of 396 bp, representing 131 aa with 64 of the first 66 aa identical to the Eriksson sequence was identified by Tan and Chew and the protein sequence entered in NCBI as ABL09307 in 2006. should be added. It is "unusual" that the Eriksson manuscript did not show the cDNA as they report a full length aa sequence. But in the paper teh entire 130 aa is present except "X" for the first (2nd) aa. Therefore I am adding the full length sequence of Tan and Chew. on 30 July 2014

Table of IsoAllergens:

Isoallergen and variants GenBank Nucleotide UniProt PDB
Aca s 13.0101DQ979802B0KZJ6